Search results
- 1.0568174 - ÚOCHB 2024 RIV US eng J - Journal Article
Prener, Ladislav - Baszczyňski, Ondřej - Kaiser, Martin Maxmilian - Dračínský, Martin - Stepan, G. - Lee, Y. J. - Brumshtein, B. - Yu, H. - Jansa, P. - Lansdon, E. B. - Janeba, Zlatko
Design and Synthesis of Novel HIV-1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties.
Journal of Medicinal Chemistry. Roč. 66, č. 3 (2023), s. 1761-1777. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:61388963
Keywords : reverse transcriptase inhibitors * wild type * optimization
OECD category: Organic chemistry
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.2c01574
Permanent Link: https://hdl.handle.net/11104/0339509 - 2.0543611 - ÚOCHB 2022 RIV US eng J - Journal Article
Pimková Polidarová, Markéta - Břehová, Petra - Kaiser, Martin Maxmilian - Smola, Miroslav - Dračínský, Martin - Smith, Joshua - Marek, Aleš - Dejmek, Milan - Šála, Michal - Gutten, Ondrej - Rulíšek, Lubomír - Novotná, Barbora - Brázdová, Andrea - Janeba, Zlatko - Nencka, Radim - Bouřa, Evžen - Páv, Ondřej - Birkuš, Gabriel
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP).
Journal of Medicinal Chemistry. Roč. 64, č. 11 (2021), s. 7596-7616. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-08772S
Institutional support: RVO:61388963
Keywords : DNA sensor * interferon genes * cyclic GMP-AMP
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acs.jmedchem.1c00301
Permanent Link: http://hdl.handle.net/11104/0320799 - 3.0533528 - ÚOCHB 2021 RIV US eng J - Journal Article
Dosoudil, P. - Kotek, V. - Kolman, Viktor - Baszczyňski, Ondřej - Kaiser, Martin Maxmilian - Janeba, Zlatko - Havránek, M.
Development of Scalable Synthesis of 5-Butyl-4-(4-methoxyphenyl)-6-phenylpyrimidin-2-amine (WQE-134), a Dual Inhibitor of Nitric Oxide and Prostaglandin E2 Production.
Organic Process Research & Development. Roč. 24, č. 9 (2020), s. 1718-1724. ISSN 1083-6160. E-ISSN 1520-586X
R&D Projects: GA TA ČR(CZ) TE01020028
Institutional support: RVO:61388963
Keywords : pyrimidines * Eaton’s reagent * upscale * C-acylation
OECD category: Organic chemistry
Impact factor: 3.317, year: 2020
Method of publishing: Limited access
https://doi.org/10.1021/acs.oprd.0c00324
Permanent Link: http://hdl.handle.net/11104/0312366 - 4.0500199 - ÚOCHB 2019 RIV GB eng J - Journal Article
Baszczyňski, Ondřej - Kaiser, Martin Maxmilian - Česnek, Michal - Břehová, Petra - Jansa, Petr - Procházková, Eliška - Dračínský, Martin - Snoeck, R. - Andrei, G. - Janeba, Zlatko
Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus.
Antiviral Chemistry and Chemotherapy. Roč. 26, Nov 29 (2018), s. 1-13. ISSN 0956-3202
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * xanthine * PMEX * antiviral * HCMV * VZV
OECD category: Organic chemistry
https://journals.sagepub.com/doi/10.1177/2040206618813050
Permanent Link: http://hdl.handle.net/11104/0292843 - 5.0495572 - ÚOCHB 2019 RIV DE eng J - Journal Article
Kaiser, Martin Maxmilian - Novák, Pavel - Rosenbergová, Šárka - Poštová Slavětínská, Lenka - Rosenberg, Ivan - Janeba, Zlatko
Acyclic Nucleoside Phosphonates Bearing (R)- or (S)-9-[3-Hydroxy-2-(phosphonoethoxy)propyl] (HPEP) Moiety as Monomers for the Synthesis of Modified Oligonucleotides.
