Search results
- 1.0574564 - FGÚ 2024 RIV NL eng J - Journal Article
Alquezar-Artieda, N. - Kužílková, D. - Roberts, J. - Hložková, K. - Pecinová, Alena - Pecina, Petr - Zwyrtková, M. - Potůčková, E. - Kavan, Daniel - Heřmanová, I. - Žaliová, M. - Novák, Petr - Mráček, Tomáš - Šrámková, L. - Tennant, D. A. - Trka, J. - Starková, J.
Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy.
Blood Advances. Roč. 7, č. 10 (2023), s. 2228-2236. ISSN 2473-9529. E-ISSN 2473-9537
R&D Projects: GA ČR(CZ) GA21-18993S; GA MŠMT LX22NPO5102
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : cancer metabolism * L-asparaginase * leukemia * resistance * glycolysis * fatty acid oxidation * MSCs * biosynthetic pathways
OECD category: Endocrinology and metabolism (including diabetes, hormones); Biochemistry and molecular biology (MBU-M)
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1182/bloodadvances.2021006431
Permanent Link: https://hdl.handle.net/11104/0345499File Download Size Commentary Version Access Restored biosynthetic pathways.pdf 2 1 MB Publisher’s postprint open-access - 2.0562623 - FGÚ 2023 RIV NL eng J - Journal Article
Pak, O. - Nolte, A. - Knoepp, F. - Giordano, L. - Pecina, Petr - Hüttemann, M. - Grossman, L. I. - Weissmann, N. - Sommer, N.
Mitochondrial oxygen sensing of acute hypoxia in specialized cells- Is there a unifying mechanism?
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1863, č. 8 (2022), č. článku 148911. ISSN 0005-2728. E-ISSN 1879-2650
Institutional support: RVO:67985823
Keywords : oxygen sensor * hypoxia * mitochondria * PASMC * carotid body * Cox4i2
OECD category: Biochemistry and molecular biology
Impact factor: 4.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bbabio.2022.148911
Permanent Link: https://hdl.handle.net/11104/0335466 - 3.0555857 - FGÚ 2023 RIV CH eng J - Journal Article
Marković, Aleksandra - Tauchmannová, Kateřina - Šimáková, Miroslava - Mlejnek, Petr - Kaplanová, Vilma - Pecina, Petr - Pecinová, Alena - Papoušek, František - Liška, František - Šilhavý, Jan - Mikešová, Jana - Neckář, Jan - Houštěk, Josef - Pravenec, Michal - Mráček, Tomáš
Genetic Complementation of ATP Synthase Deficiency Due to Dysfunction of TMEM70 Assembly Factor in Rat.
Biomedicines. Roč. 10, č. 2 (2022), č. článku 276. E-ISSN 2227-9059
R&D Projects: GA ČR(CZ) GA20-25768S; GA MZd(CZ) NU21-07-00550
Grant - others:AV ČR(CZ) AP1502
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:67985823
Keywords : mitochondria disease * ATP synthase deficiency * TMEM70 factor * transgenic rescue * gene therapy
OECD category: Biochemistry and molecular biology
Impact factor: 4.7, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2227-9059/10/2/276
Permanent Link: http://hdl.handle.net/11104/0330319 - 4.0541622 - FGÚ 2022 RIV CH eng J - Journal Article
Čunátová, Kristýna - Pajuelo-Reguera, David - Vrbacký, Marek - Fernández-Vizarra, E. - Ding, SJ. - Fearnley, I.M. - Zeviani, M. - Houštěk, Josef - Mráček, Tomáš - Pecina, Petr
Loss of COX4I1 Leads to Combined Respiratory Chain Deficiency and Impaired Mitochondrial Protein Synthesis.
Cells. Roč. 10, č. 2 (2021), č. článku 369. E-ISSN 2073-4409
R&D Projects: GA ČR(CZ) GA16-13671S; GA MZd(CZ) NV19-07-00149; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:67985823
Keywords : mitochondria * OXPHOS * cI * COX * cIV * COX4 * knock-out * cIV assembly * complex I * biogenesis interdependency * complexome profiling * mitochondrial protein synthesis
OECD category: Biochemistry and molecular biology
Impact factor: 7.666, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2073-4409/10/2/369
Permanent Link: http://hdl.handle.net/11104/0319155 - 5.0536893 - FGÚ 2021 RIV CZ eng J - Journal Article
Čunátová, Kristýna - Pajuelo-Reguera, David - Houštěk, Josef - Mráček, Tomáš - Pecina, Petr
Role of cytochrome c oxidase nuclear-encoded subunits in health and disease.
Physiological Research. Roč. 69, č. 6 (2020), s. 947-965. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA16-13671S; GA MZd(CZ) NV19-07-00149
Institutional support: RVO:67985823
Keywords : mitochondria * OXPHOS * cytochrome c oxidase * nuclear-encoded subunits * mitochondrial diseases
OECD category: Biochemistry and molecular biology
Impact factor: 1.881, year: 2020
Method of publishing: Open access
https://www.biomed.cas.cz/physiolres/pdf/2020/69_947.pdf
Permanent Link: http://hdl.handle.net/11104/0314645 - 6.0532976 - FGÚ 2021 RIV CH eng J - Journal Article
Pecinová, Alena - Alán, Lukáš - Brázdová, Andrea - Vrbacký, Marek - Pecina, Petr - Drahota, Zdeněk - Houštěk, Josef - Mráček, Tomáš
Role of Mitochondrial Glycerol-3-Phosphate Dehydrogenase in Metabolic Adaptations of Prostate Cancer.
