Search results

  1. 1.
    0498520 - ÚOCHB 2019 RIV US eng J - Journal Article
    Tokarenko, Anna - Lišková, B. - Smolen, Sabina - Táborská, N. - Tichý, Michal - Gurská, S. - Perlíková, Pavla - Frydrych, I. - Tloušťová, Eva - Znojek, P. - Mertlíková-Kaiserová, Helena - Poštová Slavětínská, Lenka - Pohl, Radek - Klepetářová, Blanka - Khalid, N. U. A. - Wenren, Y. - Laposa, R. R. - Džubák, P. - Hajdúch, M. - Hocek, Michal
    Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
    Journal of Medicinal Chemistry. Roč. 61, č. 20 (2018), s. 9347-9359. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064
    Grant - others:AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : hepatitis C virus * adenosine kinase inhibitors * mitochondrial RNA polymerase
    OECD category: Organic chemistry
    Impact factor: 6.054, year: 2018
    https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.8b01258
    Permanent Link: http://hdl.handle.net/11104/0291128
    FileDownloadSizeCommentaryVersionAccess
    0498520.pdf91.9 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0495509 - ÚOCHB 2019 RIV DE eng J - Journal Article
    Ghosh, Ketaki - Perlíková, Pavla - Havlíček, Vojtěch - Yang, Chao - Pohl, Radek - Tloušťová, Eva - Hodek, Jan - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
    Isomeric Naphtho-Fused 7-Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids.
    European Journal of Organic Chemistry. Roč. 2018, č. 37 (2018), s. 5092-5108. ISSN 1434-193X. E-ISSN 1099-0690
    R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064
    Grant - others:AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : nucleosides * nucleotides * fused heterocycles * cytostatics * antiviral agents
    OECD category: Organic chemistry
    Impact factor: 3.029, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0288477
     
     
  3. 3.
    0493609 - ÚOCHB 2019 RIV DE eng J - Journal Article
    Tichý, Michal - Smolen, Sabina - Deingruber, Tomáš - Džubák, P. - Pohl, Radek - Poštová Slavětínská, Lenka - Hajdúch, M. - Hocek, Michal
    Thienopyrrolo[2, 3-d]pyrimidines, New Tricyclic Nucleobase Analogues: Synthesis and Biological Activities.
    ChemistrySelect. Roč. 3, č. 31 (2018), s. 9144-9149. ISSN 2365-6549. E-ISSN 2365-6549
    R&D Projects: GA ČR(CZ) GA16-00178S
    Grant - others:AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : fused heterocycles * nucleobases * nucleosides * cytostatics * antivirals
    OECD category: Organic chemistry
    Impact factor: 1.716, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0286945
     
     
  4. 4.
    0491246 - ÚOCHB 2019 RIV US eng J - Journal Article
    Sabat, Nazarii - Poštová Slavětínská, Lenka - Klepetářová, Blanka - Hocek, Michal
    C-H Imidation of 7-Deazapurines.
    ACS Omega. Roč. 3, č. 4 (2018), s. 4674-4678. ISSN 2470-1343. E-ISSN 2470-1343
    R&D Projects: GA ČR(CZ) GA16-00178S; GA MŠMT(CZ) LO1304
    Grant - others:AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : cross-coupling reactions * pyrimidine nucleosides * bond functionalization
    OECD category: Organic chemistry
    Impact factor: 2.584, year: 2018
    https://pubs.acs.org/doi/10.1021/acsomega.8b00520
    Permanent Link: http://hdl.handle.net/11104/0285280
     
     
  5. 5.
    0480866 - ÚOCHB 2018 RIV US eng J - Journal Article
    Perlíková, Pavla - Hocek, Michal
    Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides.
    Medicinal Research Reviews. Roč. 37, č. 6 (2017), s. 1429-1460. ISSN 0198-6325. E-ISSN 1098-1128
    R&D Projects: GA ČR(CZ) GA16-00178S
    Grant - others:AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : antivirals * cytostatics * deazapurines * nucleosides * nucleotides
    OECD category: Organic chemistry
    Impact factor: 8.290, year: 2017
    http://onlinelibrary.wiley.com/doi/10.1002/med.21465/full
    Permanent Link: http://hdl.handle.net/11104/0276543
    FileDownloadSizeCommentaryVersionAccess
    0480866.pdf31.3 MBPublisher’s postprintopen-access
     
