Search results

  1. 1.
    0572804 - FGÚ 2024 RIV US eng J - Journal Article
    Abramová, Vera - Leal Alvarado, Vanessa - Hill, M. - Smejkalová, Tereza - Malý, Michal - Valeš, Karel - Dittert, Ivan - Božíková, Paulina - Kysilov, Bohdan - Hrčka Krausová, Barbora - Vyklický, Vojtěch - Balík, Aleš - Fili, Klevinda - Kořínek, Miloslav - Chodounská, Hana - Kudová, Eva - Číž, D. - Martinovič, J. - Černý, Jiří - Bartůněk, Petr - Vyklický ml., Ladislav
    Effects of Pregnanolone Glutamate and Its Metabolites on GABAA and NMDA Receptors and Zebrafish Behavior.
    ACS Chemical Neuroscience. Roč. 14, č. 10 (2023), s. 1870-1883. ISSN 1948-7193. E-ISSN 1948-7193
    R&D Projects: GA MZd(CZ) EF16_025/0007444; GA MŠk LM2023052; GA ČR(CZ) GA23-04922S; GA TA ČR(CZ) TN02000109
    Research Infrastructure: CZ-OPENSCREEN IV - 90252
    Institutional support: RVO:67985823 ; RVO:86652036 ; RVO:61388963 ; RVO:68378050
    Keywords : negative allosteric modulator * thigmotaxis * steroid * glutamate * zebrafish
    OECD category: Neurosciences (including psychophysiology; Neurosciences (including psychophysiology (UOCHB-X); Biochemistry and molecular biology (UMG-J); Biochemistry and molecular biology (BTO-N)
    Impact factor: 5, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1021/acschemneuro.3c00131
    Permanent Link: https://hdl.handle.net/11104/0343402
     
     
  2. 2.
    0558978 - FGÚ 2023 RIV GB eng J - Journal Article
    Kysilov, Bohdan - Hrčka Krausová, Barbora - Vyklický, Vojtěch - Smejkalová, Tereza - Kořínek, Miloslav - Horák, Martin - Chodounská, Hana - Kudová, Eva - Černý, Jiří - Vyklický ml., Ladislav
    Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations.
    British Journal of Pharmacology. Roč. 179, č. 15 (2022), s. 3970-3990. ISSN 0007-1188. E-ISSN 1476-5381
    R&D Projects: GA ČR(CZ) GA20-17945S; GA MZd(CZ) EF16_025/0007444; GA TA ČR(CZ) TN01000013
    Institutional support: RVO:67985823 ; RVO:61388963
    Keywords : GRIN channelopathy * NMDA receptor * positive allosteric modulator * steroids * transmembrane domain
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 7.3, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1111/bph.15841
    Permanent Link: https://hdl.handle.net/11104/0332640
     
     
  3. 3.
    0555872 - FGÚ 2023 RIV GB eng J - Journal Article
    Štefková-Mazochová, K. - Danda, H. - Dehaen, W. - Jurásek, B. - Šíchová, K. - Pinterová-Leca, N. - Mazoch, V. - Hrčka Krausová, Barbora - Kysilov, Bohdan - Smejkalová, Tereza - Vyklický ml., Ladislav - Kohout, M. - Hájková, K. - Svozil, Daniel - Horsley, R. R. - Kuchař, M. - Páleníček, T.
    Pharmacokinetic, pharmacodynamic, and behavioural studies of deschloroketamine in Wistar rats.
    British Journal of Pharmacology. Roč. 179, č. 1 (2022), s. 65-83. ISSN 0007-1188. E-ISSN 1476-5381
    R&D Projects: GA ČR(CZ) GA20-17945S; GA MZd(CZ) EF16_025/0007444; GA MŠk(CZ) LM2018130
    Research Infrastructure: CZ-OPENSCREEN III - 90130
    Institutional support: RVO:67985823 ; RVO:68378050
    Keywords : deschloroketamine * enantiomers * locomotion * NMDA receptor * pharmacokinetics * pharmacokinetics
    OECD category: Pharmacology and pharmacy
    Impact factor: 7.3, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1111/bph.15680
    Permanent Link: http://hdl.handle.net/11104/0330327
     
