Search results

  1. 1.
    0383182 - BTÚ 2013 RIV NL eng J - Journal Article
    Rodriguez-Enriquez, S. - Hernandez-Esquivel, L. - Marin-Hernandez, A. - Dong, L.-F. - Akporiaye, E. - Neužil, Jiří - Ralph, S.J. - Moreno-Sanchez, R.
    Molecular mechanism for the selective impairment of cancer mitochondrial function by a mitochondrially targeted vitamin E analogue.
    Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1817, č. 9 (2012), s. 1597-1607. ISSN 0005-2728. E-ISSN 1879-2650
    R&D Projects: GA ČR GAP301/10/1937
    Institutional research plan: CEZ:AV0Z50520701
    Keywords : Mitochondria * respiratory complex II * vitamin E analogs
    Subject RIV: CE - Biochemistry
    Impact factor: 4.624, year: 2012
    DOI: https://doi.org/10.1016/j.bbabio.2012.05.005

    Permanent Link: http://hdl.handle.net/11104/0213201
     
     
  2. 2.
    0369512 - BTÚ 2012 RIV NL eng J - Journal Article
    Ito, K. - Scott, S.A. - Cutler, S. - Dong, L.-F. - Neužil, Jiří - Blanchard, H. - Ralph, S.J.
    Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress.
    Angiogenesis. Roč. 14, č. 3 (2011), s. 293-307. ISSN 0969-6970. E-ISSN 1573-7209
    Institutional research plan: CEZ:AV0Z50520701
    Keywords : Galectin-1 inhibitor * oxidative stress * angiogenesis
    Subject RIV: FD - Oncology ; Hematology
    Impact factor: 6.063, year: 2011
    DOI: https://doi.org/10.1007/s10456-011-9213-5

    Permanent Link: http://hdl.handle.net/11104/0203559
     
     
  3. 3.
    0369496 - BTÚ 2012 RIV US eng J - Journal Article
    Neužil, Jiří - Černý, Jiří - Dyason, J.C. - Dong, L.-F. - Ralph, S.J.
    Affinity of vitamin E analogues for the ubiquinone complex II site correlates with their toxicity to cancer cells.
    Molecular Nutrition & Food Research. Roč. 55, č. 10 (2011), s. 1543-1551. ISSN 1613-4125. E-ISSN 1613-4133
    Institutional research plan: CEZ:AV0Z50520701
    Keywords : Vitamin E analogues * mitochondrial complex II * modelling
    Subject RIV: CE - Biochemistry
    Impact factor: 4.301, year: 2011
    DOI: https://doi.org/10.1002/mnfr.201100066

    Permanent Link: http://hdl.handle.net/11104/0203545
     
     
  4. 4.
    0369494 - BTÚ 2012 RIV US eng J - Journal Article
    Ralph, S.J. - Moreno-Sanchez, R. - Neužil, Jiří - Rodriguez-Enriquez, S.
    Inhibitors of Succinate: Quinone Reductase/Complex II Regulate Production of Mitochondrial Reactive Oxygen Species and Protect Normal Cells from Ischemic Damage but Induce Specific Cancer Cell Death.
    Pharmaceutical Research. Roč. 28, č. 11 (2011), s. 2695-2730. ISSN 0724-8741. E-ISSN 1573-904X
    Institutional research plan: CEZ:AV0Z50520701
    Keywords : Mitocans * SDH/Complex II * mitochondrial ROS production
    Subject RIV: CE - Biochemistry
    Impact factor: 4.093, year: 2011
    DOI: https://doi.org/10.1007/s11095-011-0566-7

    Permanent Link: http://hdl.handle.net/11104/0006745
     
     
  5. 5.
    0369481 - BTÚ 2012 RIV US eng J - Journal Article
    Rohlena, Jakub - Dong, L.-F. - Ralph, S.J. - Neužil, Jiří
    Anticancer Drugs Targeting the Mitochondrial Electron Transport Chain.
    Antioxidants & Redox Signaling. Roč. 15, č. 12 (2011), s. 2951-2974. ISSN 1523-0864. E-ISSN 1557-7716
    R&D Projects: GA AV ČR(CZ) KAN200520703
    Institutional research plan: CEZ:AV0Z50520701
    Keywords : Targets for anticancer drugs * mitochondrial electron transport chain * mitocans
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 8.456, year: 2011
    DOI: https://doi.org/10.1089/ars.2011.3990

    Permanent Link: http://hdl.handle.net/11104/0203533
    FileDownloadSizeCommentaryVersionAccess
    Rohlena et al., 2011, ARS 15, 2951.pdf5593.5 KBPublisher’s postprintrequire
     
