Search results
- 1.0636154 - MBÚ 2026 RIV NL eng J - Journal Article
Růžičková, Eliška - Zhuk, Karyna - Navarrete, Kevin Munoz - Osičková, Adriana - Osička, Radim
Kingella kingae cytotoxin RtxA induces an innate immune response in oral epithelial cells.
Current Research in Microbial Sciences. Roč. 8, April 2025 (2025), č. článku 100393. ISSN 2666-5174
R&D Projects: GA ČR(CZ) GA22-15825S; GA MŠMT(CZ) LM2023053
Institutional support: RVO:61388971
Keywords : escherichia-coli * septic arthritis * alpha-hemolysin * emerging pathogen * gene-expression * sp nov. * children * toxin * infections * henriksen * Innate immunity * Kingella kingae * Oral epithelial cells * Repeats-in-toxin * RtxA
OECD category: Microbiology
Impact factor: 4.8, year: 2023
Method of publishing: Open access
Result website:
https://www.webofscience.com/wos/woscc/full-record/WOS:001481278700001DOI: https://doi.org/10.1016/j.crmicr.2025.100393
Permanent Link: https://hdl.handle.net/11104/0367165 - 2.0619463 - MBÚ 2026 RIV US eng J - Journal Article
Espinosa-Vinals, Carlos Angel - Holubová, Jana - Staněk, Ondřej - Osička, Radim - Mašín, Jiří - Arellano Herencia, Fresia Esther - Šebo, Peter
Intranasal application of a bifunctional pertactin-RTX fusion antigen elicits protection of mouse airway mucosa against Bordetella pertussis colonization.
mSphere. Roč. 10, č. 4 (2025), č. článku 00959-24. ISSN 2379-5042. E-ISSN 2379-5042
R&D Projects: GA MŠMT(CZ) LM2023053; GA ČR(CZ) GX19-27630X; GA ČR(CZ) GA22-01558S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EH22_008/0004597
Research Infrastructure: CIISB II - 90127; CIISB III - 90242
Institutional support: RVO:61388971
Keywords : adenylate-cyclase toxin * folding mechanism * p.69 pertactin * secretion * protein * inhibition * antibodies * vaccines * immunity * identification * italicBordetella pertussis</italic> * adenylate cyclase toxin * pertactin * whooping cough * pertussis * protein folding * protection
OECD category: Microbiology
Impact factor: 3.7, year: 2023 ; AIS: 1.205, rok: 2023
Method of publishing: Open access
Result website:
https://journals.asm.org/doi/10.1128/msphere.00959-24DOI: https://doi.org/10.1128/msphere.00959-24
Permanent Link: https://hdl.handle.net/11104/0366246File Download Size Commentary Version Access espinosa-vinals-et-al-intranasal-application-of-a-bifunctional-pertactin-rtx-fusion-antigen-elicits-protection-of-mouse (1).pdf 2 7.4 MB Publisher’s postprint open-access - 3.0619024 - MBÚ 2026 RIV NL eng J - Journal Article
Khaliq, Humaira - Osičková, Adriana - Lichvárová, Michaela - Šulc, M. - Navarrete, Kevin Munoz - Espinosa-Vinals, Carlos Angel - Mašín, Jiří - Osička, Radim
Structural and functional significance of two conserved lysine residues in acylated sites of Kingella kingae RtxA cytotoxin.
Biochimie. Roč. 232, May 2025 (2025), s. 105-116. ISSN 0300-9084. E-ISSN 1638-6183
R&D Projects: GA ČR(CZ) GA22-15825S; GA MŠMT(CZ) LM2023053; GA MŠMT(CZ) EH22_008/0004597
Institutional support: RVO:61388971
Keywords : Acylation * Bacterial two-hybrid system * Kingella kingae * Planar lipid membranes * Pore-forming toxin * RtxA
OECD category: Biochemistry and molecular biology
Impact factor: 3.3, year: 2023 ; AIS: 0.726, rok: 2023
Method of publishing: Open access
Result website:
https://www.sciencedirect.com/science/article/pii/S0300908424003201DOI: https://doi.org/10.1016/j.biochi.2024.12.016
Permanent Link: https://hdl.handle.net/11104/0365790File Download Size Commentary Version Access 2025 Khaliq.pdf 0 2.6 MB Publisher’s postprint open-access Research data: data1 - 4.0601838 - MBÚ 2025 RIV NL eng J - Journal Article
Růžičková, Eliška - Lichvárová, Michaela - Osičková, Adriana - Filipi, Kateřina - Jurnečka, David - Khaliq, Humaira - Espinosa-Vinals, Carlos Angel - Pompach, Petr - Mašín, Jiří - Osička, Radim
Two pairs of back-to-back alpha-helices of Kingella kingae RtxA toxin are crucial for the formation of a membrane pore.
