Search results
- 1.0575880 - ÚMG 2024 RIV US eng J - Journal Article
Berková, Linda - Fazilaty, H. - Yang, Q. - Kubovčiak, Jan - Šťastná, Monika - Hrčkulák, Dušan - Vojtěchová, Martina - Dalessi, T. - Brügger, M. D. - Hausmann, G. - Liberali, P. - Kořínek, Vladimír - Basler, K. - Valenta, Tomáš
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members.
Embo Reports. Roč. 24, č. 9 (2023), č. článku e56454. ISSN 1469-221X. E-ISSN 1469-3178
R&D Projects: GA ČR GA21-26025S; GA MŠMT LX22NPO5102
Institutional support: RVO:68378050
Keywords : enterocytes * epithelial differentiation * intestinal mesenchymal cells * small intestine * Tgfβ / Bmp signalling
OECD category: Cell biology
Impact factor: 7.7, year: 2022
Method of publishing: Open access
https://www.embopress.org/doi/full/10.15252/embr.202256454
Permanent Link: https://hdl.handle.net/11104/0345587File Download Size Commentary Version Access CC BY License EMBO Reports - 2023 - Berkov - Terminal differentiation of villus tip enterocytes is governed by distinct Tgf superfamily.pdf 1 6.8 MB Publisher’s postprint open-access - 2.0561378 - ÚMG 2023 RIV CH eng J - Journal Article
Švec, Jiří - Šťastná, Monika - Janečková, Lucie - Hrčkulák, Dušan - Vojtěchová, Martina - Onhajzer, Jakub - Kříž, Vítězslav - Galušková, Kateřina - Šloncová, Eva - Kubovčiak, Jan - Pfeiferová, Lucie - Hrudka, J. - Matěj, R. - Waldauf, P. - Havluj, L. - Kolář, Michal - Kořínek, Vladimír
TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial-Mesenchymal Transition and Invasiveness.
Cancers (Basel). Roč. 14, č. 17 (2022), č. článku 4137. E-ISSN 2072-6694
R&D Projects: GA ČR(CZ) GA18-26324S; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF16_019/0000785
Institutional support: RVO:68378050
Keywords : apc * colorectal cancer * emt * expression profiling * organoids * tacstd2 * WNT/beta-catenin signaling
OECD category: Oncology
Impact factor: 5.2, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/cancers14174137
Permanent Link: https://hdl.handle.net/11104/0338612File Download Size Commentary Version Access cancers-14-04137.pdf 0 8.6 MB Publisher’s postprint open-access - 3.0544827 - ÚEM 2022 RIV CH eng J - Journal Article
Kriška, Ján - Janečková, Lucie - Kirdajová, Denisa - Honsa, Pavel - Knotek, Tomáš - Džamba, Dávid - Koleničová, Denisa - Butenko, Olena - Vojtěchová, Martina - Čapek, Martin - Kozmik, Zbyněk - Taketo, M.M. - Kořínek, Vladimír - Anděrová, Miroslava
Wnt/beta-Catenin Signaling Promotes Differentiation of Ischemia-Activated Adult Neural Stem/Progenitor Cells to Neuronal Precursors.
Frontiers in Neuroscience. Roč. 15, feb. (2021), č. článku 628983. E-ISSN 1662-453X
R&D Projects: GA ČR(CZ) GA21-24674S; GA ČR(CZ) GA19-02046S; GA ČR(CZ) GA19-03016S
Institutional support: RVO:68378041 ; RVO:68378050
Keywords : Wnt signaling * transgenic mouse * neural stem * progenitor cell
OECD category: Neurosciences (including psychophysiology; Neurosciences (including psychophysiology (UMG-J)
Impact factor: 5.152, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.bcp.2021.114460
Permanent Link: http://hdl.handle.net/11104/0321841 - 4.0508788 - ÚMG 2020 RIV GB eng J - Journal Article
Horázná, Monika - Janečková, Lucie - Švec, Jiří - Babošová, Oľga - Hrčkulák, Dušan - Vojtěchová, Martina - Galušková, Kateřina - Šloncová, Eva - Kolář, Michal - Strnad, Hynek - Kořínek, Vladimír
Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium.
Scientific Reports. Roč. 9, č. 1 (2019), č. článku 1629. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR GA15-25100S; GA MŠMT LO1419; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2015062; GA MŠMT LO1220; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : human colon * stem-cells * gene * expression * adenoma * growth * differentiation * adenocarcinoma * identification * transformation
OECD category: Cell biology
Impact factor: 3.998, year: 2019
Method of publishing: Open access
https://www.nature.com/articles/s41598-018-38310-y
Permanent Link: http://hdl.handle.net/11104/0305732File Download Size Commentary Version Access Scientific_Reports_M_Horazna_2019.pdf 4 7.3 MB Publisher’s postprint require - 5.0500434 - ÚMG 2019 RIV CH eng J - Journal Article
Hrčkulák, Dušan - Janečková, Lucie - Láníková, Lucie - Kříž, Vítězslav - Horázná, Monika - Babošová, Oľga - Vojtěchová, Martina - Galušková, Kateřina - Šloncová, Eva - Kořínek, Vladimír
Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.
