Search results
- 1.0584603 - MBÚ 2025 RIV US eng J - Journal Article
Kašíková, L. - Raková, J. - Hensler, M. - Láníčková, T. - Tománková, J. - Pasulka, J. - Drozenová, J. - Mojžíšová, K. - Fialová, A. - Vošahlíková, Š. - Laco, J. - Ryška, A. - Dundr, P. - Kocián, R. - Brtnický, T. - Skapa, P. - Čapková, L. - Kovář, Marek - Procházka, Jan - Práznovec, I. - Koblížek, V. - Tasková, A. - Tanaka, H. - Lischke, R. - Mendez, F. C. - Vachtenheim, J. J. - Heinzelmann-Schwarz, V. - Jacob, F. - McNeish, I. A. - Halaška, M. J. - Rob, L. - Cibula, D. - Orsulic, S. - Galluzzi, L. - Spíšek, R. - Fučíková, J.
Tertiary lymphoid structures and B cells determine clinically relevant T cell phenotypes in ovarian cancer.
Nature Communications. Roč. 15, č. 1 (2024), s. 2528. E-ISSN 2041-1723
R&D Projects: GA MŠMT LX22NPO5102
Institutional support: RVO:61388971 ; RVO:68378050
Keywords : lymphoid structures * B cells * T cell * ovarian cancer
OECD category: Immunology
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41467-024-46873-w
Permanent Link: https://hdl.handle.net/11104/0352493File Download Size Commentary Version Access Tertiary lymphoid structures.pdf 0 13.1 MB Publisher’s postprint open-access - 2.0580702 - MBÚ 2025 RIV NL eng J - Journal Article
Kovář, Marek - Šubr, Vladimír - Běhalová, Kateřina - Studenovský, Martin - Starenko, Daniil - Kovářová, Jiřina - Procházková, Petra - Etrych, Tomáš - Kostka, Libor
Chemosensitization of tumors via simultaneous delivery of STAT3 inhibitor and doxorubicin through HPMA copolymer-based nanotherapeutics with pH-sensitive activation.
Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 56, February 2024 (2024), s. 102730. ISSN 1549-9634. E-ISSN 1549-9642
R&D Projects: GA MZd(CZ) NU21-03-00273; GA MŠMT LX22NPO5102
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : STAT3 inhibitor * Doxorubicin * HPMA copolymer carrier * pH-sensitive drug * release
OECD category: Pharmacology and pharmacy; Medicinal chemistry (UMCH-V)
Impact factor: 5.4, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1549963423000813
Permanent Link: https://hdl.handle.net/11104/0349459File Download Size Commentary Version Access 0580702.pdf 1 5 MB CC BY license Publisher’s postprint open-access Kovar et al_Nanomedicine.pdf 0 5 MB Publisher’s postprint open-access - 3.0578373 - ÚMG 2024 RIV GB eng J - Journal Article
Niederlová, Veronika - Tsyklauri, Oksana - Kovář, Marek - Štěpánek, Ondřej
IL-2-driven CD8+ T cell phenotypes: implications for immunotherapy.
Trends in Immunology. Roč. 44, č. 11 (2023), s. 890-901. ISSN 1471-4906. E-ISSN 1471-4981
R&D Projects: GA ČR GA22-21356S; GA ČR(CZ) GA22-20548S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT LX22NPO5102
EU Projects: European Commission(XE) 802878 - FunDiT
Research Infrastructure: e-INFRA CZ II - 90254
Institutional support: RVO:68378050 ; RVO:61388971
Keywords : cancer * cytotoxic T cells * il-2 * immunotherapy * pd-1 * regulatory T cell
OECD category: Immunology; Immunology (MBU-M)
Impact factor: 16.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1471490623001953?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0347367File Download Size Commentary Version Access Niederlova et al_Trends in Immunology.pdf 0 2 MB Publisher’s postprint open-access - 4.0571076 - MBÚ 2024 RIV DE eng J - Journal Article
Holíček, P. - Truxová, I. - Raková, J. - Šálek, C. - Hensler, M. - Kovář, Marek - Reiniš, Milan - Mikyšková, Romana - Pasulka, J. - Vošahlíková, Š. - Remešová, H. - Valentová, I. - Lysák, D. - Holubová, M. - Kašpar, Petr - Procházka, Jan - Kašíková, L. - Špíšek, R. - Galluzzi, L. - Fučiková, J.
Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients.
Cell Death & Disease. Roč. 14, č. 3 (2023), č. článku 209. ISSN 2041-4889. E-ISSN 2041-4889
R&D Projects: GA MŠMT LM2023036; GA MŠMT LX22NPO5102
Institutional support: RVO:61388971 ; RVO:68378050
Keywords : acute myeloid-leukemia * alpha * cells * metastasis * signature * radiation * rna
OECD category: Immunology; Cell biology (UMG-J)
Impact factor: 9, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41419-023-05728-w
Permanent Link: https://hdl.handle.net/11104/0342383File Download Size Commentary Version Access Type I interferon signaling.pdf 0 1.4 MB Publisher’s postprint open-access - 5.0569557 - ÚMG 2024 RIV GB eng J - Journal Article
Tsyklauri, Oksana - Chadimová, Tereza - Niederlová, Veronika - Kovářová, Jiřina - Michálik, Juraj - Malátová, Iva - Janušová, Šárka - Ivashchenko, Olha - Rossez, H. - Drobek, Aleš - Večeřová, Hana - Galati, V. - Kovář, Marek - Štěpánek, Ondřej
Regulatory T cells suppress the formation of potent KLRK1 and IL- 7R expressing effector CD8 T cells by limiting IL-2.
