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- 1.0454915 - ÚEB 2016 RIV GB eng J - Journal Article
Jorda, Radek - Schütznerová, E. - Cankař, P. - Brychtová, Veronika - Navrátilová, Jana - Kryštof, Vladimír
Novel arylazopyrazole inhibitors of cyclin-dependent kinases.
Bioorganic & Medicinal Chemistry. Roč. 23, č. 9 (2015), s. 1975-1981. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA14-19590S; GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : Cyclin-dependent kinases * Inhibitor * Cell cycle
Subject RIV: CE - Biochemistry
Impact factor: 2.923, year: 2015
Permanent Link: http://hdl.handle.net/11104/0255588File Download Size Commentary Version Access 2015_Jorda_BIOORGANIC & MEDICINAL CHEMISTRY_1975.pdf 3 1.3 MB Other open-access - 2.0433741 - ÚEB 2015 RIV GB eng J - Journal Article
Jorda, Radek - Navrátilová, Jana - Hušková, Zlata - Schütznerová, E. - Cankař, P. - Strnad, Miroslav - Kryštof, Vladimír
Arylazopyrazole AAP1742 Inhibits CDKs and Induces Apoptosis in Multiple Myeloma Cells via Mcl-1 Downregulation.
Chemical Biology & Drug Design. Roč. 84, č. 4 (2014), s. 402-408. ISSN 1747-0277. E-ISSN 1747-0285
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA14-19590S; GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : CAN508 * cyclin-dependent kinase * inhibitor
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.485, year: 2014
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=MEDLINE&DestLinkType=FullRecord&UT=24803299
Permanent Link: http://hdl.handle.net/11104/0237916File Download Size Commentary Version Access 2014_Jorda_CHEMICAL BIOLOGY & DRUG DESIGN_402.pdf 1 801.1 KB Other open-access - 3.0368592 - ÚEB 2012 RIV US eng J - Journal Article
Jorda, Radek - Havlíček, Libor - McNae, I. W. - Walkinshaw, M. D. - Voller, Jiří - Šturc, Antonín - Navrátilová, Jana - Kuzma, Marek - Mistrik, M. - Bártek, J. - Strnad, Miroslav - Kryštof, Vladimír
Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity.
Journal of Medicinal Chemistry. Roč. 54, č. 8 (2011), s. 2980-2993. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GA301/02/0475; GA ČR GA301/08/1649; GA MŠMT ED0007/01/01
Institutional research plan: CEZ:AV0Z50380511; CEZ:AV0Z50200510
Keywords : STRUCTURE-GUIDED DESIGN * DNA-END RESECTION * DOWN-REGULATION * R-ROSCOVITINE * CELL-CYCLE
Subject RIV: ED - Physiology
Impact factor: 5.248, year: 2011
Permanent Link: http://hdl.handle.net/11104/0202891File Download Size Commentary Version Access 2011_Jorda_JOURNAL OF MEDICINAL CHEMISTRY_2980.pdf 5 2.9 MB Other open-access