Search results

  1. 1.
    0519252 - ÚOCHB 2020 RIV CH eng J - Journal Article
    Beranová, Jana - Knedlík, Tomáš - Šimková, Adéla - Šubr, Vladimír - Kostka, Libor - Etrych, Tomáš - Šácha, Pavel - Konvalinka, Jan
    Tris-(Nitrilotriacetic Acid)-Decorated Polymer Conjugates as Tools for Immobilization and Visualization of His-Tagged Proteins.
    Catalysts. Roč. 9, č. 12 (2019), č. článku 1011. E-ISSN 2073-4344
    R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MPO(CZ) FV10490; GA MPO(CZ) FV10370; GA ČR(CZ) GA19-10280S; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:61388963 ; RVO:61389013
    Keywords : antibody mimetics * protein immobilization * His-tag * tris-nitrilotriacetic acid (tris-NTA) * iBodies * biocompatible polymers * N-(2-hydroxypropyl) methacrylamide (HPMA)
    OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
    Impact factor: 3.520, year: 2019
    Method of publishing: Open access
    https://www.mdpi.com/2073-4344/9/12/1011
    Permanent Link: http://hdl.handle.net/11104/0304263
    FileDownloadSizeCommentaryVersionAccess
    0519252.pdf101.6 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0510216 - ÚOCHB 2020 RIV US eng J - Journal Article
    Vorlová, Barbora - Knedlík, Tomáš - Tykvart, Jan - Konvalinka, Jan
    GCPII and its close homolog GCPIII: from a neuropeptidase to a cancer marker and beyond.
    Frontiers in Bioscience. Roč. 24, č. 4 (2019), s. 648-687. ISSN 1093-9946. E-ISSN 1093-4715
    R&D Projects: GA MŠMT LO1302
    Institutional support: RVO:61388963
    Keywords : GCPII * GCPIII * PSMA * FOLH1 * NAALAD2 * NAAG * folate * BCG * Review
    OECD category: Biochemistry and molecular biology
    Impact factor: 2.747, year: 2019
    Method of publishing: Limited access
    http://www.bioscience.org/2019/v24/af/4742/list.htm
    Permanent Link: http://hdl.handle.net/11104/0300749
     
     
  3. 3.
    0505496 - ÚOCHB 2020 RIV US eng J - Journal Article
    Pospíšilová, Klára - Knedlík, Tomáš - Šácha, Pavel - Kostka, Libor - Schimer, Jiří - Brynda, Jiří - Král, V. - Cígler, Petr - Navrátil, Václav - Etrych, Tomáš - Šubr, Vladimír - Kugler, Michael - Fábry, M. - Řezáčová, Pavlína - Konvalinka, Jan
    Inhibitor-Polymer Conjugates as a Versatile Tool for Detection and Visualization of Cancer-Associated Carbonic Anhydrase Isoforms.
    ACS Omega. Roč. 4, č. 4 (2019), s. 6746-6756. ISSN 2470-1343. E-ISSN 2470-1343
    R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT(CZ) LO1304; GA MŠMT LO1302; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT EF16_026/0008382
    Institutional support: RVO:61388963 ; RVO:61389013
    Keywords : renal-cell carcinoma * molecule-drug conjugate * intrinsic marker
    OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
    Impact factor: 2.870, year: 2019
    Method of publishing: Open access
    https://pubs.acs.org/doi/10.1021/acsomega.9b00596
    Permanent Link: http://hdl.handle.net/11104/0296982
     
     
  4. 4.
    0499970 - ÚOCHB 2019 RIV US eng J - Journal Article
    Šimon, Petr - Knedlík, Tomáš - Blažková, Kristýna - Dvořáková, Petra - Březinová, Anna - Kostka, Libor - Šubr, Vladimír - Konvalinka, Jan - Šácha, Pavel
    Identification of Protein Targets of Bioactive Small Molecules Using Randomly Photomodified Probes.
    ACS Chemical Biology. Roč. 13, č. 12 (2018), s. 3333-3342. ISSN 1554-8929. E-ISSN 1554-8937
    R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT LO1302; GA MZd(CZ) NV15-31379A
    Institutional support: RVO:61388963 ; RVO:61389013
    Keywords : glutamate carboxypeptidase II * inhibitor * design
    OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
    Impact factor: 4.374, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0292149
     
     
  5. 5.
    0481818 - ÚOCHB 2018 RIV US eng J - Journal Article
    Dvořáková, Petra - Bušek, P. - Knedlík, Tomáš - Schimer, Jiří - Etrych, Tomáš - Kostka, Libor - Stollinová Šromová, L. - Šubr, Vladimír - Šácha, Pavel - Šedo, A. - Konvalinka, Jan
    Inhibitor-decorated Polymer Conjugates Targeting Fibroblast Activation Protein.
    Journal of Medicinal Chemistry. Roč. 60, č. 20 (2017), s. 8385-8393. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) LM2015064; GA MŠMT LO1302
    Institutional support: RVO:61388963 ; RVO:61389013
    Keywords : dipeptidyl peptidase IV * metastatic colorectal cancer * integral membrane protease
    OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
    Impact factor: 6.253, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0277469
     
