Search results
- 1.0547996 - ÚEB 2022 RIV GB eng J - Journal Article
Kiss, M. A. - Peřina, M. - Bazgier, Václav - May, N. V. - Baji, Á. - Jorda, R. - Frank, É.
Synthesis of dihydrotestosterone derivatives modified in the A-ring with (hetero)arylidene, pyrazolo[1,5-a]pyrimidine and triazolo[1,5-a]pyrimidine moieties and their targeting of the androgen receptor in prostate cancer.
Journal of Steroid Biochemistry and Molecular Biology. Roč. 211, JUL (2021), č. článku 105904. ISSN 0960-0760
R&D Projects: GA ČR GA20-15621S; GA MŠMT(CZ) LM2018131
Institutional support: RVO:61389030
Keywords : 2-arylidene-dihydrotestosterone * Androgen receptor * Azolo[1,5-a]pyrimidines * Crystal structures * Flexible docking * Heterocyclization * Transcriptional activity
OECD category: Biochemistry and molecular biology
Impact factor: 5.011, year: 2021
Method of publishing: Open access
http://doi.org/10.1016/j.jsbmb.2021.105904
Permanent Link: http://hdl.handle.net/11104/0324132File Download Size Commentary Version Access 2021_Kiss_JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY_105904.pdf 1 4.1 MB Other open-access - 2.0543685 - ÚEB 2022 RIV CH eng J - Journal Article
Diachkov, Mikhail V. - Ferrer, Karoll - Oklešťková, Jana - Rárová, Lucie - Bazgier, Václav - Kvasnica, Miroslav
Synthesis and biological activity of brassinosteroid analogues with a nitrogen-containing side chain.
International Journal of Molecular Sciences. Roč. 22, č. 1 (2021), č. článku 155. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA19-01383S; GA MŠMT(CZ) EF16_019/0000827
Institutional support: RVO:61389030
Keywords : Brassinosteroid * Cytotoxicity * Nitrogen-containing steroid * Organic synthesis * Plant bioassay
OECD category: Organic chemistry
Impact factor: 6.208, year: 2021
Method of publishing: Open access
http://doi.org/10.3390/ijms22010155
Permanent Link: http://hdl.handle.net/11104/0320865File Download Size Commentary Version Access 2021_Diachkov_INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES_155.pdf 2 1.3 MB Other open-access - 3.0509260 - ÚEB 2020 RIV FR eng J - Journal Article
Jorda, Radek - Řezníčková, Eva - Kiełczewska, U. - Maj, J. - Morzycki, J.W. - Siergiejczyk, L. - Bazgier, Václav - Berka, K. - Rárová, Lucie - Wojtkielewicz, A.
Synthesis of novel galeterone derivatives and evaluation of their in vitro activity against prostate cancer cell lines.
European Journal of Medicinal Chemistry. Roč. 179, OCT 1 (2019), s. 483-492. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA19-01383S; GA MŠMT(CZ) LM2015047
Institutional support: RVO:61389030
Keywords : Galeterone * Prostate * Steroid
OECD category: Organic chemistry
Impact factor: 5.573, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.1016/j.ejmech.2019.06.040
Permanent Link: http://hdl.handle.net/11104/0300005File Download Size Commentary Version Access 2019_Jorda_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_483.pdf 1 2.2 MB Other open-access - 4.0467239 - ÚEB 2017 RIV US eng J - Journal Article
Bazgier, Václav - Berka, K. - Otyepka, M. - Banáš, P.
Exponential Repulsion Improves Structural Predictability of Molecular Docking.
Journal of Computational Chemistry. Roč. 37, č. 28 (2016), s. 2485-2494. ISSN 0192-8651. E-ISSN 1096-987X
Institutional support: RVO:61389030
Keywords : cyclin-dependent kinases * structure-based design * scoring functions * cdk2 inhibitors * force-field * ligand interactions * drug discovery * purine * potent * protein-kinase-2 * molecular docking * dock 6.6 * drug design * cyclin-dependent kinase 2 * directory of decoys
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 3.229, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265352File Download Size Commentary Version Access 2016_Bazgier_JOURNAL OF COMPUTATIONAL CHEMISTRY_2485.pdf 0 445.8 KB Other open-access - 5.0465178 - ÚEB 2017 RIV FR eng J - Journal Article
Lamie, P.F. - Ali, W.A.M. - Bazgier, Václav - Rárová, Lucie
Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.
