Search results
- 1.0572870 - BTÚ 2024 RIV NL eng J - Journal Article
Bielcikova, Z. - Štursa, Jan - Křížová, L. - Dong, L. - Špaček, J. - Hlousek, S. - Vocka, M. - Rohlenová, Kateřina - Bartosova, O. - Černý, V. - Padrta, T. - Pesta, M. - Michálek, P. - Hubáčková, Soňa - Kološtová, K. - Pospíšilová, E. - Bobek, V. - Klezl, P. - Zobalová, Renata - Endaya, Berwini - Rohlena, Jakub - Petruzelka, L. - Werner, Lukáš - Neužil, Jiří
Mitochondrially targeted tamoxifen in patients with metastatic solid tumours: an open-label, phase I/Ib single-centre trial.
ECLINICALMEDICINE. Roč. 57, MAR 2023 (2023), č. článku 101873. E-ISSN 2589-5370
Institutional support: RVO:86652036
Keywords : Phase I * Ib clinical trial * Cancer * Mitochondrially targeted tamoxifen * Renal cell carcinoma
OECD category: General and internal medicine
Impact factor: 15.1, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S2589537023000500?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0343476 - 2.0571547 - BTÚ 2024 RIV US eng J - Journal Article
Dong, L. - Rohlena, Jakub - Zobalová, Renata - Nahácka, Zuzana - Rodriguez, A. - Berridge, M. V. V. - Neužil, Jiří
Mitochondria on the move: Horizontal mitochondrial transfer in disease and health.
Journal of Cell Biology. Roč. 222, č. 3 (2023), č. článku e202211044. ISSN 0021-9525. E-ISSN 1540-8140
R&D Projects: GA ČR(CZ) GA20-05942S; GA ČR(CZ) GX21-04607X; GA ČR(CZ) GA22-34507S; GA ČR(CZ) GA22-34507S; GA MZd(CZ) NU22-08-00160
Institutional support: RVO:86652036
Keywords : MESENCHYMAL STEM-CELLS * MULTIPOTENT STROMAL CELLS * TUNNELING NANOTUBES
OECD category: Cell biology
Impact factor: 7.8, year: 2022
Method of publishing: Open access
https://rupress.org/jcb/article/222/3/e202211044/213873/Mitochondria-on-the-move-Horizontal-mitochondrial
Permanent Link: https://hdl.handle.net/11104/0343553 - 3.0565970 - BTÚ 2023 RIV CH eng J - Journal Article
Nahácka, Zuzana - Novák, Jaromír - Zobalová, Renata - Neužil, Jiří
Miro proteins and their role in mitochondrial transfer in cancer and beyond.
Frontiers in Cell and Developmental Biology. Roč. 10, JUL 25 2022 (2022), č. článku 937753. ISSN 2296-634X. E-ISSN 2296-634X
R&D Projects: GA ČR(CZ) GX21-04607X; GA MŠMT(CZ) LM2018129; GA ČR(CZ) GA20-05942S
Institutional support: RVO:86652036
Keywords : cancer * mitochondria * intercellular transfer * Miro * respiration * migration * metastasis
OECD category: Developmental biology
Impact factor: 5.5, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fcell.2022.937753/full
Permanent Link: https://hdl.handle.net/11104/0337549 - 4.0561635 - BTÚ 2023 RIV FR eng J - Journal Article
Fialova, J. L. - Hönigová, K. - Raudenská, M. - Miksatkova, L. - Zobalová, Renata - Navrátil, J. - Smigova, Jana - Moturu, T. R. - Vicar, T. - Balvan, J. - Veselá, K. - Abramenko, N. - Kejik, Z. - Kaplánek, R. - Gumulec, J. - Rosel, D. - Martásek, P. - Brabek, J. - Jakubek, M. - Neužil, Jiří - Masarik, M.
Pentamethinium salts suppress key metastatic processes by regulating mitochondrial function and inhibiting dihydroorotate dehydrogenase respiration.
Biomedicine & Pharmacotherapy. Roč. 154, OCT 2022 (2022), č. článku 113582. ISSN 0753-3322. E-ISSN 1950-6007
Institutional support: RVO:86652036
Keywords : Dihydroorotate dehydrogenase * Metastasis * Mitochondria * Migration * Pentamethinium salts
OECD category: Pharmacology and pharmacy
Impact factor: 7.5, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0753332222009714?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0340715 - 5.0556526 - BTÚ 2023 RIV GB eng J - Journal Article
Štemberková-Hubáčková, Soňa - Zobalová, Renata - Dubišová, Maria - Šmigová, J. - Dvořáková, Šárka - Kořínková, Klára - Ezrová, Zuzana - Endaya, Berwini - Blažková, Kristýna - Vlčák, Erik - Brisudová, Petra - Le, Dan-Diem Thi - Juhás, Štefan - Rosel, D. - Kelemen, Daniela Cristina - Sovilj, Dana - Vačurová, Eliška - Čajka, Tomáš - Filimonenko, Vlada - Dong, L. - Anděra, Ladislav - Hozák, Pavel - Brabek, J. - Bielcikova, Z. - Štursa, Jan - Werner, Lukáš - Neužil, Jiří
Simultaneous targeting of mitochondrial metabolism and immune checkpoints as a new strategy for renal cancer therapy.
