Search results
- 1.0481195 - ÚOCHB 2018 CZ eng A - Abstract
Česnek, Michal - Dračínský, Martin - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, V. J. - Janeba, Zlatko
Synthesis and evaluation of novel acyclic nucleoside phosphonates with unnatural nucleobases as potent inhibitors of Bordetella pertussis adenylate cyclase toxin.
SCNAC 2017. 17th Symposium on Chemistry of Nucleic Acid Components. Praha: Confis Conference, 2017. s. 128.
[SCNAC 2017. Symposium on Chemistry of Nucleic Acid Components /17./. 04.06.2017-09.06.2017, Český Krumlov]
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates (ANPs) * adenylate cyclase toxin (ACT) * Bordetella pertussis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0276795 - 2.0481189 - ÚOCHB 2018 CZ eng A - Abstract
Břehová, Petra - Šmídková, Markéta - Skácel, Jan - Dračínský, Martin - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, V. J. - Janeba, Zlatko
Synthesis of acyclic nucleoside phosphonates with unnatural heterocyclic bases bearing aryl substituents and their inhibitory activity towards bacterial and human adenylate cyclases.
SCNAC 2017. 17th Symposium on Chemistry of Nucleic Acid Components. Praha: Confis Conference, 2017. s. 125.
[SCNAC 2017. Symposium on Chemistry of Nucleic Acid Components /17./. 04.06.2017-09.06.2017, Český Krumlov]
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates (ANPs) * adenylate cyclase toxin (ACT) * Bordetella pertussis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0276789 - 3.0465007 - ÚOCHB 2017 NL eng A - Abstract
Frydrych, Jan - Dračínský, Martin - Gnanasekaran, Ramachandran - Lepšík, Martin - Šmídková, Markéta - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Janeba, Zlatko
Novel adenine acyclic nucleoside phosphonates and their derivatives as potent inhibitors of bacterial adenylate cyclases.
ECHC 2016. 27th European Colloquium on Heterocyclic Chemistry. Amsterdam: -, 2016.
[ECHC 2016. European Colloquium on Heterocyclic Chemistry /27./. 03.07.2016-06.07.2016, Amsterdam]
R&D Projects: GA MV VG20102015046; GA ČR(CZ) GBP208/12/G016; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : acyclic nuceloside phosphonates * bacterial adenylate cyclases
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0263730 - 4.0464964 - ÚOCHB 2017 ES eng A - Abstract
Česnek, Michal - Šmídková, Markéta - Dračínský, Martin - Janeba, Zlatko
Novel acyclic nucleoside phosphonates containing unnatural nucleobases as potent inhibitors of Bordetella pertussis adenylyl cyclase toxin.
17th Tetrahedron Symposium. Challenges in Biological, Bioorganic, Organic and Medicinal Chemistry. Sitges: Elsevier, 2016.
[Tetrahedron Symposium. Challenges in Biological, Bioorganic, Organic and Medicinal Chemistry /17./. 28.06.2016-01.07.2016, Sitges]
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates (ANPs) * adenylate cyclase toxin (ACT) * Bordetella pertussis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0263704 - 5.0464963 - ÚOCHB 2017 ES eng A - Abstract
Břehová, Petra - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Skácel, Jan - Dračínský, Martin - Janeba, Zlatko
Synthesis of acyclic nucleoside phosphonates bearing aryl substituent at the acyclic linker as potential inhibitors of adenylate cyclase toxin from Bordetella pertussis.
17th Tetrahedron Symposium. Challenges in Biological, Bioorganic, Organic and Medicinal Chemistry. Sitges: Elsevier, 2016.
[Tetrahedron Symposium. Challenges in Biological, Bioorganic, Organic and Medicinal Chemistry /17./. 28.06.2016-01.07.2016, Sitges]
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates (ANPs) * adenylate cyclase toxin (ACT) * Bordetella pertussis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0263697 - 6.0454985 - ÚOCHB 2016 CU eng A - Abstract
Janeba, Zlatko
Novel types of acyclic nucleoside phosphonates: Chemistry and biology.
Quimicuba 2015. 9th Congress of Chemical Sciences, Technology and Innovation. La Habana: Cuban Chemical Society, 2015. LO009.
[Quimicuba 2015. Congress of Chemical Sciences, Technology and Innovation /9./. 13.10.2015-16.10.2015, La Habana]
R&D Projects: GA ČR GAP207/11/0108; GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * malaria * tuberculosis * inhibitors * 6-oxopurine phosphoribosyltransferases
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0255646 - 7.0454982 - ÚOCHB 2016 US eng A - Abstract
Janeba, Zlatko - Čechová, Lucie - Procházková, Eliška - Dračínský, Martin
Is 'planamerism' a novel stereochemical phenomenon?
FloHet-2015. 16th Florida Heterocyclic and Synthetic Conference. Gainesville: ARKAT USA, 2015. s. 98.
[FloHet-2015. Florida Heterocyclic and Synthetic Conference /16./. 01.03.2015-04.03.2015, Gainesville]
R&D Projects: GA ČR GA15-11223S; GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : pyrimidine * intramolecular hydrogen bonding * planamerism * rotational barrier
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0255644 - 8.0454280 - ÚOCHB 2016 CZ eng A - Abstract
Čechová, Lucie - Procházková, Eliška - Dračínský, Martin - Janeba, Zlatko
Study of rotational barriers in 5-nitrosopyrimidines.
Liblice 2015. 50th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2015. s. 64.
[Liblice 2015. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /50./. 06.11.2015-08.11.2015, Olomouc]
R&D Projects: GA MV VG20102015046; GA ČR GA15-11223S
Institutional support: RVO:61388963
Keywords : pyrimidine * intramolecular hydrogen bonding * rotational barrier
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0256231 - 9.0454279 - ÚOCHB 2016 CZ eng A - Abstract
Břehová, Petra - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Dračínský, Martin - Janeba, Zlatko
Synthesis of acyclic nucleoside phosphonates bearing (N-methyl)anthraniloyl substituent as potential inhibitors of adenylate cyclase toxin from Bordetella Pertussis.
Liblice 2015. 50th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2015. s. 61.
[Liblice 2015. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /50./. 06.11.2015-08.11.2015, Olomouc]
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adenylate cyclase toxin * prodrugs
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0256230 - 10.0451346 - ÚOCHB 2016 SI eng A - Abstract
Šolínová, Veronika - Mikysková, Hana - Kaiser, Martin Maxmilian - Janeba, Zlatko - Holý, Antonín - Kašička, Václav
Affinity capillary electrophoresis applied to investigation of complexes of acyclic nucleoside phosphonates with beta-cyclodextrin.
ISSS 2015. 21st International Symposium on Separation Sciences. Ljubljana: National Institute of Chemistry, 2015 - (Vovk, I.; Glavnik, V.; Albreht, A.). s. 127. ISBN 978-961-6104-28-9.
[ISSS 2015. International Symposium on Separation Sciences /21./. 30.06.2015-03.07.2015, Ljubljana]
R&D Projects: GA ČR(CZ) GA13-17224S; GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * complexes * capillary electrophoresis
Subject RIV: CB - Analytical Chemistry, Separation
Permanent Link: http://hdl.handle.net/11104/0252524