eLife. Roč. 12, Jan 27 (2023), č. článku e79342. ISSN 2050-084X. E-ISSN 2050-084X
R&D Projects: GA MŠMT(CZ) LX22NPO5103; GA MŠMT LX22NPO5102; GA ČR GJ19-03435Y; GA ČR(CZ) GA22-20548S; GA ČR GA22-18046S; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2018126; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
EU Projects: European Commission(XE) 802878 - FunDiT
Institutional support: RVO:68378050 ; RVO:61388971
Keywords : IL-2 * T cells * autoimmunity * cytotoxic * immune suppression * immunology * inflammation * mouse * regulatory T cells
OECD category: Immunology; Immunology (MBU-M)
Impact factor: 7.7, year: 2022
Method of publishing: Open access
https://elifesciences.org/articles/79342
Permanent Link: https://hdl.handle.net/11104/0340929File Download Size Commentary Version Access elife-Tsyklauri O.-2023.pdf 0 3.4 MB Publisher’s postprint open-access - 6.0565337 - ÚMCH 2024 RIV NL eng J - Journal Article
Kostka, Libor - Kotrchová, Lenka - Randárová, Eva - Ferreira, C. A. - Malátová, Iva - Lee, H. J. - Olson, A. P. - Engle, J. W. - Kovář, Marek - Cai, W. - Šírová, Milada - Etrych, Tomáš
Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models.
Journal of Controlled Release. Roč. 353, January (2023), s. 549-562. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) LTAUSA18083
Grant - others:AV ČR(CZ) MSM200502104
Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : drug delivery * cancer * polymeric carriers
OECD category: Polymer science; Pharmacology and pharmacy (MBU-M)
Impact factor: 10.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0168365922008148?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0336896File Download Size Commentary Version Access 0565337.pdf 0 8 MB Creative Commons Attribution 4.0 International License (CC BY) Publisher’s postprint open-access - 7.0563741 - MBÚ 2023 RIV CH eng J - Journal Article
Antošová, Z. - Podzimkova, N. - Tomala, Jakub - Augustýnková, K. - Sajnerová, K. - Nedvědová, E. - Šírová, Milada - de Martynoff, G. - Bechard, D. - Moebius, U. - Kovář, Marek - Špíšek, R. - Adkins, I.
SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity.
Frontiers in Immunology. Roč. 13, OCT 10 2022 (2022), č. článku 989895. ISSN 1664-3224. E-ISSN 1664-3224
Institutional support: RVO:61388971
Keywords : NK cells * antibody-dependent cytotoxicity * interleukin-15 * immunotherapy * therapeutic antibodies * rli-15
OECD category: Oncology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fimmu.2022.989895/full
Permanent Link: https://hdl.handle.net/11104/0335572 - 8.0559474 - ÚMCH 2023 RIV US eng J - Journal Article
Kousalová, Jana - Šírová, Milada - Kostka, Libor - Šubr, Vladimír - Kovářová, Jiřina - Běhalová, Kateřina - Studenovský, Martin - Kovář, Marek - Etrych, Tomáš
Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines.
Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 44, August (2022), č. článku 102578. ISSN 1549-9634. E-ISSN 1549-9642
R&D Projects: GA MŠMT(CZ) LTAUSA18083
Grant - others:AV ČR(CZ) JSPS-22-01
Program: Bilaterální spolupráce
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : matrix metalloproteinases * metastases * actinonin
OECD category: Polymer science; Oncology (MBU-M)
Impact factor: 5.4, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S1549963422000648?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0332758 - 9.0558143 - ÚMCH 2023 RIV CH eng J - Journal Article
Studenovský, Martin - Rumlerová, Anna - Kovářová, Jiřina - Dvořáková, Barbora - Sivák, Ladislav - Kostka, Libor - Berdár, Daniel - Etrych, Tomáš - Kovář, Marek
HPMA copolymer mebendazole conjugate allows systemic administration and possesses antitumour activity in vivo.
Pharmaceutics. Roč. 14, č. 6 (2022), č. článku 1201. E-ISSN 1999-4923
R&D Projects: GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LTAUSA18083
Grant - others:AV ČR(CZ) JSPS-22-01
Program: Bilaterální spolupráce
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : mebendazole * drug delivery * cancer therapy
OECD category: Polymer science; Pharmacology and pharmacy (MBU-M)
Impact factor: 5.4, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1999-4923/14/6/1201
Permanent Link: https://hdl.handle.net/11104/0333076 - 10.0558142 - ÚMCH 2023 RIV US eng J - Journal Article
Kostka, Libor - Sivák, Ladislav - Šubr, Vladimír - Kovářová, Jiřina - Šírová, Milada - Říhová, Blanka - Sedláček, Radislav - Etrych, Tomáš - Kovář, Marek
Simultaneous delivery of doxorubicin and protease inhibitor derivative to solid tumors via star-shaped polymer nanomedicines overcomes P-gp- and STAT3-mediated chemoresistance.
Biomacromolecules. Roč. 23, č. 6 (2022), s. 2522-2535. ISSN 1525-7797. E-ISSN 1526-4602
R&D Projects: GA ČR(CZ) GA19-05649S; GA MZd(CZ) NU21-03-00273; GA MŠMT(CZ) LTAUSA18083; GA MŠMT(CZ) LM2018126; GA MŠMT(CZ) ED1.1.00/02.0109
Research Infrastructure: CCP II - 90126
Institutional support: RVO:61389013 ; RVO:61388971 ; RVO:68378050
Keywords : HPMA * RAFT * star-like
OECD category: Polymer science; Microbiology (MBU-M); Genetics and heredity (medical genetics to be 3) (UMG-J)
Impact factor: 6.2, year: 2022
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.biomac.2c00256
Permanent Link: https://hdl.handle.net/11104/0332796