Search results
- 1.0487071 - ÚOCHB 2018 CA eng A - Abstract
Jílková, Adéla - Rubešová, Petra - Řezáčová, Pavlína - Fanfrlík, Jindřich - Fajtová, Pavla - Brynda, Jiří - Lepšík, Martin - Horn, Martin - McKerrow, J. H. - Caffrey, C. R. - Mareš, Michael
Exploring druggable hot spots in Schistosoma mansoni cathepsin B1 for structure-based design of vinyl sulfone inhibitors.
IPS 2017. 10th General Meeting of the International Proteolysis Society. Banff: International Proteolysis Society, 2017. s. 152.
[IPS 2017. General Meeting of the International Proteolysis Society /10./. 28.10.2017-02.11.2017, Banff]
R&D Projects: GA MŠMT(CZ) LH15040; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : Schistosoma mansoni * SmCB1
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0281755 - 2.0480574 - ÚOCHB 2018 GB eng A - Abstract
Jílková, Adéla - Marešová, Lucie - Rubešová, Petra - Fajtová, Pavla - Horn, Martin - Řezáčová, Pavlína - Brynda, Jiří - McKerrow, J. H. - Caffrey, C. R. - Mareš, Michael
Structural basis for vinyl sulfone inhibition of the SmCB1 drug target from the human blood fluke.
FEBS Journal. Roč. 284, Suppl 1 (2017), s. 191. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /42./ From Molecules to Cells and Back. 10.09.2017-14.09.2017, Jerusalem]
Institutional support: RVO:61388963
Keywords : schistosomiasis * cathepsin B1 * inhibitor
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0276325 - 3.0471340 - ÚOCHB 2017 IT eng A - Abstract
Jílková, Adéla - Rubešová, Petra - Fajtová, Pavla - Horn, Martin - Řezáčová, Pavlína - Brynda, Jiří - McKerrow, J. H. - Caffrey, C. R. - Mareš, Michael
Structural basis for vinyl sulfone inhibition of the SmCB1 drug target from the human blood fluke.
Gordon Research Conference on Proteolytic Enzymes & Their Inhibitors. Barga: GRC, 2016.
[Gordon Research Conference on Proteolytic Enzymes & Their Inhibitors. 26.06.2016-01.07.2016, Barga]
R&D Projects: GA MŠMT(CZ) LH15040; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : schistosomiasis * inhibitor * cathepsin B1
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0268802 - 4.0443483 - ÚOCHB 2016 CZ eng A - Abstract
Jílková, Adéla - Horn, Martin - Řezáčová, Pavlína - Marešová, Lucie - Fajtová, Pavla - Brynda, Jiří - Vondrášek, Jiří - McKerrow, J. H. - Caffrey, C. R. - Mareš, Michael
Activation route of the Schistosoma mansoni cathepsin B1 drug target.
Materials Structure in Chemistry, Biology, Physics and Technology. Czech and Slovak Crystallographic Association. Roč. 22, č. 1 (2015), s. 39. ISSN 1211-5894.
[Discussions in Structural Molecular Biology. Annual Meeting of the Czech Society for Structural Biology /13./. 19.03.2015-21.03.2015, Nové Hrady]
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : Schistosoma mansoni * cathepsin B1 * sulfated polysaccharides
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0246295 - 5.0385316 - ÚOCHB 2013 GR eng A - Abstract
Jílková, Adéla - Řezáčová, Pavlína - Lepšík, Martin - Horn, Martin - Váchová, Jana - Fanfrlík, Jindřich - Brynda, Jiří - McKerrow, J. H. - Caffrey, C. R. - Mareš, Michael
Structural basis for inhibition of the cathepsin B drug target from the human blood fluke, Schistosoma mansoni.
Molecular and Cellular Biology of Helminth Parasites. 7th International Conference. Hydra: -, 2012. s. 60-60.
[Molecular and Cellular Biology of Helminth Parasites. International Conference /7./. 02.09.2012-07.09.2012, Hydra]
R&D Projects: GA MŠMT LH12023; GA ČR GA203/09/1585
Institutional support: RVO:61388963
Keywords : cathepsin B1 * Schistosoma * protease * structures
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0214605 - 6.0369840 - ÚOCHB 2012 US eng A - Abstract
Jílková, Adéla - Řezáčová, Pavlína - Lepšík, Martin - Horn, Martin - Váchová, Jana - Fanfrlík, Jindřich - Brynda, Jiří - McKerrow, J. H. - Caffrey, C. R. - Mareš, Michael
Structural basis for inhibition of the cathepsin B drug target from the human blood fluke, Schistosoma mansoni.
Seventh General Meeting of the International Proteolysis Society. San Diego: International Proteolysis Society, 2011. s. 98-98.
[General Meeting of the International Proteolysis Society /7./. 16.10.2011-20.10.2011, San Diego]
R&D Projects: GA ČR GA203/09/1585; GA ČR GAP208/11/0295
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520514
Keywords : cathepsin B1 * Schistosoma * crystal structures * inhibitors
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0203812 - 7.0336472 - BC 2010 RIV GB eng A - Abstract
Franta, Zdeněk - Pěničková, Helena - Dvorak, J. - Schneider, E. I. - Horn, Martin - Mareš, Michael - Sojka, Daniel - McKerrow, J. H. - Caffrey, C. R. - Kopáček, Petr
Functional expression and characterization of cathepsin B and L from the gut of the tick Ixodes ricinus.
FEBS Journal. Roč. 276, S1 (2009), s. 309-309. ISSN 1742-464X. E-ISSN 1742-4658.
[34th FEBS Congress: Life's Molecular Interactions. 04.07.2009-09.07.2009, Prague]
R&D Projects: GA AV ČR IAA600960910; GA MŠMT(CZ) LC06009
Institutional research plan: CEZ:AV0Z60220518; CEZ:AV0Z40550506
Keywords : cathepsin B and L * Ixodes ricinus * functionl expresssion
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0180696 - 8.0093184 - ÚOCHB 2008 GR eng A - Abstract
Horn, Martin - Sojka, Daniel - Jílková, Adéla - Franta, Zdeněk - Zikmundová, Martina - Bogyo, M. - McKerrow, J. H. - Caffrey, C. R. - Kopáček, Petr - Mareš, Michael
Semilarity of hemoglobin proteolysis in ticks and blood flukes.
[Podobnost hemoglobinové proteolýzy u klíštěte a krevničky.]
5th General Meeting of the International Proteolysis Society. Patras: University of Patras, 2007. s. 200.
[General Meeting of the International Proteolysis Society /5./. 20.10.2007-24.10.2007, Patras]
R&D Projects: GA AV ČR KJB400550516; GA ČR GA206/06/0865
Grant - others:NIH(US) AI-053247
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z60220518
Keywords : tick * blood fluke * peptidases * hemoglobin
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0153294