Search results
- 1.0543910 - FGÚ 2022 RIV GB eng J - Journal Article
Witte, F. - Ruiz-Orera, J. - Mattioli, C. C. - Blachut, S. - Adami, E. - Schulz, J. F. - Schneider-Lunitz, V. - Hummel, O. - Patone, G. - Mücke, M. B. - Šilhavý, Jan - Heinig, M. - Bottolo, L. - Sanchis, D. - Vingron, M. - Chekulaeva, M. - Pravenec, Michal - Hubner, N. - van Heesch, S.
A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.
Genome Biology. Roč. 22, č. 1 (2021), č. článku 191. ISSN 1474-760X. E-ISSN 1474-760X
Grant - others:AV ČR(CZ) AP1502
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:67985823
Keywords : genetic variation * trans QTL mapping * translational efficiency * ribosome profiling * cardiac hypertrophy * spontaneously hypertensive rats (SHR)
OECD category: Cardiac and Cardiovascular systems
Impact factor: 18.010, year: 2021
Method of publishing: Open access
https://doi.org/10.1186/s13059-021-02397-w
Permanent Link: http://hdl.handle.net/11104/0321014 - 2.0498683 - FGÚ 2019 RIV US eng J - Journal Article
Adriaens, M. E. - Lodder, E. M. - Moreno-Moral, A. - Šilhavý, Jan - Heinig, M. - Glinge, Ch. - Belterman, Ch. - Wolswinkel, R. - Petretto, E. - Pravenec, Michal - Remme, C. A. - Bezzina, C. R.
Systems Genetics Approaches in Rat Identify Novel Genes and Gene Networks Associated With Cardiac Conduction.
Journal of the American Heart Association. Roč. 7, č. 21 (2018), č. článku e009243. ISSN 2047-9980. E-ISSN 2047-9980
R&D Projects: GA ČR(CZ) GA13-10267S
Institutional support: RVO:67985823
Keywords : Eeectrocardiographic (ECG) parameters * rats * systems genetics
OECD category: Human genetics
Impact factor: 4.660, year: 2018
Permanent Link: http://hdl.handle.net/11104/0290968 - 3.0444838 - FGÚ 2016 RIV GB eng J - Journal Article
Schafer, S. - Adami, E. - Heinig, M. - Rodrigues, K. E. C. - Kreuchwig, F. - Šilhavý, Jan - van Heesch, S. - Simaite, D. - Rajewsky, N. - Cuppen, E. - Pravenec, Michal - Vingron, M. - Cook, S. A. - Hubner, N.
Translational regulation shapes the molecular landscape of complex disease phenotypes.
Nature Communications. Roč. 6, May 2015 (2015), s. 7200. E-ISSN 2041-1723
R&D Projects: GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204; GA MŠMT(CZ) 7E10067
Institutional support: RVO:67985823
Keywords : translational regulation * RNA sequencing * ribosome profiling * rat
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 11.329, year: 2015
Permanent Link: http://hdl.handle.net/11104/0247301 - 4.0443201 - FGÚ 2016 RIV GB eng J - Journal Article
Heinig, M. - Colomé-Tatché, M. - Taudt, A. - Rintisch, C. - Schafer, S. - Pravenec, Michal - Hubner, N. - Vingron, M. - Johannes, F.
histoneHMM: Differential analysis of histone modifications with broad genomic footprints.
BMC Bioinformatics. Roč. 16, Feb 22 (2015), s. 60. ISSN 1471-2105. E-ISSN 1471-2105
R&D Projects: GA MŠMT(CZ) 7E10067; GA ČR(CZ) GA13-04420S
Institutional support: RVO:67985823
Keywords : ChIP-seq * histone modifications * Hidden Markov model * computational biology * differential analysis
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.435, year: 2015
Permanent Link: http://hdl.handle.net/11104/0245945 - 5.0429012 - FGÚ 2015 RIV US eng J - Journal Article
Rintisch, C. - Heinig, M. - Bauerfeind, A. - Schafer, S. - Mieth, Ch. - Patone, G. - Hummel, O. - Chen, W. - Cook, S. - Cuppen, E. - Colomé-Tatché, M. - Johannes, F. - Jansen, R. C. - Neil, H. - Werner, M. - Pravenec, Michal - Vingron, M. - Hubner, N.
Natural variation of histone modification and its impact on gene expression in the rat genome.
Genome Research. Roč. 24, JUN (2014), s. 942-953. ISSN 1088-9051. E-ISSN 1549-5469
R&D Projects: GA MŠMT(CZ) 7E10067; GA ČR(CZ) GAP301/10/0290; GA MŠMT(CZ) LL1204
Institutional support: RVO:67985823
Keywords : ChIP-seq * histone modification * gene expression * genetic linkage analysis
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 14.630, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234214 - 6.0367313 - FGÚ 2012 RIV US eng J - Journal Article
Morrissey, C. - Grieve, I. - Heinig, M. - Atanur, S. - Petretto, E. - Pravenec, Michal - Hubner, N. - Aitman, T. J.
Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat.