     
  6. 6.
    0480257 - ÚOCHB 2018 RIV DE eng J - Journal Article
    Sabat, Nazarii - Smolen, Sabina - Nauš, Petr - Perlíková, Pavla - Cebová, M. - Poštová Slavětínská, Lenka - Hocek, Michal
    Synthesis of 2,6-Substituted 7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted 5-(Het)aryl-pyrrolo[2,3-d]pyrimidines).
    Synthesis. Roč. 49, č. 20 (2017), s. 4623-4650. ISSN 0039-7881. E-ISSN 1437-210X
    R&D Projects: GA ČR(CZ) GA16-00178S; GA MZd(CZ) NV15-31984A
    Grant - others:AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : deazapurines * pyrrolo[2,3-d]pyrimidines * nucleobases * Suzuki-Miyaura cross-coupling * deprotection * demethylation
    OECD category: Organic chemistry
    Impact factor: 2.722, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0276103
     
     
  7. 7.
    0480133 - ÚOCHB 2018 RIV GB eng J - Journal Article
    Konč, Juraj - Tichý, Michal - Pohl, Radek - Hodek, Jan - Džubák, P. - Hajdúch, M. - Hocek, Michal
    Sugar modified pyrimido[4,5-b] indole nucleosides: synthesis and antiviral activity.
    MedChemComm. Roč. 8, č. 9 (2017), s. 1856-1862. ISSN 2040-2503. E-ISSN 2040-2511
    R&D Projects: GA ČR(CZ) GA16-00178S
    Grant - others:AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : hepatitis C virus * modified derivatives * ribonucleosides
    OECD category: Organic chemistry
    Impact factor: 2.342, year: 2017
    http://pubs.rsc.org/en/content/articlehtml/2017/md/c7md00319f
    Permanent Link: http://hdl.handle.net/11104/0276042
     
     
  8. 8.
    0475217 - ÚOCHB 2018 RIV US eng J - Journal Article
    Tichý, Michal - Smolen, Sabina - Tloušťová, Eva - Pohl, Radek - Oždian, T. - Hejtmánková, K. - Lišková, B. - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
    Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.
    Journal of Medicinal Chemistry. Roč. 60, č. 6 (2017), s. 2411-2424. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304
    Institutional support: RVO:61388963
    Keywords : adenosine kinase inhibitors * cross-coupling reactions * cytotoxic nucleoside analogs
    OECD category: Organic chemistry
    Impact factor: 6.253, year: 2017
    http://pubs.acs.org/doi/full/10.1021/acs.jmedchem.6b01766
    Permanent Link: http://hdl.handle.net/11104/0272060
    FileDownloadSizeCommentaryVersionAccess
    0475217.pdf51.1 MBPublisher’s postprintopen-access
     
     
  9. 9.
    0475194 - ÚOCHB 2018 RIV DE eng J - Journal Article
    Downey, Alan Michael - Pohl, Radek - Roithová, J. - Hocek, Michal
    Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism.
    Chemistry - A European Journal. Roč. 23, č. 16 (2017), s. 3910-3917. ISSN 0947-6539. E-ISSN 1521-3765
    R&D Projects: GA TA ČR(CZ) TE01020028; GA ČR(CZ) GA16-00178S
    Institutional support: RVO:61388963
    Keywords : epoxides * glycosylation * nucleosides * riboses * synthesis design
    OECD category: Organic chemistry
    Impact factor: 5.160, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0272048
     
     
  10. 10.
    0466099 - ÚOCHB 2017 RIV US eng J - Journal Article
    Sabat, Nazarii - Poštová Slavětínská, Lenka - Klepetářová, Blanka - Hocek, Michal
    C-H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7-and 9-Deazapurine-8-phosphonate Derivatives.
    Journal of Organic Chemistry. Roč. 81, č. 19 (2016), s. 9507-9514. ISSN 0022-3263. E-ISSN 1520-6904
    R&D Projects: GA ČR(CZ) GA16-00178S; GA MŠMT(CZ) LO1304
    Institutional support: RVO:61388963
    Keywords : cross-coupling reactions * acyclic nucleoside phosphonates * biological activity
    Subject RIV: CC - Organic Chemistry
    Impact factor: 4.849, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0264499
     
     

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