Search results

  1. 1.
    0541558 - ÚOCHB 2022 RIV DE eng J - Journal Article
    Smola, Miroslav - Gutten, Ondrej - Dejmek, Milan - Kožíšek, Milan - Evangelidis, Thomas - Tehrani, Zahra Aliakbar - Novotná, Barbora - Nencka, Radim - Birkuš, Gabriel - Rulíšek, Lubomír - Bouřa, Evžen
    Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
    Angewandte Chemie - International Edition. (2021). ISSN 1433-7851
    R&D Projects: GA ČR(CZ) GA20-08772S; GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : conformational analysis * cyclic dinucleotides * entropy * quantum chemistry * strain energy
    OBOR OECD: Organic chemistry
    Impact factor: 12.959, year: 2019
    https://doi.org/10.1002/anie.202016805
    Permanent Link: http://hdl.handle.net/11104/0319101
     
  2. 2.
    0541489 - ÚOCHB 2022 RIV CH eng J - Journal Article
    Gregor, Jiří - Radilová, Kateřina - Brynda, Jiří - Fanfrlík, Jindřich - Konvalinka, Jan - Kožíšek, Milan
    Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase.
    Molecules. Roč. 26, č. 4 (2021), č. článku 1007. ISSN 1420-3049
    R&D Projects: GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : influenza A polymerase * antivirals * pimodivir * VX-787 * resistance
    OBOR OECD: Organic chemistry
    Impact factor: 3.267, year: 2019
    https://doi.org/10.3390/molecules26041007
    Permanent Link: http://hdl.handle.net/11104/0319054
     
  3. 3.
    0541460 - ÚOCHB 2022 RIV US eng J - Journal Article
    Milisavljevič, Nemanja - Konkoľová, Eva - Kozák, Jaroslav - Hodek, Jan - Veselovská, Lucia - Sýkorová, Veronika - Čížek, Karel - Pohl, Radek - Eyer, Luděk - Svoboda, P. - Růžek, Daniel - Weber, Jan - Nencka, Radim - Bouřa, Evžen - Hocek, Michal
    Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses.
    ACS Infectious Diseases. Roč. 7, č. 2 (2021), s. 471-478. ISSN 2373-8227
    R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NU20-05-00472; GA MŠk(CZ) LTAUSA18016; GA MŠk(CZ) EF16_019/0000729
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963 ; RVO:60077344
    Keywords : 7-deazapurine ribonucleosides * monophosphate prodrugs * triphoshates * RNA viruses * 7-deazapurine ribonucleosides monophosphate prodrugs triphoshates RNA viruses antiviral activity
    OBOR OECD: Organic chemistry
    Impact factor: 4.614, year: 2019
    https://doi.org/10.1021/acsinfecdis.0c00829
    Permanent Link: http://hdl.handle.net/11104/0319010
     
  4. 4.
    0541414 - ÚOCHB 2022 RIV FR eng J - Journal Article
    Jansa, J. - Jorda, R. - Škerlová, Jana - Pachl, Petr - Peřina, M. - Řezníčková, E. - Heger, T. - Gucký, T. - Řezáčová, Pavlína - Lyčka, A. - Kryštof, V.
    Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure.
    European Journal of Medicinal Chemistry. Roč. 216 (2021), č. článku 113309. ISSN 0223-5234
    R&D Projects: GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : activity assay * Co-crystal * cyclin-dependent kinase 2 * imidazo[1,2-c]pyrimidin-5(6H)-one * ITC * kinase inhibitor * X-ray crystallography
    OBOR OECD: Biochemistry and molecular biology
    Impact factor: 5.573, year: 2019
    https://doi.org/10.1016/j.ejmech.2021.113309
    Permanent Link: http://hdl.handle.net/11104/0318978
     
  5. 5.
    0541403 - ÚOCHB 2022 RIV GB eng J - Journal Article
    Volek, Martin - Kolesnikova, Sofia - Švehlová, Kateřina - Srb, Pavel - Sgallová, Ráchel - Streckerová, Tereza - Redondo Marín, Juan Alfonso - Veverka, Václav - Curtis, Edward A.
    Overlapping but distinct: a new model for G-quadruplex biochemical specificity.
    Nucleic Acids Research. Roč. 49, č. 4 (2021), s. 1816-1827. ISSN 1362-4962
    R&D Projects: GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    OBOR OECD: Biochemistry and molecular biology
    https://doi.org/10.1093/nar/gkab037
    Permanent Link: http://hdl.handle.net/11104/0318960
     
