Search results
- 1.0585631 - ÚOCHB 2025 RIV US eng J - Journal Article
Kim, Y. J. - Pemberton, J. G. - Eisenreichová, Andrea - Mandal, A. - Koukalova, A. - Rohilla, P. - Sohn, M. - Konradi, A. W. - Tang, T. T. - Bouřa, Evžen - Balla, T.
Non-vesicular phosphatidylinositol transfer plays critical roles in defining organelle lipid composition.
EMBO Journal. (2024). ISSN 0261-4189. E-ISSN 1460-2075
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : phosphatidylinositol * non-vesicular lipid * transport * membrane contact sites * phospholipase C
Impact factor: 11.4, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s44318-024-00096-3
Permanent Link: https://hdl.handle.net/11104/0353312File Download Size Commentary Version Access 10.1038s44318-024-00096-3.pdf 0 10.3 MB Publisher’s postprint open-access - 2.0583190 - ÚOCHB 2025 RIV US eng J - Journal Article
Klíma, Martin - Dejmek, Milan - Duchoslav, Vojtěch - Eisenreichová, Andrea - Šála, Michal - Chalupský, Karel - Chalupská, Dominika - Novotná, Barbora - Birkuš, Gabriel - Nencka, Radim - Bouřa, Evžen
Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.
Structure. Roč. 32, č. 4 (2024), s. 433-439. ISSN 0969-2126. E-ISSN 1878-4186
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.str.2024.01.008
Permanent Link: https://hdl.handle.net/11104/0351191File Download Size Commentary Version Access 10.1016j.str.2024.01.008.pdf 0 3.1 MB Publisher’s postprint open-access - 3.0580809 - ÚOCHB 2024 RIV CZ cze J - Journal Article
Bouřa, Evžen
Strukturní biologie v antivirovém výzkumu na příbězích kinas lipidů, proteinu STING a virových methyltransferas.
[Structural Biology in Antiviral Research – A Story Illustrated by the Tales of Lipid Kinases, STING and Viral Methyltransferases.]
Chemické listy. Roč. 117, č. 12 (2023), s. 755-763. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : antivirals * lipid kinase * STING * methyltransferase * virus
OECD category: Virology
Impact factor: 0.6, year: 2022
Method of publishing: Open access
https://doi.org/10.54779/chl20230755
Permanent Link: https://hdl.handle.net/11104/0349574File Download Size Commentary Version Access 10.54779chl20230755.pdf 0 1.5 MB Publisher’s postprint open-access - 4.0579447 - ÚOCHB 2025 RIV GB eng J - Journal Article
Misehe, Mbilo - Šála, Michal - Matoušová, Marika - Hercík, Kamil - Kocek, Hugo - Chalupská, Dominika - Chaloupecká, Ema - Hájek, Miroslav - Bouřa, Evžen - Mertlíková-Kaiserová, Helena - Nencka, Radim
Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors.
Bioorganic & Medicinal Chemistry. Roč. 97, January (2024), č. článku 129567. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : kinase inhibitor * thieno [2,3d] pyrimidine derivative * receptor-interacting protein kinase 2 * RIPK2 * NOD
Impact factor: 3.5, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.bmcl.2023.129567
Permanent Link: https://hdl.handle.net/11104/0348249File Download Size Commentary Version Access 10.1016j.bmcl.2023.129567.pdf 0 1.6 MB Publisher’s postprint open-access - 5.0576080 - ÚOCHB 2024 RIV NL eng J - Journal Article
Zgarbová, Michala - Otava, Tomáš - Šilhán, Jan - Nencka, Radim - Weber, Jan - Bouřa, Evžen
Inhibitors of mpox VP39 2′-O methyltransferase efficiently inhibit the monkeypox virus.
Antiviral Research. Roč. 218, October (2023), č. článku 105714. ISSN 0166-3542. E-ISSN 1872-9096
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : structural basis
OECD category: Virology
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.antiviral.2023.105714
Permanent Link: https://hdl.handle.net/11104/0345703File Download Size Commentary Version Access 10.1016j.antiviral.2023.105714.pdf 0 1.7 MB Publisher’s postprint open-access - 6.0575761 - ÚOCHB 2024 RIV NL eng J - Journal Article
Eisenreichová, Andrea - Humpolíčková, Jana - Różycki, B. - Bouřa, Evžen - Koukalová, Alena
Effects of biophysical membrane properties on recognition of phosphatidylserine, or phosphatidylinositol 4-phosphate by lipid biosensors LactC2, or P4M.
