Search results
- 1.0490865 - FGÚ 2019 RIV JP eng J - Journal Article
Hahnová, K. - Brabcová, I. - Neckář, Jan - Weissová, Romana - Svatoňová, Anna - Nováková, O. - Žurmanová, J. - Kalous, M. - Šilhavý, Jan - Pravenec, Michal - Kolář, František - Novotný, J.
beta-Adrenergic signaling, monoamine oxidase A and antioxidant defence in the myocardium of SHR and SHR-mtBN conplastic rat strains: the effect of chronic hypoxia.
Journal of Physiological Sciences. Roč. 68, č. 4 (2018), s. 441-454. ISSN 1880-6546. E-ISSN 1880-6562
R&D Projects: GA ČR(CZ) GA13-10267S; GA MŠMT(CZ) LL1204; GA ČR(CZ) GAP301/12/0696
Institutional support: RVO:67985823
Keywords : SHR * mitochondrial genome * myocardium * beta-adrenergic receptors * adenylyl cyclase * monoamine oxidase A * antioxidant defence * chronic hypoxia
OECD category: Physiology (including cytology)
Impact factor: 3.341, year: 2018 ; AIS: 0.553, rok: 2018
DOI: https://doi.org/10.1007/s12576-017-0546-8
Permanent Link: http://hdl.handle.net/11104/0284995 - 2.0484402 - FGÚ 2018 RIV US eng J - Journal Article
Pecinová, Alena - Drahota, Zdeněk - Kovalčíková, Jana - Kovářová, Nikola - Pecina, Petr - Alán, Lukáš - Zima, Michal - Houštěk, Josef - Mráček, Tomáš
Pleiotropic Effects of Biguanides on Mitochondrial Reactive Oxygen Species Production.
Oxidative Medicine and Cellular Longevity. Roč. 2017, č. 2017 (2017), č. článku 7038603. ISSN 1942-0900. E-ISSN 1942-0994
R&D Projects: GA ČR(CZ) GA16-12726S; GA MŠMT(CZ) LL1204
Institutional support: RVO:67985823
Keywords : brown adipose tissue * mitochondria * respiratory chain oxidoreductases * mitochondrial glycerophosphate dehydrogenase * superoxide production * biguanides * metformin
OECD category: Biochemistry and molecular biology
Impact factor: 4.936, year: 2017 ; AIS: 1.115, rok: 2017
DOI: https://doi.org/10.1155/2017/7038603
Permanent Link: http://hdl.handle.net/11104/0279565 - 3.0474947 - FGÚ 2018 RIV US eng J - Journal Article
Liška, F. - Landa, Vladimír - Zídek, Václav - Mlejnek, Petr - Šilhavý, Jan - Šimáková, Miroslava - Strnad, Hynek - Trnovská, J. - Škop, V. - Kazdová, L. - Starker, C.G. - Voytas, D.F. - Izsvák, Z. - Mancini, M. - Šeda, O. - Křen, V. - Pravenec, Michal
Downregulation of Plzf Gene Ameliorates Metabolic and Cardiac Traits in the Spontaneously Hypertensive Rat.
Hypertension. Roč. 69, č. 6 (2017), s. 1084-1091. ISSN 0194-911X. E-ISSN 1524-4563
R&D Projects: GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204
Institutional support: RVO:67985823 ; RVO:68378050
Keywords : fibrosis * hypertension * hypertrophy * left ventricular rats * inbred * SHR * transcriptome
OECD category: Cardiac and Cardiovascular systems; Cardiac and Cardiovascular systems (UMG-J)
Impact factor: 6.823, year: 2017 ; AIS: 2.188, rok: 2017
DOI: https://doi.org/10.1161/HYPERTENSIONAHA.116.08798
Permanent Link: http://hdl.handle.net/11104/0271844 - 4.0474681 - FGÚ 2018 RIV GB eng J - Journal Article
Neckář, Jan - Svatoňová, Anna - Weissová, Romana - Drahota, Zdeněk - Zajíčková, Pavlína - Brabcová, I. - Kolář, D. - Alánová, Petra - Vašinová, Jana - Šilhavý, Jan - Hlaváčková, Markéta - Tauchmannová, Kateřina - Milerová, Marie - Ošťádal, Bohuslav - Červenka, L. - Žurmanová, J. - Kalous, M. - Nováková, Olga - Novotný, J. - Pravenec, Michal - Kolář, František
Selective replacement of mitochondrial DNA increases the cardioprotective effect of chronic continuous hypoxia in spontaneously hypertensive rats.
Clinical science. Roč. 131, č. 9 (2017), s. 865-881. ISSN 0143-5221. E-ISSN 1470-8736
R&D Projects: GA ČR(CZ) GA13-10267S; GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204
Institutional support: RVO:67985823
Keywords : chronic hypoxia * heart * hypertension * ischaemia–reperfusion injury * mitochondrial genome * mitochondrial permeability transition pore
OECD category: Physiology (including cytology)
Impact factor: 5.220, year: 2017 ; AIS: 1.431, rok: 2017
DOI: https://doi.org/10.1042/CS20170083
Permanent Link: http://hdl.handle.net/11104/0271673 - 5.0471806 - FGÚ 2017 RIV GB eng J - Journal Article
Vrbacký, Marek - Kovalčíková, Jana - Chawengsaksophak, Kallayanee - Beck, Inken - Mráček, Tomáš - Nůsková, Hana - Sedmera, David - Papoušek, František - Kolář, František - Sobol, Margaryta - Hozák, Pavel - Sedláček, Radislav - Houštěk, Josef
Knockout of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice.
