Search results
- 1.0563741 - MBÚ 2023 RIV CH eng J - Journal Article
Antošová, Z. - Podzimkova, N. - Tomala, Jakub - Augustýnková, K. - Sajnerová, K. - Nedvědová, E. - Šírová, Milada - de Martynoff, G. - Bechard, D. - Moebius, U. - Kovář, Marek - Špíšek, R. - Adkins, I.
SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity.
Frontiers in Immunology. Roč. 13, OCT 10 2022 (2022), č. článku 989895. ISSN 1664-3224. E-ISSN 1664-3224
Institutional support: RVO:61388971
Keywords : NK cells * antibody-dependent cytotoxicity * interleukin-15 * immunotherapy * therapeutic antibodies * rli-15
OECD category: Oncology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fimmu.2022.989895/full
Permanent Link: https://hdl.handle.net/11104/0335572 - 2.0550778 - MBÚ 2022 RIV GB eng J - Journal Article
Tomala, Jakub - Weberová, Petra - Tomalová, Barbora - Zákostelská, Zuzana - Sivák, Ladislav - Kovářová, Jiřina - Kovář, Marek
IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-gamma production by CD25(+)Foxp3(-) T cells.
eLife. Roč. 10, DEC 21 2021 (2021), č. článku e62432. ISSN 2050-084X. E-ISSN 2050-084X
R&D Projects: GA ČR GA13-12885S; GA ČR(CZ) GA18-12973S; GA MZd(CZ) NV19-03-00179
Institutional support: RVO:61388971
Keywords : il-2 * tolerance * responses * suppression * il-2 * anti-il-2 mab complexes * cd25 * T cells * IFN-gamma * lps * hyperreactivity * Mouse
OECD category: Immunology
Impact factor: 8.713, year: 2021
Method of publishing: Open access
https://elifesciences.org/articles/62432
Permanent Link: http://hdl.handle.net/11104/0326088 - 3.0542896 - MBÚ 2022 RIV NL eng J - Journal Article
Sivák, Ladislav - Šubr, Vladimír - Kovářová, Jiřina - Dvořáková, Barbora - Šírová, Milada - Říhová, Blanka - Randárová, Eva - Kraus, Michal - Tomala, Jakub - Studenovský, Martin - Vondráčková, Michaela - Sedláček, Radislav - Makovický, Peter - Fučíková, J. - Vošahlíková, Š. - Spíšek, R. - Kostka, Libor - Etrych, Tomáš - Kovář, Marek
Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.
Journal of Controlled Release. Roč. 332, APR 10 2021 (2021), s. 563-580. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) ED1.1.00/02.0109
Research Infrastructure: CCP - 90040
Institutional support: RVO:61388971 ; RVO:61389013 ; RVO:68378050
Keywords : Ritonavir derivate * Polymer carrier * pH-controlled release * Antitumor activity * Proteasome inhibition * STAT3 signaling inhibition
OECD category: Microbiology; Polymer science (UMCH-V)
Impact factor: 11.467, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0168365921001267
Permanent Link: http://hdl.handle.net/11104/0320232 - 4.0531980 - MBÚ 2021 RIV GB eng J - Journal Article
Hraboš, Dominik - Hnízdilová, Tereza - Tomala, Jakub - Uhlík, J. - Kovář, Marek
IL-7/alpha IL-7 mAb M25 immunocomplexes expand CD8(+) T cells but paradoxically abrogate the antitumor activity of CTLA-4 and PD-1 blockage.
Cytokine. Roč. 133, SEP 2020 (2020), č. článku 155174. ISSN 1043-4666. E-ISSN 1096-0023
R&D Projects: GA ČR(CZ) GA18-12973S
Institutional support: RVO:61388971
Keywords : IL-7 immunocomplexes * CTLA-4 * PD-1
OECD category: Microbiology
Impact factor: 3.861, year: 2020
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1043466620301903
Permanent Link: http://hdl.handle.net/11104/0310597 - 5.0494805 - MBÚ 2019 RIV US eng J - Journal Article
Spangler, J.B. - Trotta, E. - Tomala, Jakub - Peck, A. - Young, T.A. - Savvides, Ch.S. - Silveria, S. - Votavová, Petra - Salafsky, J. - Pande, V.S. - Kovář, Marek - Bluestone, J.A. - Garcia, K.Ch.
Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy.
