Search results
- 1.0555591 - ÚMG 2022 RIV GB eng J - Journal Article
Škuta, Ctibor - Southan, C. - Bartůněk, Petr
Will the chemical probes please stand up?
RSC MEDICINAL CHEMISTRY. Roč. 12, č. 8 (2021), s. 1428-1441. E-ISSN 2632-8682
R&D Projects: GA MŠMT(CZ) LM2018130
Research Infrastructure: CZ-OPENSCREEN III - 90130
Institutional support: RVO:68378050
Keywords : interference compounds pains * concise guide * inhibitors * discovery * libraries * drugs
OECD category: Biochemistry and molecular biology
Impact factor: 3.470, year: 2021
Method of publishing: Open access
https://pubs.rsc.org/en/content/articlelanding/2021/MD/D1MD00138H
Permanent Link: http://hdl.handle.net/11104/0330055 - 2.0539814 - ÚMG 2021 RIV GB eng J - Journal Article
Škuta, Ctibor - Cortes-Ciriano, I. - Dehaen, W. - Kříž, P. - van Westen, G.J.P. - Tetko, I. V. - Bender, A. - Svozil, Daniel
QSAR-derived affinity fingerprints (part 1): fingerprint construction and modeling performance for similarity searching, bioactivity classification and scaffold hopping.
Journal of Cheminformatics. Roč. 12, č. 1 (2020), č. článku 39. ISSN 1758-2946. E-ISSN 1758-2946
Institutional support: RVO:68378050
Keywords : Affinity fingerprint * Biological fingerprint * qsar * Similarity searching * Bioactivity modeling * Scaffold hopping
OECD category: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Impact factor: 5.514, year: 2020
Method of publishing: Open access
https://jcheminf.biomedcentral.com/articles/10.1186/s13321-020-00443-6
Permanent Link: http://hdl.handle.net/11104/0317517 - 3.0538137 - ÚMG 2021 RIV GB eng J - Journal Article
Cortes-Ciriano, I. - Škuta, Ctibor - Bender, A. - Svozil, Daniel
QSAR-derived affinity fingerprints (part 2): modeling performance for potency prediction.
Journal of Cheminformatics. Roč. 12, č. 1 (2020), č. článku 41. ISSN 1758-2946. E-ISSN 1758-2946
R&D Projects: GA MŠMT LM2015063
Institutional support: RVO:68378050
Keywords : qsar * Affinity fingerprints * ChEMBL * Bioactivity modeling * Cytotoxicity * Drug sensitivity prediction * Drug sensitivity
OECD category: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Impact factor: 5.514, year: 2020
Method of publishing: Open access
https://jcheminf.biomedcentral.com/articles/10.1186/s13321-020-00444-5
Permanent Link: http://hdl.handle.net/11104/0315960 - 4.0502626 - ÚMG 2019 RIV CZ cze J - Journal Article
Škuta, Ctibor - Svozil, Daniel
QSAR – Modelování kvantitativních vztahů mezi strukturou a aktivitou chemických látek.
[QSAR – Modelling of Quantitative Relations between Structure and Activity of Chemical Compounds.]
Chemické listy. Roč. 111, č. 11 (2017), s. 747-753. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA MŠMT LO1220
Institutional support: RVO:68378050
Keywords : QSAR * biological activity modelling * data mining * virtual screening * applicability domain * conformal prediction
OECD category: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Impact factor: 0.260, year: 2017
Permanent Link: http://hdl.handle.net/11104/0294522 - 5.0502026 - ÚMG 2019 RIV US eng J - Journal Article
Oltová, Jana - Jindřich, Jindřich - Škuta, Ctibor - Svoboda, Ondřej - Machoňová, Olga - Bartůněk, Petr
Zebrabase: An Intuitive Tracking Solution for Aquatic Model Organisms.