International Journal of Biological Macromolecules. Roč. 283, December 21 (2024), č. článku 137604. ISSN 0141-8130. E-ISSN 1879-0003
R&D Projects: GA ČR(CZ) GA22-15825S; GA MŠMT(CZ) LM2023053; GA MŠMT(CZ) EF18_046/0015974; GA MŠMT(CZ) EH22_008/0004597; GA MŠMT LM2023042
Research Infrastructure: CIISB III - 90242
Institutional support: RVO:61388971 ; RVO:86652036
Keywords : Kingella kingae * Membrane topology * RtxA * Structure-function
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (BTO-N)
Impact factor: 7.7, year: 2023 ; AIS: 0.969, rok: 2023
Method of publishing: Open access
Result website:
https://www.sciencedirect.com/science/article/pii/S0141813024084149?via%3DihubDOI: https://doi.org/10.1016/j.ijbiomac.2024.137604
Permanent Link: https://hdl.handle.net/11104/0359096File Download Size Commentary Version Access 2024 Ruzickova_Two pairs.pdf 2 8.5 MB Publisher’s postprint open-access - 5.0599431 - BTÚ 2025 RIV GB eng J - Journal Article
Kuchař, Milan - Sloupenská, K. - Kafkova, L. R. - Groza, Yaroslava - Škarda, J. - Kosztyu, P. - Hlavničková, Marie - Mierzwicka, Joanna Maria - Osička, Radim - Petroková, Hana - Walimbwa, S. I. - Bharadwaj, Shiv - Černý, Jiří - Raška, M. - Malý, Petr
Human IL-22 receptor-targeted small protein antagonist suppress murine DSS-induced colitis.
Cell communication and signaling : CCS. Roč. 22, č. 1 (2024), č. článku 469. ISSN 1478-811X. E-ISSN 1478-811X
R&D Projects: GA ČR(CZ) GF21-16423K
Institutional support: RVO:86652036 ; RVO:61388971
Keywords : albumin-binding domain * intestinal inflammation * soluble receptor * interleukin-22 * cells * innate * cytokine * immunity
OECD category: Cell biology
Impact factor: 8.2, year: 2023 ; AIS: 1.811, rok: 2023
Method of publishing: Open access
Result website:
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-024-01846-wDOI: https://doi.org/10.1186/s12964-024-01846-w
Permanent Link: https://hdl.handle.net/11104/0357623File Download Size Commentary Version Access Human IL-22 receptor-targeted small protein antagonist suppress murine DSS-induced colitis.pdf 1 8.7 MB Author´s preprint open-access - 6.0586070 - BTÚ 2025 RIV GB eng J - Journal Article
Groza, Yaroslava - Lacina, L. - Kuchař, Milan - Kafkova, L. R. - Zachová, K. - Janousková, O. - Osička, Radim - Černý, Jiří - Petroková, Hana - Mierzwicka, Joanna Maria - Panova, Natalya - Kosztyu, P. - Sloupenská, K. - Malý, J. - Škarda, J. - Raška, M. - Smetana Jr, K. - Malý, Petr
Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells.
Cell communication and signaling : CCS. Roč. 22, č. 1 (2024), č. článku 261. ISSN 1478-811X. E-ISSN 1478-811X
R&D Projects: GA ČR(CZ) GF21-16423K; GA MŠMT(CZ) EF16_025/0007397; GA MŠMT(CZ) LM2023053
Institutional support: RVO:86652036 ; RVO:61388971
Keywords : albumin-binding domain * stat3 * phosphorylation * interleukin-6 * resistance * Protein engineering
OECD category: Cell biology
Impact factor: 8.2, year: 2023 ; AIS: 1.811, rok: 2023
Method of publishing: Open access
Result website:
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-024-01630-wDOI: https://doi.org/10.1186/s12964-024-01630-w
Permanent Link: https://hdl.handle.net/11104/0355684File Download Size Commentary Version Access Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells..pdf 1 16.7 MB Author´s preprint open-access - 7.0585467 - MBÚ 2025 RIV NL eng J - Journal Article
Lepesheva, Anna - Grobarčíková, Michaela - Osičková, Adriana - Jurnečka, David - Knoblochová, Šárka - Čížková, Monika - Osička, Radim - Šebo, Peter - Mašín, Jiří
Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.
