Search results
- 1.0539841 - MBÚ 2021 RIV US eng J - Journal Article
Steiningerová, Lucie - Kameník, Zdeněk - Gažák, Radek - Kadlčík, Stanislav - Bashiri, G. - Man, Petr - Kuzma, Marek - Pavlíková, Magdaléna - Janata, Jiří
Different Reaction Specificities of F420H2-Dependent Reductases Facilitate Pyrrolobenzodiazepines and Lincomycin To Fit Their Biological Targets.
Journal of the American Chemical Society. Roč. 142, č. 7 (2020), s. 3440-3448. ISSN 0002-7863. E-ISSN 1520-5126
R&D Projects: GA ČR(CZ) GJ17-13436Y; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LQ1604
Research Infrastructure: CIISB - 90043
Institutional support: RVO:61388971
Keywords : antibody-drug conjugate * antitumor antibiotics * sequence-analysis * gene-cluster * biosynthesis * strain * lincosamides * tuberculosis * tomaymycin
OECD category: Microbiology
Impact factor: 15.419, year: 2020
Method of publishing: Limited access
https://pubs.acs.org/doi/abs/10.1021/jacs.9b11234
Permanent Link: http://hdl.handle.net/11104/0317538 - 2.0507230 - MBÚ 2019 RIV JP eng J - Journal Article
Vimberg, Vladimír - Gažák, Radek - Szucs, Z. - Borbas, A. - Herczegh, P. - Cavanagh, J.P. - Zieglerová, Leona - Závora, J. - Adámková, V. - Balíková Novotná, Gabriela
Fluorescence assay to predict activity of the glycopeptide antibiotics.
Journal of Antibiotics. Roč. 72, č. 2 (2019), s. 114-117. ISSN 0021-8820. E-ISSN 1881-1469
R&D Projects: GA MZd(CZ) NV15-28807A; GA MŠMT(CZ) ED1.100/02.0109
Institutional support: RVO:61388971
Keywords : teicoplanin pseudoaglycon derivatives
OECD category: Microbiology
Impact factor: 2.668, year: 2019
Method of publishing: Limited access
https://www.nature.com/articles/s41429-018-0120-5
Permanent Link: http://hdl.handle.net/11104/0298264 - 3.0499560 - MBÚ 2019 RIV GB eng J - Journal Article
Janata, Jiří - Kameník, Zdeněk - Gažák, Radek - Kadlčík, Stanislav - Najmanová, Lucie
Biosynthesis and incorporation of an alkylproline-derivative (APD) precursor into complex natural products.
Natural Product Reports. Roč. 35, č. 3 (2018), s. 257-289. ISSN 0265-0568. E-ISSN 1460-4752
R&D Projects: GA ČR(CZ) GJ17-13436Y; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971
Keywords : synthetase adenylation domains * marine-derived actinomycete * peptidyl transferase center
OECD category: Microbiology
Impact factor: 11.876, year: 2018
Permanent Link: http://hdl.handle.net/11104/0291757File Download Size Commentary Version Access APD review published.pdf 12 4.3 MB Author´s preprint require - 4.0499534 - MBÚ 2019 RIV GB eng J - Journal Article
Kameník, Zdeněk - Gažák, Radek - Kadlčík, Stanislav - Steiningerová, Lucie - Rynd, Vít - Janata, Jiří
C-C bond cleavage in biosynthesis of 4-alkyl-L-proline precursors of lincomycin and anthramycin cannot precede C-methylation.
Nature Communications. Roč. 9, AUG 9 (2018), č. článku 3167. E-ISSN 2041-1723
R&D Projects: GA ČR(CZ) GJ17-13436Y
Institutional support: RVO:61388971
Keywords : Gene-cluster * Homolgy
OECD category: Microbiology
Impact factor: 11.878, year: 2018
Permanent Link: http://hdl.handle.net/11104/0291730File Download Size Commentary Version Access Kamenik_et_al-2018-Nature_Communications.pdf 7 1 MB Author´s preprint require - 5.0483944 - MBÚ 2018 RIV US eng J - Journal Article
Vobruba, Šimon - Kadlčík, Stanislav - Gažák, Radek - Janata, Jiří
Evolution-guided adaptation of an adenylation domain substrate specificity to an unusual amino acid.
PLoS ONE. Roč. 12, č. 12 (2017), č. článku e0189684. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR(CZ) GJ17-13436Y; GA MŠMT(CZ) LQ1604
Institutional support: RVO:61388971
Keywords : NONRIBOSOMAL PEPTIDE SYNTHETASES * BIOSYNTHETIC GENE-CLUSTER * LINCOSAMIDE ANTIBIOTICS
OECD category: Microbiology
Impact factor: 2.766, year: 2017
Permanent Link: http://hdl.handle.net/11104/0279118File Download Size Commentary Version Access 111_Evolution-guided adaptation of an adenylation domain substrat.pdf 8 1.6 MB Publisher’s postprint require - 6.0477899 - MBÚ 2018 RIV US eng J - Journal Article
Kameník, Zdeněk - Kadlčík, Stanislav - Gažák, Radek - Vobruba, Šimon - Palánová, Lucie - Kuzma, Marek - Janata, Jiří
Diversity of Alkylproline Moieties in Pyrrolobenzodiazepines Arises from Postcondensation Modifications of a Unified Building Block.
