Search results

  1. 1.
    0574116 - ÚEM 2024 RIV US eng J - Journal Article
    Kortus, Štěpán - Řeháková, Kristýna - Klíma, Martin - Kolcheva, Marharyta - Ladislav, Marek - Langore, Emily - Baráčková, Petra - Netolický, Jakub - Misiachna, Anna - Hemelíková, Katarína - Humpolíčková, Jana - Chalupská, Dominika - Šilhán, Jan - Kaniaková, Martina - Hrčka Krausová, Barbora - Bouřa, Evžen - Zápotocký, Martin - Horák, Martin
    Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes.
    Journal of Neuroscience. Roč. 43, č. 26 (2023), s. 4755-4774. ISSN 0270-6474. E-ISSN 1529-2401
    R&D Projects: GA ČR(CZ) GA20-12420S; GA MŠMT(CZ) LX22NPO5107
    Research Infrastructure: Czech-BioImaging III - 90250; Czech-BioImaging II - 90129
    Institutional support: RVO:68378041 ; RVO:61388963 ; RVO:67985823
    Keywords : GluN subunit * excitatory synapse * glutamate receptor * lateral diffusion * live microscopy * mammalian neuron
    OECD category: Neurosciences (including psychophysiology; Biochemistry and molecular biology (UOCHB-X); Biochemistry and molecular biology (FGU-C)
    Impact factor: 5.3, year: 2022
    Method of publishing: Open access
    https://www.jneurosci.org/content/43/26/4755
    Permanent Link: https://hdl.handle.net/11104/0344475
    FileDownloadSizeCommentaryVersionAccess
    Kortus 2023.pdf44.6 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0570624 - ÚEM 2024 RIV GB eng J - Journal Article
    Kolcheva, Marharyta - Ladislav, Marek - Netolický, Jakub - Kortus, Štěpán - Řeháková, Kristýna - Hrčka Krausová, Barbora - Hemeliková, Katarina - Misiachna, Anna - Kádková, Anna - Klíma, M. - Chalupská, D. - Horák, Martin
    The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors.
    Neuropharmacology. Roč. 222, jan. (2023), č. článku 109297. ISSN 0028-3908. E-ISSN 1873-7064
    R&D Projects: GA MŠMT(CZ) LX22NPO5107; GA ČR(CZ) GA20-12420S
    Institutional support: RVO:68378041
    Keywords : glutamate receptor * hippocampal neuron * neurodegeneration * ion channel * ketamine * memantine
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 4.7, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1016/j.neuropharm.2022.109297
    Permanent Link: https://hdl.handle.net/11104/0341931
     
    Review DownloadSizeCommentaryVersionAccess
    Kolcheva 2023.pdf87.8 MBPublisher’s postprintopen-access
     
  3. 3.
    0551558 - ÚEM 2022 RIV FR eng J - Journal Article
    Gorecki, L. - Misiachna, Anna - Damborský, J. - Doležal, R. - Korábečný, J. - Čejková, L. - Hakenová, K. - Chvojková, M. - Zdarová Karasová, J. - Prchal, L. - Novák, M. - Kolcheva, Marharyta - Kortus, Štěpán - Valeš, K. - Horák, Martin - Soukup, O.
    Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-D-Aspartate receptors.
    European Journal of Medicinal Chemistry. Roč. 219, 5 july (2021), č. článku 113434. ISSN 0223-5234. E-ISSN 1768-3254
    R&D Projects: GA ČR(CZ) GA20-12047S; GA TA ČR(CZ) TO01000078
    Institutional support: RVO:68378041
    Keywords : QSAR * acetylcholinesterase * electrophysiology * glutamate receptor * ion channel * pharmacologyin vivo * tacrine
    OECD category: Medicinal chemistry
    Impact factor: 7.088, year: 2021
    Method of publishing: Open access
    https://doi.org/10.1016/j.ejmech.2021.113434
    Permanent Link: http://hdl.handle.net/11104/0326821
     
     
  4. 4.
    0541886 - ÚEM 2022 RIV NL eng J - Journal Article
    Kolcheva, Marharyta - Kortus, Štěpán - Hrčka Krausová, Barbora - Baráčková, Petra - Misiachna, Anna - Danačíková, Š. - Kaniaková, Martina - Hemelíková, Katarína - Hotovec, Matěj - Řeháková, Kristýna - Horák, Martin
    Specific pathogenic mutations in the M3 domain of the GluN1 subunit regulate the surface delivery and pharmacological sensitivity of NMDA receptors.
    Neuropharmacology. Roč. 189, may (2021), č. článku 108528. ISSN 0028-3908. E-ISSN 1873-7064
    R&D Projects: GA ČR(CZ) GA20-12420S; GA TA ČR(CZ) TO01000078
    Institutional support: RVO:68378041
    Keywords : electrophysiology * glutamate receptor * hippocampal neuron * ion channel * memantine * membrane domain
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 5.273, year: 2021
    Method of publishing: Limited access
    https://doi.org/10.1016/j.neuropharm.2021.108528
    Permanent Link: http://hdl.handle.net/11104/0323424
     
