Search results
- 1.0583813 - FGÚ 2024 RIV CZ cze L - Prototype, f. module
Mlejnek, Petr - Šilhavý, Jan - Pravenec, Michal
Knokautovaní potkani kmene SHR/Ola s delecí Hif1a (hypoxia inducible factor 1 subunit alpha) genu.
[Strain of knockout rats SHR/Ola with deletion of Hif1a (hypoxia inducible factor 1 subunit alpha) gene.]
Internal code: SHR.SD-Hif1a KO ; 2023
Technical parameters: SHR.SD-Hif1a KO
Economic parameters: 20000Kč
R&D Projects: GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:67985823
Keywords : Knockout SHR * rat * Hif1a gene * hypoxia
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Permanent Link: https://hdl.handle.net/11104/0351809 - 2.0583808 - FGÚ 2024 RIV CZ cze L - Prototype, f. module
Mlejnek, Petr - Šilhavý, Jan - Pravenec, Michal
Knokautovaní potkani kmene SHR/Ola s delecí Bdnf (brain derived neurotrophic factor) genu.
[Strain of knockout rats SHR/Ola with deletion of Bdnf (brain derived neurotrophic factor) gene.]
Internal code: SHR.SD-Bdnf KO ; 2023
Technical parameters: SHR.SD-Bdnf KO
Economic parameters: 20000Kč
R&D Projects: GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:67985823
Keywords : Knockout SHR * rat * Bdnf gene * metabolism * energy balance
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Permanent Link: https://hdl.handle.net/11104/0351807 - 3.0472729 - FGÚ 2017 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L. - Silberová, P.
Transgenní potkani převedení do SPF kvality linie SHR/Ola-Tg(Pnmt-BN Pnmt)76Ipcv s cDNA genu Pnmt (phenylethanolamine-N-methyltransferase) pod kontrolou endogenního promotoru z kmene BN (Brown Norway), získaní pomocí transpozonového vektoru Sleeping Beauty a SB100X hyperaktivní transpozázy.
[Line of transgenic rats SHR/Ola-Tg(Pnmt-BN Pnmt)76Ipcv with cDNA of Pnmt (phenylethanolamine-N-methyltransferase) gene under control of an endogenous promoter of BN (Brown Norway) strain obtained by using the Sleeping Beauty transposon vector and SB100X hyperactive transposase rederived into SPF quality.]
Internal code: SPF SHR/Ola-Tg(Pnmt-BN Pnmt)76Ipcv ; 2016
Technical parameters: SPF SHR/Ola-Tg(Pnmt-BN Pnmt)76Ipcv
Economic parameters: 20000Kč
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : SPF * transgenic SHR * Pnmt (phenylethanolamine-N-methyltransferase) * Sleeping Beauty transposon vector
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0269960 - 4.0472727 - FGÚ 2017 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L. - Silberová, P.
Transgenní potkani převedení do kvality SPF linie SHR/Ola-Tg(Dbh-Dbh)611Ipcv s cDNA genu Dbh (dopamine beta hydroxylase) pod kontrolou endogenního promotoru z kmene BN (Brown Norway), získaní pomocí transpozonového vektoru Sleeping Beauty a SB100X hyperaktivní transpozázy.
[Line of trangenic rats SHR/Ola-Tg(Dbh-Dbh)611Ipcv with cDNA of Dbh (dopamine beta hydroxylase) gene under control of an endogenous promoter of BN (Brown Norway) strain obtained by using the Sleeping Beauty transposon vector and SB100X hyperactive transposase, rederived into SPF quality.]
Internal code: SPF SHR/Ola-Tg(Dbh-Dbh)611Ipcv ; 2016
Technical parameters: SPF SHR/Ola-Tg(Dbh-Dbh)611Ipcv. Jedná se o SHR kmen se zvýšenou expresí Dbh transgenu specificky v nadledvině (Pravenec a spol, Physiological Research 65:1039-1044, 2016)
Economic parameters: 20000Kč
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : SPF * transgenic SHR * Dbh (dopamine beta hydroxylase) * Sleeping Beauty transposon vector
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0269957 - 5.0472720 - FGÚ 2017 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L. - Silberová, P.
Transgenní potkani převedení do kvality SPF kmene SHR/Ola-Tg(EF1a-Endog)128Ipcv exprimující Endog (endonuclease G) gen (cDNA kmene BN) pod kontrolou všeobecného EF-1alfa promotoru.
[Strain of transgenic rats SHR/Ola expressing Endog (endonuclease G) gene (cDNA of BN origin) under control of general EF-1alpha promoter rederived into SPF quality.]
Internal code: SPF SHR/Ola-(EF1a-Endog(BN cDNA))128Ipcv ; 2016
Technical parameters: SPF SHR/Ola-(EF1a-Endog(BN cDNA))128Ipcv
Economic parameters: 20000Kč
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : SPF * transgenic SHR * Endog gene * left ventricular hypertrophy
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0269950 - 6.0452393 - FGÚ 2016 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L.