  6. 6.
    0541374 - ÚOCHB 2022 RIV US eng J - Journal Article
    Kurochka, Andrii - Yushchenko, Dmytro A. - Bouř, Petr - Shvadchak, Volodymyr V.
    Influence of Lipid Membranes on α-Synuclein Aggregation.
    ACS Chemical Neuroscience. Roč. 12, č. 5 (2021), s. 825-830. ISSN 1948-7193
    R&D Projects: GA ČR(CZ) GJ18-06255Y; GA ČR(CZ) GA20-10144S; GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : amyloid * fibril * fibrillization * kinetics * lag time * liposomes
    Subject RIV: BO - Biophysics
    OBOR OECD: Biophysics
    Impact factor: 4.486, year: 2019
    https://doi.org/10.1021/acschemneuro.0c00819
    Permanent Link: http://hdl.handle.net/11104/0318940
     
  7. 7.
    0541366 - ÚOCHB 2022 RIV US eng J - Journal Article
    Kříž, Kristian - Nováček, M. - Řezáč, Jan
    Non-Covalent Interactions Atlas Benchmark Data Sets 3: Repulsive Contacts.
    Journal of Chemical Theory and Computation. Roč. 17, č. 3 (2021), s. 1548-1561. ISSN 1549-9618
    R&D Projects: GA ČR(CZ) GA19-13905S; GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Subject RIV: CF - Physical ; Theoretical Chemistry
    OBOR OECD: Physical chemistry
    Impact factor: 5.011, year: 2019
    https://doi.org/10.1021/acs.jctc.0c01341
    Permanent Link: http://hdl.handle.net/11104/0318928
     
  8. 8.
    0541319 - ÚOCHB 2022 RIV US eng J - Journal Article
    Vavřina, Zdeněk - Gutten, Ondrej - Smola, Miroslav - Zavřel, Martin - Tehrani, Zahra Aliakbar - Charvát, Vilém - Kožíšek, Milan - Bouřa, Evžen - Birkuš, Gabriel - Rulíšek, Lubomír
    Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory.
    Biochemistry. Roč. 60, č. 8 (2021), s. 607-620. ISSN 0006-2960
    R&D Projects: GA ČR(CZ) GA20-08772S; GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Subject RIV: CE - Biochemistry
    OBOR OECD: Biochemistry and molecular biology
    Impact factor: 2.865, year: 2019
    https://doi.org/10.1021/acs.biochem.0c00949
    Permanent Link: http://hdl.handle.net/11104/0318895
     
  9. 9.
    0541262 - ÚOCHB 2022 RIV GB eng J - Journal Article
    Kaminský, Jakub - Andrushchenko, Valery - Bouř, Petr
    Natural and magnetic circular dichroism spectra of nucleosides: effect of the dynamics and environment.
    RSC Advances. Roč. 11, č. 14 (2021), s. 8411-8419. ISSN 2046-2069
    R&D Projects: GA ČR(CZ) GA20-10144S; GA MŠk LTAUSA18085; GA MŠk(CZ) EF16_019/0000729
    Research Infrastructure: e-INFRA CZ - 90140
    Institutional support: RVO:61388963
    Subject RIV: CF - Physical ; Theoretical Chemistry
    OBOR OECD: Physical chemistry
    Impact factor: 3.119, year: 2019
    https://doi.org/10.1039/D1RA00076D
    Permanent Link: http://hdl.handle.net/11104/0318852
     
  10. 10.
    0541252 - ÚOCHB 2022 RIV CZ eng J - Journal Article
    Perlíková, Pavla
    Aryl-7-deazapurinové nukleosidy a jejich biologická aktivita.
    [Aryl-7-deazapurine Nucleosides and their Biological Activity.]
    Chemické listy. Roč. 115, č. 2 (2021), s. 84-90. ISSN 0009-2770
    R&D Projects: GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : nucleoside * 7-deazapurine * cytotoxicity * adenosine kinase
    Subject RIV: CC - Organic Chemistry
    OBOR OECD: Organic chemistry
    Impact factor: 0.390, year: 2019
    http://www.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/3790
    Permanent Link: http://hdl.handle.net/11104/0318840