Search results

  1. 1.
    0555576 - BFÚ 2022 RIV SE eng J - Journal Article
    Vičar, Tomáš - Gumulec, J. - Kolář, R. - Kopečná, Olga - Pagáčová, Eva - Falková, Iva - Falk, Martin
    DeepFoci: Deep learning-based algorithm for fast automatic analysis of DNA double-strand break ionizing radiation-induced foci.
    Computational and Structural Biotechnology Journal. Roč. 19, DEC 2021 (2021), s. 6465-6480. ISSN 2001-0370. E-ISSN 2001-0370
    R&D Projects: GA ČR GC20-04109J; GA ČR(CZ) GA19-09212S
    Institutional support: RVO:68081707
    Keywords : alternative splicing variant * complex cell responses * gamma-h2ax foci * chromatin-structure * h2ax phosphorylation * nanoscopy techniques * histone h2ax
    OECD category: Biochemistry and molecular biology
    Impact factor: 6.155, year: 2021
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S2001037021004840?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0330038
     
     
  2. 2.
    0553059 - BFÚ 2023 RIV CH eng J - Journal Article
    Dobešová, Eva - Gier, T. - Kopečná, Olga - Pagáčová, Eva - Vicar, T. - Bestvater, F. - Toufar, Jiří - Bačíková, Alena - Kopel, P. - Fedr, Radek - Hildenbrand, G. - Falková, Iva - Falk, Martin - Hausmann, M.
    Incorporation of Low Concentrations of Gold Nanoparticles: Complex Effects on Radiation Response and Fate of Cancer Cells.
    Pharmaceutics. Roč. 14, č. 1 (2022), č. článku 166. E-ISSN 1999-4923
    R&D Projects: GA ČR GC20-04109J; GA ČR(CZ) GA19-09212S
    Institutional support: RVO:68081707
    Keywords : histone h2ax phosphorylation * double-strand breaks * dna-damage * cellular uptake * dose enhancement * nanoscopy techniques * carcinoma cells * drug-delivery * repair
    OECD category: Pharmacology and pharmacy
    Impact factor: 5.4, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1999-4923/14/1/166
    Permanent Link: https://hdl.handle.net/11104/0340400
     
     
  3. 3.
    0542178 - BFÚ 2022 RIV CH eng J - Journal Article
    Hausmann, M. - Falk, Martin - Neitzel, Ch. - Hofmann, A. - Biswas, A. - Gier, T. - Falková, Iva - Heermann, D.W. - Hildenbrand, G.
    Elucidation of the Clustered Nano-Architecture of Radiation-Induced DNA Damage Sites and Surrounding Chromatin in Cancer Cells: A Single Molecule Localization Microscopy Approach.
    International Journal of Molecular Sciences. Roč. 22, č. 7 (2021), č. článku 3636. E-ISSN 1422-0067
    R&D Projects: GA ČR GC20-04109J
    Institutional support: RVO:68081707
    Keywords : topology of DNA double strand breaks * nano-architecture * ionizing radiation-induced foci (IRIF) * chromatin rearrangements after irradiation * single molecule localization microscopy (SMLM)
    OECD category: Biochemistry and molecular biology
    Impact factor: 6.208, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/22/7/3636
    Permanent Link: http://hdl.handle.net/11104/0319654
     
     
  4. 4.
    0537435 - BFÚ 2021 RIV CH eng J - Journal Article
    Hausmann, M. - Neitzel, Ch. - Bobkova, E. - Nagel, D. - Hofmann, A. - Chramko, T. - Smirnova, E. - Kopečná, Olga - Pagáčová, Eva - Boreyko, A. - Krasavin, E. - Falková, Iva - Heermann, D.W. - Pilarczyk, G. - Hildenbrand, G. - Bestvater, F. - Falk, Martin
    Single Molecule Localization Microscopy Analyses of DNA-Repair Foci and Clusters Detected Along Particle Damage Tracks.
    Frontiers in Physics. Roč. 8, č. 2020 (2020), č. článku 578662. ISSN 2296-424X. E-ISSN 2296-424X
    R&D Projects: GA ČR GC20-04109J
    Institutional support: RVO:68081707
    Keywords : strand-break repair * complex cell responses * space radiation * alternative pathways * nanoscopy techniques * genomic instability * light-microscopy * high-let
    OECD category: Physical chemistry
    Impact factor: 3.560, year: 2020
    Method of publishing: Open access
    http://apps.webofknowledge.com/InboundService.do?customersID=Alerting&mode=FullRecord&IsProductCode=Yes&product=WOS&Init=Yes&Func=Frame&DestFail=http%3A%2F%2Fwww.webofknowledge.com&action=retrieve&SrcApp=Alerting&SrcAuth=Alerting&SID=F5ecl7TTnxXPl2FJDDH&UT=WOS%3A000591310500001
    Permanent Link: http://hdl.handle.net/11104/0315158
     
