Search results
- 1.0574244 - ÚOCHB 2024 RIV US eng J - Journal Article
Štefek, Milan - Chalupská, Dominika - Chalupský, Karel - Zgarbová, Michala - Dvořáková, Alexandra - Krafčíková, Petra - Li, A. S. M. - Šála, Michal - Dejmek, Milan - Otava, Tomáš - Chaloupecká, Ema - Kozák, Jaroslav - Kozic, Ján - Vedadi, M. - Weber, Jan - Mertlíková-Kaiserová, Helena - Nencka, Radim
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors.
ACS Omega. Roč. 8, č. 30 (2023), s. 27410-27418. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 * genetics * inhibitors
OECD category: Virology
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acsomega.3c02815
Permanent Link: https://hdl.handle.net/11104/0344580File Download Size Commentary Version Access acsomega.3c02815 (2).pdf 0 5.1 MB Publisher’s postprint open-access - 2.0572565 - ÚOCHB 2024 RIV US eng J - Journal Article
Skácel, Jan - Djukic, Stefan - Baszczyňski, Ondřej - Kalčic, Filip - Bílek, Tadeáš - Chalupský, Karel - Kozák, Jaroslav - Dvořáková, Alexandra - Tloušťová, Eva - Kráľová, Zuzana - Šmídková, Markéta - Voldřich, Jan - Rumlová, M. - Pachl, Petr - Brynda, Jiří - Vučková, Tereza - Fábry, Milan - Snášel, Jan - Pichová, Iva - Řezáčová, Pavlína - Mertlíková-Kaiserová, Helena - Janeba, Zlatko
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.
Journal of Medicinal Chemistry. Roč. 66, č. 10 (2023), s. 6652-6681. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA TA ČR(CZ) TN01000013; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT LX22NPO5102
Institutional support: RVO:61388963
Keywords : multisubstrate analog inhibitors * transition-state analog * human erythrocytes
OECD category: Organic chemistry
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.2c02097
Permanent Link: https://hdl.handle.net/11104/0343213File Download Size Commentary Version Access 10.1021acs.jmedchem.2c02097.pdf 1 5.7 MB Publisher’s postprint open-access - 3.0571224 - ÚOCHB 2024 RIV US eng J - Journal Article
Pávová, Marcela - Reyes Gutierrez, Paul Eduardo - Kozák, Jaroslav - Dobiaš, Juraj - Yurenko, Yevgen - Lepšík, Martin - Teplý, Filip - Weber, Jan
Helquat dyes targeting G-quadruplexes as a new class of anti-HIV-1 inhibitors.
Scientific Reports. Roč. 13, April (2023), č. článku 6096. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388963
Keywords : long terminal repeat * promoter * binding
OECD category: Virology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41598-023-33263-3
Permanent Link: https://hdl.handle.net/11104/0342496File Download Size Commentary Version Access s41598-023-33263-3.pdf 1 1.9 MB Publisher’s postprint open-access - 4.0552686 - ÚOCHB 2023 RIV GB eng J - Journal Article
Lášek, Tomáš - Petrová, Magdalena - Markusová Kóšiová, Ivana - Šimák, Ondřej - Buděšínský, Miloš - Kozák, Jaroslav - Snášel, Jan - Vavřina, Zdeněk - Birkuš, Gabriel - Rosenberg, Ivan - Páv, Ondřej
5′-Phosphonate modified oligoadenylates as potent activators of human RNase L.
Bioorganic & Medicinal Chemistry. Roč. 56, Feb 15 (2022), č. článku 116632. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : RNase L * Oligoadenylate * Phosphonate oligonucleotide * OAS-RNase L pathway * 2-5A
OECD category: Biochemistry and molecular biology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2022.116632
Permanent Link: http://hdl.handle.net/11104/0327809 - 5.0543389 - ÚOCHB 2022 RIV GB eng J - Journal Article
Lášek, Tomáš - Dobiaš, Juraj - Buděšínský, Miloš - Kozák, Jaroslav - Lapuníková, Barbora - Rosenberg, Ivan - Birkuš, Gabriel - Páv, Ondřej
Synthesis of phosphonate derivatives of 2′-deoxy-2′-fluorotetradialdose D-nucleosides and tetradialdose D-nucleosides.
