Search results
- 1.0544791 - ÚOCHB 2022 RIV FR eng J - Journal Article
Šimková, Adéla - Ormsby, Tereza - Sidej, Natan - Poštová Slavětínská, Lenka - Brynda, Jiří - Beranová, Jana - Šácha, Pavel - Majer, Pavel - Konvalinka, Jan
Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads.
European Journal of Medicinal Chemistry. Roč. 224, Nov 15 (2021), č. článku 113717. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA19-10280S; GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963
Keywords : fibroblast activation protein * seprase * FAP inhibitor * serine protease inhibition * prolyl endopeptidase * α-Ketoamide inhibitor
OECD category: Medicinal chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2021.113717
Permanent Link: http://hdl.handle.net/11104/0321598 - 2.0523934 - ÚOCHB 2021 RIV NL eng J - Journal Article
Šimková, Adéla - Bušek, P. - Šedo, A. - Konvalinka, Jan
Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications.
Biochimica Et Biophysica Acta-Proteins and Proteomics. Roč. 1868, č. 7 (2020), č. článku 140409. ISSN 1570-9639. E-ISSN 1878-1454
R&D Projects: GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) LM2015064; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : fibroblast activation protein * FAP inhibitors * FAP substrates * cancer tissue targeting * activity-based probes
OECD category: Biochemistry and molecular biology
Impact factor: 3.036, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S1570963920300546
Permanent Link: http://hdl.handle.net/11104/0308229 - 3.0499970 - ÚOCHB 2019 RIV US eng J - Journal Article
Šimon, Petr - Knedlík, Tomáš - Blažková, Kristýna - Dvořáková, Petra - Březinová, Anna - Kostka, Libor - Šubr, Vladimír - Konvalinka, Jan - Šácha, Pavel
Identification of Protein Targets of Bioactive Small Molecules Using Randomly Photomodified Probes.
ACS Chemical Biology. Roč. 13, č. 12 (2018), s. 3333-3342. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT LO1302; GA MZd(CZ) NV15-31379A
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : glutamate carboxypeptidase II * inhibitor * design
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 4.374, year: 2018
Permanent Link: http://hdl.handle.net/11104/0292149 - 4.0481818 - ÚOCHB 2018 RIV US eng J - Journal Article
Dvořáková, Petra - Bušek, P. - Knedlík, Tomáš - Schimer, Jiří - Etrych, Tomáš - Kostka, Libor - Stollinová Šromová, L. - Šubr, Vladimír - Šácha, Pavel - Šedo, A. - Konvalinka, Jan
Inhibitor-decorated Polymer Conjugates Targeting Fibroblast Activation Protein.
Journal of Medicinal Chemistry. Roč. 60, č. 20 (2017), s. 8385-8393. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) LM2015064; GA MŠMT LO1302
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : dipeptidyl peptidase IV * metastatic colorectal cancer * integral membrane protease
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 6.253, year: 2017
Permanent Link: http://hdl.handle.net/11104/0277469