Clinical and Translational Medicine. Roč. 12, č. 3 (2022), č. článku e645. ISSN 2001-1326. E-ISSN 2001-1326
R&D Projects: GA ČR(CZ) GA20-05942S; GA ČR(CZ) GX21-04607X; GA ČR(CZ) GA18-02550S; GA ČR(CZ) GA19-08772S; GA MZd NU21-03-00195; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT LTC19048; GA MŠMT(CZ) LO1609; GA MŠMT(CZ) EF16_013/0001775
Grant - others:AV ČR(CZ) StrategieAV21/18
Program: StrategieAV
Institutional support: RVO:86652036 ; RVO:68378050 ; RVO:67985904 ; RVO:67985823
Keywords : Mitochondrially targeted tamoxifen * Renal cancer * Immunotherapy
OECD category: Pathology
Impact factor: 10.6, year: 2022
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/10.1002/ctm2.645
Permanent Link: http://hdl.handle.net/11104/0331774 - 6.0553062 - BTÚ 2023 RIV US eng J - Journal Article
Váňová Hadrava, Kateřina - Pang, Y. - Krobová, Linda - Kraus, Michal - Nahácka, Zuzana - Boukalová, Štěpána - Pack, S. - Zobalová, Renata - Zhu, J. - Huynh, T.-T. - Jochmanová, I. - Uher, O. - Hubáčková, Soňa - Dvořáková, Šárka - Garrett, T. - Ghayee, H. - Wu, X. - Schuster, Bjorn - Knapp, P. - Frysak, Z. - Hartmann, I. - Nilubol, N. - Černý, Jiří - Taieb, D. - Rohlena, Jakub - Neužil, Jiří - Yang, C. - Pacak, K.
Germline SUCLG2 Variants in Patients With Pheochromocytoma and Paraganglioma.
JNCI-Journal of the National Cancer Institute. Roč. 114, č. 1 (2022), č. článku djab158. ISSN 0027-8874. E-ISSN 1460-2105
R&D Projects: GA ČR(CZ) GA18-10832S; GA ČR GA19-20553S; GA ČR(CZ) GJ20-11724Y; GA ČR(CZ) GA20-05942S; GA MŠMT(CZ) LM2018130; GA MZd(CZ) NV17-30138A
Institutional support: RVO:86652036 ; RVO:68378050
Keywords : mutations * deficiency * penetrance * phenotype * genotype
OECD category: Oncology
Impact factor: 10.3, year: 2022
Method of publishing: Open access
https://academic.oup.com/jnci/article-abstract/114/1/130/6355591?redirectedFrom=fulltext&login=false
Permanent Link: https://hdl.handle.net/11104/0337608 - 7.0549057 - BTÚ 2022 RIV GB eng J - Journal Article
Nahácka, Zuzana - Zobalová, Renata - Dubišová, Maria - Rohlena, Jakub - Neužil, Jiří
Miro proteins connect mitochondrial function and intercellular transport.
Critical Reviews in Biochemistry and Molecular Biology and CRC Critical Reviews in Biochemistry. Roč. 56, č. 4 (2021), s. 401-425. ISSN 1040-9238. E-ISSN 1549-7798
R&D Projects: GA ČR(CZ) GA20-05942S; GA ČR(CZ) GX21-04607X; GA MZd(CZ) NV17-30138A; GA ČR GA19-20553S; GA ČR(CZ) GA20-18513S
Institutional support: RVO:86652036
Keywords : Mitochondria * mitophagy * endoplasmic reticulum
OECD category: Biochemistry and molecular biology
Impact factor: 8.697, year: 2021
Method of publishing: Limited access
https://www.tandfonline.com/doi/full/10.1080/10409238.2021.1925216?scroll=top&needAccess=true
Permanent Link: http://hdl.handle.net/11104/0325087 - 8.0542237 - BTÚ 2022 RIV GB eng J - Journal Article
Ezrová, Zuzana - Nahácka, Zuzana - Štursa, Jan - Werner, Lukáš - Vlčák, Erik - Králová Viziová, Petra - Berridge, M.V. - Sedláček, Radislav - Zobalová, Renata - Rohlena, Jakub - Boukalová, Štěpána - Neužil, Jiří
SMAD4 loss limits the vulnerability of pancreatic cancer cells to complex I inhibition via promotion of mitophagy.