Human Molecular Genetics. Roč. 25, č. 21 (2016), s. 4674-4685. ISSN 0964-6906. E-ISSN 1460-2083
R&D Projects: GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204; GA MŠMT(CZ) ED1.1.00/02.0109; GA TA ČR(CZ) TE01020118; GA MŠMT(CZ) LM2015062; GA MZd(CZ) NV16-33018A; GA MŠMT(CZ) LM2015040
Institutional support: RVO:67985823 ; RVO:68378050
Keywords : mouse knockout * mitochondria * ATP synthase * TMEM70 * biogenesis * mitochondrial diseases
OECD category: Human genetics
Impact factor: 5.340, year: 2016 ; AIS: 2.421, rok: 2016
DOI: https://doi.org/10.1093/hmg/ddw295
Permanent Link: http://hdl.handle.net/11104/0269138 - 6.0471751 - ÚMG 2017 RIV US eng J - Journal Article
Šedová, Lucie - Pravenec, Michal - Křenová, D. - Kazdová, L. - Zídek, Václav - Krupková, M. - Liška, F. - Křen, Vladimír - Šeda, Ondřej
Isolation of a Genomic Region Affecting Most Components of Metabolic Syndrome in a Chromosome-16 Congenic Rat Model.
PLoS ONE. Roč. 11, č. 3 (2016), č. článku e0152708. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA MŠMT(CZ) LL1204; GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR(CZ) GAP301/12/0696
Institutional support: RVO:67985823 ; RVO:68378050
Keywords : quantitative trait loci * blood-pressure * genetic-determinants * glucose-tolerance * hypertensive-rat * strains * reveals * identification * mechanisms * phenotypes
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.806, year: 2016 ; AIS: 1.053, rok: 2016
DOI: https://doi.org/10.1371/journal.pone.0152708
Permanent Link: http://hdl.handle.net/11104/0269084 - 7.0470496 - FGÚ 2017 RIV GB eng J - Journal Article
Hartmannová, H. - Piherová, L. - Tauchmannová, Kateřina - Kidd, K. - Acott, P. D. - Crocker, J. F. S. - Oussedik, Y. - Mallet, M. - Hodaňová, K. - Stránecký, V. - Přistoupilová, A. - Barešová, V. - Jedličková, I. - Živná, M. - Sovová, J. - Hůlková, H. - Robins, V. - Vrbacký, Marek - Pecina, Petr - Kaplanová, Vilma - Houštěk, Josef - Mráček, Tomáš - Thibeault, Y. - Bleyer, A. J. - Kmoch, S.
Acadian variant of Fanconi syndrome is caused by mitochondrial respiratory chain complex I deficiency due to a non-coding mutation in complex I assembly factor NDUFAF6.
Human Molecular Genetics. Roč. 25, č. 18 (2016), s. 4062-4079. ISSN 0964-6906. E-ISSN 1460-2083
R&D Projects: GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204
Institutional support: RVO:67985823
Keywords : Acadian variant of Fanconi syndrome * mitochondrial complex I deficiency * NDUFAF6 * C8ORF38 * non-coding mutation * alternative splicing variant * protein isoforms
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.340, year: 2016 ; AIS: 2.421, rok: 2016
DOI: https://doi.org/10.1093/hmg/ddw245
Permanent Link: http://hdl.handle.net/11104/0269081 - 8.0466616 - FGÚ 2017 RIV DE eng J - Journal Article
Kovářová, Nikola - Pecina, Petr - Nůsková, Hana - Vrbacký, Marek - Zeviani, M. - Mráček, Tomáš - Viscomi, C. - Houštěk, Josef
Data on cytochrome c oxidase assembly in mice and human fibroblasts or tissues induced by SURF1 defect.
Data in Brief. Roč. 7, June 01 (2016), s. 1004-1009. ISSN 2352-3409. E-ISSN 2352-3409
R&D Projects: GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204; GA MZd(CZ) NT12370
Institutional support: RVO:67985823
Keywords : cytochrome c oxidase * respiratory chain * SURF1 * knockout * doxycycline
OECD category: Human genetics
DOI: https://doi.org/10.1016/j.dib.2016.03.065
Permanent Link: http://hdl.handle.net/11104/0264887 - 9.0466612 - FGÚ 2017 RIV NL eng J - Journal Article
Kovářová, Nikola - Pecina, Petr - Nůsková, Hana - Vrbacký, Marek - Zeviani, M. - Mráček, Tomáš - Viscomi, C. - Houštěk, Josef
Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects.
Biochimica Et Biophysica Acta-Molecular Basis of Disease. Roč. 1862, č. 4 (2016), s. 705-715. ISSN 0925-4439. E-ISSN 1879-260X
R&D Projects: GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204; GA MZd(CZ) NT12370
Institutional support: RVO:67985823
Keywords : cytochrome c oxidase * respiratory supercomplexes * leigh syndrome * SURF1−/− mouse knockout * doxycycline * pulse-chase
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.476, year: 2016 ; AIS: 1.709, rok: 2016
DOI: https://doi.org/10.1016/j.bbadis.2016.01.007
Permanent Link: http://hdl.handle.net/11104/0264884 - 10.0461878 - FGÚ 2017 RIV NL eng J - Journal Article
Manakov, D. - Ujčíková, Hana - Pravenec, Michal - Novotný, J.
Alterations in the cardiac proteome of the spontaneously hypertensive rat induced by transgenic expression of CD36.
Journal of Proteomics. Roč. 145, Aug 11 (2016), s. 177-186. ISSN 1874-3919. E-ISSN 1876-7737
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204
Institutional support: RVO:67985823
Keywords : SHR * CD36 * heart * left and right ventricles * proteomics
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.914, year: 2016 ; AIS: 1.004, rok: 2016
DOI: https://doi.org/10.1016/j.jprot.2016.04.041
Permanent Link: http://hdl.handle.net/11104/0261441