Search results
- 1.0575033 - ÚOCHB 2024 RIV US eng J - Journal Article
Koutná, Eliška - Lux, Vanda - Kouba, Tomáš - Škerlová, Jana - Nováček, J. - Srb, Pavel - Hexnerová, Rozálie - Šváchová, Hana - Kukačka, Zdeněk - Novák, Petr - Fábry, Milan - Poepsel, S. - Veverka, Václav
Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Research. Roč. 51, č. 18 (2023), s. 10011-10025. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR(CZ) GA22-03028S; GA ČR(CZ) GA22-27695S; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LO1304
Research Infrastructure: CIISB II - 90127; CIISB III - 90242
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : PWWP domain * recombinant histones * structural basis
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (MBU-M)
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/nar/gkad674
Permanent Link: https://hdl.handle.net/11104/0344870 - 2.0551742 - ÚEB 2022 RIV US eng J - Journal Article
Zálešák, F. - Kováč, O. - Lachetová, I. - Šťastná, N. - Pospíšil, Jiří
Unified Approach to Benzo[d]thiazol-2-yl-Sulfonamides.
WASHINGTONSEP 3 2021: AMER CHEMICAL SOC, 2021. Journal of Organic Chemistry. Roč. 86, č. 17 (2021), s. 11291-11309. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LO1204; GA MŠMT(CZ) EF16_019/0000738
Institutional support: RVO:61389030
Keywords : factor xa inhibitors * convenient preparation * sulfur-dioxide * sulfonamides * amines * amination * sulfonyl * sulfenamides * design * access
OECD category: Biochemistry and molecular biology
Impact factor: 4.198, year: 2021
Method of publishing: Open access
http://doi.org/10.1021/acs.joc.1c00317
Permanent Link: http://hdl.handle.net/11104/0326964File Download Size Commentary Version Access 2021_Zalesak_JOURNAL OF ORGANIC CHEMISTRY_11291.pdf 1 2.7 MB Other open-access - 3.0548921 - ÚOCHB 2022 RIV US eng J - Journal Article
Čermáková, Kateřina - Demeulemeester, J. - Lux, Vanda - Nedomová, Monika - Goldman, S. R. - Smith, E. A. - Srb, Pavel - Hexnerová, Rozálie - Fábry, Milan - Mádlíková, Marcela - Hořejší, Magdalena - Rijck, J. D. - Debyser, Z. - Adelman, K. - Hodges, H. C. - Veverka, Václav
A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science. Roč. 374, č. 6571 (2021), s. 1113-1121. ISSN 0036-8075. E-ISSN 1095-9203
R&D Projects: GA ČR(CZ) GA19-14360S; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : mediator subunit med26 * N-terminal domain * structural characterization
OECD category: Biochemistry and molecular biology
Impact factor: 63.832, year: 2021
Method of publishing: Limited access
https://doi.org/10.1126/science.abe2913
Permanent Link: http://hdl.handle.net/11104/0324967 - 4.0541209 - ÚOCHB 2022 RIV GB eng J - Journal Article
Vuorio, J. - Škerlová, Jana - Fábry, M. - Veverka, Václav - Vattulainen, I. - Řezáčová, Pavlína - Martinez-Seara, Hector
N-Glycosylation can selectively block or foster different receptor–ligand binding modes.
Scientific Reports. Roč. 11, č. 1 (2021), č. článku 5239. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA19-19561S; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : glycosylation * ligand binding * sugar-protein interaction
OECD category: Biochemistry and molecular biology
Impact factor: 4.997, year: 2021
Method of publishing: Open access
https://doi.org/10.1038/s41598-021-84569-z
Permanent Link: http://hdl.handle.net/11104/0318805 - 5.0540888 - ÚOCHB 2022 RIV US eng J - Journal Article
Jílková, Adéla - Rubešová, Petra - Fanfrlík, Jindřich - Fajtová, Pavla - Řezáčová, Pavlína - Brynda, Jiří - Lepšík, Martin - Mertlíková-Kaiserová, Helena - Emal, C. D. - Renslo, A. R. - Roush, W. R. - Horn, Martin - Caffrey, C. R. - Mareš, Michael
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors.
ACS Infectious Diseases. Roč. 7, č. 5 (2021), s. 1077-1088. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) LTAUSA19109; GA MŠMT(CZ) LH15040; GA MŠMT LO1302; GA MZd(CZ) NV18-05-00345; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : cathepsin B * cysteine peptidase * drug target * parasite * Schistosoma mansoni * vinyl sulfone inhibitor
OECD category: Biochemistry and molecular biology
Impact factor: 5.578, year: 2021
Method of publishing: Open access
https://doi.org/10.1021/acsinfecdis.0c00501
Permanent Link: http://hdl.handle.net/11104/0318491 - 6.0539544 - ÚOCHB 2022 RIV CH eng J - Journal Article
Van Belle, S. - El Ashkar, S. - Čermáková, Kateřina - Matthijssens, F. - Goossens, S. - Canella, A. - Hodges, C. H. - Christ, F. - De Rijck, J. - Van Vlierberghe, P. - Veverka, Václav - Debyser, Z.
