Search results
- 1.0531418 - ÚOCHB 2021 RIV CH eng J - Journal Article
Boušová, Kristýna - Barvík, I. - Herman, P. - Hofbauerová, Kateřina - Monincová, Lenka - Majer, Pavel - Zouharová, Monika - Vetýšková, Veronika - Poštulková, Klára - Vondrášek, Jiří
Mapping of CaM, S100A1 and PIP2-Binding Epitopes in the Intracellular N- and C-Termini of TRPM4.
International Journal of Molecular Sciences. Roč. 21, č. 12 (2020), č. článku 4323. E-ISSN 1422-0067
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : TRPM4 channel * binding epitope * PIP2 * CaM * S100A1 * fluorescence anisotropy * docking * molecular dynamics simulations
OECD category: Biochemistry and molecular biology; Microbiology (MBU-M)
Impact factor: 5.924, year: 2020
Method of publishing: Open access
https://doi.org/10.3390/ijms21124323
Permanent Link: http://hdl.handle.net/11104/0310083 - 2.0498559 - ÚOCHB 2019 RIV CH eng J - Journal Article
Adla, Santosh Kumar - Slavíková, Barbora - Chodounská, Hana - Vyklický, Vojtěch - Ladislav, Marek - Hubálková, Pavla - Krausová, Barbora - Smejkalová, Tereza - Nekardová, Michaela - Šmídková, Markéta - Monincová, Lenka - Souček, Radko - Vyklický ml., Ladislav - Kudová, Eva
Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif.
Frontiers in Pharmacology. Roč. 9, Nov 12 (2018), č. článku 1299. ISSN 1663-9812. E-ISSN 1663-9812
R&D Projects: GA TA ČR(CZ) TE01020028; GA ČR(CZ) GBP208/12/G016; GA ČR(CZ) GA17-02300S; GA ČR(CZ) GJ16-03913Y; GA MZd(CZ) NV15-29370A; GA MŠMT LO1302; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:AV ČR(CZ) MSM200111601
Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : neurosteroid * amide * NMDA receptor * plasma stability * structure-activity relationship
OECD category: Biochemistry and molecular biology
Impact factor: 3.845, year: 2018
https://www.frontiersin.org/articles/10.3389/fphar.2018.01299/full
Permanent Link: http://hdl.handle.net/11104/0291127 - 3.0490659 - ÚOCHB 2019 RIV US eng J - Journal Article
Zimmermann, S. C. - Tichý, Tomáš - Vávra, Jan - Dash, R. P. - Slusher, C. E. - Gadiano, A. J. - Wu, Y. - Jančařík, Andrej - Tenora, Lukáš - Monincová, Lenka - Prchalová, E. - Riggins, G. J. - Majer, Pavel - Slusher, B. S. - Rais, R.
N-Substituted Prodrugs of Mebendazole Provide Improved Aqueous Solubility and Oral Bioavailability in Mice and Dogs.
Journal of Medicinal Chemistry. Roč. 61, č. 9 (2018), s. 3918-3929. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:61388963
Keywords : anthelmintic drug mebendazole * water soluble prodrugs * in vivo
OECD category: Organic chemistry
Impact factor: 6.054, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284815 - 4.0489614 - ÚOCHB 2019 RIV GB eng J - Journal Article
Boušová, Kristýna - Heřman, P. - Večeř, J. - Bednárová, Lucie - Monincová, Lenka - Majer, Pavel - Vyklický, L. - Vondrášek, Jiří - Teisinger, J.
Shared CaM- and S100A1-binding epitopes in the distal TRPM4 N terminus.
FEBS Journal. Roč. 285, č. 3 (2018), s. 599-613. ISSN 1742-464X. E-ISSN 1742-4658
Institutional support: RVO:61388963
Keywords : calmodulin * fluorescence anisotropy * ligand-binding domains * S100A1 * TRPM4 channel
OECD category: Biochemistry and molecular biology
Impact factor: 4.739, year: 2018
Permanent Link: http://hdl.handle.net/11104/0283997 - 5.0482244 - ÚOCHB 2018 RIV GB eng J - Journal Article
Nešuta, Ondřej - Buděšínský, Miloš - Hadravová, Romana - Monincová, Lenka - Humpolíčková, Jana - Čeřovský, Václav
How proteases from Enterococcus faecalis contribute to its resistance to short alpha-helical antimicrobial peptides.
