Search results
- 1.0512141 - ÚEB 2020 RIV NL eng J - Journal Article
Voller, Jiří - Béres, T. - Zatloukal, M. - Džubák, P. - Hajdúch, M. - Doležal, K. - Schmülling, T. - Strnad, Miroslav
Anti-cancer activities of cytokinin ribosides.
Phytochemistry Reviews. Roč. 18, č. 4 (2019), s. 1101-1113. ISSN 1568-7767. E-ISSN 1572-980X
R&D Projects: GA ČR GA17-14007S; GA MŠMT(CZ) LO1304
Institutional support: RVO:61389030
Keywords : Anti-cancer drug * Cancer * Cytokinin * Cytokinin riboside
OECD category: Biochemistry and molecular biology
Impact factor: 4.298, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.1007/s11101-019-09620-4
Permanent Link: http://hdl.handle.net/11104/0302351File Download Size Commentary Version Access 2019_Voller_Phytochemistry Reviews_1101.pdf 1 425.3 KB Other open-access - 2.0509603 - ÚEB 2020 RIV FR eng J - Journal Article
Michalak, K. - Rárová, Lucie - Kubala, M. - Čechová, P. - Strnad, Miroslav - Wicha, J.
Synthesis and evaluation of cytotoxic and Na+/K+-ATP-ase inhibitory activity of selected 5 alpha-oleandrigenin derivatives.
European Journal of Medicinal Chemistry. Roč. 180, OCT 15 (2019), s. 417-429. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR GA17-14007S; GA ČR(CZ) GA19-01383S
Institutional support: RVO:61389030
Keywords : ATP-ase inhibition * Cardenolides * Cytotoxicity * Furan transformation * Partial synthesis
OECD category: Organic chemistry
Impact factor: 5.573, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.1016/j.ejmech.2019.07.028
Permanent Link: http://hdl.handle.net/11104/0300295File Download Size Commentary Version Access 2019_Michalak_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_417.pdf 2 2.5 MB Other open-access - 3.0507922 - ÚEB 2020 RIV US eng J - Journal Article
Voller, Jiří - Zahajská, Lenka - Plíhalová, Lucie - Jeřábková, Jana - Burget, David - Pataki, A.C. - Kryštof, Vladimír - Zatloukal, M. - Brábek, J. - Rösel, D. - Mik, V. - Tkáč, Martin - Pospíšil, T. - Gucký, T. - Doležal, Karel - Strnad, Miroslav
6-Substituted purines as ROCK inhibitors with anti-metastatic activity.
Bioorganic Chemistry. Roč. 90, SI (2019), č. článku 103005. ISSN 0045-2068. E-ISSN 1090-2120
R&D Projects: GA MŠMT(CZ) LO1204; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : Anti-metastatic activity * Melanoma * Protein kinase inhibitor * rock
OECD category: Oncology
Impact factor: 4.831, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.1016/j.bioorg.2019.103005
Permanent Link: http://hdl.handle.net/11104/0298915File Download Size Commentary Version Access 2019_Voller_BIOORGANIC CHEMISTRY_103005.pdf 0 1.6 MB Other open-access - 4.0505109 - ÚEB 2020 RIV US eng J - Journal Article
Jorda, Radek - Havlíček, Libor - Šturc, Antonín - Tušková, D. - Daumová, L. - Alam, M. - Škerlová, Jana - Nekardová, Michaela - Peřina, Miroslav - Pospíšil, Tomáš - Široká, Jitka - Urbánek, Lubor - Pachl, Petr - Řezáčová, Pavlína - Strnad, Miroslav - Klener, P. - Kryštof, Vladimír
3,5,7-Substituted Pyrazolo[4,3- d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models.
Journal of Medicinal Chemistry. Roč. 62, č. 9 (2019), s. 4606-4623. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GA17-14007S; GA ČR(CZ) GBP208/12/G016
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : BIOLOGICAL EVALUATION * CELL-CYCLE * ROSCOVITINE
OECD category: Hematology; Medicinal chemistry (UOCHB-X)
Impact factor: 6.205, year: 2019
Method of publishing: Limited access
http://doi.org/10.1021/acs.jmedchem.9b00189
Permanent Link: http://hdl.handle.net/11104/0296627File Download Size Commentary Version Access 2019_Jorda_JOURNAL OF MEDICINAL CHEMISTRY_4606.pdf 4 4.5 MB Other require - 5.0500160 - ÚEB 2019 RIV US eng J - Journal Article
Samanovic, M. - Hsu, H. C. - Jones, K. - Jones, V. - McNeil, M. - Becker, S. H. - Jordan, A. T. - Strnad, Miroslav - Xu, C. - Jackson, M. - Li, H. - Darwin, K.H.
