Search results
- 1.0584812 - BTÚ 2025 RIV US eng J - Journal Article
Sychra, T. - Spalenkova, A. - Balatka, S. - Václavíková, R. - Šeborová, K. - Ehrlichová, M. - Truksa, Jaroslav - Sandoval-Acuna, Cristian - Němcová, V. - Szabo, A. - Kočí, K. - Tesarova, T. - Chen, L. - Ojima, I. - Oliverius, M. - Souček, P.
Third-generation taxanes SB-T-121605 and SB-T-121606 are effective in pancreatic ductal adenocarcinoma.
iScience. Roč. 27, č. 2 (2024), č. článku 109044. E-ISSN 2589-0042
R&D Projects: GA ČR(CZ) GA21-14082S
Institutional support: RVO:86652036
Keywords : biological evaluation * cancer * microenvironment * cytotoxicity * transport * design
OECD category: Biochemistry and molecular biology
Impact factor: 5.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S2589004224002657?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0352753 - 2.0576613 - BTÚ 2024 RIV GB eng J - Journal Article
Bielcikova, Z. - Werner, Lukáš - Štursa, Jan - Černý, V. - Křížová, L. - Špaček, J. - Hlousek, S. - Vočka, M. - Bartosova, O. - Pesta, M. - Kološtová, K. - Klezl, P. - Bobek, V. - Truksa, Jaroslav - Štemberková-Hubáčková, Soňa - Petruzelka, L. - Michálek, P. - Neužil, Jiří
Mitochondrially targeted tamoxifen as anticancer therapy: case series of patients with renal cell carcinoma treated in a phase I/Ib clinical trial.
Therapeutic Advances in Medical Oncology. Roč. 15, March 28 (2023), č. článku 17588359231197957. ISSN 1758-8340. E-ISSN 1758-8359
R&D Projects: GA MZd(CZ) NU21-03-00545
Keywords : case series * efficacy * mechanism of action * mitocans * mitochondria
OECD category: Oncology
Impact factor: 4.9, year: 2022
Method of publishing: Open access
https://journals.sagepub.com/doi/10.1177/17588359231197957
Permanent Link: https://hdl.handle.net/11104/0347246 - 3.0565763 - BTÚ 2023 RIV CH eng J - Journal Article
Šeborová, K. - Koucká, K. - Spalenkova, A. - Holý, P. - Ehrlichová, M. - Sychra, T. - Chen, L. - Bendale, H. - Ojima, I. - Sandoval-Acuna, Cristian - Truksa, Jaroslav - Souček, P. - Václavíková, R.
Anticancer regimens containing third generation taxanes SB-T-121605 and SB-T-121606 are highly effective in resistant ovarian carcinoma model.
Frontiers in Pharmacology. Roč. 13, NOV 9 2022 (2022), č. článku 971905. ISSN 1663-9812. E-ISSN 1663-9812
R&D Projects: GA ČR(CZ) GA21-14082S
Institutional support: RVO:86652036
Keywords : ovarian carcinoma * resistance * paclitaxel * SB-T taxanes * efficacy * in vitro * in vivo
OECD category: Pharmacology and pharmacy
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fphar.2022.971905/full
Permanent Link: https://hdl.handle.net/11104/0337429 - 4.0565700 - BTÚ 2023 RIV DE eng J - Journal Article
Nováková, Zora - Miloševič, Mirko - Kutil, Zsofia - Ondráková, Markéta - Havlínová, Barbora - Kašpárek, Petr - Sandoval-Acuna, Cristian - Korandová, Zuzana - Truksa, Jaroslav - Vrbacký, Marek - Rohlena, Jakub - Bařinka, Cyril
Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene.
Scientific Reports. Roč. 12, č. 1 (2022), č. článku 17081. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MZd(CZ) NV17-32727A; GA ČR GA19-20553S; GA ČR(CZ) GA22-34507S; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
Institutional support: RVO:86652036 ; RVO:68378050 ; RVO:67985823
Keywords : DELTA-AMINOLEVULINATE SYNTHASE * VARIEGATE PORPHYRIA * MOLECULAR TARGET
OECD category: Cell biology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41598-022-21147-x
Permanent Link: https://hdl.handle.net/11104/0337228 - 5.0548987 - BTÚ 2022 RIV US eng J - Journal Article
Sandoval-Acuna, Cristian - Torrealba, Natalia - Tomkova, Veronika - Jadhav, Sukanya B. - Blažková, Kristýna - Merta, L. - Lettlová, Sandra - Adamcová, Miroslava Kari - Rosel, D. - Brabek, J. - Neužil, Jiří - Štursa, Jan - Werner, Lukáš - Truksa, Jaroslav
Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy.