Transgenní potkani linie SHR/Ola-Tg(Dbh-Dbh)611Ipcv s cDNA genu Dbh (dopamine beta hydroxylase) pod kontrolou endogenního promotoru z kmene BN (Brown Norway), získaní pomocí transpozonového vektoru Sleeping Beauty a SB100X hyperaktivní transpozázy.
[Line of trangenic rats SHR/Ola-Tg(Dbh-Dbh)611Ipcv with cDNA of Dbh (dopamine beta hydroxylase) gene under control of an endogenous promoter of BN (Brown Norway) strain obtained by using the Sleeping Beauty transposon vector and SB100X hyperactive transposase.]
Internal code: SHR/Ola-Tg(Dbh-Dbh)611Ipcv ; 2015
Technical parameters: Dosud nepublikovaný výsledek. Jedná se o SHR kmen se zvýšenou expresí Dbh transgenu specificky v nadledvině
Economic parameters: Využití pro navazující výzkum a zvýšení objemu výroby
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : transgenic SHR * Dbh (dopamine beta hydroxylase) * Sleeping Beauty transposon vector
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0253403 - 7.0452390 - FGÚ 2016 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L.
Transgenní potkani linie SHR/Ola-Tg(Pnmt-BN Pnmt)76Ipcv s cDNA genu Pnmt (phenylethanolamine-N-methyltransferase) pod kontrolou endogenního promotoru z kmene BN (Brown Norway), získaní pomocí transpozonového vektoru Sleeping Beauty a SB100X hyperaktivní transpozázy.
[Line of transgenic rats SHR/Ola-Tg(Pnmt-BN Pnmt)76Ipcv with cDNA of Pnmt (phenylethanolamine-N-methyltransferase) gene under control of an endogenous promoter of BN (Brown Norway) strain obtained by using the Sleeping Beauty transposon vector and SB100X hyperactive transposase.]
Internal code: SHR/Ola-Tg(Pnmt-BN Pnmt)76Ipcv ; 2015
Technical parameters: SHR/Ola-Tg(Pnmt-BN Pnmt)76Ipcv
Economic parameters: Využití pro navazující výzkum a zvýšení objemu výroby
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : transgenic SHR * Pnmt (phenylethanolamine-N-methyltransferase) * Sleeping Beauty transposon vector
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0253404 - 8.0452387 - FGÚ 2016 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L.
Transgenní potkani kmene SHR/Ola exprimující Endog (endonuclease G) gen (cDNA kmene BN) pod kontrolou všeobecného EF-1alfa promotoru.
[Strain of transgenic rats SHR/Ola expressing Endog (endonuclease G) gene (cDNA of BN origin) under control of general EF-1alpha promoter.]
Internal code: SHR/Ola-(EF1a-Endog(BN cDNA))128Ipcv ; 2015
Technical parameters: SHR/Ola-(EF1a-Endog(BN cDNA))128Ipcv
Economic parameters: Využití pro navazující výzkum a zvýšení objemu výroby
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : transgenic SHR * Endog gene * left ventricular hypertrophy * metabolic disturbances
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0253405 - 9.0439925 - FGÚ 2015 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L.
Transgenní potkani kmene SHR/Ola s mCherry genem z korálovníku pod kontrolou všeobecného promotoru, získaní pomocí transpozonového vektoru Sleeping Beauty v kombinaci s RMCE (recombinase mediated casette exchange) kazetou - SHR/Ola-(RMCE-mCherry).
[Strain of transgenic rats SHR/Ola with mCherry gene from Discosoma sp. under control of a universal promoter obtained by using the Sleeping Beauty transposon vector with RMCE (recombinase mediated casette exchange) – SHR/Ola-(RMCE-mCherry).]
Internal code: SHR/Ola-(RMCE-mCherry) ; 2014
Technical parameters: SHR/Ola-(RMCE-mCherry)
Economic parameters: 20000Kč
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : Transgenic SHR * mCherry fluorescent protein * Sleeping Beauty transposon vector with RMCE
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0243160 - 10.0439923 - FGÚ 2015 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L.
Transgenní potkani kmene SHR/Ola s cDNA genu Pnmt (phenylethanolamine-N-methyltransferase) pod kontrolou endogenního promotoru z kmene BN (Brown Norway), získaní pomocí transpozonového vektoru Sleeping Beauty a SB100X hyperaktivní transpozázy.
[Strain of transgenic rats SHR/Ola with cDNA of Pnmt(phenylethanolamine-N-methyltransferase)gene under control of an endogenous promoter of BN(Brown Norway)strain obtained by using the Sleeping Beauty transposon vector and SB100X hyperactive transposase.]
Internal code: SHR/Ola-Tg(Pnmt-Pnmt) ; 2014
Technical parameters: SHR/Ola-Tg(Pnmt-Pnmt)
Economic parameters: 20000Kč
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : Transgenic SHR * Pnmt (phenylethanolamine-N-methyltransferase) * Sleeping Beauty transposon vector
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0243159