Zebrafish. Roč. 15, č. 6 (2018), s. 642-647. ISSN 1545-8547. E-ISSN 1557-8542
R&D Projects: GA ČR GA16-21024S; GA MŠMT LO1419
Institutional support: RVO:68378050
Keywords : zebrafish * tracking * husbandry * facility database * Django * Python
OECD category: Biochemistry and molecular biology
Impact factor: 1.742, year: 2018
Permanent Link: http://hdl.handle.net/11104/0293979File Download Size Commentary Version Access Zebrafish_J_Oltova_2018.pdf 11 289.8 KB Publisher’s postprint require - 6.0495161 - ÚMG 2019 RIV CH eng J - Journal Article
Bruštíková, Kateřina - Sedlák, David - Kubíková, Jana - Škuta, Ctibor - Šolcová, Kateřina - Malík, Radek - Bartůněk, Petr - Svoboda, Petr
Cell-Based Reporter System for High-Throughput Screening of MicroRNA Pathway Inhibitors and Its Limitations.
Frontiers in genetics. Roč. 9, Únor (2018), č. článku 45. E-ISSN 1664-8021
R&D Projects: GA ČR GA13-29531S; GA MŠMT LO1220; GA MŠMT LM2015063
Institutional support: RVO:68378050
Keywords : miRNA * high-throughput screening * let-7 * miR-30 * Argonaute
OECD category: Cell biology
Impact factor: 3.517, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288172 - 7.0487037 - ÚMG 2018 RIV US eng J - Journal Article
Škuta, Ctibor - Popr, M. - Muller, Tomáš - Jindřich, Jindřich - Kahle, Michal - Sedlák, David - Svozil, Daniel - Bartůněk, Petr
Probes & Drugs portal: an interactive, open data resource for chemical biology.
Nature Methods. Roč. 14, č. 8 (2017), s. 758-759. ISSN 1548-7091. E-ISSN 1548-7105
R&D Projects: GA MŠMT LO1220
Institutional support: RVO:68378050
Keywords : bioactive compound, ,, * chemical probe * chemical biology * portal
OECD category: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Impact factor: 26.919, year: 2017
Permanent Link: http://hdl.handle.net/11104/0281725File Download Size Commentary Version Access Nature_Methods_C_Skuta_2017.pdf 4 981.7 KB Publisher’s postprint require - 8.0468176 - MBÚ 2017 RIV US eng J - Journal Article
Biedermann, David - Buchta, M. - Holečková, Veronika - Sedlák, David - Valentová, Kateřina - Cvačka, Josef - Bednárová, Lucie - Křenková, Alena - Kuzma, Marek - Škuta, Ctibor - Peikerová, Žaneta - Bartůněk, Petr - Křen, Vladimír
Silychristin: Skeletal Alterations and Biological Activities.
Journal of Natural Products. Roč. 79, č. 12 (2016), s. 3086-3092. ISSN 0163-3864. E-ISSN 1520-6025
R&D Projects: GA ČR(CZ) GA15-03037S; GA MZd(CZ) NV16-27317A; GA MŠMT LO1220; GA MŠMT LM2015063; GA MŠMT(CZ) LD15081
Institutional support: RVO:61388971 ; RVO:68378050 ; RVO:61388963
Keywords : Silychristin * skeletal alterations * biological activities
Subject RIV: CC - Organic Chemistry
Impact factor: 3.281, year: 2016
Permanent Link: http://hdl.handle.net/11104/0266155File Download Size Commentary Version Access 114_SilychristinSkeletalAlterationsAndBiologicalActivities.pdf 4 496.1 KB Publisher’s postprint require - 9.0441263 - ÚMG 2015 RIV GB eng J - Journal Article
Škuta, Ctibor - Bartůněk, Petr - Svozil, Daniel
InCHlib - interactive cluster heatmap for web applications.
Journal of Cheminformatics. Roč. 6, č. 44 (2014). ISSN 1758-2946. E-ISSN 1758-2946
R&D Projects: GA MŠMT LO1220
Institutional support: RVO:68378050
Keywords : Data clustering * Cluster heatmap * Scientific visualization * Web integration * Client-side scripting * JavaScript library * Big data * Exploration
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.547, year: 2014
Permanent Link: http://hdl.handle.net/11104/0244328File Download Size Commentary Version Access 0441263.pdf 12 1.5 MB Publisher’s postprint require