Search results
- 1.0604507 - ÚMG 2025 RIV US eng J - Journal Article
Rico-Llanos, G. - Špoutil, František - Bláhová, E. - Koudelka, A. - Procházková, Michaela - Czyrek, A. - Fafílek, Bohumil - Procházka, Jan - Lopez, M. G. - Křivánek, J. - Sedláček, Radislav - Krakow, D. - Nonaka, Y. - Nakamura, Y. - Krejčí, Pavel
Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy.
Journal of Bone and Mineral Research. Roč. 39, č. 12 (2024), s. 1783-1792. ISSN 0884-0431. E-ISSN 1523-4681
R&D Projects: GA MŠMT LX22NPO5102; GA MZd NU23-10-00550; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT(CZ) LM2023050; GA MŠMT EF18_046/0015861
Institutional support: RVO:68378050 ; RVO:67985904
Keywords : growth * receptor * ossification * activation * closure * rescues * achondroplasia * Fgfr3 * fibroblast growth factor * treatment * postnatal * infigratinib
OECD category: Developmental biology
Impact factor: 5.1, year: 2023 ; AIS: 1.847, rok: 2023
Method of publishing: Open access
Result website:
https://academic.oup.com/jbmr/article/39/12/1783/7826674?login=falseDOI: https://doi.org/10.1093/jbmr/zjae173
Permanent Link: https://hdl.handle.net/11104/0361937File Download Size Commentary Version Access zjae173.pdf 1 2.5 MB Publisher’s postprint open-access - 2.0601094 - ÚMG 2025 RIV CH eng J - Journal Article
Augusto Vale, Ana Matilde - Procházka, Jan - Sedláček, Radislav
Towards a Cure for Diamond-Blackfan Anemia: Views on Gene Therapy.
Cells. Roč. 13, č. 11 (2024), č. článku 920. ISSN 2073-4409. E-ISSN 2073-4409
R&D Projects: GA MŠMT LM2023036
EU Projects: European Commission(DK) 101072427 - GetRadi
Grant - others:AV ČR(CZ) StrategieAV21/29
Program: StrategieAV
Institutional support: RVO:68378050
Keywords : bone-marrow failure * lentiviral vectors * mouse model * rps19 * cell * challenges * deficiency * Diamond-Blackfan anemia * ribosomopathy * ribosomal protein genes * rare genetic disorder * hematopoietic stem cell transplantation * gene therapy * lentiviral vector * non-integrating lentiviral vector * CRISPR/Cas9
OECD category: Biochemistry and molecular biology
Impact factor: 5.1, year: 2023 ; AIS: 1.337, rok: 2023
Method of publishing: Open access
Result website:
https://www.mdpi.com/2073-4409/13/11/920DOI: https://doi.org/10.3390/cells13110920
Permanent Link: https://hdl.handle.net/11104/0358307 - 3.0601093 - ÚMG 2025 RIV US eng J - Journal Article
Janušová, Šárka - Paprčková, Darina - Michálik, Juraj - Uleri, Valeria - Drobek, Aleš - Šályová, Eva - Chorfi, M.S. - Neuwirth, Aleš - Andreyeva, Arina - Procházka, Jan - Sedláček, Radislav - Dráber, Peter - Štěpánek, Ondřej
ABIN1 is a negative regulator of effector functions in cytotoxic T cells.
Embo Reports. Roč. 25, č. 8 (2024), s. 3456-3485. ISSN 1469-221X. E-ISSN 1469-3178
R&D Projects: GA ČR GA22-18046S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT ED2.1.00/19.0395; GA MŠMT LM2023036; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LM2023050
EU Projects: European Commission(XE) 802878 - FunDiT
Institutional support: RVO:68378050
Keywords : nf-kappa-b * expression * kinase * cd8(+) * quantification * activation * enrichment * autophagy * signals * gamma * T Cells * Co-stimulation * Antigen Receptor * abin1 * p38
OECD category: Biochemistry and molecular biology
Impact factor: 6.5, year: 2023 ; AIS: 3.271, rok: 2023
Method of publishing: Limited access
Result website:
https://www.embopress.org/doi/full/10.1038/s44319-024-00179-6DOI: https://doi.org/10.1038/s44319-024-00179-6
Permanent Link: https://hdl.handle.net/11104/0358306File Download Size Commentary Version Access janusova-et-al-2024-abin1-is-a-negative-regulator-of-effector-functions-in-cytotoxic-t-cells.pdf 0 5.9 MB Publisher’s postprint open-access - 4.0601090 - ÚMG 2025 RIV US eng J - Journal Article
Buccheri, Valeria - Pasulka, Josef - Malík, Radek - Loubalová, Zuzana - Táborská, Eliška - Horvat, Filip - Kulmann, Marcos Iuri Roos - Jeníčková, Irena - Procházka, Jan - Sedláček, Radislav - Svoboda, Petr
Functional canonical RNAi in mice expressing a truncated Dicer isoform and long dsRNA.