     
  5. 5.
    0532226 - ÚJF 2021 RIV CH eng J - Journal Article
    Jelínek Michaelidesová, Anna - Vachelová, Jana - Konířová, Jana - Urban, T. - Pachnerová Brabcová, Kateřina - Kaczor, S. - Falk, Martin - Falková, Iva - Depeš, Daniel - Vondráček, V. - Davídková, Marie
    In Vitro Comparison of Passive and Active Clinical Proton Beams.
    International Journal of Molecular Sciences. Roč. 21, č. 16 (2020), č. článku 5650. E-ISSN 1422-0067
    R&D Projects: GA ČR GC20-04109J
    EU Projects: European Commission(XE) 730983 - INSPIRE
    Institutional support: RVO:68081707 ; RVO:61389005
    Keywords : proton therapy * pencil beam scanning * double scattering * cell survival
    OECD category: Biophysics; Biochemistry and molecular biology (BFU-R)
    Impact factor: 5.924, year: 2020
    Method of publishing: Open access
    https://doi.org/10.3390/ijms21165650
    Permanent Link: http://hdl.handle.net/11104/0310797
    FileDownloadSizeCommentaryVersionAccess
    0532226.pdf02.4 MBOpen Access - CC licencePublisher’s postprintopen-access
     
     
  6. 6.
    0507904 - FZÚ 2020 RIV US eng J - Journal Article
    Kratochvílová, Irena - Kopečná, Olga - Bačíková, Alena - Pagáčová, Eva - Falková, Iva - Follett, S.E. - Elliott, K.W. - Varga, K. - Golan, Martin - Falk, Martin
    Changes in cryopreserved cell nuclei serve as indicators of processes during freezing and thawing.
    Langmuir. Roč. 35, č. 23 (2019), s. 7496-7508. ISSN 0743-7463
    R&D Projects: GA MŠMT EF16_019/0000760; GA MŠMT EF16_013/0001406; GA MŠMT(CZ) LO1409; GA ČR(CZ) GA15-05095S; GA ČR(CZ) GA16-12454S; GA MZd NV16-29835A
    Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760; OP VVV - SAFMAT(XE) CZ.02.1.01/0.0/0.0/16_013/0001406
    Institutional support: RVO:68378271 ; RVO:68081707
    Keywords : cryopreservation * chromatin condensation * cell nuclei membrane
    OECD category: Biophysics; Physical chemistry (BFU-R)
    Impact factor: 3.557, year: 2019
    Method of publishing: Limited access
    https://doi.org/10.1021/acs.langmuir.8b02742
    Permanent Link: http://hdl.handle.net/11104/0298867
     
     
  7. 7.
    0504530 - BFÚ 2020 RIV CH eng J - Journal Article
    Pagáčová, Eva - Štefančíková, Lenka - Schmidt-Kaler, F. - Hildenbrand, G. - Vicar, T. - Depeš, Daniel - Lee, J.H. - Bestvater, F. - Lacombe, S. - Porcel, E. - Roux, S. - Wenz, F. - Kopečná, Olga - Falková, Iva - Hausmann, M. - Falk, Martin
    Challenges and Contradictions of Metal Nano-Particle Applications for Radio-Sensitivity Enhancement in Cancer Therapy.
    International Journal of Molecular Sciences. Roč. 20, č. 3 (2019), č. článku 588. E-ISSN 1422-0067
    R&D Projects: GA MZd NV16-29835A; GA ČR(CZ) GA16-12454S
    Institutional support: RVO:68081707
    Keywords : complex cell responses * gold nanoparticles * dna-damage * radiation-therapy
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.556, year: 2019
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/20/3/588/pdf
    Permanent Link: http://hdl.handle.net/11104/0296141
     
