Search results
- 1.0579087 - ÚMG 2024 RIV GB eng J - Journal Article
Mikešová, J. - Miliaieva, D. - Štenclová, P. - Kindermann, M. - Vučková, T. - Mádlíková, M. - Fábry, Milan - Veverka, V. - Schimer, J. - Krejčí, P. - Stehlík, S. - Cígler, P.
Nanodiamonds as traps for fibroblast growth factors: Parameters influencing the interaction.
Carbon. Roč. 195, Aug 15 (2022), s. 372-386. ISSN 0008-6223. E-ISSN 1873-3891
Research Infrastructure: CzechNanoLab - 90110
Institutional support: RVO:68378050
Keywords : surface-chemistry * detonation nanodiamonds * fourier-transform * size * nanoparticles * fluorescence * temperature * adsorption * reactivity * proteins * Nanodiamond * Fibroblast growth factor * Binding * Sequestration * Thermodynamics
OECD category: Biochemistry and molecular biology
Impact factor: 10.9, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0008622322002871?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0347956 - 2.0552098 - ÚMG 2022 RIV CH eng J - Journal Article
Kalousková, B. - Skořepa, O. - Cmunt, D. - Abreu, C. - Krejčová, K. - Blaha, J. - Sieglová, Irena - Král, Vlastimil - Fábry, Milan - Pola, Robert - Pechar, Michal - Vaněk, O.
Tumor Marker B7-H6 Bound to the Coiled Coil Peptide-Polymer Conjugate Enables Targeted Therapy by Activating Human Natural Killer Cells.
Biomedicines. Roč. 9, č. 11 (2021), č. článku 1597. E-ISSN 2227-9059
R&D Projects: GA ČR(CZ) GA18-10687S; GA ČR(CZ) GA21-11688S; GA MŠMT(CZ) LM2018127
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:68378050 ; RVO:61389013
Keywords : coiled coil * HPMA polymer * NK cell * NKp30 * b7-h6 * immunotherapy
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 4.757, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2227-9059/9/11/1597
Permanent Link: http://hdl.handle.net/11104/0327244 - 3.0548921 - ÚOCHB 2022 RIV US eng J - Journal Article
Čermáková, Kateřina - Demeulemeester, J. - Lux, Vanda - Nedomová, Monika - Goldman, S. R. - Smith, E. A. - Srb, Pavel - Hexnerová, Rozálie - Fábry, Milan - Mádlíková, Marcela - Hořejší, Magdalena - Rijck, J. D. - Debyser, Z. - Adelman, K. - Hodges, H. C. - Veverka, Václav
A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science. Roč. 374, č. 6571 (2021), s. 1113-1121. ISSN 0036-8075. E-ISSN 1095-9203
R&D Projects: GA ČR(CZ) GA19-14360S; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : mediator subunit med26 * N-terminal domain * structural characterization
OECD category: Biochemistry and molecular biology
Impact factor: 63.832, year: 2021
Method of publishing: Limited access
https://doi.org/10.1126/science.abe2913
Permanent Link: http://hdl.handle.net/11104/0324967 - 4.0548554 - ÚMG 2022 RIV DE eng J - Journal Article
Kugler, Michael - Nekvinda, J. - Holub, J. - El Anwar, S. - Das, V. - Šícha, V. - Pospíšilová, K. - Fábry, Milan - Král, Vlastimil - Brynda, Jiří - Kašička, V. - Hajduch, M. - Řezáčová, Pavlína - Grüner, B.
Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds.
Chembiochem. Roč. 22, č. 18 (2021), s. 2741-2761. ISSN 1439-4227. E-ISSN 1439-7633
Institutional support: RVO:68378050
Keywords : carbonic anhydrase * carborane * cobalt bis(dicarbollide) * crystallography * enzyme inhibition * SAR studies
OECD category: Biochemistry and molecular biology
Impact factor: 3.468, year: 2021
Method of publishing: Limited access
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202100121
Permanent Link: http://hdl.handle.net/11104/0324600 - 5.0548549 - ÚMG 2022 RIV GB eng J - Journal Article
Šoltysová, M. - Sieglová, Irena - Fábry, Milan - Brynda, Jiří - Škerlová, Jana - Řezáčová, Pavlína
Structural insight into DNA recognition by bacterial transcriptional regulators of the SorC/DeoR family.
Acta Crystallographica Section D-Structural Biology. Roč. 77, č. 11 (2021), s. 1411-1424. ISSN 2059-7983. E-ISSN 2059-7983
Institutional support: RVO:68378050
Keywords : SorC/DeoR family * protein-DNA complexes * transcription repressors * Bacillus subtilis * deoxyribonucleoside regulator bsDeoR * gene regulator bsCggR * carbohydrate catabolism
OECD category: Biochemistry and molecular biology
Impact factor: 5.699, year: 2021
Method of publishing: Limited access
https://scripts.iucr.org/cgi-bin/paper?S2059798321009633
Permanent Link: http://hdl.handle.net/11104/0324596 - 6.0544836 - ÚMG 2022 RIV GB eng J - Journal Article
Vuorio, J. - Škerlová, Jana - Fábry, Milan - Veverka, V. - Vattulainen, I. - Řezáčová, Pavlína - Martinez-Seara, H.
