Search results
- 1.0448427 - ÚOCHB 2016 RIV GB eng J - Journal Article
Pachl, Petr - Šimák, Ondřej - Řezáčová, Pavlína - Fábry, Milan - Buděšínský, Miloš - Rosenberg, Ivan - Brynda, Jiří
Structure-based design of a bisphosphonate 5 '(3 ')-deoxyribonucleotidase inhibitor.
MedChemComm. Roč. 6, č. 9 (2015), s. 1635-1638. ISSN 2040-2503. E-ISSN 2040-2511
R&D Projects: GA ČR GA203/09/0820; GA ČR GA13-26526S; GA ČR GA13-24880S
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : mitochondrial deoxyribonucleotidase * crystal structures * 5'-nucleotidases
Subject RIV: CE - Biochemistry; EB - Genetics ; Molecular Biology (UMG-J)
Impact factor: 2.319, year: 2015
Permanent Link: http://hdl.handle.net/11104/0250142 - 2.0448379 - ÚOCHB 2016 RIV GB eng J - Journal Article
Hřebabecký, Hubert - Procházková, Eliška - Šála, Michal - Plačková, Pavla - Tloušťová, Eva - Barauskas, O. - Lee, Y. J. - Tian, Y. - Mackman, R. - Nencka, Radim
Synthesis and biological evaluation of conformationally restricted adenine bicycloribonucleosides.
Organic & Biomolecular Chemistry. Roč. 13, č. 35 (2015), s. 9300-9313. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR GPP207/12/P625; GA ČR GA15-09310S; GA ČR GA13-24880S; GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : nucleic acid analogs * nucleoside triphosphates * sugar ring
Subject RIV: CC - Organic Chemistry
Impact factor: 3.559, year: 2015
http://pubs.rsc.org/en/content/articlepdf/2015/ob/c5ob00987a
Permanent Link: http://hdl.handle.net/11104/0250113 - 3.0446565 - ÚOCHB 2016 RIV US eng J - Journal Article
Petrová, Magdalena - Páv, Ondřej - Buděšínský, Miloš - Zborníková, Eva - Novák, Pavel - Rosenbergová, Šárka - Pačes, Ondřej - Liboska, Radek - Dvořáková, Ivana - Šimák, Ondřej - Rosenberg, Ivan
Straightforward Synthesis of Purine 4 '-Alkoxy-2 '-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4 '-Alkoxyoligodeoxynucleotides as New RNA Mimics.
Organic Letters. Roč. 17, č. 14 (2015), s. 3426-3429. ISSN 1523-7060. E-ISSN 1523-7052
R&D Projects: GA ČR GA13-26526S; GA ČR GA13-24880S; GA TA ČR TA03010598
Institutional support: RVO:61388963
Keywords : 4'-alkoxyoligodeoxynucleotides * RNA mimics * antisense
Subject RIV: CC - Organic Chemistry
Impact factor: 6.732, year: 2015
Permanent Link: http://hdl.handle.net/11104/0248620 - 4.0444048 - ÚOCHB 2016 RIV GB eng J - Journal Article
Pohl, Radek - Poštová Slavětínská, Lenka - Eng, W. S. - Keough, D. T. - Guddat, L. W. - Rejman, Dominik
Synthesis, conformational studies, and biological properties of phosphonomethoxyethyl derivatives of nucleobases with a locked conformation via a pyrrolidine ring.
Organic & Biomolecular Chemistry. Roč. 13, č. 16 (2015), s. 4693-4705. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR GA13-24880S; GA ČR GAP207/11/0108
Institutional support: RVO:61388963
Keywords : nucleoside phosphonates * nucleotide analogs * inhibitors
Subject RIV: CC - Organic Chemistry
Impact factor: 3.559, year: 2015
http://pubs.rsc.org/en/content/articlepdf/2015/ob/c5ob00097a
Permanent Link: http://hdl.handle.net/11104/0246702 - 5.0443577 - ÚOCHB 2016 RIV US eng J - Journal Article
Dračínský, Martin - Pohl, Radek
Determination of the Nucleic Acid Adducts Structure at the Nucleoside/Nucleotide Level by NMR Spectroscopy.
