Search results

  1. 1.
    0557479 - ÚOCHB 2023 RIV SE eng J - Journal Article
    Tupec, Michal - Culka, Martin - Machara, Aleš - Macháček, Stanislav - Bím, Daniel - Svatoš, Aleš - Rulíšek, Lubomír - Pichová, Iva
    Understanding desaturation/hydroxylation activity of castor stearoyl Δ9-Desaturase through rational mutagenesis.
    Computational and Structural Biotechnology Journal. Roč. 20 (2022), s. 1378-1388. ISSN 2001-0370. E-ISSN 2001-0370
    R&D Projects: GA MŠk(CZ) LTAUSA19148; GA MŠk(CZ) LM2015064; GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : Δ9 desaturase * methane monooxygenase * reaction mechanism
    OECD category: Biochemistry and molecular biology
    Impact factor: 7.271, year: 2020
    Method of publishing: Open access
    https://doi.org/10.1016/j.csbj.2022.03.010
    Permanent Link: http://hdl.handle.net/11104/0331450
     
     
  2. 2.
    0556929 - ÚOCHB 2023 RIV SE eng J - Journal Article
    Tupec, Michal - Culka, Martin - Machara, Aleš - Macháček, Stanislav - Bím, Daniel - Svatoš, Aleš - Rulíšek, Lubomír - Pichová, Iva
    Understanding desaturation/hydroxylation activity of castor stearoyl Δ9-Desaturase through rational mutagenesis.
    Computational and Structural Biotechnology Journal. Roč. 20, January (2022), s. 1378-1388. ISSN 2001-0370. E-ISSN 2001-0370
    R&D Projects: GA MŠk(CZ) LTAUSA19148; GA MŠk(CZ) LM2015064; GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : Δ9 desaturase * methane monooxygenase * reaction mechanism * proton transfer * desaturation * hydroxylation
    OECD category: Physical chemistry
    Impact factor: 7.271, year: 2020
    Method of publishing: Open access
    https://doi.org/10.1016/j.csbj.2022.03.010
    Permanent Link: http://hdl.handle.net/11104/0331046
     
     
  3. 3.
    0546812 - BC 2022 RIV GB eng J - Journal Article
    Miláček, Matěj - Bittová, Lenka - Tůmová, Šárka - Lukšan, Ondřej - Hanus, Robert - Kyjaková, Pavlína - Machara, Aleš - Marek, Aleš - Jindra, Marek
    Binding of de novo synthesized radiolabeled juvenile hormone (JH III) by JH receptors from the Cuban subterranean termite Prorhinotermes simplex and the German cockroach Blattella germanica.
    Insect Biochemistry and Molecular Biology. Roč. 139, DEC 01 (2021), č. článku 103671. ISSN 0965-1748. E-ISSN 1879-0240
    R&D Projects: GA ČR(CZ) GX20-05151X; GA MŠk(CZ) LM2015064; GA MŠk(CZ) LM2018131
    Institutional support: RVO:60077344 ; RVO:61388963
    Keywords : juvenile hormone * methoprene-tolerant * hormone receptor
    OECD category: Biochemistry and molecular biology; Entomology (UOCHB-X)
    Impact factor: 4.714, year: 2020
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0965174821001545?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0326652
     
     
  4. 4.
    0544791 - ÚOCHB 2022 RIV FR eng J - Journal Article
    Šimková, Adéla - Ormsby, Tereza - Sidej, Natan - Poštová Slavětínská, Lenka - Brynda, Jiří - Beranová, Jana - Šácha, Pavel - Majer, Pavel - Konvalinka, Jan
    Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads.
    European Journal of Medicinal Chemistry. Roč. 224, Nov 15 (2021), č. článku 113717. ISSN 0223-5234. E-ISSN 1768-3254
    R&D Projects: GA ČR(CZ) GA19-10280S; GA MZd(CZ) NV15-31379A; GA MŠk(CZ) EF16_019/0000729; GA MŠk(CZ) LM2015064
    Institutional support: RVO:61388963
    Keywords : fibroblast activation protein * seprase * FAP inhibitor * serine protease inhibition * prolyl endopeptidase * α-Ketoamide inhibitor
    OECD category: Medicinal chemistry
    Impact factor: 6.514, year: 2020
    Method of publishing: Open access
    https://doi.org/10.1016/j.ejmech.2021.113717
    Permanent Link: http://hdl.handle.net/11104/0321598
     
     
  5. 5.
    0543164 - ÚOCHB 2022 RIV DE eng J - Journal Article
    Kugler, Michael - Nekvinda, Jan - Holub, Josef - El Anwar, Suzan - Das, V. - Šícha, Václav - Pospíšilová, Klára - Fábry, M. - Král, V. - Brynda, Jiří - Kašička, Václav - Hajdúch, M. - Řezáčová, Pavlína - Grüner, Bohumír
    Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds.
    Chembiochem. Roč. 22, č. 18 (2021), s. 2741-2761. ISSN 1439-4227. E-ISSN 1439-7633
    R&D Projects: GA ČR(CZ) GA18-27648S; GA TA ČR(CZ) TE01020028; GA MŠk(CZ) LM2015064
    Institutional support: RVO:61388963 ; RVO:61388980
    Keywords : carbonic anhydrase * carborane * cobalt bis(dicarbollide) * crystallography * enzyme inhibition * SAR studies
    OECD category: Organic chemistry; Inorganic and nuclear chemistry (UACH-T)
    Impact factor: 3.164, year: 2020
    Method of publishing: Limited access
    https://doi.org/10.1002/cbic.202100121
    Permanent Link: http://hdl.handle.net/11104/0320438
     
