Search results
- 1.0461356 - ÚOCHB 2017 RIV US eng J - Journal Article
Perlíková, Pavla - Rylová, G. - Nauš, Petr - Elbert, Tomáš - Tloušťová, Eva - Bourderioux, Aurelie - Poštová Slavětínská, Lenka - Motyka, K. - Doležal, D. - Znojek, P. - Nová, A. - Harvanová, M. - Džubák, P. - Šiller, M. - Hlaváč, J. - Hajdúch, M. - Hocek, Michal
7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action.
Molecular Cancer Therapeutics. Roč. 15, č. 5 (2016), s. 922-937. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR GAP207/11/0344; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : sugar-modified derivatives * cross-coupling reactions * ribosomal RNA synthesis
Subject RIV: CC - Organic Chemistry
Impact factor: 5.764, year: 2016
Permanent Link: http://hdl.handle.net/11104/0260969 - 2.0459237 - ÚOCHB 2017 RIV DE eng J - Journal Article
Sabat, Nazarii - Nauš, Petr - Matyašovský, Ján - Dziuba, Dmytro - Poštová Slavětínská, Lenka - Hocek, Michal
Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki-Miyaura Cross-Coupling Reactions.
Synthesis. Roč. 48, č. 7 (2016), s. 1029-1045. ISSN 0039-7881. E-ISSN 1437-210X
R&D Projects: GA ČR GAP207/11/0344
Institutional support: RVO:61388963
Keywords : nucleobases * deazapurines * pyrrolo[2,3-d]pyrimidines * Suzuki cross-coupling * arylation
Subject RIV: CC - Organic Chemistry
Impact factor: 2.650, year: 2016
Permanent Link: http://hdl.handle.net/11104/0259468 - 3.0454255 - ÚOCHB 2016 RIV DE eng J - Journal Article
Tokarenko, Anna - Poštová Slavětínská, Lenka - Klepetářová, Blanka - Hocek, Michal
Synthesis of Benzene and Pyridine 2-C-Methyl-C-ribonucleosides and -nucleotides.
European Journal of Organic Chemistry. Roč. 2015, č. 36 (2015), s. 7962-7983. ISSN 1434-193X. E-ISSN 1099-0690
R&D Projects: GA ČR GAP207/11/0344
Institutional support: RVO:61388963
Keywords : nucleosides * nucleotides * glycosides * antiviral agents * cross-coupling
Subject RIV: CC - Organic Chemistry
Impact factor: 3.068, year: 2015
Permanent Link: http://hdl.handle.net/11104/0254984 - 4.0454134 - ÚOCHB 2016 RIV GB eng J - Journal Article
Nauš, Petr - Caletková, Olga - Perlíková, Pavla - Poštová Slavětínská, Lenka - Tloušťová, Eva - Hodek, Jan - Weber, Jan - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and biological profiling of 6-or 7-(het)aryl-7-deazapurine 4 '-C-methylribonucleosides.
Bioorganic & Medicinal Chemistry. Roč. 23, č. 23 (2015), s. 7422-7438. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA ČR GAP207/11/0344
Institutional support: RVO:61388963
Keywords : nucleosides * 4 '-C-methyl-ribonucleosides * branched nucleosides * nucleoside antivirals * prodrugs
Subject RIV: CC - Organic Chemistry
Impact factor: 2.923, year: 2015
Permanent Link: http://hdl.handle.net/11104/0254834 - 5.0450014 - ÚOCHB 2016 RIV US eng J - Journal Article
Downey, Alan Michael - Richter, C. - Pohl, Radek - Mahrwald, R. - Hocek, Michal
Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose.
Organic Letters. Roč. 17, č. 18 (2015), s. 4604-4607. ISSN 1523-7060. E-ISSN 1523-7052
R&D Projects: GA ČR GAP207/11/0344
Institutional support: RVO:61388963
Keywords : nucleosides * cytostatics * biological activity
Subject RIV: CC - Organic Chemistry
Impact factor: 6.732, year: 2015
http://pubs.acs.org/doi/pdf/10.1021/acs.orglett.5b02332
Permanent Link: http://hdl.handle.net/11104/0251424File Download Size Commentary Version Access 0450014.pdf 6 1 MB Publisher’s postprint open-access - 6.0445290 - ÚOCHB 2016 RIV DE eng J - Journal Article
Malnuit, Vincent - Poštová Slavětínská, Lenka - Nauš, Petr - Džubák, P. - Hajdúch, M. - Stolaříková, J. - Snášel, Jan - Pichová, Iva - Hocek, Michal
2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.