Chemical Research in Toxicology. Roč. 28, č. 2 (2015), s. 155-165. ISSN 0893-228X. E-ISSN 1520-5010
R&D Projects: GA ČR GA13-24880S
Institutional support: RVO:61388963
Keywords : NMR spectroscopy * nucleic acids * nucleotides
Subject RIV: CC - Organic Chemistry
Impact factor: 3.025, year: 2015
Permanent Link: http://hdl.handle.net/11104/0246335 - 6.0443272 - ÚOCHB 2016 RIV GB eng J - Journal Article
Dračínský, Martin - Hodgkinson, P.
Solid-state NMR studies of nucleic acid components.
RSC Advances. Roč. 5, č. 16 (2015), s. 12300-12310. E-ISSN 2046-2069
R&D Projects: GA ČR GA13-24880S
Institutional support: RVO:61388963
Keywords : NMR spectroscopy * nucleic acids * solid-state NMR
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 3.289, year: 2015
http://pubs.rsc.org/en/content/articlepdf/2015/ra/c4ra14404j
Permanent Link: http://hdl.handle.net/11104/0246058 - 7.0435239 - ÚOCHB 2015 RIV GB eng J - Journal Article
Šimák, Ondřej - Pachl, Petr - Fábry, Milan - Buděšínský, Miloš - Jandušík, T. - Hnízda, Aleš - Skleničková, Radka - Petrová, Magdalena - Veverka, Václav - Řezáčová, Pavlína - Brynda, Jiří - Rosenberg, Ivan
Conformationally constrained nucleoside phosphonic acids - potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases.
Organic & Biomolecular Chemistry. Roč. 12, č. 40 (2014), s. 7971-7982. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR GA203/09/0820; GA ČR GA13-24880S; GA ČR GA13-26526S; GA MŠMT(CZ) LK11205; GA AV ČR KAN200520801
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : 5'(3')-nucleotidase * structure * inhibition * cdN * mdN * nucleoside * SAR * phosphonic acid
Subject RIV: CC - Organic Chemistry
Impact factor: 3.562, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239546 - 8.0435160 - ÚOCHB 2015 RIV GB eng J - Journal Article
Čechová, Lucie - Procházková, Eliška - Císařová, I. - Dračínský, Martin - Janeba, Zlatko
Separation of planar rotamers through intramolecular hydrogen bonding in polysubstituted 5-nitrosopyrimidines.
Chemical Communications. Roč. 50, č. 94 (2014), s. 14892-14895. ISSN 1359-7345. E-ISSN 1364-548X
R&D Projects: GA MV VG20102015046; GA ČR GA13-24880S
Institutional support: RVO:61388963
Keywords : hydrogen bonds * 5-nitrosopyrimidines * NMR spectroscopy
Subject RIV: CC - Organic Chemistry
Impact factor: 6.834, year: 2014
http://pubs.rsc.org/en/content/articlepdf/2014/cc/c4cc06978a
Permanent Link: http://hdl.handle.net/11104/0239051 - 9.0431792 - ÚOCHB 2015 RIV DE eng J - Journal Article
Poštová Slavětínská, Lenka - Rejman, Dominik - Pohl, Radek
Pyrrolidine nucleotide analogs with a tunable conformation.
Beilstein Journal of Organic Chemistry. Roč. 10, Aug 22 (2014), s. 1967-1980. ISSN 1860-5397. E-ISSN 1860-5397
R&D Projects: GA ČR GA13-24880S
Institutional support: RVO:61388963
Keywords : conformation * NMR * nucleic acids * nucleotide analog * phosphonic acid * pseudorotation * pyrrolidine
Subject RIV: CC - Organic Chemistry
Impact factor: 2.757, year: 2014
http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-10-205
Permanent Link: http://hdl.handle.net/11104/0236420 - 10.0430610 - ÚOCHB 2015 RIV GB eng J - Journal Article
Dračínský, Martin - Šála, Michal - Hodgkinson, P.
Dynamics of water molecules and sodium ions in solid hydrates of nucleotides.
CrystEngComm. Roč. 16, č. 29 (2014), s. 6756-6764. ISSN 1466-8033
R&D Projects: GA ČR GA13-24880S
Grant - others:Seventh Framework Programme of the European Union(XE) FP7-299242 People
Program: FP7
Institutional support: RVO:61388963
Keywords : molecular dynamics simulations * NMR spectroscopy * DFT calculations
Subject RIV: CC - Organic Chemistry
Impact factor: 4.034, year: 2014
Permanent Link: http://hdl.handle.net/11104/0235573