Search results
- 1.0483897 - ÚOCHB 2018 RIV GB eng J - Journal Article
Dubánková, Anna - Humpolíčková, Jana - Klíma, Martin - Bouřa, Evžen
Negative charge and membrane-tethered viral 3B cooperate to recruit viral RNA dependent RNA polymerase 3D(pol).
Scientific Reports. Roč. 7, Dec 11 (2017), č. článku 17309. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR GJ15-21030Y
Institutional support: RVO:61388963
Keywords : 4-kinase III beta * in-vitro reconstitution * poliovirus protein 3AB
OECD category: Biochemistry and molecular biology
Impact factor: 4.122, year: 2017
https://www.nature.com/articles/s41598-017-17621-6
Permanent Link: http://hdl.handle.net/11104/0279061File Download Size Commentary Version Access 0483897.pdf 4 4.8 MB Publisher’s postprint open-access - 2.0459191 - ÚOCHB 2017 RIV GB eng J - Journal Article
Klíma, Martin - Tóth, D. J. - Hexnerová, Rozálie - Bäumlová, Adriana - Chalupská, Dominika - Tykvart, Jan - Řežábková, L. - Sengupta, N. - Man, Petr - Dubánková, Anna - Humpolíčková, Jana - Nencka, Radim - Veverka, Václav - Balla, T. - Bouřa, Evžen
Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein.
Scientific Reports. Roč. 6, Mar 24 (2016), č. článku 23641. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR GJ15-21030Y; GA MŠMT LO1302; GA MŠMT(CZ) LK11205; GA MŠMT(CZ) LO1304; GA MŠMT LO1509
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : 4-kinase III beta * phosphatidylinositol 4-kinases * endoplasmic reticulum
Subject RIV: CE - Biochemistry; EE - Microbiology, Virology (MBU-M)
Impact factor: 4.259, year: 2016
http://www.nature.com/articles/srep23641
Permanent Link: http://hdl.handle.net/11104/0259422File Download Size Commentary Version Access 0459191.pdf 5 5.4 MB Publisher’s postprint open-access - 3.0449209 - ÚOCHB 2016 RIV US eng J - Journal Article
Bouřa, Evžen - Nencka, Radim
Phosphatidylinositol 4-kinases: Function, structure, and inhibition.
Experimental Cell Research. Roč. 337, č. 2 (2015), s. 136-145. ISSN 0014-4827. E-ISSN 1090-2422
R&D Projects: GA ČR GJ15-21030Y; GA MŠMT LO1302; GA ČR GA15-09310S
EU Projects: European Commission(XE) 333916 - STARPI4K
Institutional support: RVO:61388963
Keywords : phosphatidylinositol 4-kinase * inhibitor * crystal structure * virus
Subject RIV: CC - Organic Chemistry
Impact factor: 3.378, year: 2015
Permanent Link: http://hdl.handle.net/11104/0250870 - 4.0446387 - ÚOCHB 2016 RIV DK eng J - Journal Article
Klíma, Martin - Bäumlová, Adriana - Chalupská, Dominika - Hřebabecký, Hubert - Dejmek, Milan - Nencka, Radim - Bouřa, Evžen
The high-resolution crystal structure of phosphatidylinositol 4-kinase II beta and the crystal structure of phosphatidylinositol 4-kinase II alpha containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design.
Acta Crystallographica Section D-Biological Crystallography. Roč. 71, č. 7 (2015), s. 1555-1563. ISSN 1399-0047. E-ISSN 2059-7983
R&D Projects: GA ČR GJ15-21030Y; GA ČR GA15-09310S; GA MŠMT LO1302
EU Projects: European Commission(XE) 333916 - STARPI4K
Institutional support: RVO:61388963
Keywords : phosphatidyl inositol * kinase * crystal structure * ATP * inhibitor
Subject RIV: CE - Biochemistry
Impact factor: 2.512, year: 2015
Permanent Link: http://hdl.handle.net/11104/0248456 - 5.0444785 - ÚOCHB 2016 RIV US eng J - Journal Article
Mejdrová, Ivana - Chalupská, Dominika - Kögler, Martin - Šála, Michal - Plačková, Pavla - Bäumlová, Adriana - Hřebabecký, Hubert - Procházková, Eliška - Dejmek, Milan - Guillon, Rémi - Strunin, Dmytro - Weber, Jan - Lee, G. - Birkuš, G. - Mertlíková-Kaiserová, Helena - Bouřa, Evžen - Nencka, Radim
Highly Selective Phosphatidylinositol 4-Kinase III beta Inhibitors and Structural Insight into Their Mode of Action.
Journal of Medicinal Chemistry. Roč. 58, č. 9 (2015), s. 3767-3793. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT LO1302; GA ČR GA15-09310S; GA ČR GJ15-21030Y
EU Projects: European Commission(XE) 333916 - STARPI4K
Institutional support: RVO:61388963
Keywords : phosphatidylinositol 4-kinase III beta * broad-spectrum antiviral agents * positive-sense RNA viruses
Subject RIV: CC - Organic Chemistry
Impact factor: 5.589, year: 2015
Permanent Link: http://hdl.handle.net/11104/0247293