Search results

  1. 1.
    0565337 - ÚMCH 2024 RIV NL eng J - Journal Article
    Kostka, Libor - Kotrchová, Lenka - Randárová, Eva - Ferreira, C. A. - Malátová, Iva - Lee, H. J. - Olson, A. P. - Engle, J. W. - Kovář, Marek - Cai, W. - Šírová, Milada - Etrych, Tomáš
    Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models.
    Journal of Controlled Release. Roč. 353, January (2023), s. 549-562. ISSN 0168-3659. E-ISSN 1873-4995
    R&D Projects: GA MŠk LX22NPO5102; GA MŠk(CZ) LTAUSA18083
    Grant - others:AV ČR(CZ) MSM200502104
    Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
    Institutional support: RVO:61389013 ; RVO:61388971
    Keywords : drug delivery * cancer * polymeric carriers
    OECD category: Polymer science; Pharmacology and pharmacy (MBU-M)
    Impact factor: 10.8, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0168365922008148?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0336896
    FileDownloadSizeCommentaryVersionAccess
    0565337.pdf08 MBCreative Commons Attribution 4.0 International License (CC BY)Publisher’s postprintopen-access
     
     
  2. 2.
    0563741 - MBÚ 2023 RIV CH eng J - Journal Article
    Antošová, Z. - Podzimkova, N. - Tomala, Jakub - Augustýnková, K. - Sajnerová, K. - Nedvědová, E. - Šírová, Milada - de Martynoff, G. - Bechard, D. - Moebius, U. - Kovář, Marek - Špíšek, R. - Adkins, I.
    SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity.
    Frontiers in Immunology. Roč. 13, OCT 10 2022 (2022), č. článku 989895. ISSN 1664-3224. E-ISSN 1664-3224
    Institutional support: RVO:61388971
    Keywords : NK cells * antibody-dependent cytotoxicity * interleukin-15 * immunotherapy * therapeutic antibodies * rli-15
    OECD category: Oncology
    Impact factor: 7.3, year: 2022
    Method of publishing: Open access
    https://www.frontiersin.org/articles/10.3389/fimmu.2022.989895/full
    Permanent Link: https://hdl.handle.net/11104/0335572
     
     
  3. 3.
    0559474 - ÚMCH 2023 RIV US eng J - Journal Article
    Kousalová, Jana - Šírová, Milada - Kostka, Libor - Šubr, Vladimír - Kovářová, Jiřina - Běhalová, Kateřina - Studenovský, Martin - Kovář, Marek - Etrych, Tomáš
    Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines.
    Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 44, August (2022), č. článku 102578. ISSN 1549-9634. E-ISSN 1549-9642
    R&D Projects: GA MŠk(CZ) LTAUSA18083
    Grant - others:AV ČR(CZ) JSPS-22-01
    Program: Bilaterální spolupráce
    Institutional support: RVO:61389013 ; RVO:61388971
    Keywords : matrix metalloproteinases * metastases * actinonin
    OECD category: Polymer science; Oncology (MBU-M)
    Impact factor: 5.4, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S1549963422000648?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0332758
     
     
  4. 4.
    0558142 - ÚMCH 2023 RIV US eng J - Journal Article
    Kostka, Libor - Sivák, Ladislav - Šubr, Vladimír - Kovářová, Jiřina - Šírová, Milada - Říhová, Blanka - Sedláček, Radislav - Etrych, Tomáš - Kovář, Marek
    Simultaneous delivery of doxorubicin and protease inhibitor derivative to solid tumors via star-shaped polymer nanomedicines overcomes P-gp- and STAT3-mediated chemoresistance.
    Biomacromolecules. Roč. 23, č. 6 (2022), s. 2522-2535. ISSN 1525-7797. E-ISSN 1526-4602
    R&D Projects: GA ČR(CZ) GA19-05649S; GA MZd(CZ) NU21-03-00273; GA MŠk(CZ) LTAUSA18083; GA MŠk(CZ) LM2018126; GA MŠk(CZ) ED1.1.00/02.0109
    Research Infrastructure: CCP II - 90126
    Institutional support: RVO:61389013 ; RVO:61388971 ; RVO:68378050
    Keywords : HPMA * RAFT * star-like
    OECD category: Polymer science; Microbiology (MBU-M); Genetics and heredity (medical genetics to be 3) (UMG-J)
    Impact factor: 6.2, year: 2022
    Method of publishing: Limited access
    https://pubs.acs.org/doi/10.1021/acs.biomac.2c00256
    Permanent Link: https://hdl.handle.net/11104/0332796
     
