Search results
- 1.0392089 - BTÚ 2014 RIV GB eng J - Journal Article
Moreno-Sanchez, R. - Hernandez-Esquivel, L. - Rivero-Segura, N.A. - Marin-Hernandez, A. - Neužil, Jiří - Ralph, S. J. - Rodriguez-Enriquez, S.
Reactive oxygen species are generated by the respiratory complex II - evidence for lack of contribution of the reverse electron flow in complex I.
FEBS Journal. Roč. 280, č. 3 (2013), s. 927-938. ISSN 1742-464X. E-ISSN 1742-4658
Institutional research plan: CEZ:AV0Z50520701
Keywords : anti-cancer drugs * mitochondria * respiratory complex II
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.986, year: 2013 ; AIS: 1.243, rok: 2013
DOI: https://doi.org/10.1111/febs.12086
Permanent Link: http://hdl.handle.net/11104/0221063 - 2.0383182 - BTÚ 2013 RIV NL eng J - Journal Article
Rodriguez-Enriquez, S. - Hernandez-Esquivel, L. - Marin-Hernandez, A. - Dong, L.-F. - Akporiaye, E. - Neužil, Jiří - Ralph, S.J. - Moreno-Sanchez, R.
Molecular mechanism for the selective impairment of cancer mitochondrial function by a mitochondrially targeted vitamin E analogue.
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1817, č. 9 (2012), s. 1597-1607. ISSN 0005-2728. E-ISSN 1879-2650
R&D Projects: GA ČR GAP301/10/1937
Institutional research plan: CEZ:AV0Z50520701
Keywords : Mitochondria * respiratory complex II * vitamin E analogs
Subject RIV: CE - Biochemistry
Impact factor: 4.624, year: 2012 ; AIS: 1.521, rok: 2012
DOI: https://doi.org/10.1016/j.bbabio.2012.05.005
Permanent Link: http://hdl.handle.net/11104/0213201 - 3.0369494 - BTÚ 2012 RIV US eng J - Journal Article
Ralph, S.J. - Moreno-Sanchez, R. - Neužil, Jiří - Rodriguez-Enriquez, S.
Inhibitors of Succinate: Quinone Reductase/Complex II Regulate Production of Mitochondrial Reactive Oxygen Species and Protect Normal Cells from Ischemic Damage but Induce Specific Cancer Cell Death.
Pharmaceutical Research. Roč. 28, č. 11 (2011), s. 2695-2730. ISSN 0724-8741. E-ISSN 1573-904X
Institutional research plan: CEZ:AV0Z50520701
Keywords : Mitocans * SDH/Complex II * mitochondrial ROS production
Subject RIV: CE - Biochemistry
Impact factor: 4.093, year: 2011 ; AIS: 1.197, rok: 2011
DOI: https://doi.org/10.1007/s11095-011-0566-7
Permanent Link: http://hdl.handle.net/11104/0006745 - 4.0361293 - BTÚ 2013 RIV US eng J - Journal Article
Dong, L.F. - Jameson, V.J.A. - Tilly, D. - Černý, Jiří - Mahdavian, E. - Marin-Hernandez, A. - Hernandez-Esquivel, L. - Rodriguez-Enriquez, S. - Štursa, Jan - Witting, P.K. - Stantic, B. - Rohlena, Jakub - Truksa, Jaroslav - Klučková, Katarína - Dyason, J.C. - Ledvina, Miroslav - Salvatore, B.A. - Moreno-Sanchez, R. - Coster, M. - Ralph, S.J. - Smith, A.J. - Neužil, Jiří
Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex.
Journal of Biological Chemistry. Roč. 286, č. 5 (2011), s. 3717-3728. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA204/08/0811; GA ČR(CZ) GAP301/10/1937; GA AV ČR(CZ) IAA500520702; GA AV ČR(CZ) KAN200520703; GA AV ČR(CZ) KJB500970904
Institutional research plan: CEZ:AV0Z50520701; CEZ:AV0Z4055905
Keywords : Apoptosis induction * proximal ubiquinone-binding site of mitochondrial complex II * reactive oxygen species
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.773, year: 2011 ; AIS: 2.031, rok: 2011
DOI: https://doi.org/10.1074/jbc.M110.186643
Permanent Link: http://hdl.handle.net/11104/0198639File Download Size Commentary Version Access Dong et al., 2011, JBC.pdf 8 922 KB Publisher’s postprint require - 5.0349341 - BTÚ 2011 RIV NL eng J - Journal Article
Ralph, S.J. - Rodriguez-Enriquez, S. - Neužil, Jiří - Moreno-Sanchez, R.
Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger.
Molecular Aspects of Medicine. Roč. 31, č. 1 (2010), s. 29-59. ISSN 0098-2997. E-ISSN 1872-9452
Institutional research plan: CEZ:AV0Z50520701
Keywords : Mitocans * reactive oxygen species * anti-cancer drugs
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 10.552, year: 2010 ; AIS: 3.25, rok: 2010
DOI: https://doi.org/10.1016/j.mam.2009.12.006
Permanent Link: http://hdl.handle.net/11104/0189607 - 6.0349092 - BTÚ 2011 RIV NL eng J - Journal Article
Ralph, S.J. - Rodruguez-Enriquez, S. - Neužil, Jiří - Saavedra, E. - Moreno-Sanchez, R.
The causes of cancer revisited: "Mitochondrial malignancy" and ROS-induced oncogenic transformation - Why mitochondria are targets for cancer therapy.
Molecular Aspects of Medicine. Roč. 31, č. 2 (2010), s. 145-170. ISSN 0098-2997. E-ISSN 1872-9452
Institutional research plan: CEZ:AV0Z50520701
Keywords : Carcinogenesis * mitocans * hypoxia
Subject RIV: FD - Oncology ; Hematology
Impact factor: 10.552, year: 2010 ; AIS: 3.25, rok: 2010
DOI: https://doi.org/10.1016/j.mam.2010.02.008
Permanent Link: http://hdl.handle.net/11104/0189422 - 7.0324996 - BTÚ 2009 RIV US eng J - Journal Article
Dong, L.F. - Freeman, R. - Liu, J. - Zobalová, Renata - Marin-Hernandez, A. - Stantic, M. - Rohlena, Jakub - Vališ, Karel - Rodriguez-Enriquez, S. - Butcher, B. - Goodwin, J. - Brunk, U.T. - Witting, P. K. - Moreno-Sanchez, R. - Scheffler, I.E. - Ralph, S.J. - Neužil, Jiří
Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II.
[Potlačení nádorového růstu in vivo mitokanem alfa-tokoferylsukcinátem vyžaduje respirační komplex II.]
Clinical Cancer Research. Roč. 15, č. 5 (2009), s. 1593-1600. ISSN 1078-0432. E-ISSN 1557-3265
R&D Projects: GA ČR(CZ) GA204/08/0811; GA AV ČR(CZ) IAA500520702
Institutional research plan: CEZ:AV0Z50520701
Keywords : SDHC-mutants * mitocans * mitochondrial complex II
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 6.747, year: 2009 ; AIS: 2.128, rok: 2009
DOI: https://doi.org/10.1158/1078-0432.CCR-08-2439
Permanent Link: http://hdl.handle.net/11104/0172563