Biochimie. Roč. 215, December (2023), s. 42-49. ISSN 0300-9084. E-ISSN 1638-6183
R&D Projects: GA ČR(CZ) GF21-27735K
Institutional support: RVO:61388963
Keywords : lipid biosensors * LactC2 * P4M * membrane properties * negatively charged lipids * membrane fluidity * phosphatidylinositol 4-phosphate * phosphatidylserine * LUVs
OECD category: Biochemistry and molecular biology
Impact factor: 3.9, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.biochi.2023.09.003
Permanent Link: https://hdl.handle.net/11104/0345489 - 7.0574898 - ÚOCHB 2024 RIV NL eng J - Journal Article
Misehe, Mbilo - Matoušová, Marika - Dvořáková, Alexandra - Hercík, Kamil - Škach, Kryštof - Chalupská, Dominika - Dejmek, Milan - Šála, Michal - Hájek, Miroslav - Bouřa, Evžen - Mertlíková-Kaiserová, Helena - Nencka, Radim
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases.
European Journal of Medicinal Chemistry. Roč. 260, November (2023), č. článku 115717. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LX22NPO5103; GA MZd(CZ) NU20-05-00472
Institutional support: RVO:61388963
Keywords : kinase inhibitor * quinazoline derivatives * RIPK2 * NOD * inflammation * RIPK3
OECD category: Medicinal chemistry
Impact factor: 6.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2023.115717
Permanent Link: https://hdl.handle.net/11104/0344824File Download Size Commentary Version Access 10.1016j.ejmech.2023.115717.pdf 0 4.4 MB Publisher’s postprint open-access - 8.0574877 - ÚOCHB 2024 RIV CH eng J - Journal Article
Eisenreichová, Andrea - Klíma, Martin - Anila, M. M. - Koukalová, Alena - Humpolíčková, Jana - Rozycki, B. - Bouřa, Evžen
Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport.
Cells. Roč. 12, č. 15 (2023), č. článku 1974. E-ISSN 2073-4409
R&D Projects: GA ČR(CZ) GF21-27735K
Institutional support: RVO:61388963
Keywords : lipid transport * ORD * ORP8 * PS * PI4P * plasma membrane * ER
OECD category: Biochemistry and molecular biology
Impact factor: 6, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/cells12151974
Permanent Link: https://hdl.handle.net/11104/0344801
Research data: PDB - 9.0574383 - ÚOCHB 2024 RIV NL eng J - Journal Article
Dejmek, Milan - Brázdová, Andrea - Otava, Tomáš - Pimková Polidarová, Markéta - Klíma, Martin - Smola, Miroslav - Vavřina, Zdeněk - Buděšínský, Miloš - Dračínský, Martin - Liboska, Radek - Bouřa, Evžen - Birkuš, Gabriel - Nencka, Radim
Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy.
European Journal of Medicinal Chemistry. Roč. 259, November (2023), č. článku 115685. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LX22NPO5103; GA MZd(CZ) NU20-05-00472
Research Infrastructure: CCP II - 90126
Institutional support: RVO:61388963
Keywords : cyclic dinucleotides * STING * cancer * intratumoral administration * immunotherapy
OECD category: Medicinal chemistry
Impact factor: 6.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2023.115685
Permanent Link: https://hdl.handle.net/11104/0344716File Download Size Commentary Version Access 10.1016j.ejmech.2023.115685.pdf 0 5.2 MB Publisher’s postprint open-access
Research data: PDB - 10.0574116 - ÚEM 2024 RIV US eng J - Journal Article
Kortus, Štěpán - Řeháková, Kristýna - Klíma, Martin - Kolcheva, Marharyta - Ladislav, Marek - Langore, Emily - Baráčková, Petra - Netolický, Jakub - Misiachna, Anna - Hemelíková, Katarína - Humpolíčková, Jana - Chalupská, Dominika - Šilhán, Jan - Kaniaková, Martina - Hrčka Krausová, Barbora - Bouřa, Evžen - Zápotocký, Martin - Horák, Martin
Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes.
Journal of Neuroscience. Roč. 43, č. 26 (2023), s. 4755-4774. ISSN 0270-6474. E-ISSN 1529-2401
R&D Projects: GA ČR(CZ) GA20-12420S; GA MŠMT(CZ) LX22NPO5107
Research Infrastructure: Czech-BioImaging III - 90250; Czech-BioImaging II - 90129
Institutional support: RVO:68378041 ; RVO:61388963 ; RVO:67985823
Keywords : GluN subunit * excitatory synapse * glutamate receptor * lateral diffusion * live microscopy * mammalian neuron
OECD category: Neurosciences (including psychophysiology; Biochemistry and molecular biology (UOCHB-X); Biochemistry and molecular biology (FGU-C)
Impact factor: 5.3, year: 2022
Method of publishing: Open access
https://www.jneurosci.org/content/43/26/4755
Permanent Link: https://hdl.handle.net/11104/0344475File Download Size Commentary Version Access Kortus 2023.pdf 4 4.6 MB Publisher’s postprint open-access