Oncogene. Roč. 40, č. 14 (2021), s. 2539-2552. ISSN 0950-9232. E-ISSN 1476-5594
R&D Projects: GA MZd(CZ) NV16-31604A; GA ČR GA19-20553S; GA ČR(CZ) GA20-18513S; GA ČR(CZ) GJ20-11724Y; GA ČR(CZ) GA18-02550S; GA MŠMT(CZ) EF16_027/0008353; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT LO1220; GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) EF16_013/0001775; GA MŠMT(CZ) LM2018126; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:86652036 ; RVO:68378050
Keywords : biguanide derivative * reduced nicotinamide adenine dinucleotide dehydrogenase (ubiquinone) * Smad4 protein
OECD category: Genetics and heredity (medical genetics to be 3); Genetics and heredity (medical genetics to be 3) (UMG-J)
Impact factor: 8.756, year: 2021
Method of publishing: Limited access
https://www.nature.com/articles/s41388-021-01726-4?elqTrackId=c7cc7e8c0df94ff7a61453bf09cfb167
Permanent Link: http://hdl.handle.net/11104/0319702 - 9.0504151 - BTÚ 2020 RIV US eng J - Journal Article
Bajziková, Martina - Kovářová, Jaromíra - Coelho, Ana R. - Boukalová, Štěpána - Oh, S. - Rohlenová, Kateřina - Švec, David - Hubáčková, Soňa - Endaya, B. - Judasová, Kateřina - Bezawork-Geleta, A. - Klučková, Katarína - Chatre, L. - Zobalová, Renata - Nováková, Anna - Váňová, Kateřina - Ezrová, Zuzana - Maghzal, G. J. - Novais, Silvia Magalhaes - Olsinova, M. - Krobová, Linda - An, Y. J. - Davidová, Eliška - Nahácka, Zuzana - Sobol, Margaryta - Cunha-Oliveira, T. - Sandoval-Acuna, Cristian - Strnad, Hynek - Zhang, T. - Huynh, T. - Serafim, T. L. - Hozák, Pavel - Sardao, V. A. - Koopman, W. J. H. - Ricchetti, M. - Oliveira, P. J. - Kolář, František - Kubista, Mikael - Truksa, Jaroslav - Dvořáková-Hortová, Kateřina - Pacak, K. - Gürlich, R. - Stocker, R. - Zhou, Y. - Berridge, M.V. - Park, S. - Dong, L. - Rohlena, Jakub - Neužil, Jiří
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
Cell Metabolism. Roč. 29, č. 2 (2019), s. 399-416. ISSN 1550-4131. E-ISSN 1932-7420
R&D Projects: GA ČR GA15-02203S; GA ČR GA16-12719S; GA ČR GA17-20904S; GA ČR GA16-22823S; GA ČR(CZ) GA16-12816S; GA ČR(CZ) GA18-11275S; GA ČR(CZ) GA18-02550S; GA MZd(CZ) NV16-31604A; GA MZd(CZ) NV17-30138A; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) LM2015062; GA ČR(CZ) GJ18-24753Y; GA MŠMT(CZ) EF16_013/0001775
Institutional support: RVO:86652036 ; RVO:67985823 ; RVO:68378050
Keywords : ELECTRON-TRANSPORT CHAIN * PANCREATIC-CANCER * MITOCHONDRIA
OECD category: Cell biology; Physiology (including cytology) (FGU-C); Cell biology (UMG-J)
Impact factor: 21.567, year: 2019
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1550413118306466?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0295861 - 10.0492386 - BTÚ 2019 RIV GB eng J - Journal Article
Bezawork-Geleta, A. - Wen, H. - Dong, L. F. - Yan, B. - Vider, J. - Boukalová, Štěpána - Krobová, Linda - Váňová, Kateřina - Zobalová, Renata - Sobol, Margaryta - Hozák, Pavel - Novais, Silvia Magalhaes - Caisova, V. - Abaffy, Pavel - Naraine, Ravindra - Pang, Y. - Zaw, T. - Zhang, P. - Šindelka, Radek - Kubista, Mikael - Zuryn, S. - Molloy, M. P. - Berridge, M.V. - Pacak, K. - Rohlena, Jakub - Park, S. - Neužil, Jiří
Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints.
Nature Communications. Roč. 9, JUN 7 2018 (2018), č. článku 2221. E-ISSN 2041-1723
R&D Projects: GA ČR GA15-02203S; GA MZd NV17-30138A; GA ČR GA17-20904S; GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR GA16-22823S
Institutional support: RVO:86652036 ; RVO:68378050
Keywords : ELECTRON-TRANSPORT CHAIN * PYRUVATE-KINASE M2 * MITOCHONDRIAL-DNA MUTATIONS
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UMG-J)
Impact factor: 11.878, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286410