Search results

  1. 1.
    0556379 - MBÚ 2023 RIV CH eng J - Journal Article
    Filipi, Kateřina - Rahman, Waheed Ur - Osičková, Adriana - Osička, Radim
    Kingella kingae RtxA Cytotoxin in the Context of Other RTX Toxins.
    Microorganisms. Roč. 10, č. 3 (2022), č. článku 518. E-ISSN 2076-2607
    Institutional support: RVO:61388971
    Keywords : escherichia-coli-hemolysin * adenylate-cyclase toxin * aggregatibacter-actinomycetemcomitans leukotoxin * pasteurella-haemolytica leukotoxin * real-time pcr * polymerase-chain-reaction * outer-membrane vesicles * bordetella-pertussis cyaa * terminal secretion signal * cell-invasive activity * beta(2) integrins * Kingella kingae * membrane * pore-forming * RtxA * RTX toxin
    OECD category: Microbiology
    Impact factor: 4.128, year: 2020
    Method of publishing: Open access
    https://www.mdpi.com/2076-2607/10/3/518
    Permanent Link: http://hdl.handle.net/11104/0331349
     
     
  2. 2.
    0549727 - MBÚ 2022 RIV CH eng J - Journal Article
    Holubová, Jana - Juhasz, Attila - Mašín, Jiří - Staněk, Ondřej - Jurnečka, David - Osičková, Adriana - Šebo, Peter - Osička, Radim
    Selective enhancement of the cell-permeabilizing activity of adenylate cyclase toxin does not increase virulence of bordetella pertussis.
    International Journal of Molecular Sciences. Roč. 22, č. 21 (2021), č. článku 11655. E-ISSN 1422-0067
    R&D Projects: GA MŠk(CZ) LM2018133; GA ČR(CZ) GA19-12695S
    Research Infrastructure: CIISB II - 90127; CCP II - 90126
    Institutional support: RVO:61388971
    Keywords : Adenylate cyclase toxin * Bordetella pertussis * CAMP intoxication * Lung colonization * Lung inflammation * Pore-forming activity * RTX toxin * Virulence
    OECD category: Microbiology
    Impact factor: 5.923, year: 2020
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/22/21/11655
    Permanent Link: http://hdl.handle.net/11104/0325678
     
     
  3. 3.
    0547497 - MBÚ 2022 RIV DE eng J - Journal Article
    Lepesheva, Anna - Osičková, Adriana - Holubová, Jana - Jurnečka, David - Knoblochová, Šárka - Espinosa-Vinals, Carlos Angel - Bumba, Ladislav - Škopová, Karolína - Fišer, Radovan - Osička, Radim - Šebo, Peter - Mašín, Jiří
    Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins.
    Scientific Reports. Roč. 11, č. 1 (2021), č. článku 19814. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA MŠk(CZ) LM2018133; GA ČR(CZ) GA19-12695S; GA ČR(CZ) GX19-27630X; GA ČR(CZ) GA19-04607S
    Research Infrastructure: CIISB II - 90127
    Institutional support: RVO:61388971
    Keywords : adenylate-cyclase toxin * escherichia-coli hemolysin * bordetella-pertussis cyaa * cell-invasive activity * alpha-hemolysin * membrane translocation * complement receptor-3 * fatty-acylation * calcium * binding
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.379, year: 2020
    Method of publishing: Open access
    https://www.nature.com/articles/s41598-021-99112-3
    Permanent Link: http://hdl.handle.net/11104/0323712
     
     
  4. 4.
    0547494 - MBÚ 2022 RIV CH eng J - Journal Article
    Malandra, Anna - Rahman, Waheed Ur - Klímová, Nela - Streparola, Gaia - Holubová, Jana - Osičková, Adriana - Bariselli, S. - Šebo, Peter - Osička, Radim
    Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein.
    International Journal of Molecular Sciences. Roč. 22, č. 16 (2021), č. článku 9064. E-ISSN 1422-0067
    R&D Projects: GA ČR(CZ) GA19-12695S; GA ČR(CZ) GX19-27630X; GA MŠk(CZ) LM2018133; GA MŠk(CZ) LM2018126; GA MŠk EF18_046/0015861
    Research Infrastructure: CCP II - 90126
    Institutional support: RVO:61388971 ; RVO:68378050
    Keywords : adenylate cyclase toxin * Bordetella * cAMP * creb * epithelium * mucin * pertussis toxin
    OECD category: Microbiology
    Impact factor: 5.923, year: 2020
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/22/16/9064
    Permanent Link: http://hdl.handle.net/11104/0323707
     
     
  5. 5.
    0544756 - MBÚ 2022 RIV US eng J - Journal Article
    Espinosa-Vinals, Carlos Angel - Mašín, Jiří - Holubová, Jana - Staněk, Ondřej - Jurnečka, David - Osička, Radim - Šebo, Peter - Bumba, Ladislav
    Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin.
    Journal of Biological Chemistry. Roč. 297, č. 1 (2021), č. článku 100833. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA ČR(CZ) GA19-15175S; GA ČR(CZ) GA19-04607S; GA ČR(CZ) GX19-27630X; GA MŠk(CZ) LM2018133
    Institutional support: RVO:61388971
    Keywords : identification * translocation * secretion * acylation * membrane * delivery
    OECD category: Microbiology
    Impact factor: 5.157, year: 2020
    Method of publishing: Open access
    https://www.webofscience.com/wos/woscc/full-record/WOS:000678068400033
    Permanent Link: http://hdl.handle.net/11104/0321577
     