European Journal of Organic Chemistry. Roč. 2018, č. 37 (2018), s. 5119-5126. ISSN 1434-193X. E-ISSN 1099-0690
Institutional support: RVO:61388963
Keywords : nucleobases * oligonucleotides * nonamers * duplexes * hybridization * Tm values
OECD category: Organic chemistry
Impact factor: 3.029, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288521 - 6.0478407 - ÚOCHB 2018 RIV DE eng J - Journal Article
Kaiser, Martin Maxmilian - Baszczyňski, Ondřej - Hocková, Dana - Poštová Slavětínská, Lenka - Dračínský, Martin - Keough, D. T. - Guddat, L. W. - Janeba, Zlatko
Acyclic Nucleoside Phosphonates Containing 9-Deazahypoxanthine and a Five-Membered Heterocycle as Selective Inhibitors of Plasmodial 6-Oxopurine Phosphoribosyltransferases.
ChemMedChem. Roč. 12, č. 14 (2017), s. 1133-1141. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA ČR(CZ) GA16-06049S
Institutional support: RVO:61388963
Keywords : inhibitors * nucleosides * malaria * phosphonates * purine salvage
OECD category: Organic chemistry
Impact factor: 3.009, year: 2017
Permanent Link: http://hdl.handle.net/11104/0274530 - 7.0458700 - ÚOCHB 2017 RIV FR eng J - Journal Article
Kaiser, Martin Maxmilian - Poštová Slavětínská, Lenka - Dračínský, Martin - Lee, Y. J. - Tian, Y. - Janeba, Zlatko
Synthesis and biological properties of prodrugs of (S)-3-(adenin-9-yl)-2-(phosphonomethoxy)propanoic acid.
European Journal of Medicinal Chemistry. Roč. 108, Jan 27 (2016), s. 374-380. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * (S)-CPMEA * antiviral * HCV * prodrugs
Subject RIV: CC - Organic Chemistry
Impact factor: 4.519, year: 2016
Permanent Link: http://hdl.handle.net/11104/0258949 - 8.0458609 - ÚOCHB 2017 RIV DE eng J - Journal Article
Šolínová, Veronika - Mikysková, Hana - Kaiser, Martin Maxmilian - Janeba, Zlatko - Holý, Antonín - Kašička, Václav
Estimation of apparent binding constant of complexes of selected acyclic nucleoside phosphonates with beta-cyclodextrin by affinity capillary electrophoresis.
Electrophoresis. Roč. 37, č. 2 (2016), s. 239-247. ISSN 0173-0835. E-ISSN 1522-2683
R&D Projects: GA ČR(CZ) GA13-17224S; GA ČR(CZ) GA15-01948S
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * affinity capillary electrophoresis * binding constant * nucleotide analogs * beta-cyclodextrin
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 2.744, year: 2016
Permanent Link: http://hdl.handle.net/11104/0258855 - 9.0450219 - ÚOCHB 2016 RIV DE eng J - Journal Article
Kaiser, Martin Maxmilian - Hocková, Dana - Wang, T. H. - Dračínský, Martin - Poštová Slavětínská, Lenka - Procházková, Eliška - Edstein, M. D. - Chavchich, M. - Keough, D. T. - Guddat, L. W. - Janeba, Zlatko
Synthesis and Evaluation of Novel Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium falciparum and Human 6-Oxopurine Phosphoribosyltransferases.
ChemMedChem. Roč. 10, č. 10 (2015), s. 1707-1723. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MV VG20102015046; GA ČR GAP207/11/0108
Institutional support: RVO:61388963
Keywords : 6-oxopurine * acyclic nucleoside phosphonates * phosphoribosyltransferases * malaria * phosphoramidates
Subject RIV: CC - Organic Chemistry
Impact factor: 2.980, year: 2015
Permanent Link: http://hdl.handle.net/11104/0251588 - 10.0429522 - ÚOCHB 2015 RIV DE eng J - Journal Article
Šolínová, Veronika - Kaiser, Martin Maxmilian - Lukáč, Miloš - Janeba, Zlatko - Kašička, Václav
Enantiopurity analysis of new types of acyclic nucleoside phosphonates by capillary electrophoresis with cyclodextrins as chiral selectors.
Journal of Separation Science. Roč. 37, č. 3 (2014), s. 295-303. ISSN 1615-9306. E-ISSN 1615-9314
R&D Projects: GA ČR(CZ) GAP206/12/0453; GA ČR(CZ) GA13-17224S; GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * CE * chiral analysis * cyclodextrins * nucleotide analogs
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 2.737, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234687