Search results

  1. 1.
    0642116 - FGÚ 2027 DE eng J - Journal Article
    Danačíková, Šárka - Pecina, Petr - Pecinová, Alena - Svoboda, J. - Vondrášek, David - Basello, Davide Alessandro - Čajka, Tomáš - Hadraba, Daniel - Mráček, Tomáš - Kořínek, Vladimír - Otáhal, Jakub
    Development of Cellular Energy Metabolism During Differentiation of Human iPSCs into Cortical Neurons.
    Molecular Neurobiology. Roč. 63, č. 1 (2026), č. článku 37. ISSN 0893-7648. E-ISSN 1559-1182
    R&D Projects: GA MŠMT(CZ) LX22NPO5107; GA ČR(CZ) GA22-28265S
    Institutional support: RVO:67985823 ; RVO:68378050
    Keywords : human iPSCs * neuronal differentiation * cellular bioenergetics * respirometry * proteomics * metabolic flux analysis
    OECD category: Neurosciences (including psychophysiology
    Impact factor: 4.3, year: 2024 ; AIS: 1.083, rok: 2024
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1007/s12035-025-05284-8DOI: https://doi.org/10.1007/s12035-025-05284-8
    Permanent Link: https://hdl.handle.net/11104/0372660
     
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    26_0002_0642116.pdf02.7 MBPublisher’s postprintopen-access
     
  2. 2.
    0636605 - ÚMG 2026 RIV US eng J - Journal Article
    Líblová, Zuzana - Maurencová, Dominika - Šalovská, Barbora - Krátký, Marek - Mráček, Tomáš - Korandová, Zuzana - Pecinová, Alena - Vašicová, Pavla - Ryšánek, David - Anděra, Ladislav - Fabrik, I. - Kupčík, R. - Kashmel, Pavel - Sultana, Pinky - Tambor, V. - Bártek, Jiří - Novák, Josef - Vajrychová, M. - Hodný, Zdeněk
    Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence.
    Molecular Oncology. Roč. 19, č. 9 (2025), s. 2619-2647. ISSN 1574-7891. E-ISSN 1878-0261
    R&D Projects: GA ČR GA20-15728S; GA ČR(CZ) GA24-11357S; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LX22NPO5104
    Institutional support: RVO:68378050 ; RVO:67985823
    Keywords : ADP/ATP translocase * cellular senescence * glioblastoma * targeted mass spectrometry
    OECD category: Oncology
    Impact factor: 4.5, year: 2024 ; AIS: 1.53, rok: 2024
    Method of publishing: Open access
    Result website:
    https://febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70039DOI: https://doi.org/10.1002/1878-0261.70039
    Permanent Link: https://hdl.handle.net/11104/0372284
     
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    Liblova_0636605.pdf0629 KBPublisher’s postprintopen-access
     
  3. 3.
    0619841 - FGÚ 2026 RIV US eng J - Journal Article
    Alán, Lukáš - Opletalová, Barbora - Hayat, Habiba - Marković, Aleksandra - Hlaváčková, Markéta - Vrbacký, Marek - Mráček, Tomáš - Alánová, Petra
    Mitochondrial metabolism and hypoxic signaling in differentiated human cardiomyocyte AC16 cell line.
    American Journal of Physiology-Cell Physiology. Roč. 328, č. 5 (2025), C1571-C1585. ISSN 0363-6143. E-ISSN 1522-1563
    R&D Projects: GA ČR(CZ) GA23-06027S; GA MŠMT(CZ) LX22NPO5104
    Institutional support: RVO:67985823
    Keywords : ac16 * differentiation * hypoxia * metabolism * mitochondria
    OECD category: Cell biology
    Impact factor: 4.7, year: 2024 ; AIS: 1.431, rok: 2024
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1152/ajpcell.00083.2025DOI: https://doi.org/10.1152/ajpcell.00083.2025
    Permanent Link: https://hdl.handle.net/11104/0366738
     
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    25_0048_0619841.pdf25.6 MBPublisher’s postprintopen-access
     
  4. 4.
    0605156 - FGÚ 2026 RIV NL eng J - Journal Article
    Korandová, Zuzana - Pecina, Petr - Pecinová, Alena - Koňaříková, Eliška - Tesařová, M. - Houštěk, Josef - Hansíková, H. - Ptáčková, H. - Zeman, J. - Honzík, T. - Mráček, Tomáš
    Cryopreserved PBMCs can be used for the analysis of mitochondrial respiration and serve as a diagnostic tool for mitochondrial diseases.
    Analytical Biochemistry. Roč. 698, March (2025), č. článku 115745. ISSN 0003-2697. E-ISSN 1096-0309
    R&D Projects: GA ČR(CZ) GA20-25768S; GA MZd(CZ) NU22-01-00499; GA MŠMT(CZ) LX22NPO5104
    Institutional support: RVO:67985823
    Keywords : respirometry * mitochondrial diseases * cryopreservation * OXPHOS * oxidative phosphorylation * peripheral blood mononuclear cells * PBMC * glycolysis * diagnostics
    OECD category: Biochemistry and molecular biology
    Impact factor: 2.5, year: 2024 ; AIS: 0.5, rok: 2024
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1016/j.ab.2024.115745DOI: https://doi.org/10.1016/j.ab.2024.115745
    Permanent Link: https://hdl.handle.net/11104/0363485
     
