Search results
- 1.0602573 - BTÚ 2025 RIV NL eng J - Journal Article
Bettazova, N. - Senavova, J. - Kupcová, K. - Sovilj, Dana - Rajmonova, A. - Anděra, Ladislav - Svobodová, K. - Berková, A. - Zemanová, Z. - Daumová, L. - Herman, V. - Davis, R. E. - Trněný, M. - Klener, P. - Havranek, O. - Dolníková, A.
Impact of PIK3CA gain and PTEN loss on mantle cell lymphoma biology and sensitivity to targeted therapies.
Blood Advances. Roč. 8, č. 20 (2024), s. 5279-5289. ISSN 2473-9529. E-ISSN 2473-9537
R&D Projects: GA MŠMT(CZ) LM2023050; GA MZd(CZ) NU21-03-00386; GA MŠMT LX22NPO5102
Institutional support: RVO:86652036
Keywords : tumor-suppressor gene * prostate-cancer * akt * pi3k * inhibition * glycolysis
OECD category: Hematology
Impact factor: 7.4, year: 2023 ; AIS: 2.996, rok: 2023
Method of publishing: Open access
Result website:
https://ashpublications.org/bloodadvances/article/8/20/5279/517397/Impact-of-PIK3CA-gain-and-PTEN-loss-on-mantle-cellDOI: https://doi.org/10.1182/bloodadvances.2024013205
Permanent Link: https://hdl.handle.net/11104/0360010 - 2.0600584 - BTÚ 2025 RIV NL eng J - Journal Article
Dolníková, A. - Kazantsev, D. - Klanova, M. - Pokorná, E. - Sovilj, Dana - Kelemen, Cristina D. - Tuskova, L. - Hoferkova, E. - Mráz, M. - Helman, K. - Curik, N. - Polakova, K. M. - Anděra, Ladislav - Trneny, M. - Klener, P.
Blockage of BCL-XL overcomes venetoclax resistance across BCL2+lymphoid malignancies irrespective of BIM status.
Blood Advances. Roč. 8, č. 13 (2024), s. 3532-3543. ISSN 2473-9529. E-ISSN 2473-9537
R&D Projects: GA MŠMT LX22NPO5102; GA MZd(CZ) NU21-03-00386
Institutional support: RVO:86652036
Keywords : chronic lymphocytic-leukemia * mantle cell lymphoma * homozygous deletions * susceptibility * sensitivity
OECD category: Hematology
Impact factor: 7.4, year: 2023 ; AIS: 2.996, rok: 2023
Method of publishing: Open access
Result website:
https://ashpublications.org/bloodadvances/article/8/13/3532/516030/Blockage-of-BCL-XL-overcomes-venetoclax-resistanceDOI: https://doi.org/10.1182/bloodadvances.2024012906
Permanent Link: https://hdl.handle.net/11104/0357944 - 3.0598931 - BTÚ 2025 RIV NL eng J - Journal Article
Sovilj, Dana - Kelemen, Cristina D. - Dvořáková, Šárka - Zobalová, Renata - Raabová, Helena - Kriška, Ján - Heřmanová, Zuzana - Knotek, Tomáš - Anděrová, Miroslava - Klener, P. - Filimonenko, Vlada - Neužil, Jiří - Anděra, Ladislav
Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak.
Apoptosis. Roč. 29, č. 3-4 (2024), s. 424-438. ISSN 1360-8185. E-ISSN 1573-675X
R&D Projects: GA ČR(CZ) GA19-08772S; GA MŠMT(CZ) LM2023050; GA MZd(CZ) NU23-03-00226; GA ČR(CZ) GA20-05942S; GA ČR(CZ) GX21-04607X; GA MZd(CZ) NU21-03-00386; GA MŠMT(CZ) EF18_046/0016045
Research Infrastructure: Czech-BioImaging III - 90250
Institutional support: RVO:86652036 ; RVO:68378041 ; RVO:68378050
Keywords : predicts poor-prognosis * endoplasmic-reticulum * complex-i * ca2+ * transcription * mcl-1
OECD category: Biochemistry and molecular biology
Impact factor: 6.1, year: 2023 ; AIS: 1.101, rok: 2023
Method of publishing: Open access
Result website:
https://link.springer.com/article/10.1007/s10495-023-01917-2#Ack1DOI: https://doi.org/10.1007/s10495-023-01917-2
Permanent Link: https://hdl.handle.net/11104/0356504 - 4.0584811 - BTÚ 2025 RIV GB eng J - Journal Article
Malarikova, D. - Jorda, R. - Kupcová, K. - Senavova, J. - Dolníková, A. - Pokorná, E. - Kazantsev, D. - Nozickova, K. - Sovilj, Dana - Bellanger, C. - Chiron, D. - Anděra, Ladislav - Kryštof, V. - Strnad, Miroslav - Helman, K. - Klánová, M. - Trněný, M. - Havranek, O. - Klener, P.
Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without iRB1/i deletion.
Experimental Hematology & Oncology. Roč. 13, č. 1 (2024), č. článku 34. E-ISSN 2162-3619
Institutional support: RVO:86652036 ; RVO:61389030
Keywords : cdk4/6 * Cyclin-dependent kinase (CDK) inhibitors * Palbociclib * bcl2 * Venetoclax * rb1 * Mantle cell lymphoma (MCL)
OECD category: Oncology
Impact factor: 9.4, year: 2023 ; AIS: 2.1, rok: 2023
Method of publishing: Open access
Result website:
https://ehoonline.biomedcentral.com/articles/10.1186/s40164-024-00499-2DOI: https://doi.org/10.1186/s40164-024-00499-2
Permanent Link: https://hdl.handle.net/11104/0353392 - 5.0567833 - ÚEM 2023 RIV CH eng J - Journal Article
Horák, Josef - Dolníková, Alexandra - Cumaogullari, O. - Čumová, Andrea - Navvabi, Nazila - Vodičková, Ludmila - Levý, M. - Schneiderová, M. - Liška, V. - Anděra, Ladislav - Vodička, Pavel - Opattová, Alena
MiR-140 leads to MRE11 downregulation and ameliorates oxaliplatin treatment and therapy response in colorectal cancer patients.
Frontiers in Oncology. Roč. 12, oct (2022), č. článku 959407. ISSN 2234-943X. E-ISSN 2234-943X
R&D Projects: GA ČR(CZ) GA20-03997S; GA ČR(CZ) GA21-27902S; GA ČR(CZ) GX21-04607X
Institutional support: RVO:68378041 ; RVO:86652036
Keywords : miR-140 * colorecal cancer * MRE11 * oxaliplatin * therapy response * DNA damage * DNA repair * miRNA
OECD category: Oncology; Oncology (BTO-N)
Impact factor: 4.7, year: 2022 ; AIS: 1.002, rok: 2022
Method of publishing: Open access
Result website:
https://www.frontiersin.org/articles/10.3389/fonc.2022.959407/fullDOI: https://doi.org/10.3389/fonc.2022.959407
Permanent Link: https://hdl.handle.net/11104/0339090File Download Size Commentary Version Access Horák 959407 2022.pdf 7 2.9 MB Author´s preprint open-access - 6.0565105 - BTÚ 2023 RIV US eng J - Journal Article
Ryšánek, D. - Vasicová, P. - Kolla, J. N. - Sedlák, D. - Anděra, Ladislav - Bartek, J. - Hodny, Z.
Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells.
Aging. Roč. 14, č. 16 (2022), s. 6381-6414. ISSN 1945-4589
Institutional support: RVO:86652036
Keywords : homoharringtonine * cellular senescence * bcl-2 * mcl-1 * senolytics
OECD category: Cell biology
Impact factor: 5.2, year: 2022 ; AIS: 1.087, rok: 2022
Method of publishing: Open access
Result website:
https://www.aging-us.com/article/204207/textDOI: https://doi.org/10.18632/aging.204207
Permanent Link: https://hdl.handle.net/11104/0337614 - 7.0556526 - BTÚ 2023 RIV GB eng J - Journal Article
Štemberková-Hubáčková, Soňa - Zobalová, Renata - Dubišová, Mária - Šmigová, J. - Dvořáková, Šárka - Kořínková, Klára - Ezrová, Zuzana - Endaya, Berwini - Blažková, Kristýna - Vlčák, Erik - Brisudová, Petra - Le, Thi Dan Diem - Juhás, Štefan - Rosel, D. - Kelemen, Daniela Cristina - Sovilj, Dana - Vacurová, Eliška - Čajka, Tomáš - Filimonenko, Vlada - Dong, L. - Anděra, Ladislav - Hozák, Pavel - Brabek, J. - Bielcikova, Z. - Štursa, Jan - Werner, Lukáš - Neužil, Jiří
Simultaneous targeting of mitochondrial metabolism and immune checkpoints as a new strategy for renal cancer therapy.