Pathogens and Disease. Roč. 75, č. 7 (2017), č. článku ftx091. ISSN 2049-632X. E-ISSN 2049-632X
R&D Projects: GA TA ČR(CZ) TA04010638; GA MZd(CZ) NV16-27726A
Institutional support: RVO:61388963
Keywords : antimicrobial peptides * biofilm * C-terminal deamidation * gelatinase * protease
OECD category: Microbiology
Impact factor: 2.337, year: 2017
Permanent Link: http://hdl.handle.net/11104/0277623 - 6.0480326 - ÚOCHB 2018 RIV US eng J - Journal Article
Rais, R. - Vávra, Jan - Tichý, Tomáš - Dash, R. P. - Gadiano, A. J. - Tenora, Lukáš - Monincová, Lenka - Bařinka, Cyril - Alt, J. - Zimmermann, S. C. - Slusher, C. E. - Wu, Y. - Wozniak, K. - Majer, Pavel - Tsukamoto, T. - Slusher, B. S.
Discovery of a para-Acetoxy-benzyl Ester Prodrug of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor as Oral Therapy for Neuropathic Pain.
Journal of Medicinal Chemistry. Roč. 60, č. 18 (2017), s. 7799-7809. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LM2015043; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : linked acidic dipeptidase * peripheral mononeuropathy * biological activity
OECD category: Organic chemistry; Organic chemistry (BTO-N)
Impact factor: 6.253, year: 2017
Permanent Link: http://hdl.handle.net/11104/0276130 - 7.0478419 - ÚOCHB 2018 RIV DE eng J - Journal Article
Tůmová, Tereza - Monincová, Lenka - Nešuta, Ondřej - Čeřovský, Václav - Kašička, Václav
Determination of effective charges and ionic mobilities of polycationic antimicrobial peptides by capillary isotachophoresis and capillary zone electrophoresis.
Electrophoresis. Roč. 38, č. 16 (2017), s. 2018-2024. ISSN 0173-0835. E-ISSN 1522-2683
R&D Projects: GA ČR(CZ) GA15-01948S
Institutional support: RVO:61388963
Keywords : antimicrobial peptides * capillary isotachophoresis * counterion condensation * effective charge * ionic mobility
OECD category: Analytical chemistry
Impact factor: 2.569, year: 2017
Permanent Link: http://hdl.handle.net/11104/0274538 - 8.0470552 - ÚOCHB 2017 RIV DE eng J - Journal Article
Tůmová, Tereza - Monincová, Lenka - Čeřovský, Václav - Kašička, Václav
Estimation of acidity constants, ionic mobilities and charges of antimicrobial peptides by capillary electrophoresis.
Electrophoresis. Roč. 37, 23/24 (2016), s. 3186-3195. ISSN 0173-0835. E-ISSN 1522-2683
R&D Projects: GA ČR(CZ) GA15-01948S
Institutional support: RVO:61388963
Keywords : acid dissociation constant * antimicrobial peptides * capillary electrophoresis * charge * mobility * Pka
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 2.744, year: 2016
Permanent Link: http://hdl.handle.net/11104/0268156 - 9.0464672 - ÚOCHB 2017 RIV US eng J - Journal Article
Rais, R. - Jančařík, Andrej - Tenora, Lukáš - Nedelcovych, M. - Alt, J. - Englert, J. - Rojas, C. - Le, A. - Elgogary, A. - Tan, J. - Monincová, Lenka - Pate, K. - Adams, R. - Ferraris, D. - Powell, J. - Majer, Pavel - Slusher, B. S.
Discovery of 6-Diazo-5-oxo-L-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma.
Journal of Medicinal Chemistry. Roč. 59, č. 18 (2016), s. 8621-8633. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:61388963
Keywords : phase I * glutamine metabolism * adjuvant temozolomide
Subject RIV: CC - Organic Chemistry
Impact factor: 6.259, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263477 - 10.0463996 - ÚOCHB 2017 RIV GB eng J - Journal Article
Jirků, M. - Lánský, Z. - Bednárová, Lucie - Šulc, M. - Monincová, Lenka - Majer, Pavel - Vyklický, L. - Vondrášek, Jiří - Teisinger, J. - Boušová, Kristýna
The characterization of a novel S100A1 binding site in the N-terminus of TRPM1.
International Journal of Biochemistry and Cell Biology. Roč. 78, Sep (2016), s. 186-193. ISSN 1357-2725. E-ISSN 1878-5875
Institutional support: RVO:61388963
Keywords : TRPM1 channel * binding site * calcium-binding protein S100A1 * steady-state fluorescence anisotropy * molecular modeling * circular dichroism
Subject RIV: CE - Biochemistry
Impact factor: 3.505, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263083