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    25_0003_0605156.pdf05.8 MBPublisher’s postprintopen-access
     
  5. 5.
    0599893 - FGÚ 2025 RIV DE eng J - Journal Article
    Miklovič, M. - Gawrys, O. - Honetschlägerová, Z. - Kala, P. - Husková, Z. - Kikerlová, S. - Vaňourková, Z. - Jíchová, Š. - Kvasilová, A. - Kitamoto, M. - Maxová, H. - Puertas-Frias, Guillermo - Mráček, Tomáš - Sedmera, D. - Melenovský, V.
    Renal denervation improves cardiac function independently of afterload and restores myocardial norepinephrine levels in a rodent heart failure model.
    Hypertension Research. Roč. 47, October (2024), s. 2718-2730. ISSN 0916-9636. E-ISSN 1348-4214
    R&D Projects: GA MŠMT(CZ) LX22NPO5104
    Institutional support: RVO:67985823
    Keywords : heart failure * norepinephrine * renal denervation * volume overload * sympathetic nervous system
    OECD category: Cardiac and Cardiovascular systems
    Impact factor: 4.6, year: 2024 ; AIS: 0.948, rok: 2024
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1038/s41440-024-01580-3DOI: https://doi.org/10.1038/s41440-024-01580-3
    Permanent Link: https://hdl.handle.net/11104/0357317
     
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    24_0121_0599893.pdf73.6 MBPublisher’s postprintopen-access
     
  6. 6.
    0599352 - FGÚ 2025 RIV GB eng J - Journal Article
    Pecina, Petr - Čunátová, Kristýna - Kaplanová, Vilma - Puertas-Frias, Guillermo - Šilhavý, Jan - Tauchmannová, Kateřina - Vrbacký, Marek - Čajka, Tomáš - Gahura, Ondřej - Hlaváčková, Markéta - Stránecký, V. - Kmoch, S. - Pravenec, Michal - Houštěk, Josef - Mráček, Tomáš - Pecinová, Alena
    Haplotype variability in mitochondrial rRNA predisposes to metabolic syndrome.
    Communications Biology. Roč. 7, č. 1 (2024), č. článku 1116. E-ISSN 2399-3642
    R&D Projects: GA ČR(CZ) GA19-10354S; GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) LUAUS23095; GA MŠMT(CZ) EH22_008/0004575
    Research Infrastructure: NCMG III - 90267
    Institutional support: RVO:67985823 ; RVO:60077344 ; RVO:68378050
    Keywords : energy metabolism * metabolic syndrome * metabolomics * proteomics
    OECD category: Endocrinology and metabolism (including diabetes, hormones); Biochemistry and molecular biology (BC-A)
    Impact factor: 5.1, year: 2024 ; AIS: 2.063, rok: 2024
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1038/s42003-024-06819-wDOI: https://doi.org/10.1038/s42003-024-06819-w
    Permanent Link: https://hdl.handle.net/11104/0356836
     
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    24_0116_0599352.pdf84.2 MBPublisher’s postprintopen-access
     
  7. 7.
    0598238 - FGÚ 2025 RIV US eng J - Journal Article
    Čunátová, Kristýna - Vrbacký, Marek - Puertas-Frias, Guillermo - Alán, Lukáš - Vanišová, M. - Saucedo-Rodríguez, María José - Houštěk, Josef - Fernández-Vizarra, E. - Neužil, Jiří - Pecinová, Alena - Pecina, Petr - Mráček, Tomáš
    Mitochondrial translation is the primary determinant of secondary mitochondrial complex I deficiencies.
    iScience. Roč. 27, č. 8 (2024), č. článku 110560. E-ISSN 2589-0042
    R&D Projects: GA MŠMT(CZ) EF18_046/0016045; GA ČR(CZ) GA21-18993S; GA ČR(CZ) GA22-21082S; GA MŠMT(CZ) LX22NPO5104; GA MZd(CZ) NU22-01-00499
    Research Infrastructure: Czech-BioImaging III - 90250
    Institutional support: RVO:67985823 ; RVO:86652036 ; RVO:68378050
    Keywords : oxidative phosphorylation system (OXPHOS) * ATP synthase * biogenesis * mitochondria
    OECD category: Endocrinology and metabolism (including diabetes, hormones); Endocrinology and metabolism (including diabetes, hormones) (BTO-N)
    Impact factor: 4.1, year: 2024 ; AIS: 1.395, rok: 2024
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1016/j.isci.2024.110560DOI: https://doi.org/10.1016/j.isci.2024.110560
    Permanent Link: https://hdl.handle.net/11104/0355965
     
