Search results
- 1.0556929 - ÚOCHB 2023 RIV SE eng J - Journal Article
Tupec, Michal - Culka, Martin - Machara, Aleš - Macháček, Stanislav - Bím, Daniel - Svatoš, Aleš - Rulíšek, Lubomír - Pichová, Iva
Understanding desaturation/hydroxylation activity of castor stearoyl Δ9-Desaturase through rational mutagenesis.
Computational and Structural Biotechnology Journal. Roč. 20, March (2022), s. 1378-1388. ISSN 2001-0370. E-ISSN 2001-0370
R&D Projects: GA MŠk(CZ) LTAUSA19148; GA MŠk(CZ) LM2015064; GA MŠk(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : Δ9 desaturase * methane monooxygenase * reaction mechanism * proton transfer * desaturation * hydroxylation
OECD category: Biochemistry and molecular biology
Impact factor: 6.155, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.csbj.2022.03.010
Permanent Link: http://hdl.handle.net/11104/0331046
- 2.0546812 - BC 2022 RIV GB eng J - Journal Article
Miláček, Matěj - Bittová, Lenka - Tůmová, Šárka - Lukšan, Ondřej - Hanus, Robert - Kyjaková, Pavlína - Machara, Aleš - Marek, Aleš - Jindra, Marek
Binding of de novo synthesized radiolabeled juvenile hormone (JH III) by JH receptors from the Cuban subterranean termite Prorhinotermes simplex and the German cockroach Blattella germanica.
Insect Biochemistry and Molecular Biology. Roč. 139, DEC 01 (2021), č. článku 103671. ISSN 0965-1748. E-ISSN 1879-0240
R&D Projects: GA ČR(CZ) GX20-05151X; GA MŠk(CZ) LM2015064; GA MŠk(CZ) LM2018131
Institutional support: RVO:60077344 ; RVO:61388963
Keywords : juvenile hormone * methoprene-tolerant * hormone receptor
OECD category: Biochemistry and molecular biology; Entomology (UOCHB-X)
Impact factor: 4.421, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0965174821001545?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0326652
- 3.0544791 - ÚOCHB 2022 RIV FR eng J - Journal Article
Šimková, Adéla - Ormsby, Tereza - Sidej, Natan - Poštová Slavětínská, Lenka - Brynda, Jiří - Beranová, Jana - Šácha, Pavel - Majer, Pavel - Konvalinka, Jan
Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads.
European Journal of Medicinal Chemistry. Roč. 224, Nov 15 (2021), č. článku 113717. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA19-10280S; GA MZd(CZ) NV15-31379A; GA MŠk(CZ) EF16_019/0000729; GA MŠk(CZ) LM2015064
Institutional support: RVO:61388963
Keywords : fibroblast activation protein * seprase * FAP inhibitor * serine protease inhibition * prolyl endopeptidase * α-Ketoamide inhibitor
OECD category: Medicinal chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2021.113717
Permanent Link: http://hdl.handle.net/11104/0321598
- 4.0543164 - ÚOCHB 2022 RIV DE eng J - Journal Article
Kugler, Michael - Nekvinda, Jan - Holub, Josef - El Anwar, Suzan - Das, V. - Šícha, Václav - Pospíšilová, Klára - Fábry, M. - Král, V. - Brynda, Jiří - Kašička, Václav - Hajdúch, M. - Řezáčová, Pavlína - Grüner, Bohumír
Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds.
Chembiochem. Roč. 22, č. 18 (2021), s. 2741-2761. ISSN 1439-4227. E-ISSN 1439-7633
R&D Projects: GA ČR(CZ) GA18-27648S; GA TA ČR(CZ) TE01020028; GA MŠk(CZ) LM2015064
Institutional support: RVO:61388963 ; RVO:61388980
Keywords : carbonic anhydrase * carborane * cobalt bis(dicarbollide) * crystallography * enzyme inhibition * SAR studies
OECD category: Organic chemistry; Inorganic and nuclear chemistry (UACH-T)
Impact factor: 3.468, year: 2021
Method of publishing: Limited access
https://doi.org/10.1002/cbic.202100121
Permanent Link: http://hdl.handle.net/11104/0320438
- 5.0541879 - ÚOCHB 2022 RIV US eng J - Journal Article
Perlíková, Pavla - Krajczyk, Anna - Doleželová, Eva - Slapničková, Martina - Milisavljevič, Nemanja - Poštová Slavětínská, Lenka - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Zíková, Alena - Hocek, Michal
Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides.