     
  5. 5.
    0556381 - MBÚ 2023 RIV US eng J - Journal Article
    Vrbata, David - Filipová, Marcela - Tavares, Marina Rodrigues - Červený, Jakub - Vlachová, Miluše - Šírová, Milada - Pelantová, Helena - Petrásková, Lucie - Bumba, Ladislav - Konefal, Rafal - Etrych, Tomáš - Křen, Vladimír - Chytil, Petr - Bojarová, Pavla
    Glycopolymers Decorated with 3-O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3.
    Journal of Medicinal Chemistry. Roč. 65, č. 5 (2022), s. 3866-3878. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA MŠk(CZ) LTC19038; GA ČR(CZ) GA22-00262S; GA MZd(CZ) NU21-03-00273
    EU Projects: European Commission(XE) CA17140 - COST Action
    Institutional support: RVO:61388971 ; RVO:61389013
    Keywords : digit nm affinity * high selectivity * click chemistry * copolymers * glycopeptide * recognition * derivatives * apoptosis * fibrosis * arginine
    OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
    Impact factor: 7.3, year: 2022
    Method of publishing: Limited access
    https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01625
    Permanent Link: http://hdl.handle.net/11104/0330739
     
     
  6. 6.
    0542896 - MBÚ 2022 RIV NL eng J - Journal Article
    Sivák, Ladislav - Šubr, Vladimír - Kovářová, Jiřina - Dvořáková, Barbora - Šírová, Milada - Říhová, Blanka - Randárová, Eva - Kraus, Michal - Tomala, Jakub - Studenovský, Martin - Vondráčková, Michaela - Sedláček, Radislav - Makovický, Peter - Fučíková, J. - Vošahlíková, Š. - Spíšek, R. - Kostka, Libor - Etrych, Tomáš - Kovář, Marek
    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.
    Journal of Controlled Release. Roč. 332, APR 10 2021 (2021), s. 563-580. ISSN 0168-3659. E-ISSN 1873-4995
    R&D Projects: GA ČR(CZ) GA19-05649S; GA MŠk(CZ) LM2015040; GA MŠk(CZ) ED1.1.00/02.0109
    Research Infrastructure: CCP - 90040
    Institutional support: RVO:61388971 ; RVO:61389013 ; RVO:68378050
    Keywords : Ritonavir derivate * Polymer carrier * pH-controlled release * Antitumor activity * Proteasome inhibition * STAT3 signaling inhibition
    OECD category: Microbiology; Polymer science (UMCH-V)
    Impact factor: 11.467, year: 2021
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0168365921001267
    Permanent Link: http://hdl.handle.net/11104/0320232
     
     
  7. 7.
    0539979 - ÚMCH 2022 RIV CH eng J - Journal Article
    Tavares, Marina Rodrigues - Hrabánková, Klára - Konefal, Rafal - Kaňa, Martin - Říhová, Blanka - Etrych, Tomáš - Šírová, Milada - Chytil, Petr
    HPMA-based copolymers carrying STAT3 inhibitor cucurbitacin-D as stimulus-sensitive nanomedicines for oncotherapy.
    Pharmaceutics. Roč. 13, č. 2 (2021), č. článku 179. E-ISSN 1999-4923
    R&D Projects: GA ČR(CZ) GA17-08084S; GA MŠk(CZ) LTAUSA18083
    Institutional support: RVO:61389013 ; RVO:61388971
    Keywords : cucurbitacin-D * immuno-oncotherapy * N-(2-hydroxypropyl) methacrylamide (HPMA)
    OECD category: Polymer science; Microbiology (MBU-M)
    Impact factor: 6.525, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/1999-4923/13/2/179
    Permanent Link: http://hdl.handle.net/11104/0317666
     