Physiological Genomics. Roč. 43, č. 21 (2011), s. 1207-1218. ISSN 1094-8341. E-ISSN 1531-2267
R&D Projects: GA ČR(CZ) GA301/08/0166; GA MŠMT(CZ) ME10019
Institutional research plan: CEZ:AV0Z50110509
Keywords : eQTL * spontaneously hypertensive rat * quantitative trait transcript * sequence variation
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.735, year: 2011
Permanent Link: http://hdl.handle.net/11104/0202044 - 7.0348257 - FGÚ 2011 RIV GB eng J - Journal Article
Heinig, M. - Petretto, E. - Wallace, C. - Bottolo, L. - Rotival, M. - Lu, H. - Li, Y. - Sarwar, R. - Langley, S. R. - Bauerfeind, A. - Hummel, O. - Lee, Y. A. - Paskas, S. - Rintisch, C. - Saar, K. - Cooper, J. - Buchan, R. - Gray, C. C. - Cyster, J. G. - Erdmann, J. - Hengstenberg, C. - Maouche, S. - Ouwehand, W. H. - Rice, C. M. - Samani, N. J. - Schunkert, H. - Goodall, A. H. - Schulz, H. - Roider, H. G. - Vingron, M. - Blankenberg, S. - Münzel, T. - Zeller, T. - Szymczak, S. - Ziegler, A. - Tiret, L. - Smyth, D. J. - Pravenec, Michal - Aitman, T. J. - Cambien, F. - Clayton, D. - Todd, J. A. - Hubner, N. - Cook, S.A.
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
Nature. Roč. 467, č. 7314 (2010), s. 460-464. ISSN 0028-0836. E-ISSN 1476-4687
R&D Projects: GA MŠMT(CZ) 1M0520; GA ČR GAP301/10/0290
Institutional research plan: CEZ:AV0Z50110509
Keywords : IRF7 driven inflammatory network * Ebi2 * type 1 diabetes
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 36.104, year: 2010
Permanent Link: http://hdl.handle.net/11104/0188834 - 8.0342527 - FGÚ 2011 RIV US eng J - Journal Article
Petretto, E. - Bottolo, L. - Langley, S. R. - Heinig, M. - McDermott-Roe, Ch. - Sarwar, R. - Pravenec, Michal - Hübner, N. - Aitman, T. J. - Cook, S.A. - Richardson, S.
New Insights into the Genetic Control of Gene Expression using a Bayesian Multi-tissue Approach.
PLoS Computational Biology. Roč. 6, č. 4 (2010), e1000737. ISSN 1553-734X. E-ISSN 1553-7358
R&D Projects: GA ČR(CZ) GA301/08/0166; GA MŠMT(CZ) 1M0520; GA ČR GAP301/10/0290
Grant - others:EC(XE) LSHG-CT-2005-019015; Fondation Leducq(FR) 06 CVD 03
Institutional research plan: CEZ:AV0Z50110509
Keywords : expression profiles * Bayesian multi-tissue approach * genetical genomics
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.515, year: 2010
Permanent Link: http://hdl.handle.net/11104/0185241 - 9.0333701 - FGÚ 2010 RIV GB eng J - Journal Article
Tabakoff, B. - Saba, L. - Printz, M. - Flodman, P. - Hodgkinson, C. - Goldman, D. - Koob, G. - Richardson, H.N. - Kechris, K. - Bell, R.L. - Hübner, N. - Heinig, M. - Pravenec, Michal - Mangion, J. - Legault, L. - Dongier, M. - Conigrave, K.M. - Whitfield, J.B. - Saunders, J. - Grant, B. - Hoffman, P.L.
Genetical genomic determinants of alcohol consumption in rats and humans.
[Geneticko genomické determinanty konzumace alkoholu u potkanů a u lidí.]
BMC BIOLOGY. Roč. 7, - (2009), s. 70-70. E-ISSN 1741-7007
R&D Projects: GA MŠMT(CZ) 1M0520
Grant - others:Howard Hughes Medical Institute(US) 55005624
Institutional research plan: CEZ:AV0Z50110509
Keywords : alcohol consumption * rat * gene expression profiles
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.636, year: 2009
Permanent Link: http://hdl.handle.net/11104/0178630 - 10.0307224 - FGÚ 2008 RIV US eng J - Journal Article
Saar, K. - Beck, A. - Bihoreau, M. T. - Birney, E. - Brocklebank, D. - Chen, Y. - Cuppen, E. - Demonchy, S. - Dopazo, J. - Flicek, P. - Foglio, M. - Fujiyama, A. - Gut, I. G. - Gauguier, D. - Guigo, R. - Guryev, V. - Heinig, M. - Hummel, O. - Jahn, N. - Klages, S. - Křen, Vladimír - Kube, M. - Kuhl, H. - Kuramoto, T. - Pravenec, Michal
SNP and haplotype mapping for genetic analysis in the rat.
[SNP a haplotypové mapování pro genetické analýzy u potkana.]
Nature Genetics. Roč. 40, č. 5 (2008), s. 560-566. ISSN 1061-4036. E-ISSN 1546-1718
R&D Projects: GA MŠMT(CZ) 1P05ME791; GA MŠMT(CZ) 1M0520; GA MŠMT(CZ) ME08006
Grant - others:HHMI(US) 55005624; -(XE) LSHG-CT-2005-019015
Institutional research plan: CEZ:AV0Z50110509
Source of funding: N - Non-public resources ; R - Framework programmes of European Commission
Keywords : SNP * rat * complete map
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 30.259, year: 2008
Permanent Link: http://hdl.handle.net/11104/0160047