ACS Chemical Biology. Roč. 12, č. 8 (2017), s. 1993-1998. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA ČR(CZ) GJ17-13436Y; GA MŠMT(CZ) LQ1604
Institutional support: RVO:61388971
Keywords : ANTIBODY-DRUG CONJUGATE * BIOSYNTHETIC GENE-CLUSTER * SEQUENCE-ANALYSIS
OECD category: Microbiology
Impact factor: 4.592, year: 2017
Permanent Link: http://hdl.handle.net/11104/0274106File Download Size Commentary Version Access Kamenik2017_APD in PBD_ACS chem biol.pdf 7 2 MB Publisher’s postprint require - 7.0462551 - MBÚ 2017 RIV US eng J - Journal Article
Karas, D. - Gažák, Radek - Valentová, Kateřina - Chambers, Christopher S. - Pivodová, V. - Biedermann, David - Křenková, Alena - Oborná, I. - Kuzma, Marek - Cvačka, Josef - Ulrichová, J. - Křen, Vladimír
Effects of 2,3-Dehydrosilybin and Its Galloyl Ester and Methyl Ether Derivatives on Human Umbilical Vein Endothelial Cells.
Journal of Natural Products. Roč. 79, č. 4 (2016), s. 812-820. ISSN 0163-3864. E-ISSN 1520-6025
R&D Projects: GA ČR(CZ) GA15-03037S; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LD15084
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : ANGIOGENESIS IN-VITRO * SILYBIN * SILYMARIN
Subject RIV: CE - Biochemistry
Impact factor: 3.281, year: 2016
Permanent Link: http://hdl.handle.net/11104/0261986File Download Size Commentary Version Access 114_EffectsOf23DehydrosilybinAnditsGalloylEsters.pdf 5 1.4 MB Publisher’s postprint require - 8.0462120 - MBÚ 2017 RIV GB eng J - Journal Article
Kameník, Zdeněk - Kadlčík, Stanislav - Radojevič, Bojana - Jirásková, Petra - Kuzma, Marek - Gažák, Radek - Najmanová, Lucie - Kopecký, J. - Janata, Jiří
Deacetylation of mycothiol-derived 'waste product' triggers the last biosynthetic steps of lincosamide antibiotics.
Chemical Science. Roč. 7, č. 1 (2016), s. 430-435. ISSN 2041-6520. E-ISSN 2041-6539
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) EE2.3.30.0003
Institutional support: RVO:61388971
Keywords : STREPTOMYCES-LINCOLNENSIS * LINCOMYCIN-B * INTERMEDIATE
Subject RIV: CC - Organic Chemistry
Impact factor: 8.668, year: 2016
Permanent Link: http://hdl.handle.net/11104/0261641File Download Size Commentary Version Access 111_Deacetylation of mycothiol-derived 'waste product'.pdf 4 935.4 KB Publisher’s postprint require - 9.0462077 - MBÚ 2017 RIV CH eng J - Journal Article
Jirásková, Petra - Gažák, Radek - Kameník, Zdeněk - Steiningerová, Lucie - Najmanová, Lucie - Kadlčík, Stanislav - Novotná, Jitka - Kuzma, Marek - Janata, Jiří
New Concept of the Biosynthesis of 4-Alkyl-L-Proline Precursors of Lincomycin, Hormaomycin, and Pyrrolobenzodiazepines: Could a gamma-Glutamyltransferase Cleave the C-C Bond?
Frontiers in Microbiology. Roč. 7, Mar 7 (2016), s. 276. ISSN 1664-302X. E-ISSN 1664-302X
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) EE2.3.30.0003
Institutional support: RVO:61388971
Keywords : anticancer drug * antibiotics * natural product biosynthesis
Subject RIV: EE - Microbiology, Virology
Impact factor: 4.076, year: 2016
Permanent Link: http://hdl.handle.net/11104/0261645File Download Size Commentary Version Access 111_New Concept of the Biosynthesis.pdf 2 1.8 MB Publisher’s postprint require - 10.0452974 - MBÚ 2016 RIV US eng J - Journal Article
Vimberg, Vladimír - Kuzma, Marek - Stodůlková, Eva - Novák, Petr - Bednárová, Lucie - Šulc, Miroslav - Gažák, Radek
Hydnocarpin-Type Flavonolignans: Semisynthesis and Inhibitory Effects on Staphylococcus aureus Biofilm Formation.
Journal of Natural Products. Roč. 78, č. 8 (2015), s. 2095-2103. ISSN 0163-3864. E-ISSN 1520-6025
R&D Projects: GA MŠMT(CZ) EE2.3.30.0003; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : ENZYMATIC KINETIC RESOLUTION * SILYBIN DIASTEREOISOMERS * SEED HULLS
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 3.662, year: 2015
Permanent Link: http://hdl.handle.net/11104/0253854File Download Size Commentary Version Access Vimberg_2015_JNatProd.pdf 6 738.9 KB Publisher’s postprint require