Cancer Research. Roč. 81, č. 9 (2021), s. 2289-2303. ISSN 0008-5472. E-ISSN 1538-7445
R&D Projects: GA ČR(CZ) GA16-12816S; GA ČR(CZ) GA18-13103S; GA ČR(CZ) GC17-01192J; GA ČR(CZ) GA18-10832S
Institutional support: RVO:86652036 ; RVO:68378050
Keywords : sulfur cluster * cancer * biogenesis * breast * cells
OECD category: Oncology; Oncology (UMG-J)
Impact factor: 13.312, year: 2021
Method of publishing: Limited access
https://cancerres.aacrjournals.org/content/81/9/2289
Permanent Link: http://hdl.handle.net/11104/0325023 - 6.0542251 - BTÚ 2022 RIV CH eng J - Journal Article
Krijt, J. - Frýdlová, J. - Gurieva, I. - Přikryl, P. - Báječný, M. - Steinbicker, A. U. - Vokurka, M. - Truksa, Jaroslav
Matriptase-2 and Hemojuvelin in Hepcidin Regulation: In Vivo Immunoblot Studies in Mask Mice.
International Journal of Molecular Sciences. Roč. 22, č. 5 (2021), č. článku 2650. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA18-13103S; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : hepcidin * transferrin receptor * neogenin * Hjv
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/5/2650
Permanent Link: http://hdl.handle.net/11104/0319715 - 7.0536341 - BTÚ 2021 RIV CH eng J - Journal Article
Fuentes-Retamal, S. - Sandoval-Acuna, Cristian - Peredo-Silva, L. - Guzman-Rivera, D. - Pavani, M. - Torrealba, Natalia - Truksa, Jaroslav - Castro-Castillo, V. - Catalan, M. - Kemmerling, U. - Urra, F. A. - Ferreira, J.
Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells.
Cells. Roč. 9, č. 2 (2020), č. článku 407. E-ISSN 2073-4409
Institutional support: RVO:86652036
Keywords : inhibition of the electron transport chain * inhibition of alpha-ketoglutarate dehydrogenase complex * mitochondrially targeted
OECD category: Cell biology
Impact factor: 6.600, year: 2020
Method of publishing: Open access
https://www.mdpi.com/2073-4409/9/2/407
Permanent Link: http://hdl.handle.net/11104/0314143 - 8.0522123 - BTÚ 2020 RIV US eng J - Journal Article
Vondrusová, Magdaléna - Bezawork-Geleta, A. - Sachaphibulkij, K. - Truksa, Jaroslav - Neužil, Jiří
The effect of mitochondrially targeted anticancer agents on mitochondrial (super)complexes.
Methods in molecular biology. Roč. 1265, č. 2015 (2015), s. 195-208. ISSN 1940-6029
Institutional support: RVO:86652036
Keywords : antineoplastic agent * mitochondrial protein * multienzyme complex
OECD category: Biochemistry and molecular biology
Method of publishing: Limited access
https://link.springer.com/protocol/10.1007%2F978-1-4939-2288-8_15
Permanent Link: http://hdl.handle.net/11104/0306632 - 9.0520661 - BTÚ 2020 RIV US eng J - Journal Article
Frýdlová, J. - Rogalsky, D.W. - Truksa, Jaroslav - Nečas, E. - Vokurka, M. - Krijt, J.
Effect of stimulated erythropoiesis on liver SMAD signaling pathway in iron-overloaded and iron-deficient mice.
PLoS ONE. Roč. 14, č. 4 (2019), č. článku e0215028. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR(CZ) GA18-13103S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : transferrin receptor 2 * identification * anemia
OECD category: Biochemistry and molecular biology
Impact factor: 2.740, year: 2019
Method of publishing: Open access
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215028
Permanent Link: http://hdl.handle.net/11104/0305360 - 10.0520490 - BTÚ 2020 RIV US eng J - Journal Article
Tomkova, Veronika - Sandoval-Acuna, Cristian - Torrealba, Natalia - Truksa, Jaroslav
Mitochondrial fragmentation, elevated mitochondrial superoxide and respiratory supercomplexes disassembly is connected with the tamoxifen-resistant phenotype of breast cancer cells.
Free Radical Biology and Medicine. Roč. 143, NOV 1 2019 (2019), s. 510-521. ISSN 0891-5849. E-ISSN 1873-4596
R&D Projects: GA ČR(CZ) GA16-12816S; GA ČR(CZ) GA18-13103S; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LQ1604
Institutional support: RVO:86652036
Keywords : activated protein-kinase * estrogen-receptor-alpha * acquired-resistance * Mitochondrial fragmentation * Reactive oxygen species
OECD category: Biochemistry and molecular biology
Impact factor: 6.170, year: 2019
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0891584919310044?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0305193