Unlike its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.
Cells. Roč. 10, č. 1 (2021), č. článku 192. E-ISSN 2073-4409
R&D Projects: GA ČR(CZ) GA16-06357S; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : leukemia * molecular cell biology * protein complex * protein-protein interaction * nuclear magnetic resonance (NMR) * animal model * cell culture * hematopoietic stem cell * cell proliferation
OECD category: Biochemistry and molecular biology
Impact factor: 7.666, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/cells10010192
Permanent Link: http://hdl.handle.net/11104/0317595 - 7.0537196 - ÚOCHB 2021 RIV DE eng J - Journal Article
Pomeislová, Alice - Vrzal, Lukáš - Kozák, Jaroslav - Dobiaš, Juraj - Hubálek, Martin - Dvořáková, H. - Reyes Gutierrez, Paul Eduardo - Teplý, Filip - Veverka, Václav
Kinetic Target-Guided Synthesis of Small-Molecule G-Quadruplex Stabilizers.
ChemistryOpen. Roč. 9, č. 12 (2020), s. 1236-1250. ISSN 2191-1363. E-ISSN 2191-1363
R&D Projects: GA ČR(CZ) GA17-04393S; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LK11205; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : anticancer therapy * click chemistry * G-quadruplex * NMR * secondary structures
OECD category: Organic chemistry
Impact factor: 2.911, year: 2020
Method of publishing: Open access
https://doi.org/10.1002/open.202000261
Permanent Link: http://hdl.handle.net/11104/0316292 - 8.0533337 - ÚOCHB 2021 RIV GB eng J - Journal Article
Lux, Vanda - Brouns, T. - Čermáková, Kateřina - Srb, Pavel - Fábry, M. - Mádlíková, Marcela - Hořejší, M. - Kukačka, Zdeněk - Novák, Petr - Kugler, Michael - Brynda, Jiří - DeRijck, J. - Christ, F. - Debyser, Z. - Veverka, Václav
Molecular Mechanism of LEDGF/p75 Dimerization.
Structure. Roč. 28, č. 12 (2020), s. 1288-1299. ISSN 0969-2126. E-ISSN 1878-4186
R&D Projects: GA ČR(CZ) GA16-06357S; GA ČR(CZ) GA16-24309S; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) ED1.1.00/02.0109
EU Projects: European Commission(XE) 731077 - EU_FT-ICR_MS
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : protein-protein interaction * mixed-lineage leukemia * epigenetics transcription * PSIP1 * domain swapping * eletrostatic stapling * paramagnetic NMR
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (MBU-M)
Impact factor: 5.006, year: 2020
Method of publishing: Limited access
https://doi.org/10.1016/j.str.2020.08.012
Permanent Link: http://hdl.handle.net/11104/0311763 - 9.0531602 - ÚEB 2021 RIV US eng J - Journal Article
Kováč, O. - Zálešák, F. - J.-Y. D. Bon, D. - Roiser, L. - Baar, L. V. - Waser, M. - Pospíšil, Jiří
Trisubstituted Highly Activated Benzo[ d]thiazol-2-yl-sulfone-Containing Olefins as Building Blocks in Organic Synthesis.
Journal of Organic Chemistry. Roč. 85, č. 11 (2020), s. 7192-7206. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LO1204; GA MŠMT(CZ) EF16_019/0000738
Institutional support: RVO:61389030
Keywords : DIVERSITY-ORIENTED SYNTHESIS * PRACTICAL SYNTHESIS * MICHAEL ACCEPTORS
OECD category: Organic chemistry
Impact factor: 4.354, year: 2020
Method of publishing: Open access
http://doi.org/10.1021/acs.joc.0c00571
Permanent Link: http://hdl.handle.net/11104/0310234File Download Size Commentary Version Access 2020_Kovac_JOURNAL OF ORGANIC CHEMISTRY_7192.pdf 1 2.2 MB Other open-access - 10.0531086 - MBÚ 2020 RIV NL eng J - Journal Article
Suková, Anna - Bumba, Ladislav - Srb, Pavel - Veverka, Václav - Staněk, Ondřej - Holubová, Jana - Chmelík, Josef - Fišer, Radovan - Šebo, Peter - Mašín, Jiří
Negative charge of the AC-to-Hly linking segment modulates calcium-dependent membrane activities of Bordetella adenylate cyclase toxin.
Biochimica Et Biophysica Acta-Biomembranes. Roč. 1862, č. 9 (2020), č. článku 183310. ISSN 0005-2736. E-ISSN 1879-2642
R&D Projects: GA ČR(CZ) GA19-04607S; GA ČR(CZ) GA19-15175S; GA ČR(CZ) GA18-20621S; GA MŠMT(CZ) LO1509; GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : Adenylate cyclase toxin * AC-to-Hly linking segment * Membrane penetration
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 3.747, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0005273620301413
Permanent Link: http://hdl.handle.net/11104/0309834