Search results
- 1.0572804 - FGÚ 2024 RIV US eng J - Journal Article
Abramová, Vera - Leal Alvarado, Vanessa - Hill, M. - Smejkalová, Tereza - Malý, Michal - Valeš, Karel - Dittert, Ivan - Božíková, Paulina - Kysilov, Bohdan - Hrčka Krausová, Barbora - Vyklický, Vojtěch - Balík, Aleš - Fili, Klevinda - Kořínek, Miloslav - Chodounská, Hana - Kudová, Eva - Číž, D. - Martinovič, J. - Černý, Jiří - Bartůněk, Petr - Vyklický ml., Ladislav
Effects of Pregnanolone Glutamate and Its Metabolites on GABAA and NMDA Receptors and Zebrafish Behavior.
ACS Chemical Neuroscience. Roč. 14, č. 10 (2023), s. 1870-1883. ISSN 1948-7193. E-ISSN 1948-7193
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA MŠMT LM2023052; GA ČR(CZ) GA23-04922S; GA TA ČR(CZ) TN02000109
Research Infrastructure: CZ-OPENSCREEN IV - 90252
Institutional support: RVO:67985823 ; RVO:86652036 ; RVO:61388963 ; RVO:68378050
Keywords : negative allosteric modulator * thigmotaxis * steroid * glutamate * zebrafish
OECD category: Neurosciences (including psychophysiology; Neurosciences (including psychophysiology (UOCHB-X); Biochemistry and molecular biology (UMG-J); Biochemistry and molecular biology (BTO-N)
Impact factor: 5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acschemneuro.3c00131
Permanent Link: https://hdl.handle.net/11104/0343402 - 2.0558805 - FGÚ 2023 RIV GB eng J - Journal Article
Rudolfová, V. - Petrásek, Tomáš - Antošová, E. - Frynta, D. - Landová, E. - Valeš, Karel - Nekovářová, Tereza
Inter-individual differences in laboratory rats as revealed by three behavioural tasks.
Scientific Reports. Roč. 12, č. 1 (2022), č. článku 9361. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA ČR(CZ) GA22-15096S
Institutional support: RVO:67985823
Keywords : elevated plus-maze * open-field behavior * Morris water maze * animal-model * mice * traits
OECD category: Neurosciences (including psychophysiology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41598-022-13288-w
Permanent Link: https://hdl.handle.net/11104/0332649 - 3.0558392 - FGÚ 2023 RIV CH eng J - Journal Article
Židó, M. - Kačer, D. - Valeš, Karel - Svobodová, Z. - Zimová, D. - Štětkářová, I.
Metabolomics of Cerebrospinal Fluid in Multiple Sclerosis Compared With Healthy Controls: A Pilot Study.
Frontiers in Neurology. Roč. 13, May 26 (2022), č. článku 874121. ISSN 1664-2295. E-ISSN 1664-2295
Institutional support: RVO:67985823
Keywords : multiple sclerosis * CSF * metabolomics * biomarker * fatty acids * amino acids * arginine
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://doi.org/10.3389/fneur.2022.874121
Permanent Link: http://hdl.handle.net/11104/0332206 - 4.0557063 - FGÚ 2023 RIV NL eng J - Journal Article
Kolář, D. - Kletečková, L. - Skálová, K. - Brožka, Hana - Kalous, M. - Valeš, Karel
Glycolytic and Krebs cycle enzymes activity in rat prefrontal cortex, hippocampus, and striatum after single and repeated NMDA inhibition by MK-801.
Neurotoxicology. Roč. 90, May (2022), s. 35-47. ISSN 0161-813X. E-ISSN 1872-9711
R&D Projects: GA ČR(CZ) GA18-09296S; GA MZd(CZ) EF16_025/0007444; GA MZd(CZ) NU20-04-00389; GA ČR(CZ) GA22-15096S
Institutional support: RVO:67985823
Keywords : energy metabolism * hexokinase * lactate dehydrogenase * citrate synthase * malate dehydrogenase * schizophrenia
OECD category: Pharmacology and pharmacy
Impact factor: 3.4, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.neuro.2022.02.005
Permanent Link: http://hdl.handle.net/11104/0331183 - 5.0551648 - ÚOCHB 2023 RIV CH eng J - Journal Article
Kudová, Eva - Mareš, Pavel - Hill, M. - Vondráková, Kateřina - Tsenov, Grygoriy - Chodounská, Hana - Kubová, Hana - Valeš, Karel
The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains.
