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  1. 1.
    0585346 - FGÚ 2025 RIV GB eng J - Journal Article
    Němečková, I. - Eissazadeh, S. - Rathouská Urbánková, J. - Šilhavý, Jan - Malínská, H. - Pravenec, Michal - Nachtigal, P.
    Transgenic human C-reactive protein affects oxidative stress but not inflammation biomarkers in the aorta of spontaneously hypertensive rats.
    BMC Cardiovascular Disorders. Roč. 24, č. 1 (2024), č. článku 211. ISSN 1471-2261. E-ISSN 1471-2261
    R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) LUAUS23095
    Institutional support: RVO:67985823
    Keywords : C-reactive protein * spontaneously hypertensive rat * aorta * endothelial dysfunction * oxidative stress
    OECD category: Cardiac and Cardiovascular systems
    Impact factor: 2.1, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1186/s12872-024-03870-7
    Permanent Link: https://hdl.handle.net/11104/0353066
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    24_0041_0585346.pdf01.7 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0583232 - FGÚ 2025 RIV US eng J - Journal Article
    Šilhavý, Jan - Mlejnek, Petr - Šimáková, Miroslava - Liška, František - Malínská, H. - Marková, I. - Hüttl, M. - Miklánková, D. - Mušálková, D. - Stránecký, V. - Kmoch, S. - Sticová, E. - Vrbacký, Marek - Mráček, Tomáš - Pravenec, Michal
    Spontaneous nonsense mutation in the tuftelin 1 gene is associated with abnormal hair appearance and amelioration of glucose and lipid metabolism in the rat.
    Physiological Genomics. Roč. 56, č. 1 (2024), s. 65-73. ISSN 1094-8341. E-ISSN 1531-2267
    R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) LUAUS23095; GA ČR(CZ) GA21-18993S
    Research Infrastructure: NCMG III - 90267
    Institutional support: RVO:67985823
    Keywords : hepatic proteome * lipid and glucose metabolism * rat * spontaneous nonsense mutation * tuftelin 1 gene * Tuft1
    OECD category: Cardiac and Cardiovascular systems
    Impact factor: 4.6, year: 2022
    https://doi.org/10.1152/physiolgenomics.00084.2023
    Permanent Link: https://hdl.handle.net/11104/0351234
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    24_0012_0583232.pdf32 MBPublisher’s postprintopen-access
     
     
  3. 3.
    0571373 - FGÚ 2024 RIV US eng J - Journal Article
    Šilhavý, Jan - Mlejnek, Petr - Šimáková, Miroslava - Marková, I. - Malínská, H. - Hüttl, M. - Kazdová, L. - Kazantsev, D. - Mancini, M. - Novotný, J. - Pravenec, Michal
    CD36 regulates substrates utilisation in brown adipose tissue of spontaneously hypertensive rats: In vitro study.
    PLoS ONE. Roč. 18, č. 4 (2023), č. článku e0283276. ISSN 1932-6203. E-ISSN 1932-6203
    R&D Projects: GA MŠMT(CZ) LX22NPO5104
    Institutional support: RVO:67985823
    Keywords : brown adipose tissue * phosphorylation * spontaneously hypertensive rat
    OECD category: Physiology (including cytology)
    Impact factor: 3.7, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1371/journal.pone.0283276
    Permanent Link: https://hdl.handle.net/11104/0342614
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    23_0034_0571373.pdf01.5 MBPublisher’s postprintopen-access
     
     
  4. 4.
    0571371 - FGÚ 2024 RIV CH eng J - Journal Article
    Hüttl, M. - Marková, I. - Miklánková, D. - Zapletalová, I. - Kujal, P. - Šilhavý, Jan - Pravenec, Michal - Malínská, H.
    Hypolipidemic and insulin sensitizing effects of salsalate beyond suppressing inflammation in a prediabetic rat model.
    Frontiers in Pharmacology. Roč. 14, 3 Apr (2023), č. článku 1117683. ISSN 1663-9812. E-ISSN 1663-9812
    R&D Projects: GA MŠMT(CZ) LX22NPO5104
    Institutional support: RVO:67985823
    Keywords : salsalate * low-grade inflammation * prediabetes * lipid metabolism * cytochrome P450 * oxidative stress
    OECD category: Endocrinology and metabolism (including diabetes, hormones)
    Impact factor: 5.6, year: 2022
    Method of publishing: Open access
    https://doi.org/10.3389/fphar.2023.1117683
    Permanent Link: https://hdl.handle.net/11104/0342610
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    23_0031_0571371.pdf01.9 MBPublisher’s postprintopen-access
     
     
  5. 5.
    0570442 - FGÚ 2024 RIV CH eng J - Journal Article
    Šilhavý, Jan - Mlejnek, Petr - Šimáková, Miroslava - Malínská, H. - Marková, I. - Hüttl, M. - Miklánková, D. - Kazdová, L. - Vrbacký, Marek - Pecinová, Alena - Mráček, Tomáš - Pravenec, Michal
    Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome.
    Metabolites. Roč. 13, č. 2 (2023), č. článku 192. E-ISSN 2218-1989
    R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA ČR(CZ) GA21-18993S
    Institutional support: RVO:67985823
    Keywords : spontaneously hypertensive rat * hereditary hypertriglyceridemic rat * beetroot * lipids * proteomics * glycerophospholipid metabolism * mTOR signalling
    OECD category: Endocrinology and metabolism (including diabetes, hormones)
    Impact factor: 4.1, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/2218-1989/13/2/192
    Permanent Link: https://hdl.handle.net/11104/0341737
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    23_0017_0570442.pdf01.7 MBPublisher’s postprintopen-access
     
