Search results

  1. 1.
    0542237 - BTÚ 2022 RIV GB eng J - Journal Article
    Ezrová, Zuzana - Nahácka, Zuzana - Štursa, Jan - Werner, Lukáš - Vlčák, Erik - Králová Viziová, Petra - Berridge, M.V. - Sedláček, Radislav - Zobalová, Renata - Rohlena, Jakub - Boukalová, Štěpána - Neužil, Jiří
    SMAD4 loss limits the vulnerability of pancreatic cancer cells to complex I inhibition via promotion of mitophagy.
    Oncogene. Roč. 40, č. 14 (2021), s. 2539-2552. ISSN 0950-9232. E-ISSN 1476-5594
    R&D Projects: GA MZd(CZ) NV16-31604A; GA ČR GA19-20553S; GA ČR(CZ) GA20-18513S; GA ČR(CZ) GJ20-11724Y; GA ČR(CZ) GA18-02550S; GA MŠMT(CZ) EF16_027/0008353; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT LO1220; GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) EF16_013/0001775; GA MŠMT(CZ) LM2018126; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395
    Institutional support: RVO:86652036 ; RVO:68378050
    Keywords : biguanide derivative * reduced nicotinamide adenine dinucleotide dehydrogenase (ubiquinone) * Smad4 protein
    OECD category: Genetics and heredity (medical genetics to be 3); Genetics and heredity (medical genetics to be 3) (UMG-J)
    Impact factor: 8.756, year: 2021
    Method of publishing: Limited access
    Result website:
    https://www.nature.com/articles/s41388-021-01726-4?elqTrackId=c7cc7e8c0df94ff7a61453bf09cfb167DOI: https://doi.org/10.1038/s41388-021-01726-4
    Permanent Link: http://hdl.handle.net/11104/0319702
     
  2. 2.
    0535309 - BTÚ 2021 RIV GB eng J - Journal Article
    Gaetani, S. - Monaco, F. - Alessandrini, F. - Tagliabracci, A. - Sabbatini, A. - Bracci, M. - Valentino, M. - Neužil, Jiří - Amati, M. - Santarelli, L. - Tomasetti, M.
    Mechanism of miR-222 and miR-126 regulation and its role in asbestos-induced malignancy.
    International Journal of Biochemistry and Cell Biology. Roč. 121, APR 2020 (2020), č. článku 105700. ISSN 1357-2725. E-ISSN 1878-5875
    R&D Projects: GA MZd(CZ) NV16-31604A
    Institutional support: RVO:86652036
    Keywords : host gene egfl7 * dna methylation * cancer * miR-222
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.085, year: 2020
    Method of publishing: Open access
    Result website:
    https://www.sciencedirect.com/science/article/pii/S1357272520300170?via%3DihubDOI: https://doi.org/10.1016/j.biocel.2020.105700
    Permanent Link: http://hdl.handle.net/11104/0313411
     
  3. 3.
    0521391 - BTÚ 2020 RIV US eng J - Journal Article
    Santarelli, L. - Gaetani, S. - Monaco, F. - Bracci, M. - Valentino, M. - Amati, M. - Rubini, C. - Sabbatini, A. - Pasquini, E. - Zanotta, N. - Comar, M. - Neužil, Jiří - Tomasetti, M. - Bovenzi, M.
    Four-miRNA Signature to Identify Asbestos-Related Lung Malignancies.
    Cancer Epidemiology Biomarkers & Prevention. Roč. 28, č. 1 (2019), s. 119-126. ISSN 1055-9965. E-ISSN 1538-7755
    R&D Projects: GA MZd(CZ) NV16-31604A
    Institutional support: RVO:86652036
    Keywords : environmental exposure * mir-126 * cancer * mesothelioma * micrornas
    OECD category: Oncology
    Impact factor: 4.344, year: 2019
    Method of publishing: Open access
    Result website:
    https://cebp.aacrjournals.org/content/28/1/119DOI: https://doi.org/10.1158/1055-9965.EPI-18-0453
    Permanent Link: http://hdl.handle.net/11104/0306039
     
