Search results

  1. 1.
    0583751 - ÚOCHB 2024 CZ eng A - Abstract
    Štěpánová, Sille - Gutten, Ondrej - Buděšínský, Miloš - Břehová, Petra - Rulíšek, Lubomír - Kašička, Václav
    Acidity constants of cyclic diadenosine diphosphorothioate and its difluorinated derivatives determined by capillary electrophoresis.
    9. ročník konference Česká chromatografická škola – HPLC.cz 2023. Program konference/Program sekce plakátových sdělení. Praha: Česká chromatografická škola, 2023. s. 20.
    [Česká chromatografická škola – HPLC.cz 2023 /9./. 14.05.2023-17.05.2023, Zaječí]
    Institutional support: RVO:61388963
    Keywords : acidity constant * capillary electrophoresis * cyclic dinucleotides diphosphorothioates
    OECD category: Analytical chemistry
    http://ceskachromatografickaskola.cz/admin/Include/Data/getfile.php?id_soubor=64&db=2-ceskachro
    Permanent Link: https://hdl.handle.net/11104/0351740
    FileDownloadSizeCommentaryVersionAccess
    Česká chromatografická škola – HPLC.cz 2023. Program sekce plakátových sdělení.pdf02.2 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0578953 - ÚOCHB 2024 RIV CZ eng A - Abstract
    Dejmek, Milan - Štefek, Milan - Otava, Tomáš - Misehe, Mbilo - Krafčíková, Petra - Klíma, Martin - Šála, Michal - Břehová, Petra - Bouřa, Evžen - Nencka, Radim
    Novel antiviral strategies targeting methyltransferases, RIPK2, and STING pathway.
    Czech Chemical Society Symposium Series. Roč. 21, č. 5 (2023), s. 182. ISSN 2336-7202.
    [Annual meeting of the National Institute of Virology and Bacteriology (NIVB) /2./. 02.10.2023-05.10.2023, Kutná Hora]
    R&D Projects: GA MŠMT(CZ) LX22NPO5103
    Institutional support: RVO:61388963
    Keywords : methylstransferases * RIPK2 inhibitors * STING
    OECD category: Virology
    http://www.ccsss.cz/index.php/ccsss/issue/view/41/75
    Permanent Link: https://hdl.handle.net/11104/0347856
    FileDownloadSizeCommentaryVersionAccess
    NIVB Meeting 2023_L04.pdf2396 KBPublisher’s postprintopen-access
     
     
  3. 3.
    0552669 - ÚOCHB 2022 CZ eng A - Abstract
    Pimková Polidarová, Markéta - Brázdová, Andrea - Vaneková, Lenka - Břehová, Petra - Birkuš, Gabriel
    The antiviral potential of synthetic sting agonists and their prodrugs against chronic hepatitis B.
    Czech Chemical Society Symposium Series. Roč. 19, č. 1 (2021), s. 31. ISSN 2336-7202.
    [Interdisciplinary Meeting of Young Researchers and Students in the Field of Chemistry, Biochemistry, Molecular Biology, and Biomaterials /20./. 17.05.2021-20.05.2021, Milovy, On-line Meeting]
    R&D Projects: GA MŠMT(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : chronic hepatitis B * STING
    OECD category: Virology
    Permanent Link: http://hdl.handle.net/11104/0327787
     
     
  4. 4.
    0518499 - ÚOCHB 2020 TH eng A - Abstract
    Břehová, Petra - Šmídková, Markéta - Skácel, Jan - Dračínský, Martin - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, W. J. - Janeba, Zlatko
    Synthesis of acyclic nucleoside phosphonates derived from 2-aminothiazoles and their evaluation as inhibitors of bacterial and human adenylate cyclases.
    20th Tetrahedron Symposium. Bangkok: Elsevier, 2019. P1.005, „P1004“.
    [Tetrahedron Symposium /20./. 18.06.2019-21.06.2019, Bangkok]
    Institutional support: RVO:61388963
    Keywords : nucleoside analogues * adenylate cyclases * aminothiazoles
    OECD category: Organic chemistry
    Permanent Link: http://hdl.handle.net/11104/0303890
     