Cytokinin signaling in Mycobacterium tuberculosis.
mBio. Roč. 9, č. 3 (2018), č. článku e00989-18. ISSN 2161-2129. E-ISSN 2150-7511
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : Acid-fast staining * Cytokinin * Mycobacterium tuberculosis * Regulation * Signaling
OECD category: Microbiology
Impact factor: 6.747, year: 2018
Permanent Link: http://hdl.handle.net/11104/0292280File Download Size Commentary Version Access 2018_Samanovic_MBIO_e00989-18.pdf 6 2.5 MB Other open-access - 6.0496501 - ÚEB 2019 RIV US eng J - Journal Article
Jorda, Radek - Hendrychová, Denisa - Voller, Jiří - Řezníčková, Eva - Gucký, Tomáš - Kryštof, Vladimír
How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases?
Journal of Medicinal Chemistry. Roč. 61, č. 20 (2018), s. 9105-9120. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : small-molecule inhibitors * metastatic breast-cancer * 1st global approval * thermal shift assay * dna-damage response * in-vitro * androgen receptor * cdk inhibitors * highly potent * 2,6,9-trisubstituted purines
OECD category: Oncology
Impact factor: 6.054, year: 2018
Permanent Link: http://hdl.handle.net/11104/0289264File Download Size Commentary Version Access 2018_Jorda_JOURNAL OF MEDICINAL CHEMISTRY_9105.pdf 5 7.3 MB Other open-access - 7.0492257 - ÚEB 2019 RIV US eng J - Journal Article
Cherukupalli, S. - Chandrasekaran, B. - Kryštof, Vladimír - Aleti, R.R. - Sayyad, N. - Merugu, S.R. - Kushwaha, N.D. - Karpoormath, R.
Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors.
Bioorganic Chemistry. Roč. 79, SEP (2018), s. 46-59. ISSN 0045-2068. E-ISSN 1090-2120
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : cancer-therapy * cell-cycle * cyclin-dependent-kinase-2 * roscovitine * lethality * scaffold * targets * mice * Pyrazolo[3,4-d]pyrimidine * Cyclin dependent kinase inhibitor * Anti-proliferative activity * Molecular docking * glide
OECD category: Oncology
Impact factor: 3.926, year: 2018
Permanent Link: http://hdl.handle.net/11104/0285792File Download Size Commentary Version Access 2018_Cherukupalli_BIOORGANIC CHEMISTRY_46.pdf 2 1.1 MB Other open-access - 8.0491930 - ÚEB 2019 RIV NL eng J - Journal Article
Široká, Jitka - Čečková, M. - Urbánek, Lubor - Kryštof, Vladimír - Gucký, Tomáš - Hofman, J. - Strnad, Miroslav - Štaud, F.
LC-MS/MS method for determination of cyclin-dependent kinase inhibitors, BP-14 and BP-20, and its application in pharmacokinetic study in rat.
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. Roč. 1089, JUL 1 (2018), s. 24-32. ISSN 1570-0232. E-ISSN 1873-376X
R&D Projects: GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : seliciclib r-roscovitine * hepatocellular-carcinoma * metabolism * potent * cdc2 * Cyclin-dependent kinase inhibitor * bp-14 * bp-20 * Pharmacokinetics * Tissue distribution
OECD category: Analytical chemistry
Impact factor: 2.813, year: 2018
Permanent Link: http://hdl.handle.net/11104/0285531File Download Size Commentary Version Access 2018_Siroka_JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES_24.pdf 3 995.1 KB Other open-access - 9.0488656 - ÚEB 2019 RIV US eng J - Journal Article
Béres, T. - Dragull, K. - Pospíšil, Jiří - Tarkowská, Danuše - Dančák, M. - Bíba, Ondřej - Tarkowski, P. - Doležal, K. - Strnad, Miroslav
Quantitative Analysis of Ingenol in Euphorbia species via Validated Isotope Dilution Ultra-high Performance Liquid Chromatography Tandem Mass Spectrometry.
Phytochemical Analysis. Roč. 29, č. 1 (2018), s. 23-29. ISSN 0958-0344. E-ISSN 1099-1565
R&D Projects: GA ČR GA17-14007S; GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : Euphorbia genus * ingenol * isotope-dilution method * mass spectrometry * ultra-high performance liquid chromatography
OECD category: Analytical chemistry
Impact factor: 1.963, year: 2018
Permanent Link: http://hdl.handle.net/11104/0283205File Download Size Commentary Version Access 2018_Beres_PHYTOCHEMICAL ANALYSIS_23.pdf 2 299.5 KB Other open-access - 10.0485770 - ÚEB 2018 RIV US eng J - Journal Article
Ramos-Enríquez, M. A. - Vargas-Romero, K. - Rárová, L. - Strnad, Miroslav - Iglesias-Arteaga, M. A.
Synthesis and in vitro anticancer activity of 23(23′)E-benzylidenespirostanols derived from steroid sapogenins.
Steroids. Roč. 128, DEC (2017), s. 85-88. ISSN 0039-128X. E-ISSN 1878-5867
R&D Projects: GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : Aldol condensation * Benzylidenespirostanols * Cancer cell lines * Cytotoxicity * Fibroblasts
OECD category: Oncology
Impact factor: 2.523, year: 2017
Permanent Link: http://hdl.handle.net/11104/0280713File Download Size Commentary Version Access 2017_Ramos-Enriquez_STEROIDS_85.pdf 1 249.2 KB Other open-access