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    24_0076_0598238.pdf97.1 MBPublisher’s postprintopen-access
     
  8. 8.
    0598040 - FGÚ 2025 RIV CZ eng J - Journal Article
    Tauchmannová, Kateřina - Pecinová, Alena - Houštěk, Josef - Mráček, Tomáš
    Variability of Clinical Phenotypes Caused by Isolated Defects of Mitochondrial ATP Synthase.
    Physiological Research. Roč. 73, Suppl.1 (2024), S243-S278. ISSN 0862-8408. E-ISSN 1802-9973
    R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA ČR(CZ) GA21-18993S; GA MZd(CZ) NU21-07-00550
    Institutional support: RVO:67985823
    Keywords : mitochondrial diseases * ATP synthase * nuclear DNA * mitochondrial DNA * TMEM70
    OECD category: Biochemistry and molecular biology
    Impact factor: 2, year: 2024 ; AIS: 0.497, rok: 2024
    Method of publishing: Open access
    Result website:
    https://www.biomed.cas.cz/physiolres/pdf/2024/73_S243.pdf

    DOI: https://doi.org/10.33549/physiolres.935407
    Permanent Link: https://hdl.handle.net/11104/0355810
     
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    24_0091_0598040.pdf42.1 MBPublisher’s postprintopen-access
     
  9. 9.
    0583232 - FGÚ 2025 RIV US eng J - Journal Article
    Šilhavý, Jan - Mlejnek, Petr - Šimáková, Miroslava - Liška, František - Malínská, H. - Marková, I. - Hüttl, M. - Miklánková, D. - Mušálková, D. - Stránecký, V. - Kmoch, S. - Sticová, E. - Vrbacký, Marek - Mráček, Tomáš - Pravenec, Michal
    Spontaneous nonsense mutation in the tuftelin 1 gene is associated with abnormal hair appearance and amelioration of glucose and lipid metabolism in the rat.
    Physiological Genomics. Roč. 56, č. 1 (2024), s. 65-73. ISSN 1094-8341. E-ISSN 1531-2267
    R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) LUAUS23095; GA ČR(CZ) GA21-18993S
    Research Infrastructure: NCMG III - 90267
    Institutional support: RVO:67985823
    Keywords : hepatic proteome * lipid and glucose metabolism * rat * spontaneous nonsense mutation * tuftelin 1 gene * Tuft1
    OECD category: Cardiac and Cardiovascular systems
    Impact factor: 2.5, year: 2024 ; AIS: 0.855, rok: 2024
    Method of publishing: Open access with time embargo
    Result website:
    https://doi.org/10.1152/physiolgenomics.00084.2023DOI: https://doi.org/10.1152/physiolgenomics.00084.2023
    Permanent Link: https://hdl.handle.net/11104/0351234
     
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    24_0012_0583232.pdf62 MBPublisher’s postprintopen-access
     
  10. 10.
    0582380 - BTÚ 2025 RIV US eng J - Journal Article
    Sharma, P. - Maklashina, E. - Voehler, M. - Bálintová, Soňa - Dvořáková, Šárka - Kraus, Michal - Váňová Hadrava, Kateřina - Nahácka, Zuzana - Zobalová, Renata - Boukalová, Štěpána - Čunátová, Kristýna - Mráček, Tomáš - Ghayee, H. K. - Pacak, K. - Rohlena, Jakub - Neužil, Jiří - Cecchini, G. - Iverson, T. M.
    Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners.
    Nature Communications. Roč. 15, č. 1 (2024), č. článku 473. ISSN 2041-1723. E-ISSN 2041-1723
    R&D Projects: GA MZd(CZ) NU23-03-00226; GA ČR(CZ) GA23-05303S; GA ČR(CZ) GJ20-11724Y; GA ČR GA19-20553S; GA ČR(CZ) GX21-04607X; GA ČR(CZ) GA20-05942S; GA ČR(CZ) GA20-25768S
    Institutional support: RVO:86652036 ; RVO:67985823
    Keywords : onset optic atrophy * succinate-dehydrogenase * crystal-structure * structural basis * chemical-shifts
    OECD category: Biochemistry and molecular biology; Cell biology (FGU-C)
    Impact factor: 15.7, year: 2024 ; AIS: 5.611, rok: 2024
    Method of publishing: Open access
    Result website:
    https://www.nature.com/articles/s41467-023-44563-7DOI: https://doi.org/10.1038/s41467-023-44563-7
    Permanent Link: https://hdl.handle.net/11104/0353431
     
     

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