N-Glycosylation can selectively block or foster different receptor-ligand binding modes.
Scientific Reports. Roč. 11, č. 1 (2021), č. článku 5239. ISSN 2045-2322. E-ISSN 2045-2322
Institutional support: RVO:68378050
Keywords : N-glycosylation * simulations and NMR * importance of glycosylation in protein function
OECD category: Cell biology
Impact factor: 4.997, year: 2021
Method of publishing: Open access
https://www.nature.com/articles/s41598-021-84569-z
Permanent Link: http://hdl.handle.net/11104/0321647 - 7.0539172 - ÚMG 2021 RIV GB eng J - Journal Article
Lux, V. - Brouns, T. - Cermakova, K. - Srb, P. - Fábry, Milan - Mádlíková, M. - Hořejší, Magdalena - Kukačka, Z. - Novák, P. - Kugler, M. - Brynda, Jiří - DeRijck, J. - Christ, F. - Debyser, Z. - Veverka, V.
Molecular Mechanism of LEDGF/p75 Dimerization.
Structure. Roč. 28, č. 12 (2020), s. 1288-1299. ISSN 0969-2126. E-ISSN 1878-4186
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : PSIP1 * domain swapping * eletrostatic stapling * epigenetics * mixed-lineage leukemia * paramagnetic NMR * protein-protein interaction * transcription
OECD category: Biochemistry and molecular biology
Impact factor: 5.006, year: 2020
Method of publishing: Limited access
https://www.cell.com/structure/fulltext/S0969-2126(20)30325-7?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0969212620303257%3Fshowall%3Dtrue
Permanent Link: http://hdl.handle.net/11104/0316873 - 8.0539170 - ÚMG 2021 RIV GB eng J - Journal Article
Kugler, Michael - Holub, J. - Brynda, Jiří - Pospíšilová, K. - El Anwar, S. - Bavol, D. - Havránek, M. - Král, Vlastimil - Fábry, Milan - Gruner, B. - Řezáčová, Pavlína
The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 35, č. 1 (2020), s. 1800-1810. ISSN 1475-6366. E-ISSN 1475-6374
Institutional support: RVO:68378050
Keywords : tumor hypoxia * medicinal chemistry * drug discovery * binding-sites * inhibition * boron * pharmacophores * opportunities * conjugation * metastasis * Carbonic anhydrase IX * carborane * enzyme inhibitors * structure-activity relationship
OECD category: Biochemistry and molecular biology
Impact factor: 5.051, year: 2020
Method of publishing: Open access
https://www.tandfonline.com/doi/full/10.1080/14756366.2020.1816996
Permanent Link: http://hdl.handle.net/11104/0316870 - 9.0532248 - ÚACH 2022 RIV DE eng J - Journal Article
Grüner, Bohumír - Kugler, Michael - El Anwar, Suzan - Holub, Josef - Nekvinda, Jan - Bavol, Dmytro - Růžičková, Z. - Pospíšilová, K. - Fábry, Milan - Král, Vlastimil - Brynda, Jiří - Řezáčová, P.
Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX.
ChemPlusChem. Roč. 86, č. 3 (2021), s. 352-363. ISSN 2192-6506. E-ISSN 2192-6506
R&D Projects: GA ČR(CZ) GA18-27648S
Grant - others:AV ČR(CZ) L200321851
Program: Program podpory perspektivníchlidských zdrojů - postdoktorandů
Institutional support: RVO:61388980 ; RVO:68378050
Keywords : anti-tumor agents * carbonic anhydrase IX * carboranes * cobalt Bis(dicarbollide) * enzyme inhibitors
OECD category: Inorganic and nuclear chemistry; Human genetics (UMG-J)
Impact factor: 3.210, year: 2021
Method of publishing: Open access with time embargo
Permanent Link: http://hdl.handle.net/11104/0318394File Download Size Commentary Version Access Cobalt.pdf 0 1.9 MB Author’s postprint open-access Cobalt SI.pdf 0 5.5 MB Author’s postprint open-access - 10.0531266 - ÚMG 2021 RIV FR eng J - Journal Article
Dvořanová, J. - Kugler, Michael - Holub, J. - Šícha, V. - Das, V. - Nekvinda, J. - El Anwar, S. - Havránek, M. - Pospíšilová, K. - Fábry, Milan - Král, Vlastimil - Medvědiková, M. - Matějková, S. - Lišková, B. - Gurská, S. - Dzubak, P. - Brynda, Jiří - Hajduch, M. - Gruner, B. - Řezáčová, P.
Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
European Journal of Medicinal Chemistry. Roč. 200, August (2020), č. článku 112460. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA15-05677S
Institutional support: RVO:68378050
Keywords : Anti-tumor agents * Carbonic anhydrase IX * Carboranes * Dicarbollide * Enzyme inhibitors * Drug penetration * Multicellular spheroids
OECD category: Medicinal chemistry
Impact factor: 6.514, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0223523420304311?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0309958