Search results
- 1.0314717 - FGÚ 2009 CH eng A - Abstract
Smyčková, Helena - Jakubík, Jan - Randáková, Alena - Doležal, Vladimír
M2 muscarinic acetylcholine receptors precouple with GI/O but not with GQ/11 and GS/OLF G-proteins.
[M2 muskarinové acetylcholinové receptory vykazují precoupling pro G proteiny Gi/o, avšak nikoli pro Gq/11 a Gs/olf.]
6th FENS forum. Geneva: Swiss Society for Neuroscience, 2008. s. 124-124. ISBN 92-990014-3-X.
[FENS. Forum of European Neuroscience /6./. 12.07.2008-16.07.2008, Geneva]
R&D Projects: GA MŠMT(CZ) LC554; GA AV ČR(CZ) IAA500110703
Institutional research plan: CEZ:AV0Z50110509
Keywords : spo2 * cholinergic transmission * muscarinic receptors * G-proteins
Subject RIV: FH - Neurology
Permanent Link: http://hdl.handle.net/11104/0165133 - 2.0314711 - FGÚ 2009 IE eng A - Abstract
Jakubík, Jan - Smyčková, Helena - Doležal, Vladimír
Magnitude of negative cooperativity of allosteric interaction between GDP and agonist determines agonist afficacy at M2 muscarinic acetylcholine receptors.
[Velikost negativní kooperativity allosterické interakce mezi GDP a agonistou určuje velikost funkční účinnosti agonisty na M2 muskarinových receptorech pro acetylcholin.]
Keystone Symposia on Molecular and Cellular Biology. Killarney: INEC, 2008. s. 67-67.
[Keystone Symposia on Molecular and Cellular Biology. 18.05.2008-23.05.2008, Killarney]
R&D Projects: GA MŠMT(CZ) LC554; GA AV ČR(CZ) IAA500110703
Institutional research plan: CEZ:AV0Z50110509
Keywords : spo2 * muscarinic receptors * allosteric modulation * agonists efficacy
Subject RIV: EI - Biotechnology ; Bionics
Permanent Link: http://hdl.handle.net/11104/0165127 - 3.0091812 - FGÚ 2008 US eng A - Abstract
Smyčková, Helena - Jakubík, Jan - Doležal, Vladimír
Analysis of M2 muscarinic acetylcholine receptors coupling to Gi/o, Gs and Gq heterotrimeric GTP-binding proteins.
[Analýza spřažení M2 muskarinových receptorů pro acetylcholin s S Gi/o, Gs a Gq heterotrimerickými proteiny vážícími GTP.]
Journal of Neurochemistry. Wiley. Roč. 102, Suppl.1 (2007), s. 268-268. ISSN 0022-3042. E-ISSN 1471-4159.
[Biennial meeting of the International Society for Neurochemistry /21./ and Annual meeting of the American Society for Neurochemistry /38./. 19.08.2007-24.08.2007, Cancun]
R&D Projects: GA MŠMT(CZ) LC554; GA ČR(CZ) GA305/05/0452
Institutional research plan: CEZ:AV0Z50110509
Keywords : cpo1 * muscarinic receptors * agonist-specific conformations * allosteric interaction
Subject RIV: FH - Neurology
Permanent Link: http://hdl.handle.net/11104/0152318 - 4.0091778 - FGÚ 2008 CZ eng A - Abstract
Smyčková, Helena - Jakubík, Jan - Doležal, Vladimír
Analysis of coupling of M2 muscarinic acetylcholine receptors to Gi/o, Gs and Gq heterotrimeric GTP-binding proteins.
[Analýza spřažení muskarinových M2 receptorů s GTP-vázajícími proteiny tříd Gi/o, Gs a Gq.]
Physiological Research. Fyziologický ústav AV ČR, v. v. i. Roč. 56, č. 3 (2007), 32P-32P. ISSN 0862-8408. E-ISSN 1802-9973.
[Fyziologické dny /83./. 06.02.2007-08.02.2007, Brno]
R&D Projects: GA MŠMT(CZ) LC554; GA ČR(CZ) GA305/05/0452
Institutional research plan: CEZ:AV0Z50110509
Keywords : cpo1 * muscarinic * G-protein * agonist-specific
Subject RIV: ED - Physiology
Permanent Link: http://hdl.handle.net/11104/0152295