Search results
- 1.0498520 - ÚOCHB 2019 RIV US eng J - Journal Article
Tokarenko, Anna - Lišková, B. - Smolen, Sabina - Táborská, N. - Tichý, Michal - Gurská, S. - Perlíková, Pavla - Frydrych, I. - Tloušťová, Eva - Znojek, P. - Mertlíková-Kaiserová, Helena - Poštová Slavětínská, Lenka - Pohl, Radek - Klepetářová, Blanka - Khalid, N. U. A. - Wenren, Y. - Laposa, R. R. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 61, č. 20 (2018), s. 9347-9359. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : hepatitis C virus * adenosine kinase inhibitors * mitochondrial RNA polymerase
OECD category: Organic chemistry
Impact factor: 6.054, year: 2018
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.8b01258
Permanent Link: http://hdl.handle.net/11104/0291128File Download Size Commentary Version Access 0498520.pdf 9 1.9 MB Publisher’s postprint open-access - 2.0495509 - ÚOCHB 2019 RIV DE eng J - Journal Article
Ghosh, Ketaki - Perlíková, Pavla - Havlíček, Vojtěch - Yang, Chao - Pohl, Radek - Tloušťová, Eva - Hodek, Jan - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Isomeric Naphtho-Fused 7-Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids.
European Journal of Organic Chemistry. Roč. 2018, č. 37 (2018), s. 5092-5108. ISSN 1434-193X. E-ISSN 1099-0690
R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : nucleosides * nucleotides * fused heterocycles * cytostatics * antiviral agents
OECD category: Organic chemistry
Impact factor: 3.029, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288477 - 3.0493609 - ÚOCHB 2019 RIV DE eng J - Journal Article
Tichý, Michal - Smolen, Sabina - Deingruber, Tomáš - Džubák, P. - Pohl, Radek - Poštová Slavětínská, Lenka - Hajdúch, M. - Hocek, Michal
Thienopyrrolo[2, 3-d]pyrimidines, New Tricyclic Nucleobase Analogues: Synthesis and Biological Activities.
ChemistrySelect. Roč. 3, č. 31 (2018), s. 9144-9149. ISSN 2365-6549. E-ISSN 2365-6549
R&D Projects: GA ČR(CZ) GA16-00178S
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : fused heterocycles * nucleobases * nucleosides * cytostatics * antivirals
OECD category: Organic chemistry
Impact factor: 1.716, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286945 - 4.0491246 - ÚOCHB 2019 RIV US eng J - Journal Article
Sabat, Nazarii - Poštová Slavětínská, Lenka - Klepetářová, Blanka - Hocek, Michal
C-H Imidation of 7-Deazapurines.
ACS Omega. Roč. 3, č. 4 (2018), s. 4674-4678. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA ČR(CZ) GA16-00178S; GA MŠMT(CZ) LO1304
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : cross-coupling reactions * pyrimidine nucleosides * bond functionalization
OECD category: Organic chemistry
Impact factor: 2.584, year: 2018
https://pubs.acs.org/doi/10.1021/acsomega.8b00520
Permanent Link: http://hdl.handle.net/11104/0285280 - 5.0480866 - ÚOCHB 2018 RIV US eng J - Journal Article
Perlíková, Pavla - Hocek, Michal
Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides.
Medicinal Research Reviews. Roč. 37, č. 6 (2017), s. 1429-1460. ISSN 0198-6325. E-ISSN 1098-1128
R&D Projects: GA ČR(CZ) GA16-00178S
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : antivirals * cytostatics * deazapurines * nucleosides * nucleotides
OECD category: Organic chemistry
Impact factor: 8.290, year: 2017
http://onlinelibrary.wiley.com/doi/10.1002/med.21465/full
Permanent Link: http://hdl.handle.net/11104/0276543File Download Size Commentary Version Access 0480866.pdf 3 1.3 MB Publisher’s postprint open-access - 6.0480257 - ÚOCHB 2018 RIV DE eng J - Journal Article
Sabat, Nazarii - Smolen, Sabina - Nauš, Petr - Perlíková, Pavla - Cebová, M. - Poštová Slavětínská, Lenka - Hocek, Michal
Synthesis of 2,6-Substituted 7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted 5-(Het)aryl-pyrrolo[2,3-d]pyrimidines).
Synthesis. Roč. 49, č. 20 (2017), s. 4623-4650. ISSN 0039-7881. E-ISSN 1437-210X
R&D Projects: GA ČR(CZ) GA16-00178S; GA MZd(CZ) NV15-31984A
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : deazapurines * pyrrolo[2,3-d]pyrimidines * nucleobases * Suzuki-Miyaura cross-coupling * deprotection * demethylation
OECD category: Organic chemistry
Impact factor: 2.722, year: 2017
Permanent Link: http://hdl.handle.net/11104/0276103 - 7.0480133 - ÚOCHB 2018 RIV GB eng J - Journal Article
Konč, Juraj - Tichý, Michal - Pohl, Radek - Hodek, Jan - Džubák, P. - Hajdúch, M. - Hocek, Michal
Sugar modified pyrimido[4,5-b] indole nucleosides: synthesis and antiviral activity.
MedChemComm. Roč. 8, č. 9 (2017), s. 1856-1862. ISSN 2040-2503. E-ISSN 2040-2511
R&D Projects: GA ČR(CZ) GA16-00178S
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : hepatitis C virus * modified derivatives * ribonucleosides
OECD category: Organic chemistry
Impact factor: 2.342, year: 2017
http://pubs.rsc.org/en/content/articlehtml/2017/md/c7md00319f
Permanent Link: http://hdl.handle.net/11104/0276042 - 8.0475217 - ÚOCHB 2018 RIV US eng J - Journal Article
Tichý, Michal - Smolen, Sabina - Tloušťová, Eva - Pohl, Radek - Oždian, T. - Hejtmánková, K. - Lišková, B. - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 60, č. 6 (2017), s. 2411-2424. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : adenosine kinase inhibitors * cross-coupling reactions * cytotoxic nucleoside analogs
OECD category: Organic chemistry
Impact factor: 6.253, year: 2017
http://pubs.acs.org/doi/full/10.1021/acs.jmedchem.6b01766
Permanent Link: http://hdl.handle.net/11104/0272060File Download Size Commentary Version Access 0475217.pdf 5 1.1 MB Publisher’s postprint open-access - 9.0475194 - ÚOCHB 2018 RIV DE eng J - Journal Article
Downey, Alan Michael - Pohl, Radek - Roithová, J. - Hocek, Michal
Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism.
Chemistry - A European Journal. Roč. 23, č. 16 (2017), s. 3910-3917. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA TA ČR(CZ) TE01020028; GA ČR(CZ) GA16-00178S
Institutional support: RVO:61388963
Keywords : epoxides * glycosylation * nucleosides * riboses * synthesis design
OECD category: Organic chemistry
Impact factor: 5.160, year: 2017
Permanent Link: http://hdl.handle.net/11104/0272048 - 10.0466099 - ÚOCHB 2017 RIV US eng J - Journal Article
Sabat, Nazarii - Poštová Slavětínská, Lenka - Klepetářová, Blanka - Hocek, Michal
C-H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7-and 9-Deazapurine-8-phosphonate Derivatives.
Journal of Organic Chemistry. Roč. 81, č. 19 (2016), s. 9507-9514. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA16-00178S; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : cross-coupling reactions * acyclic nucleoside phosphonates * biological activity
Subject RIV: CC - Organic Chemistry
Impact factor: 4.849, year: 2016
Permanent Link: http://hdl.handle.net/11104/0264499