  4. 4.
    0521316 - BTÚ 2020 RIV NL eng J - Journal Article
    Monaco, F. - Gaetani, S. - Alessandrini, F. - Tagliabracci, A. - Bracci, M. - Valentino, M. - Neužil, Jiří - Amati, M. - Bovenzi, M. - Tomasetti, M. - Santarelli, L.
    Exosomal transfer of miR-126 promotes the anti-tumour response in malignant mesothelioma: Role of miR-126 in cancer-stroma communication.
    Cancer letters. Roč. 463, č. 2019 (2019), s. 27-36. ISSN 0304-3835. E-ISSN 1872-7980
    R&D Projects: GA MZd(CZ) NV16-31604A
    Institutional support: RVO:86652036
    Keywords : pleural mesothelioma * angiogenesis * cells * repression * apoptosis
    OECD category: Oncology
    Impact factor: 7.360, year: 2019
    Method of publishing: Open access
    Result website:
    https://www.sciencedirect.com/science/article/abs/pii/S0304383519304240?via%3DihubDOI: https://doi.org/10.1016/j.canlet.2019.08.001
    Permanent Link: http://hdl.handle.net/11104/0305953
     
  5. 5.
    0508075 - BTÚ 2020 RIV GB eng J - Journal Article
    Grimolizzi, F. - Monaco, F. - Leoni, F. - Bracci, M. - Staffolani, S. - Bersaglieri, C. - Gaetani, S. - Valentino, M. - Amati, M. - Rubini, C. - Saccucci, F. - Neužil, Jiří - Tomasetti, M. - Santarelli, L.
    Exosomal miR-126 as a circulating biomarker in non-small-cell lung cancer regulating cancer progression.
    Scientific Reports. Roč. 7, NOV 10 2017 (2017), č. článku 15277. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA MZd(CZ) NV16-31604A; GA MŠMT(CZ) ED1.1.00/02.0109
    Keywords : extracellular vesicles * inhibit angiogenesis * micrornas * growth
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.122, year: 2017
    Method of publishing: Open access
    Result website:
    https://www.nature.com/articles/s41598-017-15475-6DOI: https://doi.org/10.1038/s41598-017-15475-6
    Permanent Link: http://hdl.handle.net/11104/0299074
     
  6. 6.
    0504151 - BTÚ 2020 RIV US eng J - Journal Article
    Bajziková, Martina - Kovářová, Jaromíra - Coelho, Ana R. - Boukalová, Štěpána - Oh, S. - Rohlenová, Kateřina - Švec, David - Hubáčková, Soňa - Endaya, B. - Judasová, Kateřina - Bezawork-Geleta, A. - Klučková, Katarína - Chatre, L. - Zobalová, Renata - Nováková, Anna - Váňová, Kateřina - Ezrová, Zuzana - Maghzal, G. J. - Novais, Silvia Magalhaes - Olsinova, M. - Krobová, Linda - An, Y. J. - Davidová, Eliška - Nahácka, Zuzana - Sobol, Margaryta - Cunha-Oliveira, T. - Sandoval-Acuna, Cristian - Strnad, Hynek - Zhang, T. - Huynh, T. - Serafim, T. L. - Hozák, Pavel - Sardao, V. A. - Koopman, W. J. H. - Ricchetti, M. - Oliveira, P. J. - Kolář, František - Kubista, Mikael - Truksa, Jaroslav - Dvořáková-Hortová, Kateřina - Pacak, K. - Gürlich, R. - Stocker, R. - Zhou, Y. - Berridge, M.V. - Park, S. - Dong, L. - Rohlena, Jakub - Neužil, Jiří
    Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
    Cell Metabolism. Roč. 29, č. 2 (2019), s. 399-416. ISSN 1550-4131. E-ISSN 1932-7420
    R&D Projects: GA ČR GA15-02203S; GA ČR GA16-12719S; GA ČR GA17-20904S; GA ČR GA16-22823S; GA ČR(CZ) GA16-12816S; GA ČR(CZ) GA18-11275S; GA ČR(CZ) GA18-02550S; GA MZd(CZ) NV16-31604A; GA MZd(CZ) NV17-30138A; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) LM2015062; GA ČR(CZ) GJ18-24753Y; GA MŠMT(CZ) EF16_013/0001775
    Institutional support: RVO:86652036 ; RVO:67985823 ; RVO:68378050
    Keywords : ELECTRON-TRANSPORT CHAIN * PANCREATIC-CANCER * MITOCHONDRIA
    OECD category: Cell biology; Physiology (including cytology) (FGU-C); Cell biology (UMG-J)
    Impact factor: 21.567, year: 2019
    Method of publishing: Open access
    Result website:
    https://www.sciencedirect.com/science/article/pii/S1550413118306466?via%3DihubDOI: https://doi.org/10.1016/j.cmet.2018.10.014
    Permanent Link: http://hdl.handle.net/11104/0295861
     