ChemMedChem. Roč. 10, č. 6 (2015), s. 1079-1093. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA ČR GAP207/11/0344; GA MŠMT(CZ) LO1304; GA MŠMT LO1302; GA TA ČR(CZ) TE01020028
EU Projects: European Commission(XE) 241587 - SYSTEMTB
Institutional support: RVO:61388963
Keywords : antimycobacterial agents * cytostatics * nucleosides * purines * pyrrolopyrimidines
Subject RIV: CC - Organic Chemistry
Impact factor: 2.980, year: 2015
Permanent Link: http://hdl.handle.net/11104/0247636 - 7.0436116 - ÚOCHB 2015 RIV US eng J - Journal Article
Snášel, Jan - Nauš, Petr - Dostál, Jiří - Hnízda, Aleš - Fanfrlík, Jindřich - Brynda, Jiří - Bourderioux, Aurelie - Dušek, Michal - Dvořáková, H. - Stolaříková, J. - Zábranská, Helena - Pohl, Radek - Konečný, P. - Džubák, P. - Votruba, Ivan - Hajdúch, M. - Řezáčová, Pavlína - Veverka, Václav - Hocek, Michal - Pichová, Iva
Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 57, č. 20 (2014), s. 8268-8279. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GAP207/11/0344; GA MŠMT LO1302; GA MŠMT(CZ) LK11205
EU Projects: European Commission(XE) 241587 - SYSTEMTB
Grant - others:GA MŠk(CZ) LM2011020
Institutional support: RVO:61388963 ; RVO:68378271
Keywords : 7-(het)aryl-7-deazaadenine ribonucleosides * enzyme inhibition * adenosine kinase * cytostatic activity
Subject RIV: CC - Organic Chemistry
Impact factor: 5.447, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239959 - 8.0427678 - ÚOCHB 2015 RIV US eng J - Journal Article
Nauš, Petr - Caletková, Olga - Konečný, P. - Džubák, P. - Bogdanová, K. - Kolář, M. - Vrbková, J. - Slavětínská, Lenka - Tloušťová, Eva - Perlíková, Pavla - Hajdúch, M. - Hocek, Michal
Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 57, č. 3 (2014), s. 1097-1110. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GAP207/11/0344; GA TA ČR(CZ) TE01020028
Grant - others:Operational Programme Research and Development for Innovations(XE) CZ.1.05/2.1.00/01.0030
Institutional support: RVO:61388963
Keywords : adenosine-kinase-inhibitors * cross-coupling reactions * cytotoxic nucleoside analogs
Subject RIV: CC - Organic Chemistry
Impact factor: 5.447, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233200 - 9.0399777 - ÚOCHB 2014 RIV GB eng J - Journal Article
Perlíková, Pavla - Konečný, P. - Nauš, Petr - Snášel, Jan - Votruba, Ivan - Džubák, P. - Pichová, Iva - Hajdúch, M. - Hocek, Michal
6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents.
MedChemComm. Roč. 4, č. 11 (2013), s. 1497-1500. ISSN 2040-2503. E-ISSN 2040-2511
R&D Projects: GA ČR GAP207/11/0344
EU Projects: European Commission(XE) 241587 - SYSTEMTB
Grant - others:Operational Programme Research and Development for Innovations(XE) CZ.1.05/2.1.00/01.0030
Institutional support: RVO:61388963
Keywords : mycobacterium-tuberculosis * enzyme-inhibition * 6-(het)aryl-7-deazapurine ribonucleosides
Subject RIV: CC - Organic Chemistry
Impact factor: 2.626, year: 2013
Permanent Link: http://hdl.handle.net/11104/0227143 - 10.0396348 - ÚOCHB 2014 RIV GB eng J - Journal Article
Kubelka, Tomáš - Slavětínská, Lenka - Eigner, Václav - Hocek, Michal
Synthesis of 2,6-disubstituted pyridin-3-yl C-2 '-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides.
Organic & Biomolecular Chemistry. Roč. 11, č. 28 (2013), s. 4702-4718. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR GAP207/11/0344
Institutional support: RVO:61388963
Keywords : aryl halides * base-pair * DNA * replication * amination
Subject RIV: CC - Organic Chemistry
Impact factor: 3.487, year: 2013
Permanent Link: http://hdl.handle.net/11104/0224213