     
  5. 5.
    0541833 - ÚEM 2022 RIV CH eng J - Journal Article
    Konečný, J. - Misiachna, Anna - Hrabinová, M. - Pulkrábková, L. - Benková, M. - Prchal, L. - Kučera, T. - Kobrlová, T. - Finger, V. - Kolcheva, Marharyta - Kortus, Štěpán - Jun, D. - Valko, M. - Horák, Martin - Soukup, O. - Korábečný, J.
    Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
    Biomolecules. Roč. 11, č. 1 (2021), č. článku 3. E-ISSN 2218-273X
    R&D Projects: GA MZd(CZ) NU20-08-00296
    Research Infrastructure: e-INFRA CZ - 90140
    Institutional support: RVO:68378041
    Keywords : acetylcholinesterase * Alzheimer´s disease * butyrylcholinesterase * fluorene * in vitro * in silico * multi-target directed ligands * N-methyl-d-aspartate receptor
    OECD category: Pharmacology and pharmacy
    Impact factor: 6.064, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/2218-273X/11/1/3
    Permanent Link: http://hdl.handle.net/11104/0319349
     
     
  6. 6.
    0538934 - ÚEM 2021 RIV GB eng J - Journal Article
    Skřenková, Kristýna - Song, JM. - Kortus, Štěpán - Kolcheva, Marharyta - Netolický, Jakub - Hemelíková, Katarína - Kaniaková, Martina - Hrčka Krausová, Barbora - Kučera, T. - Korábečný, J. - Suh, Y. H. - Horák, Martin
    The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors.
    Scientific Reports. Roč. 10, č. 1 (2020), č. článku 18576. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA ČR(CZ) GA20-12420S; GA MZd(CZ) NU20-08-00296
    Institutional support: RVO:68378041
    Keywords : methyl-d-aspartate * glutamate receptors * surface expression
    OECD category: Pharmacology and pharmacy
    Impact factor: 4.380, year: 2020
    Method of publishing: Open access
    https://www.nature.com/articles/s41598-020-75646-w
    Permanent Link: http://hdl.handle.net/11104/0316668
     
     
  7. 7.
    0508277 - ÚEM 2020 RIV GB eng J - Journal Article
    Skřenková, Kristýna - Hemelíková, Katarína - Kolcheva, Marharyta - Kortus, Štěpán - Kaniaková, Martina - Hrčka Krausová, Barbora - Horák, Martin
    Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors.
    Scientific Reports. Roč. 9, aug. (2019), č. článku 12303. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA MŠMT(CZ) LM2015062
    Institutional support: RVO:68378041
    Keywords : methyl-d-aspartate * endoplasmic-reticulum * molecular determinants * synaptic plasticity
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 3.998, year: 2019
    Method of publishing: Open access
    https://www.nature.com/articles/s41598-019-48845-3
    Permanent Link: http://hdl.handle.net/11104/0299233
     
     
  8. 8.
    0459871 - ÚEM 2017 RIV DE eng J - Journal Article
    Kortus, Štěpán - Srinivasan, Chinnapaiyan - Forostyak, Oksana - Zápotocký, M. - Ueta, Y. - Syková, Eva - Chvátal, Alexandr - Verkhratsky, A. - Dayanithi, Govindan
    Sodium-calcium exchanger and R-type Ca2+ channels mediate spontaneous [Ca2+](i) oscillations in magnocellular neurones of the rat supraoptic nucleus.
    Cell Calcium. Roč. 59, č. 6 (2016), s. 289-298. ISSN 0143-4160. E-ISSN 1532-1991
    R&D Projects: GA ČR(CZ) GA14-34077S; GA ČR(CZ) GBP304/12/G069
    Institutional support: RVO:68378041
    Keywords : 1,4,5-Trisphosphate * Ca(2+) channel toxins * Ca(2+) clearance * Ca(2+) homeostasis
    Subject RIV: FH - Neurology
    Impact factor: 3.707, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0260034
     
     
  9. 9.
    0459870 - ÚEM 2017 RIV DE eng J - Journal Article
    Kortus, Štěpán - Srinivasan, Chinnapaiyan - Forostyak, Oksana - Ueta, Y. - Syková, Eva - Chvátal, Alexandr - Zápotocký, M. - Verkhratsky, A. - Dayanithi, Govindan
    Physiology of spontaneous [Ca2+](i) oscillations in the isolated vasopressin and oxytocin neurones of the rat supraoptic nucleus.
    Cell Calcium. Roč. 6, č. 59 (2016), s. 280-288. ISSN 0143-4160. E-ISSN 1532-1991
    R&D Projects: GA ČR(CZ) GA14-34077S; GA ČR(CZ) GBP304/12/G069
    Institutional support: RVO:68378041
    Keywords : Ca(2+) oscillations * electrical activity * enhanced green fluorescence protein * fluorescence spectrofluorimetry
    Subject RIV: FH - Neurology
    Impact factor: 3.707, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0260039
     
     
  10. 10.
    0459078 - ÚEM 2017 RIV DE eng J - Journal Article
    Forostyak, Oksana - Forostyak, Serhiy - Kortus, Štěpán - Syková, Eva - Verkhratsky, A. - Dayanithi, Govindan
    Physiology of Ca2+ signalling in stem cells of different origins and differentiation stages.
    Cell Calcium. Roč. 59, 2-3 (2016), s. 57-66. ISSN 0143-4160. E-ISSN 1532-1991
    R&D Projects: GA ČR(CZ) GAP304/11/2373; GA ČR(CZ) GA14-34077S; GA ČR(CZ) GBP304/12/G069
    Institutional support: RVO:68378041
    Keywords : Stem cells * Ca2+ channels * Ca2+ signalling * Spontaneous Ca2+ oscillations
    Subject RIV: FH - Neurology
    Impact factor: 3.707, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0259342
     
     


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