     
  7. 7.
    0496022 - BTÚ 2019 RIV GB eng J - Journal Article
    Tomasetti, M. - Re, M. - Monaco, F. - Gaetani, S. - Rubini, C. - Bertini, A. - Pasquini, E. - Bersaglieri, C. - Bracci, M. - Staffolani, S. - Colomba, M. - Gregorini, A. - Valentino, M. - Tagliabracci, A. - Bovenzi, M. - Neužil, Jiří - Amati, M. - Santarelli, L.
    MiR-126 in intestinal-type sinonasal adenocarcinomas: exosomal transfer of MiR-126 promotes anti-tumour responses.
    BMC Cancer. Roč. 18, SEP 17 2018 (2018), č. článku 896. ISSN 1471-2407. E-ISSN 1471-2407
    R&D Projects: GA MZd(CZ) NV16-31604A
    Keywords : Intestinal-type sinonasal adenocarcinomas * Inflammatory polyps * Sinonasal-inverted papillomas
    OECD category: Oncology
    Impact factor: 2.933, year: 2018
    DOI: https://doi.org/10.1186/s12885-018-4801-z
    Permanent Link: http://hdl.handle.net/11104/0288867
     
  8. 8.
    0492368 - BTÚ 2019 RIV GB eng J - Journal Article
    Cuyas, E. - Verdura, S. - Llorach-Pares, L. - Fernandez-Arroyo, S. - Luciano-Mateo, F. - Cabre, N. - Štursa, Jan - Werner, Lukáš - Martin-Castillo, B. - Viollet, B. - Neužil, Jiří - Joven, J. - Nonell-Canals, A. - Sanchez-Martinez, M. - Menendez, J. A.
    Metformin directly targets the H3K27me3 demethylase KDM6A/UTX.
    Aging Cell. Roč. 17, č. 4 (2018), č. článku e12772. ISSN 1474-9718. E-ISSN 1474-9726
    R&D Projects: GA MZd(CZ) NV16-31604A; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:86652036
    Keywords : aging * cancer * computational screening * chemoinformatics * metformin
    OECD category: Cell biology
    Impact factor: 7.346, year: 2018
    DOI: https://doi.org/10.1111/acel.12772
    Permanent Link: http://hdl.handle.net/11104/0285925
     
  9. 9.
    0481503 - BTÚ 2018 RIV US eng J - Journal Article
    Blecha, Jan - Novais, Silvia Magalhaes - Rohlenová, Kateřina - Novotná, Eliška - Lettlová, Sandra - Schmitt, S. - Zischka, H. - Neužil, Jiří - Rohlena, Jakub
    Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death.
    Free Radical Biology and Medicine. Roč. 112, NOV 2017 (2017), s. 253-266. ISSN 0891-5849. E-ISSN 1873-4596
    R&D Projects: GA ČR GA16-22823S; GA ČR GA17-20904S; GA ČR GA16-12719S; GA MZd(CZ) NV16-31604A; GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:86652036
    Keywords : Electron transport chain * Supercomplexes * Antioxidant defense * SOD2
    OECD category: Biochemistry and molecular biology
    Impact factor: 6.020, year: 2017
    DOI: https://doi.org/10.1016/j.freeradbiomed.2017.07.033
    Permanent Link: http://hdl.handle.net/11104/0277051
     
     
  10. 10.
    0469007 - BTÚ 2017 RIV US eng J - Journal Article
    Boukalová, Štěpána - Štursa, J. - Werner, L. - Ezrová, Zuzana - Černý, Jiří - Bezawork-Geleta, A. - Pecinová, Alena - Dong, L. - Drahota, Zdeněk - Neužil, Jiří
    Mitochondrial Targeting of Metformin Enhances Its Activity against Pancreatic Cancer.
    Molecular Cancer Therapeutics. Roč. 15, č. 12 (2016), s. 2875-2886. ISSN 1535-7163. E-ISSN 1538-8514
    R&D Projects: GA ČR GA15-02203S; GA MZd(CZ) NV16-31604A; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:86652036 ; RVO:67985823
    Keywords : ELECTRON-TRANSPORT CHAIN * RESPIRATORY COMPLEX-II * SUCCINATE
    Subject RIV: FD - Oncology ; Hematology; EB - Genetics ; Molecular Biology (FGU-C)
    Impact factor: 5.764, year: 2016
    DOI: https://doi.org/10.1158/1535-7163.MCT-15-1021
    Permanent Link: http://hdl.handle.net/11104/0266913
     
     


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