Pharmaceuticals. Roč. 15, č. 1 (2022), č. článku 49. E-ISSN 1424-8247
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA MZd(CZ) NU20-04-00389
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : neurosteroids * anticonvulsant * zuranolone * NMDA * GABA * metabolomics
OECD category: Organic chemistry
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1424-8247/15/1/49
Permanent Link: http://hdl.handle.net/11104/0326887 - 6.0544687 - FGÚ 2022 RIV CH eng J - Journal Article
Holubová, K. - Chvojková, M. - Hrčka Krausová, Barbora - Vyklický, Vojtěch - Kudová, Eva - Chodounská, Hana - Vyklický ml., Ladislav - Valeš, Karel
Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia.
Biomolecules. Roč. 11, č. 7 (2021), č. článku 1026. E-ISSN 2218-273X
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA ČR(CZ) GA20-17945S; GA ČR(CZ) GA18-09296S; GA MZd(CZ) NU20-04-00389
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : neurosteroids * schizophrenia * MK-801 * cognition * anxiety * stress
OECD category: Neurosciences (including psychophysiology; Organic chemistry (UOCHB-X)
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/7/1026
Permanent Link: http://hdl.handle.net/11104/0321516 - 7.0544568 - FGÚ 2022 RIV IE eng J - Journal Article
Valeš, Karel - Holubová, K.
Minireview: Animal model of schizophrenia from the perspective of behavioral pharmacology: Effect of treatment on cognitive functions.
Neuroscience Letters. Roč. 761, Sep 14 (2021), č. článku 136098. ISSN 0304-3940. E-ISSN 1872-7972
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA ČR(CZ) GA18-09296S
Institutional support: RVO:67985823
Keywords : schizophrenia * antipsychotics * cognition * Morris water maze * pre-pulse inhibition * MK-801
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.197, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.neulet.2021.136098
Permanent Link: http://hdl.handle.net/11104/0321416 - 8.0543350 - FGÚ 2022 RIV US eng J - Journal Article
Kaniaková, Martina - Korábečný, J. - Holubová, Kristína - Kletečková, Lenka - Chvojková, Markéta - Hakenová, K. - Prchal, L. - Novák, M. - Doležal, R. - Hepnarová, V. - Svobodová, B. - Kučera, T. - Lichnerová, Katarina - Krausová, B. - Horák, Martin - Valeš, Karel - Soukup, O.
7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo.
Biochemical Pharmacology. Roč. 186, Apr (2021), č. článku 114460. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:67985823
Keywords : behavioral experiment * electrophysiology * glutamate receptor * mutation * ion channel * acetylcholinesterase
OECD category: Pharmacology and pharmacy
Impact factor: 6.100, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.bcp.2021.114460
Permanent Link: http://hdl.handle.net/11104/0320571 - 9.0541890 - FGÚ 2022 RIV CH eng J - Journal Article
Chvojková, Markéta - Kubová, Hana - Valeš, Karel
Effects of Dizocilpine, Midazolam and Their Co-Application on the Trimethyltin (TMT)-Induced Rat Model of Cognitive Deficit.
Brain Sciences. Roč. 11, č. 3 (2021), č. článku 400. E-ISSN 2076-3425
R&D Projects: GA ČR(CZ) GA18-09296S; GA ČR(CZ) GA14-20613S; GA MZd(CZ) NU20-04-00389; GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:67985823
Keywords : cognitive function * trimethyltin * hippocampus * NMDA receptor * GABA A receptor * dementia * combination therapy * Alzheimer’s disease * neurodegeneration * neuroprotection
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.333, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3425/11/3/400
Permanent Link: http://hdl.handle.net/11104/0319385 - 10.0535840 - FGÚ 2021 RIV PL eng J - Journal Article
Mareš, Pavel - Kudová, Eva - Valeš, Karel - Kubová, Hana
Three neurosteroids as well as GABAergic drugs do not convert immediate postictal potentiation to depression in immature rats.
Pharmacological Reports. Roč. 72, č. 6 (2020), s. 1573-1578. ISSN 1734-1140. E-ISSN 2299-5684
R&D Projects: GA ČR(CZ) GA18-09296S
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : cortical afterdischarges * postical potentiation * immature rats * neurosteroids * gabaergic drugs
OECD category: Neurosciences (including psychophysiology; Neurosciences (including psychophysiology (UOCHB-X)
Impact factor: 3.027, year: 2020
Method of publishing: Limited access
https://doi.org/10.1007/s43440-020-00113-2
Permanent Link: http://hdl.handle.net/11104/0314522