     
  6. 6.
    0479478 - ÚOCHB 2018 RIV GB eng J - Journal Article
    Knedlík, Tomáš - Vorlová, Barbora - Navrátil, Václav - Tykvart, Jan - Sedlák, František - Vaculín, Š. - Franěk, M. - Šácha, Pavel - Konvalinka, Jan
    Mouse glutamate carboxypeptidaseII (GCPII) has a similar enzyme activity and inhibition profile but a different tissue distribution to human GCPII.
    FEBS Open Bio. Roč. 7, č. 9 (2017), s. 1362-1378. ISSN 2211-5463. E-ISSN 2211-5463
    R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT LO1302
    Institutional support: RVO:61388963
    Keywords : glutamate carboxypeptidase II * mouse animal model * neuronal disorders * prostate cancer * prostate-specific membrane antigen
    OECD category: Biochemistry and molecular biology
    Impact factor: 1.782, year: 2017
    http://onlinelibrary.wiley.com/doi/10.1002/2211-5463.12276/full
    Permanent Link: http://hdl.handle.net/11104/0275468
     
     
  7. 7.
    0475093 - ÚOCHB 2018 RIV GB eng J - Journal Article
    Navrátil, Václav - Schimer, Jiří - Tykvart, Jan - Knedlík, Tomáš - Vik, V. - Majer, Pavel - Konvalinka, Jan - Šácha, Pavel
    DNA-linked Inhibitor Antibody Assay (DIANA) for sensitive and selective enzyme detection and inhibitor screening.
    Nucleic Acids Research. Roč. 45, č. 2 (2017), č. článku e10. ISSN 0305-1048. E-ISSN 1362-4962
    R&D Projects: GA MŠMT LO1302
    Institutional support: RVO:61388963
    Keywords : quantitative PCR * enzyme detection * inhibitor screening
    OECD category: Biochemical research methods
    Impact factor: 11.561, year: 2017
    https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkw853
    Permanent Link: http://hdl.handle.net/11104/0271968
    FileDownloadSizeCommentaryVersionAccess
    0475093.pdf41.8 MBPublisher’s postprintopen-access
     
     
  8. 8.
    0458826 - ÚOCHB 2017 RIV DE eng J - Journal Article
    Šácha, Pavel - Knedlík, Tomáš - Schimer, Jiří - Tykvart, Jan - Parolek, Jan - Navrátil, Václav - Dvořáková, Petra - Sedlák, František - Ulbrich, Karel - Strohalm, Jiří - Majer, Pavel - Šubr, Vladimír - Konvalinka, Jan
    iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties.
    Angewandte Chemie - International Edition. Roč. 55, č. 7 (2016), s. 2356-2360. ISSN 1433-7851. E-ISSN 1521-3773
    R&D Projects: GA ČR GBP208/12/G016; GA MŠMT LO1302
    Institutional support: RVO:61388963 ; RVO:61389013
    Keywords : antibody mimetics * HPMA * molecular recognition * polymer conjugates * protein targeting
    Subject RIV: CE - Biochemistry; CD - Macromolecular Chemistry (UMCH-V)
    Impact factor: 11.994, year: 2016
    http://onlinelibrary.wiley.com/doi/10.1002/anie.201508642/full
    Permanent Link: http://hdl.handle.net/11104/0259057
     
     
  9. 9.
    0428605 - ÚOCHB 2015 RIV US eng J - Journal Article
    Knedlík, Tomáš - Navrátil, Václav - Vik, V. - Pacík, D. - Šácha, Pavel - Konvalinka, Jan
    Detection and quantitation of glutamate carboxypeptidase II in human blood.
    Prostate. Roč. 74, č. 7 (2014), s. 768-780. ISSN 0270-4137. E-ISSN 1097-0045
    R&D Projects: GA ČR GAP304/12/0847
    Grant - others:OPPC(CZ) CZ.2.16/3.1.00/24016
    Institutional support: RVO:61388963
    Keywords : serum marker * glutamate carboxypeptidase II * plasma glutamate carboxypeptidase * prostate cancer * prostate-specific membrane antigen
    Subject RIV: CE - Biochemistry
    Impact factor: 3.565, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0233924
     
     
  10. 10.
    0377067 - ÚOCHB 2013 RIV US eng J - Journal Article
    Tykvart, Jan - Šácha, Pavel - Bařinka, Cyril - Knedlík, Tomáš - Starková, Jana - Lubkowski, J. - Konvalinka, Jan
    Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: Expression, characterization and structure analysis of recombinant human glutamate carboxypeptidase II.
    Protein Expression and Purification. Roč. 82, č. 1 (2012), s. 106-115. ISSN 1046-5928. E-ISSN 1096-0279
    R&D Projects: GA MŠMT 1M0508; GA MŠMT LC512
    Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520701
    Keywords : affinity purification * biotin acceptor peptide * recombinant protein expression * biotin-protein ligase (BirA) * co-localization * PSMA
    Subject RIV: CE - Biochemistry
    Impact factor: 1.429, year: 2012
    Permanent Link: http://hdl.handle.net/11104/0215606
     
     


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