     
  6. 6.
    0360075 - BTÚ 2012 RIV US eng J - Journal Article
    Dong, L.-F. - Jameson, V.J.A. - Tilly, D. - Procházka, L. - Rohlena, Jakub - Vališ, Karel - Truksa, Jaroslav - Zobalová, Renata - Mandavian, E. - Klučková, Katarína - Stantic, M. - Štursa, Jan - Freeman, R. - Witting, P.K. - Norberg, E. - Goodwin, J. - Salvatore, B.A. - Novotná, Jana - Turánek, J. - Ledvina, Miroslav - Hozák, Pavel - Zhivotovsky, B. - Coster, M. - Ralph, S.J. - Smith, R.A.J. - Neužil, Jiří
    Mitochondrial targeting of [alpha]-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy.
    Free Radical Biology and Medicine. Roč. 50, č. 11 (2011), s. 1546-1555. ISSN 0891-5849. E-ISSN 1873-4596
    R&D Projects: GA ČR GA204/08/0811; GA ČR GAP301/10/1937; GA AV ČR IAA500520702; GA AV ČR KAN200520703; GA AV ČR KJB500970904; GA AV ČR KAN200100801
    Institutional research plan: CEZ:AV0Z50520701; CEZ:AV0Z50520514; CEZ:AV0Z4055905
    Keywords : Triphenyl phosphonium * reactive oxygen species * apoptosis
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 5.423, year: 2011
    DOI: https://doi.org/10.1016/j.freeradbiomed.2011.02.032

    Permanent Link: http://hdl.handle.net/11104/0197713
    FileDownloadSizeCommentaryVersionAccess
    Dong et al., 2011, Free Radic Biol Chem.pdf5444.4 KBPublisher’s postprintrequire
     
     
  7. 7.
    0358947 - BTÚ 2011 RIV US eng J - Journal Article
    Vališ, Karel - Procházka, L. - Bouřa, Evžen - Chladová, Jaromíra - Obšil, T. - Rohlena, Jakub - Truksa, Jaroslav - Dong, L.F. - Ralph, S.J. - Neužil, Jiří
    Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner.
    Cancer Research. Roč. 71, č. 3 (2011), s. 946-954. ISSN 0008-5472. E-ISSN 1538-7445
    R&D Projects: GA AV ČR(CZ) KJB500970904; GA ČR(CZ) GA204/08/0811; GA AV ČR(CZ) IAA500520702; GA ČR GAP301/10/1937
    Institutional research plan: CEZ:AV0Z50520701; CEZ:AV0Z50110509
    Keywords : Mst1 kinase * FoxO proteins * alpha-tocopheryl succinate
    Subject RIV: FD - Oncology ; Hematology
    Impact factor: 7.856, year: 2011
    DOI: https://doi.org/10.1158/0008-5472.CAN-10-2203

    Permanent Link: http://hdl.handle.net/11104/0196844
     
     
  8. 8.
    0349341 - BTÚ 2011 RIV NL eng J - Journal Article
    Ralph, S.J. - Rodriguez-Enriquez, S. - Neužil, Jiří - Moreno-Sanchez, R.
    Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger.
    Molecular Aspects of Medicine. Roč. 31, č. 1 (2010), s. 29-59. ISSN 0098-2997. E-ISSN 1872-9452
    Institutional research plan: CEZ:AV0Z50520701
    Keywords : Mitocans * reactive oxygen species * anti-cancer drugs
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 10.552, year: 2010
    DOI: https://doi.org/10.1016/j.mam.2009.12.006

    Permanent Link: http://hdl.handle.net/11104/0189607
     
     
  9. 9.
    0349092 - BTÚ 2011 RIV NL eng J - Journal Article
    Ralph, S.J. - Rodruguez-Enriquez, S. - Neužil, Jiří - Saavedra, E. - Moreno-Sanchez, R.
    The causes of cancer revisited: "Mitochondrial malignancy" and ROS-induced oncogenic transformation - Why mitochondria are targets for cancer therapy.
    Molecular Aspects of Medicine. Roč. 31, č. 2 (2010), s. 145-170. ISSN 0098-2997. E-ISSN 1872-9452
    Institutional research plan: CEZ:AV0Z50520701
    Keywords : Carcinogenesis * mitocans * hypoxia
    Subject RIV: FD - Oncology ; Hematology
    Impact factor: 10.552, year: 2010
    DOI: https://doi.org/10.1016/j.mam.2010.02.008

    Permanent Link: http://hdl.handle.net/11104/0189422
     
     
  10. 10.
    0349091 - BTÚ 2011 RIV NL eng J - Journal Article
    Procházka, L. - Dong, L.F. - Vališ, Karel - Freeman, R. - Ralph, S.J. - Turánek, J. - Neužil, Jiří
    Alpha-Tocopheryl succinate causes mitochondrial permeabilization by preferential formation of Bak channels.
    Apoptosis. Roč. 15, č. 7 (2010), s. 782-794. ISSN 1360-8185. E-ISSN 1573-675X
    R&D Projects: GA AV ČR(CZ) KAN200520703; GA AV ČR(CZ) IAA500520702; GA AV ČR(CZ) IAA500520602
    Institutional research plan: CEZ:AV0Z50520701
    Keywords : Vitamin E succinate * apoptosis * Noxa-Bak
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 4.397, year: 2010
    DOI: https://doi.org/10.1007/s10495-010-0482-z

    Permanent Link: http://hdl.handle.net/11104/0189421
     
     

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