Journal of Immunology. Roč. 201, č. 7 (2018), s. 2094-2106. ISSN 0022-1767. E-ISSN 1550-6606
R&D Projects: GA ČR GA13-12885S; GA ČR(CZ) GA18-12973S
Institutional support: RVO:61388971
Keywords : IL-2/ANTI-IL-2 MAB COMPLEXES * LOW-DOSE INTERLEUKIN-2 * CYTOKINE-RECEPTOR
OECD category: Microbiology
Impact factor: 4.718, year: 2018
Permanent Link: http://hdl.handle.net/11104/0289054File Download Size Commentary Version Access Spangler, Tomala-J. Immunol 18.pdf 7 2.6 MB Publisher’s postprint require - 6.0476224 - MBÚ 2018 RIV US eng J - Journal Article
Škopová, Karolína - Tomalová, Barbora - Kanchev, Ivan - Rossmann, Pavel - Švédová, Martina - Adkins, Irena - Bíbová, Ilona - Tomala, Jakub - Mašín, Jiří - Guiso, N. - Osička, Radim - Sedláček, Radislav - Kovář, Marek - Šebo, Peter
Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis.
Infection and Immunity. Roč. 85, č. 6 (2017), s. 1-22, č. článku e00937-16. ISSN 0019-9567. E-ISSN 1098-5522
R&D Projects: GA MZd(CZ) NV16-28126A; GA ČR(CZ) GA13-14547S; GA ČR GA13-12885S; GA ČR GA15-09157S; GA ČR(CZ) GAP302/12/0460; GA MŠMT(CZ) LM2015064; GA MŠMT(CZ) LM2015040
Institutional support: RVO:61388971 ; RVO:68378050
Keywords : Bordetella pertussis * adenylate cyclase toxin-hemolysin * cAMP intoxication
OECD category: Microbiology; Microbiology (UMG-J)
Impact factor: 3.256, year: 2017
Permanent Link: http://hdl.handle.net/11104/0272781File Download Size Commentary Version Access 125_Cyclic AMP-Elevating Capacity of Adenylate Cyclase.pdf 4 3.4 MB Publisher’s postprint require - 7.0475747 - MBÚ 2018 RIV US eng J - Journal Article
Adkins, I. - Sadílková, L. - Hradilová, N. - Tomala, Jakub - Kovář, Marek - Spíšek, R.
Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells.
OncoImmunology. Roč. 6, č. 5 (2017), s. 1-13, č. článku e1311433. ISSN 2162-4011
R&D Projects: GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971
Keywords : Antitumor immunity * calreticulin * cancer immunotherapy
OECD category: Microbiology
Impact factor: 5.503, year: 2017
Permanent Link: http://hdl.handle.net/11104/0272381File Download Size Commentary Version Access 152_Severe but not mild heat shock.pdf 5 2.3 MB Publisher’s postprint require - 8.0474097 - MBÚ 2018 RIV US eng J - Journal Article
Moserová, I. - Truxová, I. - Garg, A.D. - Tomala, Jakub - Agostinis, P. - Cartron, P.F. - Vošahlíková, Š. - Kovář, Marek - Spíšek, R. - Fučíková, J.
Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death.
OncoImmunology. Roč. 6, č. 1 (2017), s. 1-35, č. článku e1258505. ISSN 2162-4011
R&D Projects: GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971
Keywords : Caspases * ecto-CALR * ER stress
OECD category: Microbiology
Impact factor: 5.503, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271239File Download Size Commentary Version Access 152_Caspase-2 and oxidative stress underlie the immunogenic.pdf 3 1.2 MB Publisher’s postprint require - 9.0473875 - MBÚ 2018 RIV NL eng J - Journal Article
Šírová, Milada - Strohalm, Jiří - Chytil, Petr - Lidický, Ondřej - Tomala, Jakub - Říhová, Blanka - Etrych, Tomáš
The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel.
Journal of Controlled Release. Roč. 246, JAN 28 (2017), s. 1-11. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR(CZ) GA14-12742S; GA ČR(CZ) GA15-02986S; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109; GA MZd(CZ) NV16-28600A; GA ČR(CZ) GAP301/12/1254
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : Drug delivery * HPMA * Doxorubicin
OECD category: Immunology; Polymer science (UMCH-V)
Impact factor: 7.877, year: 2017
Permanent Link: http://hdl.handle.net/11104/0270992 - 10.0473557 - MBÚ 2018 RIV GB eng J - Journal Article
Sivák, Ladislav - Šubr, Vladimír - Tomala, Jakub - Říhová, Blanka - Strohalm, Jiří - Etrych, Tomáš - Kovář, Marek
Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate.
Biomaterials. Roč. 115, JAN 2017 (2017), s. 65-80. ISSN 0142-9612. E-ISSN 1878-5905
R&D Projects: GA ČR(CZ) GAP301/12/1254; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : Multidrug resistance * P-glycoprotein * Doxorubicin
OECD category: Microbiology; Polymer science (UMCH-V)
Impact factor: 8.806, year: 2017
Permanent Link: http://hdl.handle.net/11104/0270692