Search results
- 1.0543021 - ÚOCHB 2022 RIV US eng J - Journal Article
Priss, Anastasiia - Afitska, Kseniia - Galkin, Maksym - Yushchenko, Dmytro A. - Shvadchak, Volodymyr V.
Rationally Designed Protein-Based Inhibitor of α-Synuclein Fibrillization in Cells.
Journal of Medicinal Chemistry. Roč. 64, č. 10 (2021), s. 6827-6837. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GJ18-06255Y
Institutional support: RVO:61388963
Keywords : parkinsons disease * aggregation * brain
OECD category: Biochemistry and molecular biology
Impact factor: 8.039, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acs.jmedchem.1c00086
Permanent Link: http://hdl.handle.net/11104/0320331 - 2.0518337 - ÚOCHB 2021 RIV GB eng J - Journal Article
Afitska, Kseniia - Priss, Anastasiia - Yushchenko, Dmytro A. - Shvadchak, Volodymyr V.
Structural Optimization of Inhibitors of α-Synuclein Fibril Growth: Affinity to the Fibril End as a Crucial Factor.
Journal of Molecular Biology. Roč. 432, č. 4 (2020), s. 967-977. ISSN 0022-2836. E-ISSN 1089-8638
R&D Projects: GA ČR(CZ) GJ18-06255Y
Institutional support: RVO:61388963
Keywords : amyloid * inhibitor * aggregation * kinetics * dissociation constant
OECD category: Biochemistry and molecular biology
Impact factor: 5.469, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0022283619306849?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0304358 - 3.0511507 - ÚOCHB 2020 RIV US eng J - Journal Article
Kyriukha, Yevhenii A. - Afitska, Kseniia - Kurochka, Andrii - Sachan, Shubhra - Galkin, Maksym - Yushchenko, Dmytro A. - Shvadchak, Volodymyr V.
α-Synuclein Dimers as Potent Inhibitors of Fibrillization.
Journal of Medicinal Chemistry. Roč. 62, č. 22 (2019), s. 10342-10351. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GJ18-06255Y
Institutional support: RVO:61388963
Keywords : protecting groups * aggregation * binding
OECD category: Biochemistry and molecular biology
Impact factor: 6.205, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.9b01400
Permanent Link: http://hdl.handle.net/11104/0301755 - 4.0507378 - ÚOCHB 2020 RIV NL eng J - Journal Article
Afitska, Kseniia - Fučíková, A. - Shvadchak, Volodymyr V. - Yushchenko, Dmytro A.
α-Synuclein aggregation at low concentrations.
Biochimica Et Biophysica Acta-Proteins and Proteomics. Roč. 1867, 7/8 (2019), s. 701-709. ISSN 1570-9639. E-ISSN 1878-1454
R&D Projects: GA ČR(CZ) GJ18-06255Y
Institutional support: RVO:61388963
Keywords : amyloid fibrils * kinetics * fibril disaggregation * critical concentration * intermediates * Kd
OECD category: Biochemistry and molecular biology
Impact factor: 2.371, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S1570963919300834?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0298378 - 5.0490459 - ÚOCHB 2019 RIV DE eng J - Journal Article
Shvadchak, Volodymyr V. - Afitska, Kseniia - Yushchenko, Dmytro A.
Inhibition of alpha-Synuclein Amyloid Fibril Elongation by Blocking Fibril Ends.
Angewandte Chemie - International Edition. Roč. 57, č. 20 (2018), s. 5690-5694. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GJ18-06255Y
Institutional support: RVO:61388963
Keywords : alpha-synuclein * amyloid fibrils * inhibitors * kinetics * neurodegenerative disorders
OECD category: Biophysics
Impact factor: 12.257, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284697 - 6.0485440 - ÚOCHB 2018 RIV US eng J - Journal Article
Afitska, Kseniia - Fučíková, A. - Shvadchak, Volodymyr V. - Yushchenko, Dmytro A.
Modification of C Terminus Provides New Insights into the Mechanism of alpha-Synuclein Aggregation.
Biophysical Journal. Roč. 113, č. 10 (2017), s. 2182-2191. ISSN 0006-3495. E-ISSN 1542-0086
Institutional support: RVO:61388963
Keywords : alpha-synuclein * aggregation * kinetics
OECD category: Biophysics
Impact factor: 3.495, year: 2017
Permanent Link: http://hdl.handle.net/11104/0280467 - 7.0475308 - ÚOCHB 2018 RIV NL eng J - Journal Article
Shvadchak, Volodymyr V. - Kucherak, Oleksandr - Afitska, Kseniia - Dziuba, D. - Yushchenko, Dmytro A.
Environmentally sensitive probes for monitoring protein-membrane interactions at nanomolar concentrations.
Biochimica Et Biophysica Acta-Biomembranes. Roč. 1859, č. 5 (2017), s. 852-859. ISSN 0005-2736. E-ISSN 1879-2642
Institutional support: RVO:61388963
Keywords : solvatochromic probes * fluorescence * protein-membrane interaction * affinity * binding stoichiometry * alpha-synuclein
OECD category: Biochemistry and molecular biology
Impact factor: 3.438, year: 2017
Permanent Link: http://hdl.handle.net/11104/0272145