ACS Infectious Diseases. Roč. 7, č. 4 (2021), s. 917-926. ISSN 2373-8227
R&D Projects: GA MŠk(CZ) EF16_019/0000729; GA MŠk(CZ) EF16_019/0000759; GA ČR(CZ) GA19-08124S; GA ČR(CZ) GA19-07707S; GA MŠk(CZ) LM2015064
Grant - others: AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : nucleosides * antiparasitic activity * antitrypanosomal * cytotoxicity
OECD category: Organic chemistry; Organic chemistry (BC-A)
Impact factor: 5.578, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.1c00062
Permanent Link: http://hdl.handle.net/11104/0319376
- 6.0539969 - ÚMCH 2022 RIV GB eng J - Journal Article
Holubová, Monika - Lobaz, Volodymyr - Loukotová, Lenka - Rabyk, Mariia - Hromádková, Jiřina - Trhlíková, Olga - Pechrová, Zdislava - Groborz, Ondřej - Štěpánek, Petr - Hrubý, Martin
Does polysaccharide glycogen behave as a promoter of amyloid fibril formation at physiologically relevant concentrations?
Soft Matter. Roč. 17, č. 6 (2021), s. 1628-1641. ISSN 1744-683X. E-ISSN 1744-6848
R&D Projects: GA MŠk(CZ) LM2015064; GA ČR(CZ) GA19-01602S; GA ČR(CZ) GA18-07983S
Institutional support: RVO:61389013
Keywords : glycogen * amyloid fibrils * chemical modification of polysacchaide
OECD category: Polymer science
Impact factor: 4.046, year: 2021
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2021/SM/D0SM01884H#!divAbstract
Permanent Link: http://hdl.handle.net/11104/0318611
- 7.0539965 - ÚMCH 2022 RIV GB eng J - Journal Article
Holubová, Monika - Lobaz, Volodymyr - Loukotová, Lenka - Rabyk, Mariia - Hromádková, Jiřina - Trhlíková, Olga - Pechrová, Zdislava - Groborz, Ondřej - Štěpánek, Petr - Hrubý, Martin
Chemically modified glycogens: how they influence formation of amyloid fibrils?
Soft Matter. Roč. 17, č. 6 (2021), s. 1614-1627. ISSN 1744-683X. E-ISSN 1744-6848
R&D Projects: GA MŠk(CZ) LM2015064; GA ČR(CZ) GA19-01602S; GA ČR(CZ) GA18-07983S
Institutional support: RVO:61389013
Keywords : amyloid fibrils * glycogen * modification of glycogen
OECD category: Polymer science
Impact factor: 4.046, year: 2021
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2021/SM/D0SM01829E#!divAbstract
Permanent Link: http://hdl.handle.net/11104/0318614
- 8.0536679 - ÚMCH 2021 RIV US eng J - Journal Article
Švec, Pavel - Nový, Z. - Kučka, Jan - Petřík, M. - Sedláček, Ondřej - Kuchař, M. - Lišková, B. - Medvedíková, M. - Kolouchová, Kristýna - Groborz, Ondřej - Loukotová, Lenka - Konefal, Rafal - Hajdúch, M. - Hrubý, Martin
Iodinated choline transport-targeted tracers.
Journal of Medicinal Chemistry. Roč. 63, č. 24 (2020), s. 15960-15978. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA19-01602S; GA MZd(CZ) NV16-30544A; GA MŠk(CZ) LM2015064
Institutional support: RVO:61389013
Keywords : choline transport * radioiodination * fluorocholine
OECD category: Polymer science
Impact factor: 7.446, year: 2020
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01710
Permanent Link: http://hdl.handle.net/11104/0315705
- 9.0534197 - ÚOCHB 2021 RIV US eng J - Journal Article
Veselovská, Lucia - Pohl, Radek - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9H-Pyrido[2′,3′:4,5]- and Pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidines.
ACS Omega. Roč. 5, č. 40 (2020), s. 26278-26286. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA ČR(CZ) GA19-08124S; GA MŠk(CZ) LM2015064
Grant - others: AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : Thymidylate synthase inhibitors * receptor tyrosine kinase * biological activity
OECD category: Organic chemistry
Impact factor: 3.512, year: 2020
Method of publishing: Open access
https://doi.org/10.1021/acsomega.0c04302
Permanent Link: http://hdl.handle.net/11104/0312441
- 10.0532766 - ÚOCHB 2021 RIV DE eng J - Journal Article
Veselovská, Lucia - Kudlová, N. - Gurská, S. - Lišková, B. - Medvedíková, M. - Hodek, Ondřej - Tloušťová, Eva - Milisavljevič, Nemanja - Tichý, Michal - Perlíková, Pavla - Mertlíková-Kaiserová, Helena - Trylčová, Jana - Pohl, Radek - Klepetářová, Blanka - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides.
Chemistry - A European Journal. Roč. 26, č. 57 (2020), s. 13002-13015. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠk(CZ) LM2015064
Grant - others: AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : antitumor agents * antiviral agents * drug discovery * phosphorylation * ribonucleosides
OECD category: Organic chemistry
Impact factor: 5.236, year: 2020
Method of publishing: Limited access
https://doi.org/10.1002/chem.202001124
Permanent Link: http://hdl.handle.net/11104/0311179