Search results
- 1.0463915 - MBÚ 2017 RIV NL eng J - Journal Article
Tomalová, Barbora - Šírová, Milada - Rossmann, Pavel - Pola, Robert - Strohalm, Jiří - Chytil, Petr - Černý, Viktor - Tomala, Jakub - Kabešová, Martina - Říhová, Blanka - Ulbrich, Karel - Etrych, Tomáš - Kovář, Marek
The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.
Journal of Controlled Release. Roč. 223, 10 February (2016), s. 1-10. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR(CZ) GAP301/11/0325; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : HPMA * Doxorubicin * Structure
Subject RIV: EE - Microbiology, Virology; CD - Macromolecular Chemistry (UMCH-V)
Impact factor: 7.786, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263061 - 2.0441077 - MBÚ 2015 RIV NL eng J - Journal Article
Votavová, Petra - Tomala, Jakub - Kovář, Marek
Increasing the biological activity of IL-2 and IL-15 through complexing with anti-IL-2 mAbs and Il-15Ralfa-Fc chimera.
Immunology Letters. Roč. 195, č. 1 (2014), s. 1-10. ISSN 0165-2478. E-ISSN 1879-0542
R&D Projects: GA ČR GAP301/11/0325; GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR GA13-12885S
Institutional support: RVO:61388971
Keywords : IL-2 * IL-15 * chimera
Subject RIV: EC - Immunology
Impact factor: 2.512, year: 2014
Permanent Link: http://hdl.handle.net/11104/0244107 - 3.0439488 - ÚMCH 2015 RIV GB eng J - Journal Article
Etrych, Tomáš - Strohalm, Jiří - Šírová, Milada - Tomalová, Barbora - Rossmann, Pavel - Říhová, Blanka - Ulbrich, Karel - Kovář, Marek
High-molecular weight star conjugates containing docetaxel with high anti-tumor activity and low systemic toxicity in vivo.
Polymer Chemistry. Roč. 6, č. 1 (2015), s. 160-170. ISSN 1759-9954. E-ISSN 1759-9962
R&D Projects: GA ČR GAP301/11/0325; GA ČR GCP207/12/J030; GA MŠMT(CZ) EE2.3.20.0055
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : star polymer * HPMA copolymers * docetaxel
Subject RIV: CD - Macromolecular Chemistry; EC - Immunology (MBU-M)
Impact factor: 5.687, year: 2015
Permanent Link: http://hdl.handle.net/11104/0244872 - 4.0435908 - MBÚ 2015 RIV US eng J - Journal Article
Adkins, Irena - Kamanová, Jana - Kocourková, A. - Švédová, Martina - Tomala, Jakub - Janová, H. - Mašín, Jiří - Chládková, Barbara - Bumba, Ladislav - Kovář, Marek - Ross, P. J. - Tučková, Ludmila - Spíšek, R. - Mills, K. H. G. - Šebo, Peter
Bordetella Adenylate Cyclase Toxin Differentially Modulates Toll-Like Receptor-Stimulated Activation, Migration and T Cell Stimulatory Capacity of Dendritic Cells.
PLoS ONE. Roč. 9, č. 8 (2014). ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR GA310/08/0447; GA ČR GP310/09/P582; GA ČR GAP301/11/0325; GA MŠMT 1M0506
Institutional support: RVO:61388971
Keywords : RESPIRATORY-INFECTION * INTERLEUKIN-10 PRODUCTION * PROTECTIVE IMMUNITY
Subject RIV: EE - Microbiology, Virology
Impact factor: 3.234, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239791File Download Size Commentary Version Access Adkins_2014_journal.pone.0104064.pdf 5 1.8 MB Publisher’s postprint open-access - 5.0427397 - ÚMCH 2015 RIV NL eng J - Journal Article
Etrych, Tomáš - Šubr, Vladimír - Laga, Richard - Říhová, Blanka - Ulbrich, Karel
Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: impact of the carrier structure onto synergistic action in the treatment of solid tumours.
European Journal of Pharmaceutical Sciences. Roč. 58, 16 July (2014), s. 1-12. ISSN 0928-0987. E-ISSN 1879-0720
R&D Projects: GA ČR GAP301/11/0325; GA MŠMT EE2.3.30.0029; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : HPMA copolymer * synergistic effect * doxorubicin
Subject RIV: CE - Biochemistry; FD - Oncology ; Hematology (MBU-M)
Impact factor: 3.350, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234394 - 6.0421776 - ÚMCH 2014 RIV DE eng J - Journal Article
Kostková, Hana - Etrych, Tomáš - Říhová, Blanka - Kostka, Libor - Starovoytova, Larisa - Kovář, Marek - Ulbrich, Karel
HPMA copolymer conjugates of DOX and mitomycin C for combination therapy: physicochemical characterization, cytotoxic effects, combination index analysis, and anti-tumor efficacy.