     
  8. 8.
    0522842 - ÚMCH 2021 RIV NL eng J - Journal Article
    Braunová, Alena - Chytil, Petr - Laga, Richard - Šírová, Milada - Machová, Daniela - Parnica, Jozef - Říhová, Blanka - Janoušková, Olga - Etrych, Tomáš
    Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties.
    Journal of Controlled Release. Roč. 321, 10 May (2020), s. 718-733. ISSN 0168-3659. E-ISSN 1873-4995
    R&D Projects: GA MZd(CZ) NV16-28600A; GA ČR(CZ) GA17-13283S; GA ČR(CZ) GA17-08084S; GA MŠk(CZ) LQ1604; GA MŠk(CZ) LTAUSA18083; GA MŠk(CZ) ED1.1.00/02.0109; GA ČR(CZ) GA19-01417S
    Institutional support: RVO:61389013 ; RVO:61388971
    Keywords : polymer micelles * drug delivery * EPR effect
    OECD category: Polymer science; Microbiology (MBU-M)
    Impact factor: 9.776, year: 2020
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0168365920301413?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0308163
     
     
  9. 9.
    0521948 - ÚMCH 2021 RIV GB eng J - Journal Article
    Kostka, Libor - Kotrchová, Lenka - Šubr, Vladimír - Libánská, Alena - Ferreira, C. A. - Malátová, Iva - Lee, H. J. - Barnhart, T. E. - Engle, J. W. - Cai, W. - Šírová, Milada - Etrych, Tomáš
    HPMA-based star polymer biomaterials with tuneable structure and biodegradability tailored for advanced drug delivery to solid tumours.
    Biomaterials. Roč. 235, March (2020), s. 1-14, č. článku 119728. ISSN 0142-9612. E-ISSN 1878-5905
    R&D Projects: GA MŠk(CZ) LTAUSA18083; GA MŠk(CZ) LQ1604; GA MŠk(CZ) ED1.1.00/02.0109; GA ČR(CZ) GA17-13283S; GA ČR(CZ) GA19-05649S; GA MZd(CZ) NV16-28600A
    Institutional support: RVO:61389013 ; RVO:61388971
    Keywords : HPMA * star-like polymers * drug delivery
    OECD category: Polymer science; Microbiology (MBU-M)
    Impact factor: 12.479, year: 2020
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0142961219308464?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0306712
     
     
  10. 10.
    0510951 - ÚMCH 2020 RIV CH eng J - Journal Article
    Braunová, Alena - Kaňa, Martin - Kudláčová, Júlia - Kostka, Libor - Bouček, J. - Betka, J. - Šírová, Milada - Etrych, Tomáš
    Micelle-forming block copolymers tailored for inhibition of P-gp-mediated multidrug resistance: structure to activity relationship.
    Pharmaceutics. Roč. 11, č. 11 (2019), s. 1-22, č. článku 579. E-ISSN 1999-4923
    R&D Projects: GA MZd(CZ) NV16-28600A
    Institutional support: RVO:61389013 ; RVO:61388971
    Keywords : polymer therapeutics * multidrug resistance * micelles
    OECD category: Polymer science; Microbiology (MBU-M)
    Impact factor: 4.421, year: 2019
    Method of publishing: Open access
    https://www.mdpi.com/1999-4923/11/11/579/pdf
    Permanent Link: http://hdl.handle.net/11104/0304086
     
     

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