     
  6. 6.
    0541463 - MBÚ 2022 RIV CH eng J - Journal Article
    Knuutila, A. - Barkoff, A-M. - Mertsola, J. - Osička, Radim - Šebo, Peter - He, Q.
    Simultaneous Determination of Antibodies to Pertussis Toxin and Adenylate Cyclase Toxin Improves Serological Diagnosis of Pertussis.
    Diagnostics. Roč. 11, č. 2 (2021), č. článku 180. E-ISSN 2075-4418
    Institutional support: RVO:61388971
    Keywords : Pertussis * in vitro diagnostics * point-of-care * serology * lateral flow * multiplex
    OECD category: Microbiology
    Impact factor: 3.706, year: 2020
    Method of publishing: Open access
    https://www.mdpi.com/2075-4418/11/2/180
    Permanent Link: http://hdl.handle.net/11104/0319014
     
     
  7. 7.
    0536763 - MBÚ 2021 RIV CH eng J - Journal Article
    Rahman, Waheed Ur - Osičková, Adriana - Klímová, Nela - Lora, J. - Balashova, N. - Osička, Radim
    Binding of Kingella kingae RtxA Toxin Depends on Cell Surface Oligosaccharides, but Not on beta(2) Integrins.
    International Journal of Molecular Sciences. Roč. 21, č. 23 (2020), č. článku 9092. E-ISSN 1422-0067
    R&D Projects: GA ČR(CZ) GA18-18079S; GA MŠk(CZ) LM2018133
    Institutional support: RVO:61388971
    Keywords : integrins * Kingella kingae * oligosaccharides
    OECD category: Microbiology
    Impact factor: 5.923, year: 2020
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/21/23/9092
    Permanent Link: http://hdl.handle.net/11104/0314511
     
     
  8. 8.
    0535246 - MBÚ 2021 RIV CH eng J - Journal Article
    Staněk, Ondřej - Linhartová, Irena - Holubová, Jana - Bumba, Ladislav - Gardian, Zdenko - Malandra, Anna - Bočková, Barabora - Teruya, S. - Horiguchi, Y. - Osička, Radim - Šebo, Peter
    Production of Highly Active Recombinant Dermonecrotic Toxin ofBordetella Pertussis.
    Toxins. Roč. 12, č. 9 (2020), č. článku 596. ISSN 2072-6651. E-ISSN 2072-6651
    R&D Projects: GA ČR(CZ) GX19-27630X; GA ČR(CZ) GA19-12695S; GA MŠk(CZ) LM2018133
    Research Infrastructure: Czech-BioImaging - 90062
    Institutional support: RVO:61388971 ; RVO:60077344
    Keywords : Bordetella * GTPase * deamidation * dermonecrotic toxin * recombinant
    OECD category: Microbiology; Biochemical research methods (BC-A)
    Impact factor: 4.546, year: 2020
    Method of publishing: Open access
    https://www.mdpi.com/2072-6651/12/9/596
    Permanent Link: http://hdl.handle.net/11104/0313335
     
     
  9. 9.
    0533326 - MBÚ 2021 RIV US eng J - Journal Article
    Osičková, Adriana - Khaliq, Humaira - Mašín, Jiří - Jurnečka, David - Suková, Anna - Fišer, Radovan - Holubová, Jana - Staněk, Ondřej - Šebo, Peter - Osička, Radim
    Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins.
    Journal of Biological Chemistry. Roč. 295, č. 28 (2020), s. 9268-9280. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA MŠk(CZ) LM2018127
    Institutional support: RVO:61388971
    Keywords : acylation * acyltransferase * cytotoxicit
    OECD category: Microbiology
    Impact factor: 5.157, year: 2020
    Method of publishing: Open access
    Permanent Link: http://hdl.handle.net/11104/0311734
     
     
  10. 10.
    0533024 - MBÚ 2021 RIV US eng J - Journal Article
    Mašín, Jiří - Osičková, Adriana - Jurnečka, David - Klímová, Nela - Khaliq, Humaira - Šebo, Peter - Osička, Radim
    Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme?translocating segment ofBordetellaadenylate cyclase toxin.
    Journal of Biological Chemistry. Roč. 295, č. 28 (2020), s. 9349-9365. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA ČR(CZ) GA19-04607S; GA ČR(CZ) GA18-18079S; GA ČR(CZ) GA19-12695S; GA ČR(CZ) GA18-20621S; GA MŠk(CZ) LM2018133
    Institutional support: RVO:61388971
    Keywords : AC domain translocation * acylation * acyltransferase * fatty acyl * integrin * RTX toxin
    OECD category: Microbiology
    Impact factor: 5.157, year: 2020
    Method of publishing: Open access with time embargo
    https://www.jbc.org/content/early/2020/05/11/jbc.RA120.013630.short
    Permanent Link: http://hdl.handle.net/11104/0311527