Macromolecular Bioscience. Roč. 13, č. 12 (2013), s. 1648-1660. ISSN 1616-5187. E-ISSN 1616-5195
R&D Projects: GA ČR GAP301/11/0325; GA MŠMT EE2.3.30.0029
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : doxorubicin * HPMA copolymers * mitomycin C
Subject RIV: CE - Biochemistry; FD - Oncology ; Hematology (MBU-M)
Impact factor: 3.650, year: 2013
Permanent Link: http://hdl.handle.net/11104/0228061 - 7.0399622 - MBÚ 2014 RIV US eng J - Journal Article
Tomala, Jakub - Kovářová, Jiřina - Kabešová, Martina - Votavová, Petra - Chmelová, Helena - Dvořáková, Barbora - Říhová, Blanka - Kovář, Marek
Chimera of IL-2 Linked to Light Chain of anti-IL-2 mAb Mimics IL-2/anti-IL-2 mAb Complexes Both Structurally and Functionally.
ACS Chemical Biology. Roč. 8, č. 5 (2013), s. 871-876. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA ČR GAP301/11/0325
Institutional support: RVO:61388971
Keywords : IN-VIVO EXPANSION * IL-2 * ANTIBODY
Subject RIV: CE - Biochemistry
Impact factor: 5.356, year: 2013
Permanent Link: http://hdl.handle.net/11104/0227039 - 8.0390945 - ÚMCH 2014 RIV US eng J - Journal Article
Pola, Robert - Laga, Richard - Ulbrich, Karel - Sieglová, Irena - Král, Vlastimil - Fábry, Milan - Kabešová, Martina - Kovář, Marek - Pechar, Michal
Polymer therapeutics with a coiled coil motif targeted against murine BCL1 leukemia.
Biomacromolecules. Roč. 14, č. 3 (2013), s. 881-889. ISSN 1525-7797. E-ISSN 1526-4602
R&D Projects: GA ČR GAP301/11/0325; GA AV ČR IAAX00500803
Institutional research plan: CEZ:AV0Z50520514
Institutional support: RVO:61389013 ; RVO:61388971 ; RVO:68378050
Keywords : coiled coil * polymer therapeutics * scFv
Subject RIV: CD - Macromolecular Chemistry; EC - Immunology (MBU-M); EB - Genetics ; Molecular Biology (UMG-J)
Impact factor: 5.788, year: 2013
Permanent Link: http://hdl.handle.net/11104/0220758 - 9.0388377 - ÚMCH 2013 RIV US eng J - Journal Article
Kunjachan, S. - Gremse, F. - Theek, B. - Koczera, P. - Pola, Robert - Pechar, Michal - Etrych, Tomáš - Ulbrich, Karel - Storm, G. - Kiessling, F. - Lammers, T.
Noninvasive optical imaging of nanomedicine biodistribution.
ACS Nano. Roč. 7, č. 1 (2013), s. 252-262. ISSN 1936-0851. E-ISSN 1936-086X
R&D Projects: GA ČR GAP301/11/0325
Institutional research plan: CEZ:AV0Z40500505
Institutional support: RVO:61389013
Keywords : nanomedicine * drug targeting * biodistribution
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 12.033, year: 2013
Permanent Link: http://hdl.handle.net/11104/0217433 - 10.0384103 - ÚMCH 2013 RIV GB eng J - Journal Article
Talelli, M. - Oliveira, S. - Rijcken, C. J. F. - Pieters, E. H. E. - Etrych, Tomáš - Ulbrich, Karel - van Nostrum, R. C. F. - Storm, G. - Hennink, W. E. - Lammers, T.
Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy.
Biomaterials. Roč. 34, č. 4 (2013), s. 1255-1260. ISSN 0142-9612. E-ISSN 1878-5905
R&D Projects: GA AV ČR IAA400500806; GA ČR GAP301/11/0325
Institutional research plan: CEZ:AV0Z40500505
Keywords : polymeric micelle * doxorubicin * active targeting
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 8.312, year: 2013
Permanent Link: http://hdl.handle.net/11104/0217252