     
  6. 6.
    0541879 - ÚOCHB 2022 RIV US eng J - Journal Article
    Perlíková, Pavla - Krajczyk, Anna - Doleželová, Eva - Slapničková, Martina - Milisavljevič, Nemanja - Poštová Slavětínská, Lenka - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Zíková, Alena - Hocek, Michal
    Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides.
    ACS Infectious Diseases. Roč. 7, č. 4 (2021), s. 917-926. ISSN 2373-8227
    R&D Projects: GA MŠk(CZ) EF16_019/0000729; GA MŠk(CZ) EF16_019/0000759; GA ČR(CZ) GA19-08124S; GA ČR(CZ) GA19-07707S; GA MŠk(CZ) LM2015064
    Grant - others: AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963 ; RVO:60077344
    Keywords : nucleosides * antiparasitic activity * antitrypanosomal * cytotoxicity
    OECD category: Organic chemistry; Organic chemistry (BC-A)
    Impact factor: 5.084, year: 2020
    Method of publishing: Limited access
    https://doi.org/10.1021/acsinfecdis.1c00062
    Permanent Link: http://hdl.handle.net/11104/0319376
     
     
  7. 7.
    0539969 - ÚMCH 2022 RIV GB eng J - Journal Article
    Holubová, Monika - Lobaz, Volodymyr - Loukotová, Lenka - Rabyk, Mariia - Hromádková, Jiřina - Trhlíková, Olga - Pechrová, Zdislava - Groborz, Ondřej - Štěpánek, Petr - Hrubý, Martin
    Does polysaccharide glycogen behave as a promoter of amyloid fibril formation at physiologically relevant concentrations?
    Soft Matter. Roč. 17, č. 6 (2021), s. 1628-1641. ISSN 1744-683X. E-ISSN 1744-6848
    R&D Projects: GA MŠk(CZ) LM2015064; GA ČR(CZ) GA19-01602S; GA ČR(CZ) GA18-07983S
    Institutional support: RVO:61389013
    Keywords : glycogen * amyloid fibrils * chemical modification of polysacchaide
    OECD category: Polymer science
    Impact factor: 3.679, year: 2020
    Method of publishing: Limited access
    https://pubs.rsc.org/en/content/articlelanding/2021/SM/D0SM01884H#!divAbstract
    Permanent Link: http://hdl.handle.net/11104/0318611
     
     
  8. 8.
    0539965 - ÚMCH 2022 RIV GB eng J - Journal Article
    Holubová, Monika - Lobaz, Volodymyr - Loukotová, Lenka - Rabyk, Mariia - Hromádková, Jiřina - Trhlíková, Olga - Pechrová, Zdislava - Groborz, Ondřej - Štěpánek, Petr - Hrubý, Martin
    Chemically modified glycogens: how they influence formation of amyloid fibrils?
    Soft Matter. Roč. 17, č. 6 (2021), s. 1614-1627. ISSN 1744-683X. E-ISSN 1744-6848
    R&D Projects: GA MŠk(CZ) LM2015064; GA ČR(CZ) GA19-01602S; GA ČR(CZ) GA18-07983S
    Institutional support: RVO:61389013
    Keywords : amyloid fibrils * glycogen * modification of glycogen
    OECD category: Polymer science
    Impact factor: 3.679, year: 2020
    Method of publishing: Limited access
    https://pubs.rsc.org/en/content/articlelanding/2021/SM/D0SM01829E#!divAbstract
    Permanent Link: http://hdl.handle.net/11104/0318614
     
     
  9. 9.
    0537275 - ÚEM 2021 RIV US eng J - Journal Article
    Čejka, Čestmír - Kössl, Jan - Holáň, Vladimír - Zhang, J.H. - Čejková, Jitka
    An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress.
    Oxidative Medicine and Cellular Longevity. Roč. 2020, č. 2020 (2020), č. článku 7435260. ISSN 1942-0900. E-ISSN 1942-0994
    R&D Projects: GA MŠk(CZ) LM2015064; GA MŠk(CZ) LO1309; GA MŠk(CZ) LO1508
    Institutional support: RVO:68378041
    Keywords : rabbit cornea * nitric-oxide * saline
    OECD category: Cell biology
    Impact factor: 6.543, year: 2020
    Method of publishing: Open access
    https://www.hindawi.com/journals/omcl/2020/7435260/
    Permanent Link: http://hdl.handle.net/11104/0317009
     
     
  10. 10.
    0536679 - ÚMCH 2021 RIV US eng J - Journal Article
    Švec, Pavel - Nový, Z. - Kučka, Jan - Petřík, M. - Sedláček, Ondřej - Kuchař, M. - Lišková, B. - Medvedíková, M. - Kolouchová, Kristýna - Groborz, Ondřej - Loukotová, Lenka - Konefal, Rafal - Hajdúch, M. - Hrubý, Martin
    Iodinated choline transport-targeted tracers.
    Journal of Medicinal Chemistry. Roč. 63, č. 24 (2020), s. 15960-15978. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA ČR(CZ) GA19-01602S; GA MZd(CZ) NV16-30544A; GA MŠk(CZ) LM2015064
    Institutional support: RVO:61389013
    Keywords : choline transport * radioiodination * fluorocholine
    OECD category: Polymer science
    Impact factor: 7.446, year: 2020
    Method of publishing: Limited access
    https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01710
    Permanent Link: http://hdl.handle.net/11104/0315705