Search results
- 1.0509605 - ÚOCHB 2020 RIV US eng J - Journal Article
Walle, L. V. - Stowe, I. B. - Šácha, Pavel - Lee, B. L. - Demon, D. - Fossoul, A. - Van Hauwermeiren, F. - Saavedra, P. H. V. - Šimon, Petr - Šubr, Vladimír - Kostka, Libor - Stivala, C. E. - Pham, V. C. - Staben, S. T. - Yamazoe, S. - Konvalinka, Jan - Kayagaki, N. - Lamkanfi, M.
MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
PLOS Biology. Roč. 17, č. 9 (2019), č. článku e3000354. ISSN 1544-9173. E-ISSN 1545-7885
R&D Projects: GA ČR(CZ) GA16-02938S
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : activation * NLRC4 * phosphorylation
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 7.076, year: 2019 ; AIS: 3.989, rok: 2019
Method of publishing: Open access
Result website:
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000354DOI: https://doi.org/10.1371/journal.pbio.3000354
Permanent Link: http://hdl.handle.net/11104/0300298File Download Size Commentary Version Access 0509605.pdf 0 4.3 MB Publisher’s postprint open-access - 2.0505496 - ÚOCHB 2020 RIV US eng J - Journal Article
Pospíšilová, Klára - Knedlík, Tomáš - Šácha, Pavel - Kostka, Libor - Schimer, Jiří - Brynda, Jiří - Král, V. - Cígler, Petr - Navrátil, Václav - Etrych, Tomáš - Šubr, Vladimír - Kugler, Michael - Fábry, M. - Řezáčová, Pavlína - Konvalinka, Jan
Inhibitor-Polymer Conjugates as a Versatile Tool for Detection and Visualization of Cancer-Associated Carbonic Anhydrase Isoforms.
ACS Omega. Roč. 4, č. 4 (2019), s. 6746-6756. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT(CZ) LO1304; GA MŠMT LO1302; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT EF16_026/0008382
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : renal-cell carcinoma * molecule-drug conjugate * intrinsic marker
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 2.870, year: 2019 ; AIS: 0.573, rok: 2019
Method of publishing: Open access
Result website:
https://pubs.acs.org/doi/10.1021/acsomega.9b00596DOI: https://doi.org/10.1021/acsomega.9b00596
Permanent Link: http://hdl.handle.net/11104/0296982 - 3.0501452 - ÚOCHB 2020 RIV US eng J - Journal Article
Vorlová, Barbora - Sedlák, František - Kašpárek, Petr - Šrámková, Karolína - Malý, M. - Zámečník, J. - Šácha, Pavel - Konvalinka, Jan
A novel PSMA/GCPII-deficient mouse model shows enlarged seminal vesicles upon aging.
Prostate. Roč. 79, č. 2 (2019), s. 126-139. ISSN 0270-4137. E-ISSN 1097-0045
R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT LO1302; GA MŠMT(CZ) LM2015040
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : dilated seminal vesicles * Folh1 * glutamate carboxypeptidase II * knockout mice * prostate-specific membrane antigen
OECD category: Biochemistry and molecular biology
Impact factor: 3.279, year: 2019 ; AIS: 0.813, rok: 2019
Method of publishing: Limited access
Result website:
https://onlinelibrary.wiley.com/doi/abs/10.1002/pros.23717DOI: https://doi.org/10.1002/pros.23717
Permanent Link: http://hdl.handle.net/11104/0296267 - 4.0499970 - ÚOCHB 2019 RIV US eng J - Journal Article
Šimon, Petr - Knedlík, Tomáš - Blažková, Kristýna - Dvořáková, Petra - Březinová, Anna - Kostka, Libor - Šubr, Vladimír - Konvalinka, Jan - Šácha, Pavel
Identification of Protein Targets of Bioactive Small Molecules Using Randomly Photomodified Probes.
ACS Chemical Biology. Roč. 13, č. 12 (2018), s. 3333-3342. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT LO1302; GA MZd(CZ) NV15-31379A
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : glutamate carboxypeptidase II * inhibitor * design
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 4.374, year: 2018 ; AIS: 1.674, rok: 2018
DOI: https://doi.org/10.1021/acschembio.8b00791
Permanent Link: http://hdl.handle.net/11104/0292149 - 5.0492895 - ÚOCHB 2019 RIV US eng J - Journal Article
Neburková, Jitka - Sedlák, František - Žáčková Suchanová, J. - Kostka, Libor - Šácha, Pavel - Šubr, Vladimír - Etrych, Tomáš - Šimon, Petr - Bařinková, Jitka - Kryštůfek, Robin - Španielová, Hana - Forstová, J. - Konvalinka, Jan - Cígler, Petr
Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles.
Molecular Pharmaceutics. Roč. 15, č. 8 (2018), s. 2932-2945. ISSN 1543-8384. E-ISSN 1543-8392
R&D Projects: GA ČR(CZ) GA16-16336S; GA ČR(CZ) GA16-02938S; GA MŠMT LO1302
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : GCPII * PSMA * inhibitor * click chemistry * targeting * cell * nanodiamond
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 4.396, year: 2018 ; AIS: 0.992, rok: 2018
DOI: https://doi.org/10.1021/acs.molpharmaceut.7b00889
Permanent Link: http://hdl.handle.net/11104/0286398 - 6.0492495 - ÚOCHB 2019 RIV NL eng J - Journal Article
Chaloupková, Z. - Balzerová, A. - Bařinková, J. - Medříková, Z. - Šácha, Pavel - Beneš, P. - Ranc, V. - Konvalinka, J. - Zbořil, R.
Label-free determination of prostate specific membrane antigen in human whole blood at nanomolar levels by magnetically assisted surface enhanced Raman spectroscopy.
Analytica Chimica Acta. Roč. 997, Jan 2 (2018), s. 44-51. ISSN 0003-2670. E-ISSN 1873-4324
R&D Projects: GA MŠMT LO1302; GA MŠMT(CZ) LO1304; GA ČR(CZ) GA16-02938S
Institutional support: RVO:61388963
Keywords : Raman spectroscopy * nanocomposites * prostate cancer * GCPII * MA-SERS
OECD category: Biochemistry and molecular biology
Impact factor: 5.256, year: 2018 ; AIS: 0.994, rok: 2018
DOI: https://doi.org/10.1016/j.aca.2017.10.008
Permanent Link: http://hdl.handle.net/11104/0286008 - 7.0479478 - ÚOCHB 2018 RIV GB eng J - Journal Article
Knedlík, Tomáš - Vorlová, Barbora - Navrátil, Václav - Tykvart, Jan - Sedlák, František - Vaculín, Š. - Franěk, M. - Šácha, Pavel - Konvalinka, Jan
Mouse glutamate carboxypeptidaseII (GCPII) has a similar enzyme activity and inhibition profile but a different tissue distribution to human GCPII.
FEBS Open Bio. Roč. 7, č. 9 (2017), s. 1362-1378. ISSN 2211-5463. E-ISSN 2211-5463
R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : glutamate carboxypeptidase II * mouse animal model * neuronal disorders * prostate cancer * prostate-specific membrane antigen
OECD category: Biochemistry and molecular biology
Impact factor: 1.782, year: 2017 ; AIS: 0.568, rok: 2017
Result website:
http://onlinelibrary.wiley.com/doi/10.1002/2211-5463.12276/fullDOI: https://doi.org/10.1002/2211-5463.12276
Permanent Link: http://hdl.handle.net/11104/0275468