European Journal of Medicinal Chemistry. Roč. 123, NOV 10 (2016), s. 803-813. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : Indole derivatives * Antiproliferative activity * Anti-inflammatory activity
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.519, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263843File Download Size Commentary Version Access 2016_Lamie_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_803.pdf 1 1.3 MB Other open-access - 6.0464462 - ÚEB 2017 RIV GB eng J - Journal Article
Kvasnica, Miroslav - Oklešťková, Jana - Bazgier, Václav - Rárová, L. - Kořínková, Petra - Mikulík, Jaromír - Buděšínský, Miloš - Béreš, T. - Berka, K. - Lu, Q. - Russinova, E. - Strnad, Miroslav
Design, synthesis and biological activities of new brassinosteroid analogues with a phenyl group in the side chain.
Organic & Biomolecular Chemistry. Roč. 14, č. 37 (2016), s. 8691-8701. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR GJ15-08202Y; GA MŠMT(CZ) LM2015047
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : ASYMMETRIC DIHYDROXYLATION * IMMUNOMODULATORY ACTIVITY * BRI1
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.564, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263315File Download Size Commentary Version Access 2016_Kvasnica_ORGANIC & BIOMOLECULAR CHEMISTRY_8691.pdf 2 1.4 MB Other open-access - 7.0463803 - ÚEB 2017 RIV NL eng J - Journal Article
Nisler, Jaroslav - Kopečný, D. - Končitíková, R. - Zatloukal, Marek - Bazgier, Václav - Berka, K. - Zalabák, D. - Briozzo, P. - Strnad, Miroslav - Spíchal, Lukáš
Novel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase.
Plant Molecular Biology. Roč. 92, 1-2 (2016), s. 235-248. ISSN 0167-4412. E-ISSN 1573-5028
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR GA15-22322S
Institutional support: RVO:61389030
Keywords : Cytokinin oxidase/dehydrogenase * Crystal structure * Molecular docking
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.356, year: 2016
Permanent Link: http://hdl.handle.net/11104/0262934File Download Size Commentary Version Access 2016_Nisler_PLANT MOLECULAR BIOLOGY_235.pdf 0 2.1 MB Other open-access - 8.0459008 - ÚEB 2017 RIV FR eng J - Journal Article
Baltus, C.B. - Jorda, Radek - Marot, Ch. - Berka, K. - Bazgier, Václav - Kryštof, Vladimír - Prie, G. - Viaud-Massuard, M.C.
Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors.
European Journal of Medicinal Chemistry. Roč. 108, JAN 27 (2016), s. 701-719. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : Cyclin-dependent kinase 2 * Kinase inhibitors * Anti-tumor agent
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.519, year: 2016
Permanent Link: http://hdl.handle.net/11104/0259205File Download Size Commentary Version Access 2016_Baltus_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_701.pdf 2 1.9 MB Other open-access - 9.0454968 - ÚEB 2016 RIV GB eng J - Journal Article
Řezníčková, Eva - Weitensteiner, S. - Havlíček, Libor - Jorda, Radek - Gucký, Tomáš - Berka, K. - Bazgier, Václav - Zahler, S. - Kryštof, Vladimír - Strnad, Miroslav
Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.
Chemical Biology & Drug Design. Roč. 86, č. 6 (2015), s. 1528-1540. ISSN 1747-0277. E-ISSN 1747-0285
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA14-19590S; GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : angiogenesis * apoptosis * aurora A
Subject RIV: CE - Biochemistry
Impact factor: 2.802, year: 2015
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord&UT=000367376800022
Permanent Link: http://hdl.handle.net/11104/0255626File Download Size Commentary Version Access 2015_Reznickova_CHEMICAL BIOLOGY & DRUG DESIGN_1528.pdf 1 2.2 MB Other open-access - 10.0446880 - ÚEB 2016 RIV GB eng J - Journal Article
Řezníčková, Eva - Popa, Alexandr - Gucký, Tomáš - Zatloukal, Marek - Havlíček, Libor - Bazgier, Václav - Berka, K. - Jorda, Radek - Popa, Igor - Nasereddin, A. - Jaffe, Ch. L. - Kryštof, Vladimír - Strnad, Miroslav
2,6,9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro.
Bioorganic and Medicinal Chemistry Letters. Roč. 25, č. 11 (2015), s. 2298-2301. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : Purine * Cyclin-dependent kinase * Leishmania
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.486, year: 2015
Permanent Link: http://hdl.handle.net/11104/0248830File Download Size Commentary Version Access 2015_Reznickova_BIOORGANIC & MEDICINAL CHEMISTRY LETTERS_2298.pdf 3 588.8 KB Other open-access