Embo Reports. Roč. 25, č. 7 (2024), s. 2896-2913. ISSN 1469-221X. E-ISSN 1469-3178
R&D Projects: GA ČR GX20-03950X; GA MŠMT LO1419; GA MŠMT(CZ) LM2018126
Research Infrastructure: e-INFRA CZ II - 90254; ELIXIR CZ III - 90255
Institutional support: RVO:68378050
Keywords : double-stranded-rna * gene-expression * microrna biogenesis * mammalian-cells * mouse * interference * oocytes * potent * inhibition * mirtrons * Dicer * dsRNA * Mirtron * siRNA * pkr
OECD category: Biochemistry and molecular biology
Impact factor: 6.5, year: 2023 ; AIS: 3.271, rok: 2023
Method of publishing: Open access
Result website:
https://www.embopress.org/doi/full/10.1038/s44319-024-00148-zDOI: https://doi.org/10.1038/s44319-024-00148-z
Permanent Link: https://hdl.handle.net/11104/0358303 - 5.0599475 - FGÚ 2025 RIV US eng J - Journal Article
Candelas Serra, Miriam - Kuchtiak, Viktor - Kubik-Zahorodna, Agnieszka - Kysilov, Bohdan - Fili, Klevinda - Hrčka Krausová, Barbora - Abramová, Vera - Dobrovolski, Mark - Harant, K. - Božíková, Paulina - Černý, Jiří - Procházka, Jan - Kašpárek, Petr - Sedláček, Radislav - Balík, Aleš - Smejkalová, Tereza - Vyklický ml., Ladislav
Characterization of Mice Carrying a Neurodevelopmental Disease-Associated GluN2B(L825V) Variant.
Journal of Neuroscience. Roč. 44, č. 31 (2024), č. článku e2291232024. ISSN 0270-6474. E-ISSN 1529-2401
R&D Projects: GA ČR(CZ) GA23-04922S; GA MŠMT EF18_046/0015861; GA MŠMT(CZ) LQ1604
Research Infrastructure: CCP III - 90236
Institutional support: RVO:67985823 ; RVO:86652036 ; RVO:68378050
Keywords : autism spectrum disorder * GluN2B * mouse model * NMDA receptors * synaptic transmission
OECD category: Neurosciences (including psychophysiology; Neurosciences (including psychophysiology (BTO-N); Biochemistry and molecular biology (UMG-J)
Impact factor: 4.4, year: 2023 ; AIS: 2.222, rok: 2023
Result website:
https://doi.org/10.1523/JNEUROSCI.2291-23.2024DOI: https://doi.org/10.1523/JNEUROSCI.2291-23.2024
Permanent Link: https://hdl.handle.net/11104/0356903 - 6.0598321 - ÚMG 2025 RIV GB eng J - Journal Article
Zancolli, G. - von Reumont, B. M. - Anderluh, G. - Caliskan, F. - Chiusano, M. L. - Froehlich, J. - Hapeshi, E. - Hempel, B. - Ikonomopoulou, M. P. - Jungo, F. - Marchot, P. - de Farias, T. M. - Modica, M. V. - Moran, Y. - Nalbantsoy, A. - Procházka, Jan - Tarallo, A. - Tonello, F. - Vitorino, R. - Zammit, M. L. - Antunes, A.
Web of venom: exploration of big data resources in animal toxin research.
GigaScience. Roč. 13, Jul (2024), č. článku giae054. ISSN 2047-217X. E-ISSN 2047-217X
Institutional support: RVO:68378050
Keywords : mass-spectrometry data * peptide identification * high-accuracy * snake-venom * genome * transcriptome * evolution * insights * ontology * annotation * venom resources * toxin databases * machine learning * drug discovery * antivenom * proteomics * peptidomics * transcriptomics * genomics
OECD category: Biochemistry and molecular biology
Impact factor: 11.8, year: 2023 ; AIS: 4.08, rok: 2023
Method of publishing: Open access
Result website:
https://academic.oup.com/gigascience/article/doi/10.1093/gigascience/giae054/7753515?login=falseDOI: https://doi.org/10.1093/gigascience/giae054
Permanent Link: https://hdl.handle.net/11104/0356358 - 7.0597892 - ÚMG 2025 RIV US eng J - Journal Article
Sinigaglia, K. - Cherian, A. - Du, Q. - Lacovich, V. - Vukic, D. - Melicherová, J. - Linhartová, P. - Zerad, L. - Stejskal, S. - Malík, Radek - Procházka, Jan - Bondurand, N. - Sedláček, Radislav - O'Connell, M. A. - Keegan, L. P.
An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation.
