Search results
- 1.0543118 - ÚOCHB 2022 RIV US eng J - Journal Article
Kryštůfek, Robin - Šácha, Pavel - Starková, Jana - Brynda, Jiří - Hradilek, Martin - Tloušťová, Eva - Grzymska, J. - Rut, W. - Boucher, M. J. - Drag, M. - Majer, Pavel - Hájek, Miroslav - Řezáčová, Pavlína - Madhani, H. D. - Craik, C. S. - Konvalinka, Jan
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Journal of Medicinal Chemistry. Roč. 64, č. 10 (2021), s. 6706-6719. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : immunodeficiency virus HIV * in-vitro * virulence factors
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.0c02177
Permanent Link: http://hdl.handle.net/11104/0320402 - 2.0492282 - ÚOCHB 2019 RIV GB eng J - Journal Article
Humpolíčková, Jana - Weber, Jan - Starková, Jana - Mašínová, Eva - Günterová, Jana - Flaisigová, Iva - Konvalinka, Jan - Majerová, Taťána
Inhibition of the precursor and mature forms of HIV-1 protease as a tool for drug evaluation.
Scientific Reports. Roč. 8, Jul 11 (2018), č. článku 10438. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : human immunodeficiency virus * type 1 GagPol precursor * conformational ensembles
OECD category: Biochemistry and molecular biology
Impact factor: 4.011, year: 2018
https://www.nature.com/articles/s41598-018-28638-w
Permanent Link: http://hdl.handle.net/11104/0285806File Download Size Commentary Version Access 0492282.pdf 5 1.8 MB Publisher’s postprint open-access - 3.0463511 - ÚOCHB 2017 RIV GB eng J - Journal Article
Sivá, Monika - Svoboda, Michal - Veverka, Václav - Trempe, J. F. - Hofmann, K. - Kožíšek, Milan - Hexnerová, Rozálie - Sedlák, František - Belza, Jan - Brynda, Jiří - Šácha, Pavel - Hubálek, Martin - Starková, Jana - Flaisigová, Iva - Konvalinka, Jan - Grantz Šašková, Klára
Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.
Scientific Reports. Roč. 6, Jul 27 (2016), č. článku 30443. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GBP208/12/G016
Institutional support: RVO:61388963
Keywords : human DNA-damage-inducible 2 protein * proteasome * ubiquitin * retroviral protease-like domain
Subject RIV: CE - Biochemistry
Impact factor: 4.259, year: 2016
http://www.nature.com/articles/srep30443
Permanent Link: http://hdl.handle.net/11104/0262688File Download Size Commentary Version Access 0463511.pdf 4 7.5 MB Publisher’s postprint open-access - 4.0445391 - ÚOCHB 2016 RIV US eng J - Journal Article
Tykvart, Jan - Schimer, Jiří - Jančařík, Andrej - Bařinková, Jitka - Navrátil, Václav - Starková, Jana - Šrámková, Karolína - Konvalinka, Jan - Majer, Pavel - Šácha, Pavel
Design of Highly Potent Urea-Based, Exosite-Binding Inhibitors Selective for Glutamate Carboxypeptidase II.
Journal of Medicinal Chemistry. Roč. 58, č. 10 (2015), s. 4357-4363. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GBP208/12/G016; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : GCPII selective inhibitors * GCPIII * GCPII
Subject RIV: CE - Biochemistry
Impact factor: 5.589, year: 2015
Permanent Link: http://hdl.handle.net/11104/0247685 - 5.0431487 - ÚOCHB 2015 RIV GB eng J - Journal Article
Navrátil, Michal - Ptáček, Jakub - Šácha, Pavel - Starková, Jana - Lubkowski, J. - Bařinka, Cyril - Konvalinka, Jan
Structural and biochemical characterization of the folyl-poly-gamma-L-glutamate hydrolyzing activity of human glutamate carboxypeptidase II.
FEBS Journal. Roč. 281, č. 14 (2014), s. 3228-3242. ISSN 1742-464X. E-ISSN 1742-4658
R&D Projects: GA ČR GAP304/12/0847; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:OPPC(CZ) CZ.2.16/3.1.00/24016
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : arene-binding site * crystal structure * folate hydrolase 1 * H475Y(1561C -> T) * polymorphism * zinc metalloprotease
Subject RIV: CE - Biochemistry
Impact factor: 4.001, year: 2014
Permanent Link: http://hdl.handle.net/11104/0236127File Download Size Commentary Version Access Navratil_FEBSJ_281_3228_14.pdf 2 1.1 MB Publisher’s postprint require - 6.0377067 - ÚOCHB 2013 RIV US eng J - Journal Article
Tykvart, Jan - Šácha, Pavel - Bařinka, Cyril - Knedlík, Tomáš - Starková, Jana - Lubkowski, J. - Konvalinka, Jan
Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: Expression, characterization and structure analysis of recombinant human glutamate carboxypeptidase II.
Protein Expression and Purification. Roč. 82, č. 1 (2012), s. 106-115. ISSN 1046-5928. E-ISSN 1096-0279
R&D Projects: GA MŠMT 1M0508; GA MŠMT LC512
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520701
Keywords : affinity purification * biotin acceptor peptide * recombinant protein expression * biotin-protein ligase (BirA) * co-localization * PSMA
Subject RIV: CE - Biochemistry
Impact factor: 1.429, year: 2012
Permanent Link: http://hdl.handle.net/11104/0215606 - 7.0084096 - ÚOCHB 2008 RIV DK eng J - Journal Article
Bařinka, C. - Starková, Jana - Konvalinka, Jan - Lubkowski, J.
A high-resolution structure of ligand-free human glutamate carboxypeptidase II.
[Struktura volné lidské glutamátkarboxypeptidasy II s vysokým rozlišením.]
Acta Crystallographica Section F-Structural Biology and Crystallization Communications. F63, č. 3 (2007), s. 150-153. ISSN 1744-3091. E-ISSN 2053-230X
R&D Projects: GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z40550506
Keywords : human glutamate carboxypeptidase II * X-ray structure * prostate-cancer
Subject RIV: CE - Biochemistry
Impact factor: 0.645, year: 2007
Permanent Link: http://hdl.handle.net/11104/0147111