Clinical and Translational Medicine. Roč. 12, č. 3 (2022), č. článku e645. ISSN 2001-1326. E-ISSN 2001-1326
R&D Projects: GA ČR(CZ) GA20-05942S; GA ČR(CZ) GX21-04607X; GA ČR(CZ) GA18-02550S; GA ČR(CZ) GA19-08772S; GA MZd NU21-03-00195; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT LTC19048; GA MŠMT(CZ) LO1609; GA MŠMT(CZ) EF16_013/0001775
Grant - others:AV ČR(CZ) StrategieAV21/18
Program: StrategieAV
Research Infrastructure: Czech-BioImaging II - 90129
Institutional support: RVO:86652036 ; RVO:68378050 ; RVO:67985904 ; RVO:67985823
Keywords : Mitochondrially targeted tamoxifen * Renal cancer * Immunotherapy
OECD category: Pathology
Impact factor: 10.6, year: 2022 ; AIS: 1.963, rok: 2022
Method of publishing: Open access
Result website:
https://onlinelibrary.wiley.com/doi/10.1002/ctm2.645DOI: https://doi.org/10.1002/ctm2.645
Permanent Link: http://hdl.handle.net/11104/0331774File Download Size Commentary Version Access Simultaneous targeting of mitochondrial metabolism and immune checkpoints as a new strategy for renal cancer therapy.pdf 1 7.2 MB Author´s preprint open-access - 8.0554659 - BTÚ 2023 RIV US eng J - Journal Article
Klánová, M. - Kazantsev, D. - Pokorná, E. - Zikmund, T. - Karolová, J. - Behounek, M. - Renesova, N. - Sovilj, Dana - Kelemen, Cristina D. - Helman, K. - Jaksa, R. - Havranek, O. - Anděra, Ladislav - Trněný, M. - Klener, P.
Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas.
Molecular Cancer Therapeutics. Roč. 21, č. 1 (2022), s. 89-99. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR(CZ) GA19-08772S; GA MZd(CZ) NU21-03-00386
Institutional support: RVO:86652036
Keywords : gene-expression * elderly-patients * bcl-2 family * venetoclax * chemotherapy
OECD category: Oncology
Impact factor: 5.7, year: 2022 ; AIS: 1.651, rok: 2022
Method of publishing: Open access
Result website:
https://aacrjournals.org/mct/article/21/1/89/675161/Anti-apoptotic-MCL1-Protein-Represents-CriticalDOI: https://doi.org/10.1158/1535-7163.MCT-21-0511
Permanent Link: http://hdl.handle.net/11104/0331895 - 9.0552825 - ÚEM 2022 RIV CH eng J - Journal Article
Vodička, Pavel - Anděra, Ladislav - Opattová, Alena - Vodičková, Ludmila
The Interactions of DNA Repair, Telomere Homeostasis, and p53 Mutational Status in Solid Cancers: Risk, Prognosis, and Prediction.
Cancers (Basel). Roč. 13, č. 2 (2021), č. článku 479. ISSN 2072-6694. E-ISSN 2072-6694
R&D Projects: GA ČR(CZ) GA19-08772S; GA ČR(CZ) GA19-10543S
Institutional support: RVO:68378041 ; RVO:86652036
Keywords : interactions * DNA damage response * telomere homeostasis * TP53 mutational status * cancer risk * cancer progression * cancer therapy
OECD category: Genetics and heredity (medical genetics to be 3); Genetics and heredity (medical genetics to be 3) (BTO-N)
Impact factor: 6.575, year: 2021 ; AIS: 1.172, rok: 2021
Method of publishing: Open access
Result website:
https://www.mdpi.com/2072-6694/13/3/479DOI: https://doi.org/10.3390/cancers13030479
Permanent Link: http://hdl.handle.net/11104/0327919 - 10.0550596 - BTÚ 2022 RIV CH eng J - Journal Article
Klener, P. - Sovilj, Dana - Renesova, N. - Anděra, Ladislav
BH3 Mimetics in Hematologic Malignancies.
International Journal of Molecular Sciences. Roč. 22, č. 18 (2021), č. článku 10157. ISSN 1661-6596. E-ISSN 1422-0067
R&D Projects: GA MZd(CZ) NU21-03-00386; GA ČR(CZ) GA19-08772S
Institutional support: RVO:86652036
Keywords : apoptosis * venetoclax * BH3 mimetics * hematologic malignancies
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021 ; AIS: 1.064, rok: 2021
Method of publishing: Open access
Result website:
https://www.mdpi.com/1422-0067/22/18/10157DOI: https://doi.org/10.3390/ijms221810157
Permanent Link: http://hdl.handle.net/11104/0326720