Cells. Roč. 9, č. 8 (2020), č. článku 1764. E-ISSN 2073-4409
R&D Projects: GA ČR(CZ) GA16-12726S; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:AV ČR(CZ) StrategieAV21/7
Program: StrategieAV
Institutional support: RVO:67985823
Keywords : GPD2 gene * mitochondrial glycerol-3-phosphate dehydrogenase (EC:1.1.5.3) * prostate cancer * metabolic adaptation
OECD category: Biochemistry and molecular biology
Impact factor: 6.600, year: 2020
Method of publishing: Open access
https://www.mdpi.com/2073-4409/9/8/1764
Permanent Link: http://hdl.handle.net/11104/0311482 - 7.0524126 - FGÚ 2021 RIV CH eng J - Journal Article
Pajuelo-Reguera, David - Čunátová, Kristýna - Vrbacký, Marek - Pecinová, Alena - Houštěk, Josef - Mráček, Tomáš - Pecina, Petr
Cytochrome c Oxidase Subunit 4 Isoform Exchange Results in Modulation of Oxygen Affinity.
Cells. Roč. 9, č. 2 (2020), č. článku 443. E-ISSN 2073-4409
R&D Projects: GA ČR(CZ) GA16-13671S; GA MZd(CZ) NV17-28784A
Institutional support: RVO:67985823
Keywords : mitochondria * OXPHOS * respiratory chain * cytochrome c oxidase * COX * COX4 isoforms * COX4i2 * oxygen affinity * p(50) * oxygen sensing
OECD category: Biochemistry and molecular biology
Impact factor: 6.600, year: 2020
Method of publishing: Open access
https://www.mdpi.com/2073-4409/9/2/443
Permanent Link: http://hdl.handle.net/11104/0308474 - 8.0523845 - FGÚ 2021 RIV US eng J - Journal Article
Nůsková, Hana - Mikešová, Jana - Efimova, Iuliia - Pecinová, Alena - Pecina, Petr - Drahota, Zdeněk - Houštěk, Josef - Mráček, Tomáš
Biochemical thresholds for pathological presentation of ATP synthase deficiencies.
Biochemical and Biophysical Research Communications. Roč. 521, č. 4 (2020), s. 1036-1041. ISSN 0006-291X. E-ISSN 1090-2104
R&D Projects: GA ČR(CZ) GA16-01813S; GA MZd(CZ) NV16-33018A
Institutional support: RVO:67985823
Keywords : ATP synthase * deficiency * reactive oxygen species * oxidative phosphorylation * threshold effect
OECD category: Biochemistry and molecular biology
Impact factor: 3.575, year: 2020
Method of publishing: Limited access
https://doi.org/10.1016/j.bbrc.2019.11.033
Permanent Link: http://hdl.handle.net/11104/0308123 - 9.0520774 - FGÚ 2020 RIV US eng J - Journal Article
Kovalčíková, Jana - Vrbacký, Marek - Pecina, Petr - Tauchmannová, Kateřina - Nůsková, Hana - Kaplanová, Vilma - Brázdová, Andrea - Alán, Lukáš - Eliáš, Jan - Čunátová, Kristýna - Kořínek, Vladimír - Sedláček, Radislav - Mráček, Tomáš - Houštěk, Josef
TMEM70 facilitates biogenesis of mammalian ATP synthase by promoting subunit c incorporation into the rotor structure of the enzyme.
FASEB Journal. Roč. 33, č. 12 (2019), s. 14103-14117. ISSN 0892-6638. E-ISSN 1530-6860
R&D Projects: GA ČR(CZ) GB14-36804G; GA MZd(CZ) NV16-33018A; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:67985823 ; RVO:68378050
Keywords : mouse knockout * mitochondria * ancillary factor * ATP5G assembly
OECD category: Genetics and heredity (medical genetics to be 3)
Impact factor: 4.966, year: 2019
Method of publishing: Limited access
https://doi.org/10.1096/fj.201900685RR
Permanent Link: http://hdl.handle.net/11104/0305447 - 10.0490333 - FGÚ 2019 RIV NL eng J - Journal Article
Pecina, Petr - Nůsková, Hana - Karbanová, Vendula - Kaplanová, Vilma - Mráček, Tomáš - Houštěk, Josef
Role of the mitochondrial ATP synthase central stalk subunits gamma and delta in the activity and assembly of the mammalian enzyme.
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1859, č. 5 (2018), s. 374-381. ISSN 0005-2728. E-ISSN 1879-2650
R&D Projects: GA ČR(CZ) GB14-36804G; GA MZd(CZ) NV16-33018A
Institutional support: RVO:67985823
Keywords : ATP synthase * deficiency * knockdown * gamma and delta subunits * subunit c aggregates
OECD category: Biochemistry and molecular biology
Impact factor: 4.441, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284578