Tetrahedron. Roč. 89, Jun 4 (2021), č. článku 132159. ISSN 0040-4020. E-ISSN 1464-5416
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : nucleoside phosphonate * triphosphate * prodrug * tetradialdose d-nucleoside * 2′-fluoronucleoside
OECD category: Organic chemistry
Impact factor: 2.388, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.tet.2021.132159
Permanent Link: http://hdl.handle.net/11104/0320603 - 6.0541460 - ÚOCHB 2022 RIV US eng J - Journal Article
Milisavljevič, Nemanja - Konkoľová, Eva - Kozák, Jaroslav - Hodek, Jan - Veselovská, Lucia - Sýkorová, Veronika - Čížek, Karel - Pohl, Radek - Eyer, Luděk - Svoboda, P. - Růžek, Daniel - Weber, Jan - Nencka, Radim - Bouřa, Evžen - Hocek, Michal
Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses.
ACS Infectious Diseases. Roč. 7, č. 2 (2021), s. 471-478. ISSN 2373-8227
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LTAUSA18016; GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : 7-deazapurine ribonucleosides * monophosphate prodrugs * triphoshates * RNA viruses * 7-deazapurine ribonucleosides monophosphate prodrugs triphoshates RNA viruses antiviral activity
OECD category: Organic chemistry; Biochemistry and molecular biology (BC-A)
Impact factor: 5.578, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.0c00829
Permanent Link: http://hdl.handle.net/11104/0319010 - 7.0538814 - ÚOCHB 2022 RIV US eng J - Journal Article
Dzijak, Rastislav - Galeta, Juraj - Vázquez, Arcadio - Kozák, Jaroslav - Matoušová, Marika - Fulka, Helena - Dračínský, Martin - Vrábel, Milan
Structurally Redesigned Bioorthogonal Reagents for Mitochondria-Specific Prodrug Activation.
JACS Au. Roč. 1, č. 1 (2021), s. 23-30. E-ISSN 2691-3704
R&D Projects: GA ČR(CZ) GA19-13811S
EU Projects: European Commission(XE) 677465 - SWEETOOLS
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : bioorthogonal reactions * click-to-release * mitochondria * prodrug activation * tetrazines
OECD category: Organic chemistry; Medicinal chemistry (UEM-P)
Method of publishing: Open access
https://doi.org/10.1021/jacsau.0c00053
Permanent Link: http://hdl.handle.net/11104/0316967 - 8.0537196 - ÚOCHB 2021 RIV DE eng J - Journal Article
Pomeislová, Alice - Vrzal, Lukáš - Kozák, Jaroslav - Dobiaš, Juraj - Hubálek, Martin - Dvořáková, H. - Reyes Gutierrez, Paul Eduardo - Teplý, Filip - Veverka, Václav
Kinetic Target-Guided Synthesis of Small-Molecule G-Quadruplex Stabilizers.
ChemistryOpen. Roč. 9, č. 12 (2020), s. 1236-1250. ISSN 2191-1363. E-ISSN 2191-1363
R&D Projects: GA ČR(CZ) GA17-04393S; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LK11205; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : anticancer therapy * click chemistry * G-quadruplex * NMR * secondary structures
OECD category: Organic chemistry
Impact factor: 2.911, year: 2020
Method of publishing: Open access
https://doi.org/10.1002/open.202000261
Permanent Link: http://hdl.handle.net/11104/0316292 - 9.0474801 - ÚOCHB 2018 RIV NL eng J - Journal Article
Hercík, Kamil - Kozák, Jaroslav - Šála, Michal - Dejmek, Milan - Hřebabecký, Hubert - Zborníková, Eva - Smola, Miroslav - Růžek, Daniel - Nencka, Radim - Bouřa, Evžen
Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase.
Antiviral Research. Roč. 137, Jan (2017), s. 131-133. ISSN 0166-3542. E-ISSN 1872-9096
R&D Projects: GA ČR GA15-09310S
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : hepatitis C virus * borne encephalitis virus * crystal structure
OECD category: Organic chemistry
Impact factor: 4.307, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271754 - 10.0423951 - ÚEB 2014 RIV US eng J - Journal Article
Holá, Marcela - Kozák, Jaroslav - Vágnerová, Radka - Angelis, Karel
Genotoxin Induced Mutagenesis in the Model Plant Physcomitrella patens.
BioMed Research International. -, ID 535049 (2013). ISSN 2314-6133. E-ISSN 2314-6141
R&D Projects: GA ČR GA13-06595S; GA MŠMT(CZ) LD13006
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : DNA-DAMAGE * COMET ASSAY * ARABIDOPSIS-THALIANA
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0229995