     
  4. 4.
    0552392 - FGÚ 2022 RIV CH eng J - Journal Article
    Hirschfeldová, Kateřina - Černý, Jiří - Božíková, P. - Kuchtiak, Viktor - Rausch, T. - Beneš, V. - Španiel, F. - Greguš, D. - Horáček, J. - Vyklický ml., Ladislav - Balík, Aleš
    Evidence for the Association between the Intronic Haplotypes of Ionotropic Glutamate Receptors and First-Episode Schizophrenia.
    Journal of Personalized Medicine. Roč. 11, č. 12 (2021), č. článku 1250. E-ISSN 2075-4426
    R&D Projects: GA MŠk(CZ) LTAUSA19122; GA ČR(CZ) GA20-17945S; GA TA ČR(CZ) TN01000013; GA MZd(CZ) EF16_025/0007444; GA MŠk(CZ) LQ1604; GA MŠk(CZ) ED1.1.00/02.0109
    Research Infrastructure: e-INFRA CZ - 90140; ELIXIR-CZ II - 90131
    Institutional support: RVO:67985823
    Keywords : schizophrenia * ionotropic glutamate receptor * intron * genetic variations * SNP * haplotypes * scoring model * BrainAGE
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 3.508, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/2075-4426/11/12/1250
    Permanent Link: http://hdl.handle.net/11104/0327533
     
     
  5. 5.
    0546480 - FGÚ 2022 RIV GB eng J - Journal Article
    Smejkalová, Tereza - Kořínek, Miloslav - Krůšek, Jan - Hrčka Krausová, Barbora - Candelas Serra, Miriam - Hajduković, Dragana - Kudová, Eva - Chodounská, Hana - Vyklický ml., Ladislav
    Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms.
    British Journal of Pharmacology. Roč. 178, č. 19 (2021), s. 3888-3904. ISSN 0007-1188. E-ISSN 1476-5381
    R&D Projects: GA MZd(CZ) EF16_025/0007444; GA ČR(CZ) GJ16-03913Y; GA TA ČR(CZ) TN01000013; GA MŠk(CZ) LQ1604
    Institutional support: RVO:67985823 ; RVO:61388963
    Keywords : glutamate * Munc13-1 * neurosteroid * phorbol ester * pregnanolone * presynaptic
    OECD category: Neurosciences (including psychophysiology; Organic chemistry (UOCHB-X)
    Impact factor: 9.473, year: 2021
    Method of publishing: Open access
    https://doi.org/10.1111/bph.15529
    Permanent Link: http://hdl.handle.net/11104/0322979
     
     
  6. 6.
    0544687 - FGÚ 2022 RIV CH eng J - Journal Article
    Holubová, K. - Chvojková, M. - Hrčka Krausová, Barbora - Vyklický, Vojtěch - Kudová, Eva - Chodounská, Hana - Vyklický ml., Ladislav - Valeš, Karel
    Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia.
    Biomolecules. Roč. 11, č. 7 (2021), č. článku 1026. E-ISSN 2218-273X
    R&D Projects: GA MZd(CZ) EF16_025/0007444; GA ČR(CZ) GA20-17945S; GA ČR(CZ) GA18-09296S; GA MZd(CZ) NU20-04-00389
    Institutional support: RVO:67985823 ; RVO:61388963
    Keywords : neurosteroids * schizophrenia * MK-801 * cognition * anxiety * stress
    OECD category: Neurosciences (including psychophysiology; Organic chemistry (UOCHB-X)
    Impact factor: 6.064, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/2218-273X/11/7/1026
    Permanent Link: http://hdl.handle.net/11104/0321516
     