Genes. Roč. 9, č. 9 (2018), č. článku 439. E-ISSN 2073-4425
R&D Projects: GA ČR GA15-25100S; GA MŠMT LO1419; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2015062
Institutional support: RVO:68378050
Keywords : colorectal cancer * conditional gene inactivation * epithelium * gut * organoids * tcf7l2 * tumorigenesis * Wnt signaling
OECD category: Biochemistry and molecular biology
Impact factor: 3.331, year: 2018
Permanent Link: http://hdl.handle.net/11104/0292514File Download Size Commentary Version Access Genes_D_Hrckulak_2018.pdf 1 2.9 MB Publisher’s postprint require - 6.0472044 - ÚMG 2017 RIV US eng J - Journal Article
Janečková, Lucie - Kolář, Michal - Švec, Jiří - Láníková, Lucie - Pospíchalová, Vendula - Baloghová, Nikol - Vojtěchová, Martina - Šloncová, Eva - Strnad, Hynek - Kořínek, Vladimír
HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy.
Translational Oncology. Roč. 9, č. 2 (2016), s. 99-107. ISSN 1944-7124. E-ISSN 1936-5233
R&D Projects: GA ČR GAP305/12/2347; GA MŠMT LO1419; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : direct target gene * cancer 1 hic1 * colorectal-cancer * breast-cancer * lung-cancer * tgf-beta * methylation * hypermethylation * subtypes * cells
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.025, year: 2016
Permanent Link: http://hdl.handle.net/11104/0269388 - 7.0457224 - ÚMG 2017 RIV US eng J - Journal Article
Janečková, Lucie - Fafílek, Bohumil - Krausová, Michaela - Horázná, Monika - Vojtěchová, Martina - Alberich-Jorda, Meritxell - Šloncová, Eva - Galušková, Kateřina - Sedláček, Radislav - Anděrová, Miroslava - Kořínek, Vladimír
Wnt signaling inhibition deprives small intestinal stem cells of clonogenic capacity.
Genesis. Roč. 54, č. 3 (2016), s. 101-114. ISSN 1526-954X. E-ISSN 1526-968X
R&D Projects: GA ČR(CZ) GA14-33952S; GA ČR(CZ) GAP303/12/0855; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT LO1220; GA MŠMT LK21307; GA MŠMT(CZ) LM2011032; GA MŠMT EE2.3.30.0027
Institutional support: RVO:68378050 ; RVO:68378041
Keywords : b-catenin * Cre/loxP * gene targeting * gut * Wnt pathway * TCF/LEF transcription factors
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.143, year: 2016
Permanent Link: http://hdl.handle.net/11104/0257650 - 8.0455295 - ÚMG 2016 RIV US eng J - Journal Article
Janečková, Lucie - Pospíchalová, Vendula - Fafílek, Bohumil - Vojtěchová, Martina - Turečková, Jolana - Dobeš, Jan - Dubuissez, M. - Leprince, D. - Baloghová, Nikol - Horázná, Monika - Hlavatá, Adéla - Stančíková, Jitka - Šloncová, Eva - Galušková, Kateřina - Strnad, Hynek - Kořínek, Vladimír
HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-kappa B Signaling and Promotes Tissue Damage-Associated Tumorigenesis.
Molecular Cancer Research. Roč. 13, č. 7 (2015), s. 1139-1148. ISSN 1541-7786. E-ISSN 1557-3125
R&D Projects: GA ČR GAP305/12/2347; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : hypermethylated in cancer 1 * intestinal epithelium * colorectal cancer
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.510, year: 2015
Permanent Link: http://hdl.handle.net/11104/0255958File Download Size Commentary Version Access Molecular_Cancer_Research_L_Janeckova_2015.pdf 2 1.9 MB Publisher’s postprint require - 9.0441052 - ÚMG 2015 RIV GB eng J - Journal Article
Stančíková, Jitka - Krausová, Michaela - Kolář, Michal - Fafílek, Bohumil - Švec, Jiří - Sedláček, Radislav - Neroldová, M. - Dobeš, Jan - Horázná, Monika - Janečková, Lucie - Vojtěchová, Martina - Oliverius, M. - Jirsa, M. - Kořínek, Vladimír
NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling.
Cellular Signalling. Roč. 27, č. 2 (2015), s. 245-256. ISSN 0898-6568. E-ISSN 1873-3913
R&D Projects: GA ČR GAP305/11/1780; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LM2011032
Institutional support: RVO:68378050
Keywords : Wnt signaling * NKD 1 * Intestine * Liver * Colorectal cancer * Hepatocellular carcinoma
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.191, year: 2015
Permanent Link: http://hdl.handle.net/11104/0244122 - 10.0435312 - ÚMG 2015 RIV US eng J - Journal Article
Tůmová, Lucie - Pombinho, António R. - Vojtěchová, Martina - Stančíková, Jitka - Gradl, D. - Krausová, Michaela - Šloncová, Eva - Horázná, Monika - Kříž, Vítězslav - Machoňová, Olga - Jindřich, Jindřich - Zdráhal, Z. - Bartůněk, Petr - Kořínek, Vladimír
Monensin Inhibits Canonical Wnt Signaling in Human Colorectal Cancer Cells and Suppresses Tumor Growth in Multiple Intestinal Neoplasia Mice.
Molecular Cancer Therapeutics. Roč. 13, č. 4 (2014), s. 812-822. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR GAP305/12/2347; GA MPO FR-TI4/802; GA MŠMT LM2011022; GA MŠMT LO1220
Institutional support: RVO:68378050
Keywords : bate-catenin * throughput screen * small molecule inhibitors
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.683, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239216File Download Size Commentary Version Access 0435312.pdf 8 2.1 MB Publisher’s postprint require 0435312.pdf 8 2.1 MB Publisher’s postprint require