Biochimica Et Biophysica Acta-Biomembranes. Roč. 1866, č. 5 (2024), s. 184311. ISSN 0005-2736. E-ISSN 1879-2642
R&D Projects: GA ČR(CZ) GA22-15825S; GA ČR(CZ) GA22-01558S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EH22_008/0004597
Research Infrastructure: EATRIS-CZ IV - 90253; CIISB III - 90242
Institutional support: RVO:61388971
Keywords : RTX toxin * Adenylate cyclase toxin * α-Hemolysin * Chimera * Fatty acylation * Cytotoxicity
OECD category: Microbiology
Impact factor: 2.8, year: 2023 ; AIS: 0.771, rok: 2023
Method of publishing: Open access
Result website:
https://www.sciencedirect.com/science/article/pii/S0005273624000427?via%3DihubDOI: https://doi.org/10.1016/j.bbamem.2024.184311
Permanent Link: https://hdl.handle.net/11104/0353157File Download Size Commentary Version Access Modification of the RTX.pdf 17 3 MB Publisher’s postprint open-access - 8.0579872 - ÚMG 2024 RIV GB eng J - Journal Article
Gruper, Y. - Wolff, A. S. B. - Glanz, L. - Špoutil, František - Marthinussen, M. C. - Osičková, Adriana - Herzig, Y. - Goldfarb, Y. - Aranaz-Novaliches, Gorreti - Dobeš, J. - Kadouri, N. - Ben-Nun, O. - Binyamin, A. - Lavi, B. - Givony, T. - Khalaila, R. - Gome, T. - Wald, Tomáš - Mrázková, Blanka - Sochen, C. - Besnard, M. - Ben-Dor, S. - Feldmesser, E. - Orlova, E. M. - Hegedus, C. - Lampe, I. - Papp, T. - Felszeghy, S. - Sedláček, Radislav - Davidovich, E. - Tal, N. - Shouval, D. S. - Shamir, R. - Guillonneau, C. - Szondy, Z. - Lundin, K. E. A. - Osička, Radim - Procházka, Jan - Husebye, E. S. - Abramson, J.
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease.
Nature. Roč. 624, č. 7992 (2023), s. 653-662. ISSN 0028-0836. E-ISSN 1476-4687
R&D Projects: GA MŠMT(CZ) LM2023053; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA ČR GJ19-19025Y; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
Research Infrastructure: Czech-BioImaging II - 90129
Institutional support: RVO:68378050 ; RVO:61388971
Keywords : antibody * enamel * immune response * protein * tolerance * tooth
OECD category: Biochemistry and molecular biology; Immunology (MBU-M)
Impact factor: 50.5, year: 2023 ; AIS: 24.765, rok: 2023
Method of publishing: Limited access
Result website:
https://www.nature.com/articles/s41586-023-06776-0DOI: https://doi.org/10.1038/s41586-023-06776-0
Permanent Link: https://hdl.handle.net/11104/0348991 - 9.0578936 - MBÚ 2024 RIV US eng J - Journal Article
Wu, Y. - Du, S. - Bimler, Lynn H. - Mauk, K. E. - Lortal, L. - Kichik, N. - Griffiths, J. S. - Osička, Radim - Song, L. - Polsky, K. - Kasper, L. - Šebo, Peter - Weatherhead, J. - Knight, J. M. - Kheradmand, F. - Zheng, H. - Richardson, J. P. - Hube, B. - Naglik, J. R. - Corry, D. B.
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis.
Cell Reports. Roč. 42, č. 10 (2023), č. článku 113240. ISSN 2211-1247. E-ISSN 2211-1247
R&D Projects: GA MŠMT(CZ) LM2023053
Institutional support: RVO:61388971
Keywords : secreted aspartic proteinases * central-nervous-system * allergic responses * fungal-infection * brain * tissue * identification * recognition * astrocytes * generation
OECD category: Microbiology
Impact factor: 7.5, year: 2023 ; AIS: 3.781, rok: 2023
Method of publishing: Open access
Result website:
https://www.sciencedirect.com/science/article/pii/S2211124723012524?via%3DihubDOI: https://doi.org/10.1016/j.celrep.2023.113240
Permanent Link: https://hdl.handle.net/11104/0347845 - 10.0575316 - MBÚ 2024 RIV NL eng J - Journal Article
Rahman, Waheed Ur - Fišer, Radovan - Osička, Radim
Kingella kingae RtxA toxin interacts with sialylated gangliosides.
Microbial Pathogenesis. Roč. 181, AUG (2023), č. článku 106200. ISSN 0882-4010. E-ISSN 1096-1208
R&D Projects: GA ČR(CZ) GA22-15825S; GA MŠMT(CZ) LM2023053
Institutional support: RVO:61388971
Keywords : Gangliosides * Kingella kingae * RtxA * RTX toxins * Sialic acid * Vesicles
OECD category: Microbiology
Impact factor: 3.3, year: 2023 ; AIS: 0.621, rok: 2023
Method of publishing: Limited access
Result website:
https://www.sciencedirect.com/science/article/pii/S0882401023002334?via%3DihubDOI: https://doi.org/10.1016/j.micpath.2023.106200
Permanent Link: https://hdl.handle.net/11104/0345099