     
  7. 7.
    0541892 - FGÚ 2022 RIV US eng J - Journal Article
    Hubálková, Pavla - Ladislav, Marek - Vyklický, Vojtěch - Smejkalová, Tereza - Hrčka Krausová, Barbora - Kysilov, Bohdan - Krůšek, Jan - Naimová, Žaneta - Kořínek, Miloslav - Chodounská, Hana - Kudová, Eva - Černý, Jiří - Vyklický ml., Ladislav
    Palmitoylation Controls NMDA Receptor Function and Steroid Sensitivity.
    Journal of Neuroscience. Roč. 41, č. 10 (2021), s. 2119-2134. ISSN 0270-6474. E-ISSN 1529-2401
    R&D Projects: GA ČR(CZ) GA20-17945S; GA ČR(CZ) GJ16-03913Y; GA TA ČR(CZ) TN01000013; GA MŠk(CZ) LQ1604; GA MZd(CZ) EF16_025/0007444
    Institutional support: RVO:67985823 ; RVO:61388963
    Keywords : carboxy-terminal domain * molecular dynamics simulation * neurosteroid * NMDAR * palmitoylation * single-channel recording
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 6.709, year: 2021
    Method of publishing: Open access with time embargo
    https://doi.org/10.1523/JNEUROSCI.2654-20.2021
    Permanent Link: http://hdl.handle.net/11104/0319387
     
     
  8. 8.
    0531944 - FGÚ 2021 RIV US eng J - Journal Article
    Hrčka Krausová, Barbora - Kysilov, Bohdan - Černý, Jiří - Vyklický, Vojtěch - Smejkalová, Tereza - Ladislav, Marek - Balík, Aleš - Kořínek, Miloslav - Chodounská, Hana - Kudová, Eva - Vyklický ml., Ladislav
    Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor.
    Journal of Neuroscience. Roč. 40, č. 31 (2020), s. 5922-5936. ISSN 0270-6474. E-ISSN 1529-2401
    R&D Projects: GA ČR(CZ) GA17-02300S; GA ČR(CZ) GJ16-03913Y; GA TA ČR(CZ) TN01000013; GA ČR(CZ) GA20-17945S; GA MŠk(CZ) LQ1604
    Institutional support: RVO:67985823 ; RVO:61388963
    Keywords : glutamate receptors * neurosteroids * patch clamp * structure
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 6.167, year: 2020
    Method of publishing: Open access with time embargo
    https://doi.org/10.1523/JNEUROSCI.3010-19.2020
    Permanent Link: http://hdl.handle.net/11104/0310574
     
     
  9. 9.
    0531929 - FGÚ 2021 RIV GB eng J - Journal Article
    Kořínek, Miloslav - González-González, I. M. - Smejkalová, Tereza - Hajduković, Dragana - Skřenková, Kristýna - Krůšek, Jan - Horák, Martin - Vyklický ml., Ladislav
    Cholesterol modulates presynaptic and postsynaptic properties of excitatory synaptic transmission.
    Scientific Reports. Roč. 10, č. 1 (2020), č. článku 12651. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA ČR(CZ) GA17-02300S; GA ČR(CZ) GJ16-03913Y; GA TA ČR(CZ) TN01000013; GA MŠk(CZ) LQ1604
    Institutional support: RVO:67985823
    Keywords : synaptic transmission * cholesterol * NMDA receptor * NMDA receptor * neuroprotection * synapse * membrane
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 4.380, year: 2020
    Method of publishing: Open access
    https://www.nature.com/articles/s41598-020-69454-5
    Permanent Link: http://hdl.handle.net/11104/0310562
     
     
  10. 10.
    0517459 - FGÚ 2020 RIV CH eng J - Journal Article
    Černý, Jiří - Božíková, P. - Balík, Aleš - Marques, S. M. - Vyklický ml., Ladislav
    NMDA Receptor Opening and Closing-Transitions of a Molecular Machine Revealed by Molecular Dynamics.
    Biomolecules. Roč. 9, č. 10 (2019), č. článku 546. E-ISSN 2218-273X
    R&D Projects: GA ČR(CZ) GA17-02300S; GA TA ČR(CZ) TN01000013; GA MŠk(CZ) ED1.1.00/02.0109
    Research Infrastructure: CESNET II - 90042; CERIT-SC - 90085; ELIXIR-CZ - 90047
    Institutional support: RVO:67985823
    Keywords : glutamate receptor gating * molecular modeling * molecular dynamics simulations * NMDA receptor transition * open and closed state
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 4.082, year: 2019
    Method of publishing: Open access
    https://doi.org/10.3390/biom9100546
    Permanent Link: http://hdl.handle.net/11104/0302760
     
     

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