     
  6. 6.
    0560439 - FGÚ 2023 RIV CH eng J - Journal Article
    Malínská, H. - Hüttl, M. - Marková, I. - Miklánková, D. - Hojná, Silvie - Papoušek, František - Šilhavý, Jan - Mlejnek, Petr - Zicha, Josef - Hrdlička, Jaroslav - Pravenec, Michal - Vaněčková, Ivana
    Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein.
    Biomedicines. Roč. 10, č. 9 (2022), č. článku 2066. E-ISSN 2227-9059
    R&D Projects: GA ČR(CZ) GA19-06199S; GA MŠMT(CZ) LX22NPO5104
    Institutional support: RVO:67985823
    Keywords : SHR-CRP * SGLT-2 inhibitor * gene expression * age * lipid metabolism
    OECD category: Physiology (including cytology)
    Impact factor: 4.7, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/2227-9059/10/9/2066
    Permanent Link: https://hdl.handle.net/11104/0333368
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    22_0073_0560439.pdf01.9 MBPublisher’s postprintopen-access
     
     
  7. 7.
    0557065 - FGÚ 2023 RIV US eng J - Journal Article
    Senko, A. N. - Overall, R. W. - Šilhavý, Jan - Mlejnek, Petr - Malínská, H. - Hüttl, M. - Marková, I. - Fabel, K. S. - Lu, L. - Stuchlík, Aleš - Williams, R. W. - Pravenec, Michal - Kempermann, G.
    Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose.
    PLoS Genetics. Roč. 18, č. 4 (2022), č. článku e1009638. ISSN 1553-7404. E-ISSN 1553-7404
    R&D Projects: GA ČR(CZ) GA20-00939S
    Grant - others:AV ČR(CZ) AP1502
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:67985823
    Keywords : spontaneously hypertensive-rats * triple t complex * ataxia-telangiectasia * sphingosine 1-phosphate * mammalian target * candidate genes * nervous-system * cell-survival * igf-i * expression
    OECD category: Genetics and heredity (medical genetics to be 3)
    Impact factor: 4.5, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1371/journal.pgen.1009638
    Permanent Link: http://hdl.handle.net/11104/0331169
     
     
  8. 8.
    0556808 - FGÚ 2023 RIV CH eng J - Journal Article
    Lusk, R. - Hoffman, P.L. - Mahaffey, S. - Rosean, S. - Smith, H. - Šilhavý, Jan - Pravenec, Michal - Tabakoff, B. - Saba, L. M.
    Beyond Genes: Inclusion of Alternative Splicing and Alternative Polyadenylation to Assess the Genetic Architecture of Predisposition to Voluntary Alcohol Consumption in Brain of the HXB/BXH Recombinant Inbred Rat Panel.
    Frontiers in genetics. Roč. 13, Mar 15 (2022), č. článku 821026. E-ISSN 1664-8021
    R&D Projects: GA ČR(CZ) GA13-04420S
    Grant - others:AV ČR(CZ) AP1502
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:67985823
    Keywords : voluntary alcohol consumption * alternative splicing * alternative polyadenylation * HXB/BXH recombinant inbred strains
    OECD category: Genetics and heredity (medical genetics to be 3)
    Impact factor: 3.7, year: 2022
    Method of publishing: Open access
    https://doi.org/10.3389/fgene.2022.821026
    Permanent Link: http://hdl.handle.net/11104/0331116
     
     
  9. 9.
    0555857 - FGÚ 2023 RIV CH eng J - Journal Article
    Marković, Aleksandra - Tauchmannová, Kateřina - Šimáková, Miroslava - Mlejnek, Petr - Kaplanová, Vilma - Pecina, Petr - Pecinová, Alena - Papoušek, František - Liška, František - Šilhavý, Jan - Mikešová, Jana - Neckář, Jan - Houštěk, Josef - Pravenec, Michal - Mráček, Tomáš
    Genetic Complementation of ATP Synthase Deficiency Due to Dysfunction of TMEM70 Assembly Factor in Rat.
    Biomedicines. Roč. 10, č. 2 (2022), č. článku 276. E-ISSN 2227-9059
    R&D Projects: GA ČR(CZ) GA20-25768S; GA MZd(CZ) NU21-07-00550
    Grant - others:AV ČR(CZ) AP1502
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:67985823
    Keywords : mitochondria disease * ATP synthase deficiency * TMEM70 factor * transgenic rescue * gene therapy
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.7, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/2227-9059/10/2/276
    Permanent Link: http://hdl.handle.net/11104/0330319
     
     
  10. 10.
    0555849 - FGÚ 2023 RIV CH eng J - Journal Article
    Šilhavý, Jan - Mlejnek, Petr - Šimáková, Miroslava - Liška, František - Kubovčiak, Jan - Sticová, E. - Pravenec, Michal
    Sodium Accumulation and Blood Capillary Rarefaction in the Skin Predispose Spontaneously Hypertensive Rats to Salt Sensitive Hypertension.
    Biomedicines. Roč. 10, č. 2 (2022), č. článku 376. E-ISSN 2227-9059
    Grant - others:AV ČR(CZ) AP1502
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:67985823 ; RVO:68378050
    Keywords : salt-sensitive hypertension * spontaneously hypertensive rat * skin * sodium * salt * blood pressure * capillary rarefaction * gene expression
    OECD category: Physiology (including cytology)
    Impact factor: 4.7, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/2227-9059/10/2/376
    Permanent Link: http://hdl.handle.net/11104/0330309
     
     

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