     
  5. 5.
    0481189 - ÚOCHB 2018 CZ eng A - Abstract
    Břehová, Petra - Šmídková, Markéta - Skácel, Jan - Dračínský, Martin - Mertlíková-Kaiserová, Helena - Velasquez, M. P. S. - Watts, V. J. - Janeba, Zlatko
    Synthesis of acyclic nucleoside phosphonates with unnatural heterocyclic bases bearing aryl substituents and their inhibitory activity towards bacterial and human adenylate cyclases.
    SCNAC 2017. 17th Symposium on Chemistry of Nucleic Acid Components. Praha: Confis Conference, 2017. s. 125.
    [SCNAC 2017. Symposium on Chemistry of Nucleic Acid Components /17./. 04.06.2017-09.06.2017, Český Krumlov]
    R&D Projects: GA MV VG20102015046
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonates (ANPs) * adenylate cyclase toxin (ACT) * Bordetella pertussis
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0276789
     
     
  6. 6.
    0464963 - ÚOCHB 2017 ES eng A - Abstract
    Břehová, Petra - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Skácel, Jan - Dračínský, Martin - Janeba, Zlatko
    Synthesis of acyclic nucleoside phosphonates bearing aryl substituent at the acyclic linker as potential inhibitors of adenylate cyclase toxin from Bordetella pertussis.
    17th Tetrahedron Symposium. Challenges in Biological, Bioorganic, Organic and Medicinal Chemistry. Sitges: Elsevier, 2016.
    [Tetrahedron Symposium. Challenges in Biological, Bioorganic, Organic and Medicinal Chemistry /17./. 28.06.2016-01.07.2016, Sitges]
    R&D Projects: GA MV VG20102015046
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonates (ANPs) * adenylate cyclase toxin (ACT) * Bordetella pertussis
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0263697
     
     
  7. 7.
    0454279 - ÚOCHB 2016 CZ eng A - Abstract
    Břehová, Petra - Šmídková, Markéta - Mertlíková-Kaiserová, Helena - Dračínský, Martin - Janeba, Zlatko
    Synthesis of acyclic nucleoside phosphonates bearing (N-methyl)anthraniloyl substituent as potential inhibitors of adenylate cyclase toxin from Bordetella Pertussis.
    Liblice 2015. 50th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2015. s. 61.
    [Liblice 2015. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /50./. 06.11.2015-08.11.2015, Olomouc]
    R&D Projects: GA MV VG20102015046
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonates * adenylate cyclase toxin * prodrugs
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0256230
     
     
  8. 8.
    0351701 - ÚOCHB 2011 NL eng A - Abstract
    Janeba, Zlatko - Břehová, Petra - Česnek, Michal - Dračínský, Martin - Holý, Antonín
    Efficient synthesis and antiviral properties of base substituted 2,4-diamino-6-(R)-[3-hydroxy-2-(phosphonomethoxy)propoxy]pyrimidine (HPMPO-DAPym).
    Antivirals Congress. Celebrating 30 years of the journal Antiviral Research. Amsterdam: Elsevier, 2010. P1.16-P1.16.
    [Antivirals Congress. Celebrating 30 years of the journal Antiviral Research. 07.11.2010-09.11.2010, Amsterdam]
    R&D Projects: GA MŠMT 1M0508
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : HPMPO-DAPym * ANPs * acyclic nucleoside phosphonates * SAR * cross-couplings
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0191396
     
     
  9. 9.
    0346737 - ÚOCHB 2011 NL eng A - Abstract
    Břehová, Petra - Dračínský, Martin - Holý, Antonín
    Efficient Synthesis and Biological Properties of Base Substituted 2,4-Diamino-6-(R)-[3-hydroxy-2-(phosphonomethoxy)propoxy]pyrimidine (HPMPO-DAPy).
    Antiviral Research. Elsevier. Roč. 86, č. 1 (2010), A52-A52. ISSN 0166-3542. E-ISSN 1872-9096.
    [International Conference on Antiviral Research (ICAR) /23./. 12.04.2010-28.04.2010, San Francisco]
    R&D Projects: GA MŠMT 1M0508; GA AV ČR 1QS400550501
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : antivirals * HPMPO-DAPy * acyclic nucleoside phosphonates
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0187678
     
     


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