Search results
- 1.0493604 - ÚOCHB 2019 RIV DE eng J - Journal Article
Česnek, Michal - Skácel, Jan - Jansa, Petr - Dračínský, Martin - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Soto-Velasquez, M. - Watts, V. J. - Janeba, Zlatko
Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis.
ChemMedChem. Roč. 13, č. 17 (2018), s. 1779-1796. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046; GA ČR(CZ) GBP208/12/G016; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : adefovir * adenylate cyclase * Bacillus anthracis * Bordetella pertussis * inhibitors
OECD category: Organic chemistry
Impact factor: 3.016, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286939 - 2.0489553 - ÚOCHB 2019 RIV DE eng J - Journal Article
Frydrych, Jan - Skácel, Jan - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Dračínský, Martin - Gnanasekaran, Ramachandran - Lepšík, Martin - Soto-Velasquez, M. - Watts, V. J. - Janeba, Zlatko
Synthesis of alpha-Branched Acyclic Nucleoside Phosphonates as Potential Inhibitors of Bacterial Adenylate Cyclases.
ChemMedChem. Roč. 13, č. 2 (2018), s. 199-206. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046; GA ČR(CZ) GBP208/12/G016; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adenylate cyclase toxin * bisamidates * Bordetella pertussis * prodrugs
OECD category: Organic chemistry
Impact factor: 3.016, year: 2018
Permanent Link: http://hdl.handle.net/11104/0283953 - 3.0470846 - ÚOCHB 2017 RIV NL eng J - Journal Article
Jansa, Petr - Čechová, Lucie - Janeba, Zlatko
A complete degradation of organophosphates by microwave-assisted hydrolysis.
Current Microwave Chemistry. Roč. 3, č. 3 (2016), s. 219-226. ISSN 2213-3356
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : organophosphates * microwave irradiation * hydrolysis
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0268383 - 4.0467409 - ÚOCHB 2017 RIV DE eng J - Journal Article
Břehová, Petra - Šmídková, Markéta - Skácel, Jan - Dračínský, Martin - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, V. J. - Janeba, Zlatko
Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.
ChemMedChem. Roč. 11, č. 22 (2016), s. 2534-2546. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : adenylate cyclase toxin * acyclic nucleoside phosphonates * anthranilic acid
Subject RIV: CC - Organic Chemistry
Impact factor: 3.225, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265511 - 5.0458700 - ÚOCHB 2017 RIV FR eng J - Journal Article
Kaiser, Martin Maxmilian - Poštová Slavětínská, Lenka - Dračínský, Martin - Lee, Y. J. - Tian, Y. - Janeba, Zlatko
Synthesis and biological properties of prodrugs of (S)-3-(adenin-9-yl)-2-(phosphonomethoxy)propanoic acid.
European Journal of Medicinal Chemistry. Roč. 108, Jan 27 (2016), s. 374-380. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * (S)-CPMEA * antiviral * HCV * prodrugs
Subject RIV: CC - Organic Chemistry
Impact factor: 4.519, year: 2016
Permanent Link: http://hdl.handle.net/11104/0258949 - 6.0450219 - ÚOCHB 2016 RIV DE eng J - Journal Article
Kaiser, Martin Maxmilian - Hocková, Dana - Wang, T. H. - Dračínský, Martin - Poštová Slavětínská, Lenka - Procházková, Eliška - Edstein, M. D. - Chavchich, M. - Keough, D. T. - Guddat, L. W. - Janeba, Zlatko
Synthesis and Evaluation of Novel Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium falciparum and Human 6-Oxopurine Phosphoribosyltransferases.
ChemMedChem. Roč. 10, č. 10 (2015), s. 1707-1723. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046; GA ČR GAP207/11/0108
Institutional support: RVO:61388963
Keywords : 6-oxopurine * acyclic nucleoside phosphonates * phosphoribosyltransferases * malaria * phosphoramidates
Subject RIV: CC - Organic Chemistry
Impact factor: 2.980, year: 2015
Permanent Link: http://hdl.handle.net/11104/0251588 - 7.0448379 - ÚOCHB 2016 RIV GB eng J - Journal Article
Hřebabecký, Hubert - Procházková, Eliška - Šála, Michal - Plačková, Pavla - Tloušťová, Eva - Barauskas, O. - Lee, Y. J. - Tian, Y. - Mackman, R. - Nencka, Radim
Synthesis and biological evaluation of conformationally restricted adenine bicycloribonucleosides.
Organic & Biomolecular Chemistry. Roč. 13, č. 35 (2015), s. 9300-9313. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR GPP207/12/P625; GA ČR GA15-09310S; GA ČR GA13-24880S; GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : nucleic acid analogs * nucleoside triphosphates * sugar ring
Subject RIV: CC - Organic Chemistry
Impact factor: 3.559, year: 2015
http://pubs.rsc.org/en/content/articlepdf/2015/ob/c5ob00987a
Permanent Link: http://hdl.handle.net/11104/0250113 - 8.0446744 - ÚOCHB 2016 RIV DE eng J - Journal Article
Česnek, Michal - Jansa, Petr - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Dračínský, Martin - Brust, T. F. - Pávek, P. - Trejtnar, F. - Watts, V. J. - Janeba, Zlatko
Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis.
ChemMedChem. Roč. 10, č. 8 (2015), s. 1351-1364. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : adenylate cyclase toxin * bisamidates * Bordetella pertussis * nucleosides * phosphonates
Subject RIV: CC - Organic Chemistry
Impact factor: 2.980, year: 2015
Permanent Link: http://hdl.handle.net/11104/0248752 - 9.0445809 - ÚOCHB 2016 RIV US eng J - Journal Article
Eng, W. S. - Hocková, Dana - Špaček, Petr - Janeba, Zlatko - West, N. P. - Woods, K. - Naesens, L. M. J. - Keough, D. T. - Guddat, L. W.
First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity.
Journal of Medicinal Chemistry. Roč. 58, č. 11 (2015), s. 4822-4838. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GAP207/11/0108; GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : enzyme inhibitors * nucleotide analogues * tuberculosis * crystal structures
Subject RIV: CC - Organic Chemistry
Impact factor: 5.589, year: 2015
Permanent Link: http://hdl.handle.net/11104/0247858 - 10.0444646 - ÚOCHB 2016 RIV US eng J - Journal Article
Jansa, Petr - Holý, Antonín - Dračínský, Martin - Kolman, Viktor - Janeba, Zlatko - Kmoníčková, Eva - Zídek, Zdeněk
Synthesis and structure-activity relationship studies of polysubstituted pyrimidines as inhibitors of immune-activated nitric oxide production.
Medicinal Chemistry Research. Roč. 24, č. 5 (2015), s. 2154-2166. ISSN 1054-2523. E-ISSN 1554-8120
R&D Projects: GA ČR(CZ) GAP303/12/0172; GA MV VG20102015046
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : pyrimidine * nitric oxide * NO * anti-inflammatory
Subject RIV: CC - Organic Chemistry
Impact factor: 1.436, year: 2015
Permanent Link: http://hdl.handle.net/11104/0247170