Cell Reports. Roč. 43, č. 8 (2024), č. článku 114618. ISSN 2211-1247. E-ISSN 2211-1247
R&D Projects: GA MŠMT(CZ) LM2023050; GA MŠMT(CZ) LM2018126
Grant - others:Ministerstvo školství, mládeže a tělovýchovy - GA MŠk(CZ) LM2018140
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:68378050
Keywords : rna * recognition * dimerization * elf2-alpha
OECD category: Biochemistry and molecular biology
Impact factor: 7.5, year: 2023 ; AIS: 3.775, rok: 2023
Method of publishing: Open access
Result website:
https://www.sciencedirect.com/science/article/pii/S2211124724009689?via%3DihubDOI: https://doi.org/10.1016/j.celrep.2024.114618
Permanent Link: https://hdl.handle.net/11104/0356362 - 8.0597694 - ÚMG 2025 RIV US eng J - Journal Article
Aich, A. - Boshnakovska, A. - Witte, S. - Gall, T. - Unthan-Fechner, K. - Yousefi, R. - Chowdhury, A. - Dahal, D. - Methi, A. - Kaufmann, S. - Silbern, I. - Procházka, Jan - Nichtová, Zuzana - Pálková, Marcela - Raishbrook, Miles Joseph - Koubková, Gizela - Sedláček, Radislav - Troeder, S. E. - Zevnik, B. - Riedel, D. - Michanski, S. - Moebius, W. - Stroebel, P. - Luechtenborg, C. - Giavalisco, P. - Urlaub, H. - Fischer, A. - Bruegger, B. - Jakobs, S. - Rehling, P.
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver.
Nature Communications. Roč. 15, č. 1 (2024), č. článku 6914. ISSN 2041-1723. E-ISSN 2041-1723
R&D Projects: GA MŠMT LM2023036; GA MŠMT EF18_046/0015861
Institutional support: RVO:68378050
Keywords : mass-spectrometry * mutations * dna * fragments * platform * database * pathway * genes
OECD category: Biochemistry and molecular biology
Impact factor: 14.7, year: 2023 ; AIS: 5.656, rok: 2023
Method of publishing: Open access
Result website:
https://www.nature.com/articles/s41467-024-51109-yDOI: https://doi.org/10.1038/s41467-024-51109-y
Permanent Link: https://hdl.handle.net/11104/0361974 - 9.0587905 - ÚŽFG 2025 RIV GB eng J - Journal Article
Hampl, Marek - Jandová, Nela - Lusková, Denisa - Nováková, M. - Szotkowská, Tereza - Čada, Š. - Procházka, Jan - Kohoutek, J. - Buchtová, Marcela
Early embryogenesis in CHDFIDD mouse model reveals facial clefts and altered cranial neurogenesis.
Disease Models & Mechanisms. Roč. 17, č. 6 (2024), č. článku dmm050261. ISSN 1754-8403. E-ISSN 1754-8411
R&D Projects: GA ČR GA19-01205S; GA ČR GA22-02794S; GA MŠMT EF15_003/0000460; GA MŠMT LX22NPO5102
Institutional support: RVO:67985904 ; RVO:68378050
Keywords : craniofacial development * orofacial clefts * axons
OECD category: Cell biology
Impact factor: 4, year: 2023 ; AIS: 1.279, rok: 2023
Method of publishing: Open access
Result website:
https://journals.biologists.com/dmm/article/17/6/dmm050261/358081/Early-embryogenesis-in-CHDFIDD-mouse-model-revealsDOI: https://doi.org/10.1242/dmm.050261
Permanent Link: https://hdl.handle.net/11104/0354972 - 10.0587222 - ÚMG 2025 CH eng J - Journal Article
Augusto Vale, Ana Matilde - Procházka, Jan - Sedláček, Radislav
Towards a Cure for Diamond-Blackfan Anemia: Views on Gene Therapy.
Cells. Roč. 13, č. 11 (2024), č. článku 920. ISSN 2073-4409. E-ISSN 2073-4409
R&D Projects: GA MŠMT LM2023036
EU Projects: European Commission(DK) 101072427 - GetRadi
Grant - others:AV ČR(CZ) StrategieAV21/29
Program: StrategieAV
Institutional support: RVO:68378050
Keywords : bone-marrow failure * lentiviral vectors * mouse model * rps19 * cell * challenges * deficiency * Diamond-Blackfan anemia * ribosomopathy * ribosomal protein genes * rare genetic disorder * hematopoietic stem cell transplantation * gene therapy * lentiviral vector * non-integrating lentiviral vector * CRISPR/Cas9
OECD category: Biochemistry and molecular biology
Impact factor: 5.1, year: 2023 ; AIS: 1.337, rok: 2023
Method of publishing: Limited access
Result website:
https://www.mdpi.com/2073-4409/13/11/920DOI: https://doi.org/10.3390/cells13110920
Permanent Link: https://hdl.handle.net/11104/0354868