     
  8. 8.
    0501639 - BFÚ 2019 RIV CH eng J - Journal Article
    Bobkova, E. - Depeš, Daniel - Lee, J.H. - Jezkova, L. - Falková, Iva - Pagáčová, Eva - Kopečná, Olga - Zadneprianetc, M. - Bačíková, Alena - Kulikova, E. - Smirnova, E. - Bulanova, T. - Boreyko, A. - Krasavin, E. - Wenz, F. - Bestvater, F. - Hildenbrand, G. - Hausmann, M. - Falk, Martin
    Recruitment of 53BP1 Proteins for DNA Repair and Persistence of Repair Clusters Differ for Cell Types as Detected by Single Molecule Localization Microscopy.
    International Journal of Molecular Sciences. Roč. 19, č. 12 (2018), č. článku 3713. E-ISSN 1422-0067
    R&D Projects: GA ČR(CZ) GA16-12454S; GA MZd NV16-29835A
    Institutional support: RVO:68081707
    Keywords : strand-break repair * high-let * alternative pathways * h2ax phosphorylation
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.183, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0293634
     
     
  9. 9.
    0495086 - BFÚ 2019 RIV DE eng J - Journal Article
    Depeš, Daniel - Lee, J.H. - Bobkova, E. - Jezkova, L. - Falková, Iva - Bestvater, F. - Pagáčová, Eva - Kopečná, Olga - Zadneprianetc, M. - Bačíková, Alena - Kulikova, E. - Smirnova, E. - Bulanova, T. - Boreyko, A. - Krasavin, E. - Hausmann, M. - Falk, Martin
    Single-molecule localization microscopy as a promising tool for gamma H2AX/53BP1 foci exploration.
    European Physical Journal D. Roč. 72, č. 9 (2018), č. článku 158. ISSN 1434-6060. E-ISSN 1434-6079
    R&D Projects: GA ČR(CZ) GA16-12454S; GA MZd NV16-29835A
    Institutional support: RVO:68081707
    Keywords : double-strand breaks * high-let-irradiation * precision distance microscopy * complex cell responses * linear-energy-transfer * clustered dna-damage * beam cancer-therapy * chromatin-structure * nanoscopy techniques * electron-microscopy
    OECD category: Biochemistry and molecular biology
    Impact factor: 1.331, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0288105
     
     
  10. 10.
    0494984 - BFÚ 2019 RIV GB eng J - Journal Article
    Falk, Martin - Falková, Iva - Kopečná, Olga - Bačíková, Alena - Pagáčová, Eva - Šimek, Daniel - Golan, Martin - Kozubek, Stanislav - Pekarová, Michaela - Follett, S.E. - Klejdus, B. - Elliott, K.W. - Varga, K. - Teplá, O. - Kratochvílová, Irena
    Chromatin architecture changes and DNA replication fork collapse are critical features in cryopreserved cells that are differentially controlled by cryoprotectants.
    Scientific Reports. Roč. 8, OCT 2 2018 (2018), č. článku 14694. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA MZd NV16-29835A; GA ČR(CZ) GA16-12454S; GA MŠMT(CZ) LO1409
    Grant - others:FUNBIO(XE) CZ.2.16/3.1.00/21568
    Institutional support: RVO:68081707 ; RVO:68378271
    Keywords : human spermatozoa * oxidative-stress * damage response * repair * trehalose * integrity * dynamics * sperm * fragmentation * instability
    OECD category: Cell biology; Biophysics (FZU-D)
    Impact factor: 4.011, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0288034
    FileDownloadSizeCommentaryVersionAccess
    0494984.pdf83.9 MBCC licencePublisher’s postprintopen-access
     
     

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